
The costs of cutting canine testing
Though dogs represent less than 1 percent of animals used in science, their contributions have an outsize impact on human and pet lives. In fact, 18 Nobel laureates worked with dogs for their research.
The field of human and canine comparative oncology, in which researchers study the similarities of cancers in humans and pets, is in its infancy. Many cancers present in similar ways in dogs and humans, including bone, prostate, breast, skin, and head and neck. Research with dogs has also contributed to scientists' understanding of cardiovascular diseases. Cardiac pacemakers and stents, developed with the help of dogs, are also placed in pet dogs with heart disease. Some of the most prescribed drugs and medical devices have been developed with dogs and also benefit dogs, including lisinopril, glucometers and blood pressure monitors. And, dogs were instrumental test subjects in the early experiments that led to the discovery of insulin. Not only did this work save the lives of countless diabetic humans over the past century, but it also benefited diabetic dogs.
Scientists and laboratory animal veterinarians are committed to advancing knowledge and improving both human and animal health while upholding the highest standards of care. These professionals replace dogs with other research models whenever scientifically possible. But in many areas of research, including comparative oncology, using dogs is necessary.
When considering the ethical implications of conducting research with dogs, we should also consider the ethical implications of depriving millions of animal and human patients of treatments if a moratorium on canine research is put in place. Instead of painting a target on the backs of scientists who work with dogs to advance knowledge and treatments, we should understand and respect the necessity of their work for the sake of human and animal health.
Matthew R. Bailey, Washington
The writer is president of the Foundation for Biomedical Research.
Jane Goodall and Marc Bekoff painted a deeply troubling picture of animal testing. But the truth is more balanced: Goodall and Bekoff omitted critical context about why animal research occurs and how these animals are cared for.
The American public benefits from animal testing as many researchers seek treatments for diseases that affect both humans and pets. The decision to use dogs is not made lightly, and they are used only when no other species can answer the proposed research questions. Though most dogs that are used as research subjects must ultimately be humanely euthanized, their contributions allow scientists to gather critical data that leads to lifesaving treatments and cures. Honoring these animals means ensuring their time in research is as comfortable as possible and recognizing the lasting impact they have on future generations.
The public deserves a more realistic outlook on the challenges we face in medicine and the resources we need to address them in the safest, most effective and timeliest ways possible. The assertion that dogs are 'routinely mutilated' is not true. Studies must be necessary, ethical and conducted with the highest standards of care. Ethics committees composed of veterinarians and nonscientists assess the scientific justifications for using animals while governing the veterinary oversight needed to uphold their health and care. This includes using analgesics, anesthetics and tranquilizers whenever possible to minimize and alleviate discomfort. Researchers are committed to considering alternatives to animals such as computer modeling, cell cultures and artificial intelligence.
Welfare violations of any kind are taken seriously and warrant thorough review. But when these deplorable incidents occur, they do not represent the practices and beliefs of the broader biomedical research community, which remains committed to the people and animals in its care. Sweeping decisions to eliminate certain species in research would be irresponsible and shortsighted, as this work not only improves animal health but also holds promise for millions of Americans.
Discussions about animal research should be grounded in a complete understanding of both ethical considerations and the medical advances it allows. We owe it to the public — and to the animals — to ensure the conversation is driven by facts and realistic expectations rather than emotion and examples devoid of context.
Eliminating studies on dogs might seem like a noble goal, but we must ask: What is the cost?
Naomi Charalambakis, Washington
The writer is a neuroscientist and is director of communications and science policy at Americans for Medical Progress.
I was so grateful as I read Jane Goodall and Marc Bekoff's essay detailing the cruel treatment of dogs in some U.S. laboratories. Most of us feel immense compassion for dogs, but let's also remember that other animals used in testing are just as sentient. Many animals, however, are still used for trivial purposes, including testing household products such as oven cleaner. Let's end product testing on animals now, and work to phase out medical testing on animals in favor of more ethical methods.
Karen Dawn, Santa Barbara, California
The writer is founder and director of DawnWatch, an animal advocacy organization.
Sen. Todd Young (R-Indiana) and Matt Pottinger, in their March 25 Tuesday Opinion essay, 'R&D funding isn't a gift to academia,' were right to call for renewed federal investment in science and technology. Public funding for research and development is not a charitable gesture. It's the beating heart of U.S. technological leadership.
History proves this. The internet wasn't invented in a garage; it was born out of the Defense Department's ARPANET, a Cold War-era federal project designed to secure military communications. As Mariana Mazzucato wrote in her book 'The Entrepreneurial State,' nearly every component of the iPhone, including GPS, touch-screen and voice-recognition software, was made possible by decades of public investment.
