Revolutionary late-stage melanoma treatment sees survival rates surge
Your web browser is no longer supported. To improve your experience update it here A revolution in the treatment of late-stage melanoma has been reached, with clinical trial results seeing surging survival rates. Doctors are confident the new therapy approach, which will be subsidised by the Pharmaceutical Benefits Scheme (PBS), will overhaul the treatment of many types of deadly cancers. A tumour the size of a golf ball saw death come knocking for Matthew Croxford. A revolution in the treatment of late-stage melanoma has been reached with clinical trial results seeing surging survival rates (Nine) "You think - is this it?" the 52-year-old father-of-two told 9News. "And I had a lot of things to still achieve in my life." Croxford was offered to take part in an Australian and Netherlands-driven trial. The new therapy has flipped the cancer paradigm on its head, by giving the body the best opportunity to activate its own cancer-fighting defences. "It's like the sniffer dogs that find the fruit and veg and drugs at the airport, they're trained against what they need to find," The Melanoma Institute's Professor Georgina Long said. "By giving immunotherapy before surgery, we train our immune system better against the cancer," she said. A new therapy has flipped the cancer paradigm on its head by giving the body the best opportunity to activate its own cancer-fighting defences. (Nine) Of the 423 patients with Stage 3 melanoma, one group received usual treatment with surgery first, then a single immunotherapy drug. That order was then flipped for the other group, who were given two immunotherapy drugs first to shrink the tumour before surgery. "Their chance of the melanoma coming back is next to zero - it's less than five per cent," Long said. Such revolutionary results have seen the treatment approved to be funded by the PBS - a world first. Matthew Croxford was offered to take part in an Australian and Netherlands-driven trial. (Nine) Australia has the highest rates of melanoma in the world, with one person diagnosed every 30 minutes and a life lost every six hours because of the disease. Advances in treatment like this shift a diagnosis that has often been a death sentence to promising odds of survival. "I'm effectively cancer-free, I have no side effects whatsoever, and I'm incredibly fortunate," Croxford said. "It's like the sniffer dogs that find the fruit and veg and drugs at the airport, they're trained against what they need to find," The Melanoma Institute's Professor Georgina Long said. (Nine) The radical overhaul of traditional treatment is now being explored for other cancers, including lung, triple-negative breast cancer, kidney, head and neck cancers. This new treatment for Stage 3 melanoma patients is to be listed on the PBS within months. national
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The Advertiser
9 hours ago
- The Advertiser
What's gambling cost? Advocates slam political inaction
Australia risks losing a whole generation of kids to gambling, as criticisms are levelled at the government for failing to implement reforms from a landmark report two years on. The "You win some, you lose more" parliamentary inquiry into online gambling and its impacts, chaired by fierce gambling reform advocate the late Peta Murphy MP, delivered 31 recommendations in 2023. The unanimously supported proposals focused on reducing harm, protecting children and applying a long-overdue public health approach to gambling in this country. But two years to the day, gambling reform advocates, health bodies and church groups say the federal government have been silent. More than 80 per cent of Australians want a gambling advertisement ban, and parents are sick of turning on the TV only to find their 10-year-olds discussing the game in terms of odds, Alliance for Gambling Reform chief advocate Tim Costello said. "Smoking is legal, but kids shouldn't be seeing it. Same with gambling. People can gamble, but there's grooming of kids," Rev Costello told AAP. "We now have, with the two-year implementation (delay), a whole generation of kids who only think of NRL and AFL in terms of odds." Gambling harms lead to suicides, one-in-four 18-to-24-year-old young men are addicted, 600,000 underage Australians gambled last year, and domestic violence spikes threefold if there is gambling in a family, Rev Costello said. "This industry has been treated as having a normal social license when it's actually pushing very addictive products," he said. "We have literally given our kids over to sports betting companies as fodder for their profits." Vested interests, including the AFL and NRL, sports betting companies, and the commercial broadcasting networks, had stalled reforms, Rev Costello said. The nation's peak body for doctors, the Australian Medical Association, is demanding the government immediately action all 31 recommendations, accusing it of exposing millions of Australians to predatory betting companies. "Every day of delay means more Australians fall victim to an industry that profits from harm and despair," AMA President Danielle McMullen said. Wesley Mission chief executive Stu Cameron expressed deep disappointment in the government's failure to act on a bipartisan road map to tackle gambling harm."Two years on, the silence from Canberra is deafening," Rev Cameron said. "While the government hesitates, lives are being torn apart." The three say the government must use their parliamentary mandate to make systematic reforms, including banning gambling ads, implementing a national regulator and treating gambling as a health issue. A spokesman for Communications Minister Anika Wells said she has had several meetings with harm reduction advocates, broadcasters and sporting