
Moderna's flu vaccine hits goal, paving way for combo shot
Shares rose as much as 5.8 percent at the start of normal trading on Monday in New York.
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Moderna believes packaging the two immunizations together will lead to higher uptake of COVID vaccines. Nearly half of American adults get an annual flu shot, while only about 23 percent got the latest COVID vaccine.
Moderna's flu shot, which uses mRNA technology, also could contribute to a longtime public health goal: a better standalone flu shot. That mission has only become more urgent after the US just experienced by some measures its worst flu season in 15 years. This year's flu vaccines were 56 percent effective.
The company will seek approval for both its standalone flu shot and its COVID-flu combination vaccine, said Jacqueline Miller, Moderna's chief medical officer.
The flu vaccine 'is such a central component of our strategy,' Miller said in an interview, adding that a combination COVID-flu shot could entice someone who 'is put off by getting two injections at once.'
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Moderna's technology can make vaccines faster than the standard method, which requires growing the live virus in chicken eggs then inactivating it. That could make it easier to match the vaccine to the dominant strains that are circulating each season.
The results are a rare bright spot for a company that has struggled with the decline of its COVID business and more recently, the new leadership of Health and Human Services Secretary Robert F. Kennedy Jr., a vaccine critic. Under Kennedy, US health officials have rolled back long-standing recommendations around COVID shots for children and pregnant women, approved Moderna's updated COVID shot for a narrower group of people and terminated the company's contract to develop bird flu vaccines.
After the bird flu vaccine contract cancellation, the company has been 'actively seeking other funding sources' and is considering advancing the vaccine on its own, Miller said.
Moderna's flu program has been on a tumultuous path. Over two years ago, the company's standalone flu vaccine yielded mixed results. Several months later, the company reported that a reformulated version produced a stronger immune response. Last year, the company said it would focus its resources on seeking approval for a flu and COVID combination vaccine because it said it would have a bigger impact.
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Business Insider
37 minutes ago
- Business Insider
I'm 80 and still working. I've filed for bankruptcy twice and only have $37 in my savings account, but I feel blessed.
This as-told-to essay is based on a conversation with Sandy McConnell, 80, who lives in Nevada. McConnell works as a full-time accounts receivable specialist, earning about $50,000 annually. She has $37 in savings and over $70,000 in debt, not including her house. Business Insider has verified McConnell's current income and financial situation with documentation. This interview has been edited for length and clarity. Sometimes, I feel it's sad that people like me are still working so late in life, whether it be because we didn't manage money better, were never taught how to do so, or had circumstances that hindered our financial goals. I have to work because I've been single since 1997 and have a house payment, a car payment, and high credit card debt. I didn't take a 401(k) with my current company because I thought it was stupid to; I need the money now, not 10 years from now. Are you an older American comfortable sharing your retirement outlook with a reporter? Please fill out this quick form. We are especially interested in hearing from people 80 and older. On the other hand, if I didn't work, what would I do? I can't sit home all day — I would go nuts. Sure, I don't have the freedom to travel, but there are pros like keeping my brain active. I started working as a teenager When I was 16, I got my first part-time job as a cashier. I got married in 1962 and had a baby the following year. I tried going back to school, but I went to a Catholic school, and the nuns weren't having any of that. My husband was in the Navy, and I worked as a full-time checker while he was deployed. When he came back, I became pregnant again. After having that child, I worked in another grocery store as the head cashier and at the customer service desk. Through the 1960s, I held a few other grocery jobs, doing accounts receivable for one and doing collections work for Sears Roebuck. My last child was born in 1971. My husband left when my kids were little, and he wouldn't pay child support. Financially, I was always strapped, raising five children. I went through the training to be a nurse's aide, but realized quickly it wasn't for me. With my experience in consumer collections, I got a job a few years later at a jewelry store as a credit manager. Then I became a credit manager at a construction company, a role I held for many years. I held various credit management jobs while in Las Vegas, such as for automobile, roofing, and lighting companies. I lost my job at a building supply company right before COVID hit. I had to file for bankruptcy I've always been living paycheck to paycheck and never had a lot in savings. In 2001, I had 13 family members living with me due to unfortunate circumstances. They finally found work and got their own places, but that hurt me financially to the point where I've had to file for bankruptcy once in 2004 and most recently in October 2021. In 2022, my youngest son was living with me. We had previously had a falling out, but when he said things weren't going well, I told him he always had a place to stay. After being out of work, he got a really good job as a city bus driver and was helping me financially. One day, he never came home from work. He had collapsed from a massive heart attack. My oldest son and my grandson came to live with me after that. My oldest son was constantly changing jobs. In December 2023, he had a major stroke and couldn't work, and I had to take out credit cards to support my grandson. That really set me back financially. My son didn't have insurance at the time, and I also had to make sure he had his medications and got to therapy. Please help BI improve our Business, Tech, and Innovation coverage by sharing a bit about your role — it will help us tailor content that matters most to people like you. By providing this information, you agree that Business Insider may use this data to improve your site experience and for targeted advertising. By continuing you agree that you accept the Terms of Service and Privacy Policy . He and his son moved back to Oklahoma to be with his dad in June 2024. My daughter moved in with me the following month due to a nasty divorce. She's doing great and has a good job. She helps me financially. I don't have anybody right now to have to take care of, except for myself and my dogs. I've never thought I could retire Now I find myself at 80 still needing to work. Part of that is financial, and part of it is because I would be bored; if you don't have any money to do anything with, what are you going to do? Your house can only get so clean. I work as a full-time accounts receivable specialist. It's a very busy position, and I earn around $50,000 a year. I work from home, which I love. 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USA Today
42 minutes ago
- USA Today
Liberals call Trump a clown. But he's winning where it matters most.
