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Defending RFK Jr.'s Adviser

Defending RFK Jr.'s Adviser

In your editorial 'Meet RFK Jr.'s Vaccine Advisers' (June 13), you write of the secretary's new plans for the Advisory Committee on Immunization Practices: 'One appointee, Retsef Levi, is an MIT business school professor of operations management. What does he know about vaccines?' Allow me to rise to my colleague's defense.
The members of ACIP don't develop vaccines. They are charged with assessing their safety and efficacy. That is done through statistics and data science, areas in which Mr. Levi excels. His assessments will be conducted through vaccine trials, using a statistically significant number of participants and correlating the efficacy with a host of variables such as age, comorbidity, gender and dosage. The primary tool available to the researchers is statistical modeling. Only after discovering correlations may medical researchers try to explain them, but that is a secondary part of the trials.
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