codes. He said the government had delivered "some of the most significant gambling harm reduction measures in Australian history", pointing to mandatory ID verification and banning credit cards for online gambling and launching BetStop, the National Self-Exclusion Register. Australians top the list for the world's highest gambling losses, placing $244.3 billion in bets every year. National Gambling Helpline 1800 858 858 Lifeline 13 11 14 beyondblue 1300 22 4636 1800 RESPECT (1800 737 732) Men's Referral Service 1300 766 491 Australia risks losing a whole generation of kids to gambling, as criticisms are levelled at the government for failing to implement reforms from a landmark report two years on. The "You win some, you lose more" parliamentary inquiry into online gambling and its impacts, chaired by fierce gambling reform advocate the late Peta Murphy MP, delivered 31 recommendations in 2023. The unanimously supported proposals focused on reducing harm, protecting children and applying a long-overdue public health approach to gambling in this country. But two years to the day, gambling reform advocates, health bodies and church groups say the federal government have been silent. More than 80 per cent of Australians want a gambling advertisement ban, and parents are sick of turning on the TV only to find their 10-year-olds discussing the game in terms of odds, Alliance for Gambling Reform chief advocate Tim Costello said. "Smoking is legal, but kids shouldn't be seeing it. Same with gambling. People can gamble, but there's grooming of kids," Rev Costello told AAP. "We now have, with the two-year implementation (delay), a whole generation of kids who only think of NRL and AFL in terms of odds." Gambling harms lead to suicides, one-in-four 18-to-24-year-old young men are addicted, 600,000 underage Australians gambled last year, and domestic violence spikes threefold if there is gambling in a family, Rev Costello said. "This industry has been treated as having a normal social license when it's actually pushing very addictive products," he said. "We have literally given our kids over to sports betting companies as fodder for their profits." Vested interests, including the AFL and NRL, sports betting companies, and the commercial broadcasting networks, had stalled reforms, Rev Costello said. The nation's peak body for doctors, the Australian Medical Association, is demanding the government immediately action all 31 recommendations, accusing it of exposing millions of Australians to predatory betting companies. "Every day of delay means more Australians fall victim to an industry that profits from harm and despair," AMA President Danielle McMullen said. Wesley Mission chief executive Stu Cameron expressed deep disappointment in the government's failure to act on a bipartisan road map to tackle gambling harm."Two years on, the silence from Canberra is deafening," Rev Cameron said. "While the government hesitates, lives are being torn apart." The three say the government must use their parliamentary mandate to make systematic reforms, including banning gambling ads, implementing a national regulator and treating gambling as a health issue. A spokesman for Communications Minister Anika Wells said she has had several meetings with harm reduction advocates, broadcasters and sporting codes. He said the government had delivered "some of the most significant gambling harm reduction measures in Australian history", pointing to mandatory ID verification and banning credit cards for online gambling and launching BetStop, the National Self-Exclusion Register. Australians top the list for the world's highest gambling losses, placing $244.3 billion in bets every year. National Gambling Helpline 1800 858 858 Lifeline 13 11 14 beyondblue 1300 22 4636 1800 RESPECT (1800 737 732) Men's Referral Service 1300 766 491 Australia risks losing a whole generation of kids to gambling, as criticisms are levelled at the government for failing to implement reforms from a landmark report two years on. The "You win some, you lose more" parliamentary inquiry into online gambling and its impacts, chaired by fierce gambling reform advocate the late Peta Murphy MP, delivered 31 recommendations in 2023. The unanimously supported proposals focused on reducing harm, protecting children and applying a long-overdue public health approach to gambling in this country. But two years to the day, gambling reform advocates, health bodies and church groups say the federal government have been silent. More than 80 per cent of Australians want a gambling advertisement ban, and parents are sick of turning on the TV only to find their 10-year-olds discussing the game in terms of odds, Alliance for Gambling Reform chief advocate Tim Costello said. "Smoking is legal, but kids shouldn't be seeing it. Same with gambling. People can gamble, but there's grooming of kids," Rev Costello told AAP. "We now have, with the two-year implementation (delay), a whole generation of kids who only think of NRL and AFL in terms of odds." Gambling harms lead to suicides, one-in-four 18-to-24-year-old young men are addicted, 600,000 underage Australians gambled last year, and domestic violence spikes threefold if there is gambling in a family, Rev Costello said. "This industry has been treated as having a normal social license when it's actually pushing very addictive products," he said. "We have literally given our kids over to sports betting companies as fodder for their profits." Vested interests, including the AFL and NRL, sports betting companies, and the commercial broadcasting networks, had stalled reforms, Rev Costello said. The nation's peak body for doctors, the Australian Medical Association, is demanding the government immediately action all 31 recommendations, accusing it of exposing