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New drug to treat hay fever: How does it work?

New drug to treat hay fever: How does it work?

ITV Newsa day ago
It's the height of summer - meaning warmer weather, ice cream, and, unfortunately for many of us, hay fever.
But tens of thousands of people in England could soon benefit from a new under-the-tongue tablet that provides long-term relief for hayfever symptoms.
The drug Betula verrucosa has been recommended as an option on the NHS for people whose hayfever symptoms persist even after taking antihistamines or using nasal sprays.
Tens of thousands of allergen sufferers are set to receive the new treatment, but what is it and how does it work?
What is Betula verrucosa?
Betula verrucosa or Itulazax 12 SQ-Bet is an under-the-tongue immunotherapy tablet which has proved successful in alleviating symptoms during drug trials.
How does the treatment work?
The medication contains birch pollen extract, which works to help build your body's resilience to tree pollen.
Controlled daily amounts of the allergen will help train the body's immune system.
Trials of the drug show a significant reduction in hay fever symptoms as the body adapts to the allergens by changing how it responds over time.
Recipients of the drug will be required to take it daily for three years.
What are the symptoms of hay fever?
NHS England lists the following symptoms for hay fever:
Sneezing and coughing
A runny or blocked nose
Itchy, red or watery eyes;
Itchy throat, mouth, nose, and ears
Loss of smell
Pain around the sides of your head and your forehead
Headaches
Feeling tired
The treatment is being recommended by the National Institute for Health and Care Excellence (Nice) to those who are on the NHS and persist in using nasal sprays or taking antihistamines.
Nice estimates that around 27,000 people in England are expected to benefit from the tablet, but before having access to the medication, patients will be required to have blood tests or a skin prick to confirm they have an allergy to birch tree pollen.
According to Allergy UK, birch pollen allergy is estimated to affect around 25% of hay fever sufferers.
Amena Warner, head of clinical services at Allergy UK, said: 'Many people don't realise how awful it is having an itchy, runny nose, sneezing episodes or itchy, irritated eyes in the pollen season.
'We frequently hear from people who avoid time outdoors, keep doors and windows shut, check pollen counts, and try and minimise any exposure, which takes a significant toll on their physical and emotional wellbeing.
'Nice's recommendation is so important because it provides a genuine opportunity for people to manage the root cause of their pollen allergy, offering the chance to break free from this burden and enjoy a better quality of life.'
The NHS in England will provide the treatment within three months of Nice publishing its final guidance.
Professor Meghana Pandit, co-medical director at NHS England, welcomed the announcement.
She said: 'This innovative treatment, which will soon be rolled out on the NHS, enables patients to build up tolerance to birch tree pollen within their immune system, rather than just treating the symptoms – and we hope this will give many a new lease of life, allowing people to spend time enjoying being outside, without the discomfort allergies can bring.'
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Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. 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Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. ''It's not by choice - I think drastically dropping is far too risky for weight gain.'' The TikToker also confirmed she had been on a '' high dose '' of the jab. Social media users react The brutally honest clip sparked over 600 comments left by fellow fat jab users - many of whom opened up about their experience of '' food noise ''. ''Food noise'' is the term used to describe the near-constant stream of thoughts about eating that some people struggle to switch off. More often than not, this leads to cravings for calorie-dense, low-nutrient foods and episodes of bingeing. One wrote: ''I gained three stone in six months after I stopped it. Went to Turkey, had the [ gastric ] balloon.'' Another chimed in: ''The hunger that comes after it is awful - I've put on a stone in six weeks. Waste of money.'' A third said: ''I forgot to order my jab in time and was a literal feral person. This made me laugh so much but equally terrified to come off.'' However, others pointed out that in their eyes medications like Mounjaro aren't a permanent fix - but rather tools to help users develop healthier habits in the long run. One follower shared: ''I was absolutely starving when I came off it. ''Took so much willpower for a couple of weeks, but now I'm eating just like I was when I was on it. ''Lost three stone with Mounjaro and another two since stopping. You just have to push through until the hunger passes.'' Another said: ''Been off it three days and I'm definitely eating more. But this is where willpower comes in. I'll never be the 26 stone I was last year.'' What are the other side effects of weight loss jabs? Like any medication, weight loss jabs can have side effects. Common side effects of injections such as Ozempic include: Nausea: This is the most commonly reported side effect, especially when first starting the medication. It often decreases over time as your body adjusts. Vomiting: Can occur, often in conjunction with nausea. Diarrhea: Some people experience gastrointestinal upset. Constipation: Some individuals may also experience constipation. 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Hypoglycemia (low blood sugar): Especially if used with other medications like sulfonylureas or insulin. The reality of Mounjaro Although many have boasted about weight loss success since using Mounjaro, last year it was revealed that Scots nurse Susan McGowan, 58, died after taking low-dose injections of Mounjaro over a fortnight. A probe also found that nearly 400 people have gone to hospital after taking weight loss drugs. The common side effects include nausea, vomiting and diarrhoea, which can lead to severe dehydration. And if that wasn't bad enough, doctors say they have also seen 'life-threatening complications', including seizures, bowel obstruction and inflammation of the pancreas. Model Lottie Moss, 27, even said she had a seizure after taking high doses of Ozempic. The makers of Mounjaro, Lilly UK, said patient safety is its 'top priority'. Lilly UK stressed: 'Regulatory agencies conduct extensive independent assessments of the benefits and risks of every new medicine and Lilly is committed to continually monitoring, evaluating, and reporting safety data. 'If anyone is experiencing side effects when taking any Lilly medicine, they should talk to their doctor or other healthcare professional.'

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