Yet we've allowed a dangerous myth to take root: that only private markets innovate. In fact, private capital rarely steps in until the government has de-risked basic science. As Annie Jacobsen documented in her book 'The Pentagon's Brain,' the Defense Advanced Research Projects Agency invested in ideas far too speculative for the private sector.
Today, as China escalates its own R&D investment, the stakes are no longer just economic. This is about national security. Science and innovation aren't luxuries; they're important tools in our arsenal. If we want to stay ahead, we must fund bold, mission-driven science and ensure that the American people, who foot the bill, share in the rewards. That means not just commercialization but also reinvestment in public goods.
Let's stop pretending R&D is a handout. It's a strategy, and it's one we pioneered.
Joseph Frusci, New York
What happened to President Donald Trump's visionary commitment to ending the HIV/AIDS epidemic?
Hundreds of the foremost HIV scholars around the country recently received letters terminating their research grants funded by the National Institutes of Health. And NIH funding for the Adolescent Medicine Trials Network, which since 2001 has focused on preventing HIV among adolescents and saving children living with HIV, was also abruptly terminated. Many of the termination letters noted that 'so-called diversity, equity, and inclusion ('DEI') studies are often used to support unlawful discrimination on the basis of race and other protected characteristics, which harms the health of Americans. Therefore, it is the policy of NIH not to prioritize such research programs.'
The Trump administration is also considering closing the Division of HIV Prevention at the Centers for Disease Control and Prevention, which funds more than $1 billion in lifesaving programs around the country. Thousands of federal public health workers recently had their employment abruptly terminated or reassigned, many of them in the HIV field. HHS also announced its intention to remove all current members of the Presidential Advisory Council on HIV/AIDS, which provides the presidents' policy counsel about HIV issues. This is all a major reversal from Trump's 2019 State of the Union address, in which he announced a goal of ending the HIV/AIDS epidemic by 2030.
The programs that followed Trump's strategy worked. More people have access to HIV prevention and treatment than at any time in history. HIV infections are down overall, with approximately 32,000 new HIV infections in 2022, which is a 12 percent decline from 2018. Trump's plan compelled government agencies to coordinate with churches, nonprofit organizations and researchers to ensure that everyone has access to the HIV prevention and care services they need. Thanks to NIH research investments, most HIV cases can now be both prevented and treated with as little as one pill a day.
One big public health challenge is delivering lifesaving medications to the people who need them most. This is easier said than done and requires important research in real-world clinical settings. Our approach to engaging and retaining Black men in HIV prevention services has proved highly effective in pilot studies and was cited as an evidence-based best-practice intervention by the CDC in 2023. However, our larger study exploring how to scale that successful program to clinics across the United States, including in the Deep South, was terminated last month.
Many people need help accessing lifesaving medications, transportation to their appointments, and special support to pay for and adhere to their HIV medications. Thanks to Trump's 2019 plan to end the HIV epidemic, for the first time, most people who needed HIV medications could get them at no or low cost, even in rural communities. Red states benefited handsomely from this initiative, which pumped millions of dollars of resources into rural communities with high HIV rates, few physicians and few clinics. Our own research with African American clergy in the South demonstrated that this strategy really works.
Mr. President, you had an incredible plan to end the HIV epidemic. It saved lives. Please bring it back.
Amy Nunn and Philip A. Chan, Providence, Rhode Island
Amy Nunn is a professor of public health at Brown University and is chief executive officer of the Rhode Island Public Health Institute. Philip A. Chan is an associate professor of medicine and public health at Brown, chief medical officer of the Rhode Island Public Health Institute and a member of the Presidential Advisory Council on HIV/AIDS.