millions of Australians to predatory betting companies. "Every day of delay means more Australians fall victim to an industry that profits from harm and despair," AMA President Danielle McMullen said. Wesley Mission chief executive Stu Cameron expressed deep disappointment in the government's failure to act on a bipartisan road map to tackle gambling harm."Two years on, the silence from Canberra is deafening," Rev Cameron said. "While the government hesitates, lives are being torn apart." The three say the government must use their parliamentary mandate to make systematic reforms, including banning gambling ads, implementing a national regulator and treating gambling as a health issue. A spokesman for Communications Minister Anika Wells said she has had several meetings with harm reduction advocates, broadcasters and sporting codes. He said the government had delivered "some of the most significant gambling harm reduction measures in Australian history", pointing to mandatory ID verification and banning credit cards for online gambling and launching BetStop, the National Self-Exclusion Register. Australians top the list for the world's highest gambling losses, placing $244.3 billion in bets every year. National Gambling Helpline 1800 858 858 Lifeline 13 11 14 beyondblue 1300 22 4636 1800 RESPECT (1800 737 732) Men's Referral Service 1300 766 491 Australia risks losing a whole generation of kids to gambling, as criticisms are levelled at the government for failing to implement reforms from a landmark report two years on. The "You win some, you lose more" parliamentary inquiry into online gambling and its impacts, chaired by fierce gambling reform advocate the late Peta Murphy MP, delivered 31 recommendations in 2023. The unanimously supported proposals focused on reducing harm, protecting children and applying a long-overdue public health approach to gambling in this country. But two years to the day, gambling reform advocates, health bodies and church groups say the federal government have been silent. More than 80 per cent of Australians want a gambling advertisement ban, and parents are sick of turning on the TV only to find their 10-year-olds discussing the game in terms of odds, Alliance for Gambling Reform chief advocate Tim Costello said. "Smoking is legal, but kids shouldn't be seeing it. Same with gambling. People can gamble, but there's grooming of kids," Rev Costello told AAP. "We now have, with the two-year implementation (delay), a whole generation of kids who only think of NRL and AFL in terms of odds." Gambling harms lead to suicides, one-in-four 18-to-24-year-old young men are addicted, 600,000 underage Australians gambled last year, and domestic violence spikes threefold if there is gambling in a family, Rev Costello said. "This industry has been treated as having a normal social license when it's actually pushing very addictive products," he said. "We have literally given our kids over to sports betting companies as fodder for their profits." Vested interests, including the AFL and NRL, sports betting companies, and the commercial broadcasting networks, had stalled reforms, Rev Costello said. The nation's peak body for doctors, the Australian Medical Association, is demanding the government immediately action all 31 recommendations, accusing it of exposing millions of Australians to predatory betting companies. "Every day of delay means more Australians fall victim to an industry that profits from harm and despair," AMA President Danielle McMullen said. Wesley Mission chief executive Stu Cameron expressed deep disappointment in the government's failure to act on a bipartisan road map to tackle gambling harm."Two years on, the silence from Canberra is deafening," Rev Cameron said. "While the government hesitates, lives are being torn apart." The three say the government must use their parliamentary mandate to make systematic reforms, including banning gambling ads, implementing a national regulator and treating gambling as a health issue. A spokesman for Communications Minister Anika Wells said she has had several meetings with harm reduction advocates, broadcasters and sporting codes. He said the government had delivered "some of the most significant gambling harm reduction measures in Australian history", pointing to mandatory ID verification and banning credit cards for online gambling and launching BetStop, the National Self-Exclusion Register. Australians top the list for the world's highest gambling losses, placing $244.3 billion in bets every year. National Gambling Helpline 1800 858 858 Lifeline 13 11 14 beyondblue 1300 22 4636 1800 RESPECT (1800 737 732) Men's Referral Service 1300 766 491
Perth Now
9 hours ago
- Perth Now
What's gambling cost? Advocates slam political inaction
Australia risks losing a whole generation of kids to gambling, as criticisms are levelled at the government for failing to implement reforms from a landmark report two years on. The "You win some, you lose more" parliamentary inquiry into online gambling and its impacts, chaired by fierce gambling reform advocate the late Peta Murphy MP, delivered 31 recommendations in 2023. The unanimously supported proposals focused on reducing harm, protecting children and applying a long-overdue public health approach to gambling in this country. But two years to the day, gambling reform advocates, health bodies and church groups say the federal government have been silent. More than 80 per cent of Australians want a gambling advertisement ban, and parents are sick of turning on the TV only to find their 10-year-olds discussing the game in terms of odds, Alliance for Gambling Reform chief advocate Tim Costello said. "Smoking is legal, but kids shouldn't be seeing it. Same with gambling. People can gamble, but there's grooming of kids," Rev