I have a hunch that history will show that the first months of Donald Trump's second term as president were the beginning of an American resurgence. Picture this: It's 2045 in America. Stock markets are setting record highs, the economy is adding jobs, workers' salaries are increasing and tax rates are falling. Americans feel safer because our nation's borders are secure, the president has taken decisive action to reduce the threat of a nuclear war and warring factions in the Middle East are finally ready to discuss peace. What would you call such an encouraging set of indicators? To me, that sounds a lot like the America I want to live in. You might even call it a golden age of American strength. Here's great news: We don't have to wait 20 years. All of this and more is happening now, only five months after the start of Donald Trump's second term as president. Not bad for a guy who progressives have dismissed as a clown. Since June 22, Trump has set back Iran's development of nuclear weapons, forged a ceasefire between Iran and Israel, cajoled NATO allies into increasing spending on their own defense and pushed Canada to drop a digital services tax that hurt U.S. companies. Are you proud to be an American? Tell us what patriotism means to you. | Opinion Forum Trump tax cuts, Big Beautiful Bill will help American workers Trump also has racked up significant wins on the domestic front. The Senate is on the verge of passing the president's One Big Beautiful Bill Act, and if the House concurs, the legislation could be on Trump's desk by July 4, Friday. I wish that the bill cut more spending, but the White House Council of Economic Advisers projects that the tax provisions in the legislation would raise take-home pay by as much as $13,300 for a family of four and boost wages by as much as $11,600 per worker. Both would be tremendous wins for ordinary Americans. Trump's critics claimed that federal job cuts orchestrated by the Department of Government Efficiency would lead to a spike in unemployment, but the economy added a higher than expected 139,000 jobs in May and unemployment remained at a historically low 4.2%. Many of those critics also screamed that Trump's tariffs would blow up inflation and crash the economy. But inflation this year is on track for its lowest rate of increase in five years, and the fears of recession appear to be fading. Investors have noticed all of this good news. The S&P 500 and the Nasdaq are at record highs. And the running of the bulls appears to be just getting started. 'The wall of worry is crumbling as stocks reach all-time highs,' Terry Sandven of U.S. Bank Wealth Management told CNBC. 'Inflation is stable, interest rates are range-bound and earnings are trending higher. That's a favorable backdrop for stocks to continue to forge higher as we begin the second half.' Opinion: Conservatives report better mental health than liberals. I think I know why. Trump secures the border and slows illegal immigration In only five months, Trump has regained control of our southern border. Customs and Border Protection recently reported that the agency released zero illegal immigrants into the United States in May. A year ago, more than 62,000 people who entered our country illegally were allowed to stay. I don't think Trump is directly responsible for all of this winning. The stock markets, after all, have been on a rapid climb upward for years. At the same time, I know that if Democratic presidential nominee Kamala Harris had won in 2024 and accomplished half of these milestones, progressives, Democrats and the news media would be talking about where to build her monument on the National Mall. But because Trump is a Republican, they can't allow themselves to acknowledge his win streak. Still, I have a hunch that history will show that the first months of Trump's second term were the beginning of an American resurgence. Nicole Russell is an opinion columnist with USA TODAY. She lives in Texas with her four kids. Sign up for her newsletter, The Right Track, and get it delivered to your inbox.

Business Insider
an hour ago
- Business Insider
Self-made billionaire John Calamos says young people need to hustle — and have a mission in life — to be successful
John Calamos says young people need to work hard to succeed, but it's OK to change course in life. The billionaire investor and former Air Force pilot shared his advice for young people with BI. Calamos said that having a mission in life is vital, and wealth often comes as you work toward it. Self-made billionaire John Calamos says the road to success can be steep and winding, and wealthy parents should teach their kids that finding meaning in life trumps money. Calamos, 84, grew up in an apartment above his Greek-American family's grocery store, where he started working at a young age. He piloted jets during the Vietnam War before building his business empire. He's the founder of Calamos Investments, which manages assets worth more than $40 billion. Calamos, who published a biography, "The Sky's the Limit," in April, shared his advice for young people and parents with Business Insider. Forge your own path Calamos joined the military after taking to heart President John F. Kennedy's appeal for people to "ask not what your country can do for you; ask what you can do for your country." The convertible-bond pioneer has a similar message for graduates: "You don't get out of school now and say, 'OK, what is the government going to give me?'" he said. "It's not what the government's going to give you, it's what you can do." Calamos said that he was able to become wealthy despite modest beginnings by being "creative, innovative." Being determined and having goals are key to achieving great things, he added. In his book, he writes that young people shouldn't bow to pressure to specialize early, as he found value in a "more winding path." Calamos started off as an engineering student, studied philosophy, switched to architecture, graduated with a degree in economics, then later earned an MBA. "It's OK to change course as you learn more about yourself — what you truly care about and what ignites your passion," he writes. Calamos added that it's crucial to keep learning, stay curious, and look for better ways to do things at every stage of one's career. "This focus on continual improvement, innovation, and learning has been key to my own success," he writes. Hard work and hustle Calamos shared one of his biggest takeaways from his childhood and suggested how affluent parents might avoid raising entitled children. "What I learned from my parents was just a work ethic," he told BI. "They worked hard all the time." Calamos began working from a young age, first stocking shelves in his family's store, later delivering groceries and newspapers, washing windows, and more. A parent's job isn't to simply hand money to their children, it's to instill in them the values of hard work and perseverance, he added. He said that the message should be, "It's not about the money, it's about the mission — the money is a byproduct."