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Boston Globe
15 minutes ago
- Boston Globe
No meals, fainting nurses, dwindling baby formula: Starvation haunts Gaza hospitals
After months of warnings, international agencies, experts and doctors say starvation is now sweeping across Gaza amid restrictions on aid imposed by Israel for months. At least 56 Palestinians died this month of starvation in the territory, nearly half of the total of such deaths since the war began 22 months ago, according to data released Saturday by the Gaza Health Ministry. As starvation rises, medical institutions and staff, already struggling to treat war wounds and illness, are now grappling with rising cases of malnourishment. Advertisement Weak and dizzy, medics are passing out in the wards, where colleagues revive them with saline and glucose drips. Persistently short of basic tools such as antibiotics and painkillers, doctors are also running out of the special intravenous drips used to feed depleted patients. In all four hospitals, the doctors described how they are increasingly unable to save malnourished babies and are instead forced to simply manage their decline. The babies are too weak to be flooded with nutrients, which could overload their system and cause them to suffer 'refeeding syndrome,' which could kill them. Advertisement In some cases, the fluids that the doctors can safely give to the babies are not enough to prevent them from dying. 'I have seen ones that are imminently about to pass away,' said Dr. Ambereen Sleemi, an American surgeon who has been volunteering since early July at the Nasser Hospital in southern Gaza. The babies were brought to the hospital 'starving and malnourished,' Sleemi said in a phone interview Friday, 'and they haven't been able to get them back from the brink.' Dr. Nick Maynard, a British surgeon who volunteered at the same hospital until Wednesday, described the shock of seeing a skeletal infant who looked only days old, but was in fact 7 months. 'The expression 'skin and bones' doesn't do it justice,' Maynard said in a phone interview Friday. 'I saw the severity of malnutrition that I would not have thought possible in a civilized world. This is man-made starvation being used as a weapon of war and it will lead to many more deaths unless food and aid is let in immediately.' Asked for comment, COGAT, the Israeli military department that oversees aid to Gaza, said it 'continues to work in coordination with international actors to allow and facilitate the continued entry of humanitarian aid into the Gaza Strip, in accordance with international law.' Late on Saturday night, the Israeli military began to drop airborne aid over northern Gaza, and said it would pause its military activity for several hours a day in key areas to make it easier to deliver aid by land. One-third of Palestinians in Gaza are forced to go without food for days in a row, the World Food Program said recently. Of the young children and pregnant women treated at clinics run by Doctors Without Borders in Gaza, roughly one-fourth are suffering from malnutrition, the medical aid group said last week. Advertisement Doctors say that many other people have likely died from different conditions and injuries that could have been cured or healed if the victims had not been so weakened by malnourishment. Starvation is causing more mothers to suffer miscarriages or give birth prematurely, to malnourished babies with weakened immune systems and medical abnormalities. 'The result is a rise in infections, dehydration and even immune collapse in infants,' said Dr. Hani al-Faleet, a pediatric consultant at Al-Aqsa Martyrs Hospital in central Gaza. 'The immediate cause of death in some of these cases is simple: The baby doesn't get enough to eat, and neither does the mother.' 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Miami Herald
11 hours ago
- Miami Herald
Pepsi copies Coca-Cola to win back health-conscious consumers
Many Americans may not realize the importance of the gut microbiome, or the ecosystem of microbes that live in our intestines, and its impact on overall health. A 2023 Ipsos poll also revealed that many Americans have accepted to live with their digestive problems, with one in five saying they tried many things to resolve the issue, but haven't succeeded. Don't miss the move: Subscribe to TheStreet's free daily newsletter About 18% of Americans confirm they have been diagnosed with hemorrhoids, and 15% say they have been diagnosed with gastroesophageal reflux disease (GERD). How is this possible? Food plays a significant role in our gut and overall health. However, it is not the only culprit for various illnesses, because poor nutrition is often associated with other less healthy behaviors. Sugar-sweetened beverages (SSBs) are leading sources of added sugars in the American diet, and frequent consumption is associated with weight gain, Type 2 diabetes, kidney diseases, obesity, gout, a type of arthritis and more. However, more frequent consumers of sugary drinks tend to be those who don't exercise regularly, eat fast food often, smoke, don't sleep enough, and do not consume enough fruit, reports the CDC. Over the last couple of years, healthier soda alternatives have grown in popularity, due to the newer generations' focus on healthier lifestyles and mindful eating. U.S. Secretary of Health and Human Services Robert F. Kennedy Jr. recently started a major crackdown on various ingredients commonly found in food and beverages, with one of the goals being to eliminate synthetic dyes in food and drinks. Related: Scientists find massive anti-aging potential in magic mushrooms Kennedy Jr. also stressed that sodas are one of the biggest contributors to the poor health of many Americans. Under the White House's "Make America Healthy Again" initiative, pressure is mounting on soda giants to adapt their formulas. Just recently, it was announced that Coca-Cola might make a big change to its sodas- switching from high-fructose corn syrup to cane sugar. Earlier this year, Coca-Cola launched its own prebiotic soda under its juice brand Simply, and now its biggest rival, PepsiCo (PEP) , is making a similar move. More Retail: Target delights shoppers with savings event, 30% discountsUS government wants to make healthier eggs illegalPepsi issues stern message to employees after mass closures On July 21, the soda giant announced the launch of its Pepsi Prebiotic Cola with: 5 grams of cane sugar; Only 30 calories (a standard Pepsi serving contains about 150 calories);No artificial sweeteners; 3 grams of prebiotic fiber. Pepsi is launching prebiotic cola in two traditional flavors: Original Cola and Cherry Vanilla. Available in 12 oz. single cans for trial and 8-packs of 12 oz. cans, the new sodas will be available online this fall and at stores in early 2026. Pepsi Prebiotic Cola's launch comes a few months after the beverage titan announced the purchase of prebiotic soda brand Poppi for nearly $2 billion. Pepsi's move into a healthier beverages market was a way to win back customers. After all, according to a study by Harvard researchers, the number of young people who consumed at least one daily sugar-sweetened drink dropped to 61% from 80% between 2003 and 2016. Related: Target delights shoppers with savings event, 30% discounts Prebiotics are non-digestible, fermentable food ingredients that modify the composition or activity of gastrointestinal bacteria to benefit the host, according to the National Library of Medicine. Foods like cereals, breads, and snack foods have added prebiotics if you see on the food label some of the following terms: inulin, wheat dextrin, acacia gum, psyllium, polydextrose, GOS (galactooligosaccharides), FOS (fructooligosaccharides), and TOS (transgalactooligosaccharides). While prebiotic sodas can support your gut health, too much of it can cause gas, bloating, or diarrhea. Experts advise people who have gastrointestinal problems such as Crohn's or ulcerative colitis to avoid them. Samantha Nazareth, MD, board-certified gastroenterologist, told Woman's Health that prebiotic soda shouldn't replace plant-based foods like apples, garlic, artichokes, asparagus, and oats, which naturally contain gut-friendly fiber. The outlet consulted with experts to determine what health-conscious consumers should look for in prebiotic soda for the most benefits. They advised the following: Three grams of fiber per serving from ingredients like chicory root, inulin, and acacia fiberNo more than 10 grams of sugar Related: Veteran fund manager unveils eye-popping S&P 500 forecast The Arena Media Brands, LLC THESTREET is a registered trademark of TheStreet, Inc.