Costello told AAP. "We now have, with the two-year implementation (delay), a whole generation of kids who only think of NRL and AFL in terms of odds." Gambling harms lead to suicides, one-in-four 18-to-24-year-old young men are addicted, 600,000 underage Australians gambled last year, and domestic violence spikes threefold if there is gambling in a family, Rev Costello said. "This industry has been treated as having a normal social license when it's actually pushing very addictive products," he said. "We have literally given our kids over to sports betting companies as fodder for their profits." Vested interests, including the AFL and NRL, sports betting companies, and the commercial broadcasting networks, had stalled reforms, Rev Costello said. The nation's peak body for doctors, the Australian Medical Association, is demanding the government immediately action all 31 recommendations, accusing it of exposing millions of Australians to predatory betting companies. "Every day of delay means more Australians fall victim to an industry that profits from harm and despair," AMA President Danielle McMullen said. Wesley Mission chief executive Stu Cameron expressed deep disappointment in the government's failure to act on a bipartisan road map to tackle gambling harm."Two years on, the silence from Canberra is deafening," Rev Cameron said. "While the government hesitates, lives are being torn apart." The three say the government must use their parliamentary mandate to make systematic reforms, including banning gambling ads, implementing a national regulator and treating gambling as a health issue. A spokesman for Communications Minister Anika Wells said she has had several meetings with harm reduction advocates, broadcasters and sporting codes. He said the government had delivered "some of the most significant gambling harm reduction measures in Australian history", pointing to mandatory ID verification and banning credit cards for online gambling and launching BetStop, the National Self-Exclusion Register. Australians top the list for the world's highest gambling losses, placing $244.3 billion in bets every year. National Gambling Helpline 1800 858 858 Lifeline 13 11 14 beyondblue 1300 22 4636 1800 RESPECT (1800 737 732) Men's Referral Service 1300 766 491
News.com.au
11 hours ago
- News.com.au
Aussie girl Marleigh, 10, talks to A Current Affair about new blood donation rules
A 10-year old Australian girl who relies on blood donations to stay alive says she has a better chance at life from new rules that allow gay and bisexual men and transgender women to donate plasma. Mum Kate told A Current Affair her daughter Marleigh relies on blood donations because of an incurable condition that is potentially fatal and has no cure. Kate fought for years to have the rules changed in Australia that would allow more people to donate lifesaving plasma. Kate said Marleigh suffered seizures that lasted up to almost 40 hours and their gay male friends were heartbroken they could not donate blood when the young girl was at her sickest. 'Her immune system is wrongly identifying her healthy brain cells as foreign and attacking her brain,' she said. 'We have so many friends, particularly our gay male friends, who would love to donate for Marleigh. 'All they wanted to do was go and jump in a seat at Lifeblood and donate the blood.' According to Lifeblood, earlier rules prevented gay and bisexual men and transgender women from donating blood or plasma if they had sex with men in the past three months. Lifeblood will remove most sexual activity wait times for plasma donations from July 14, which means most people, and anyone who takes pre-exposure prophylaxis that meets other eligibility criteria, will be able to donate plasma. The lifesaving organisation expects an extra 24,000 Australians will be able to give about 95,000 donations of plasma each year. Lifeblood chief medical officer Jo Pink said with plasma now the donation type most needed by Australian patients, the change came at an important time. 'We're excited to be able to welcome more people from across the community into our donor centres from next month,' she said. Dr Pink said the Therapeutic Goods Administration was also in the process of approving their submission to remove gender-based sexual activity rules, which means all donors will be asked the same rules about their sexual activity. She said their submission to change rules for blood donation included data that showed a six month wait was the safest option for Australian patients. 'But we are committed to reviewing this as more evidence becomes available,' she said. 'There are many steps that Lifeblood needs to take before we can implement the new gender-neutral assessments, including working with state and territory governments to change the donor questionnaire. 'We hope to be able to implement this part of the changes next year. 'Blood safety is and always will be our top priority but we know the current donation rules have been very difficult for many people in the LGBTQIA+ community. 'While they were put in place to ensure a safe blood supply in the past, we know that they've contributed to the stigma faced by the community.' Health Equity Matters chief executive officer Dash Heath-Paynter said he welcomed this change that could unlock thousands of donations of lifesaving plasma. 'While there is still more work, the Therapeutic Goods Administration's approval for gender neutral assessments for blood donation is welcomed,' he said. 'In terms of plasma donations, these changes mean Australia's regulations are world-leading.' Kirby Institute head of global health program John Kaldor said Lifeblood had developed pragmatic and innovative new procedures for blood donations with scientific evidence that shifted societal expectations.