Forbes
16 hours ago
- Forbes
When To See ‘Shooting Stars' Tonight As Four Meteor Showers Collide
Summer's 'shooting stars' season gets underway this week with the peaks of three meteor showers. The most famous meteor shower of all, the Perseids, will peak on Aug. 12-13, but a badly timed full moon makes this week the best time to see its shooting stars. A Perseid meteor streaks across the sky above Inspiration Point early on August 12, 2016 in Bryce ... More Canyon National Park, Utah. (Photo by) Getty Images The Piscis Austrinid meteor shower will peak in the early hours of July 28, with about five meteors per hour possible, according to The following morning, July 29, will see the peaks of two more meteor showers, the Southern delta Aquariids and the alpha Capricornids. The Southern delta Aquariid meteor shower produces up to 25 shooting stars per hour, with most being rather faint. Although the alpha Capricornids number just five shooting stars per hour at their peak, they tend to include bright and colorful fireballs, according to the American Meteor Society. For all three meteor showers, the best view will likely be had about 3:00 a.m. local time in North America (all timezones), when the radiant points — the constellations of Pisces, Aquarius and Capricorn — are highest in the sky. Those constellations are all visible low on the southern horizon, so the best views will be had the farther south in North America. July 28 and 29 will be excellent nights for stargazing and looking for shooting stars if the skies are clear because the light from the crescent moon will not bleach the night sky. The Perseid meteor shower is already active, having begun on July 17 and is expected to continue until Aug. 23. On the peak night, around 50-75 meteors per hour are visible, but in 2025, that number will be significantly reduced, with only the very brightest of its shooting stars visible. That's because Aug. 9 will see the rise of a full sturgeon moon, which will remain bright and dominant in the night sky on Aug. 12-13, rising just as the peak of the Perseids gets underway. It will remain in the sky for the rest of the night. When To See The Perseid Meteor Shower In 2025 There are two periods to watch the skies in 2025 if you want to see shooting stars from the Perseid meteor shower. The first is right now before the moon reaches its first quarter phase on Aug. 1. The second is Aug. 15, when the moon will rise around midnight and a little later on subsequent nights. According to NASA, the best way to watch a meteor shower is to get out of the city to the darkest location you can, such as a Dark Sky Place. However, it's wise to check the weather forecast in advance because a clear sky is imperative. Observe somewhere with a clear view of as much of the night sky as possible, with extra layers to keep warm, as well as bug spray, snacks and drinks. Be patient, take a break every 30 minutes and avoid looking at a smartphone whose white light will kill your night vision. The Next Major Meteor Shower After the Perseids come to an end on Aug. 23, the next major meteor shower will be the Orionids. Active from Oct. 2 to Nov. 12, it will peak overnight on Oct. 22-23, one day after October's new moon. That will be perfectly dark skies, making many of the Orionids' predicted 10-20 shooting stars per hour during the peak visible to observers away from light pollution. The Orionid meteor shower is one of two annual meteor showers caused by Halley's Comet, the most famous and one of the largest comets known. The other is the Eta Aquariids meteor shower, which next peaks on May 5-6, 2026. Further Reading Forbes NASA Urges Public To Leave The City As Milky Way Appears — 15 Places To Go By Jamie Carter Forbes Get Ready For The Shortest Day Since Records Began As Earth Spins Faster By Jamie Carter Forbes NASA Spacecraft 'Touches Sun' For Final Time In Defining Moment For Humankind By Jamie Carter