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Stay safe from insect and animal bites this summer: AHS

Stay safe from insect and animal bites this summer: AHS

CTV News5 days ago
Albertans are encouraged to take precaution on outdoor summer adventures to prevent insect and animal bites and infections.
To prevent mosquito and tick bites, Alberta Health Services (AHS) suggests covering as much of your body as possible when outdoors – especially in grassy or wooded areas where ticks are commonly found.
The health authority recommends wearing a light-coloured, long-sleeved shirt, long pants and a hat as well as Health Canada-approved insect repellent.
Mosquitoes can spread West Nile virus which can affect your brain and give you flu-like symptoms.
Ticks can carry Lyme disease. AHS advises to always check for ticks when you come in from the outdoors.
Bats have been known to carry rabies in Alberta, which can impact your nervous system, including the brain, spinal cord and nerves.
AHS says to never handle a live or dead bat with bare hands as bats are likely to bite in self-defence.
If you or your child are bitten or scratched by a bat, AHS says to wash with soap and water and call Health Link at 811 or speak to a health care provider.
Household pets and indoor animals should be up-to-date on routine rabies immunizations.
It is also recommended that parents speak with their children about not touching wild animals and to tell an adult when they've been bitten or scratched.
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Health Canada expands approval of Scemblix®, making it an option for newly diagnosed and previously treated chronic myeloid leukemia (CML) patients Français
Health Canada expands approval of Scemblix®, making it an option for newly diagnosed and previously treated chronic myeloid leukemia (CML) patients Français

Cision Canada

time23 minutes ago

  • Cision Canada

Health Canada expands approval of Scemblix®, making it an option for newly diagnosed and previously treated chronic myeloid leukemia (CML) patients Français

Scemblix ® is first to show superior efficacy and a favourable safety and tolerability profile in a Phase III trial vs. all standard of care (SoC) therapies 1,2 Fifty percent of CML patients do not meet efficacy milestones (MMR) with current SoC and almost 25% discontinue or switch therapies within one year of treatments 2 Scemblix ®, a new first-line option for adults with CML, is now approved for newly diagnosed and previously treated CML MONTREAL, July 30, 2025 /CNW/ - Novartis Canada is pleased to announce that Health Canada has granted a Notice of Compliance for Scemblix ® (asciminib tablets) for adult patients with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP) who are newly diagnosed or who have previously received one or more tyrosine kinase inhibitors (TKIs). 1 In Canada, Scemblix ® was previously approved for the treatment of adult patients with Ph+ CML-CP previously treated with two or more TKIs. Newly diagnosed patients will now have access to a treatment that has shown superior efficacy versus all standard of care (SoC) therapies and a favourable safety and tolerability profile. "The approval of a new treatment option for newly diagnosed and previously treated Canadians living with CML is an important milestone," said Lisa Machado, founder, Canadian CML Network. "As a person living with CML and an advocate, I am hopeful that expanded access to this innovative treatment option will offer patients not only continued positive outcomes, but also provide the opportunity to maintain a quality of life that meets their expectations as they and their families navigate the complexities of CML management." CML that is diagnosed in the chronic phase has a more favourable prognosis than CML that is diagnosed in the accelerated or blast phase. Although the Ph chromosome is present in everyone with CML, in rare cases it can't be found during testing. In general, Ph+ CML has a more favourable prognosis than Ph- CML. 3 While TKIs have transformed CML into a chronic disease, efficacy, safety and tolerability challenges continue to hinder long-term treatment success for many patients. Many patients do not meet molecular response goals, and many discontinue or change treatment due to intolerance. 4,5,6 "The approval of asciminib represents a significant step forward, expanding treatment options for CML patients," said Dr. Dennis Kim, Professor of Medicine, Princess Margaret Cancer Centre. "Having a diverse range of therapies available allows care teams to keep the unique needs of the patient at the centre of treatment plans, optimizing outcomes. The ability to prescribe asciminib to newly diagnosed and previously treated patients offers a promising new pathway in our efforts to manage this complex disease effectively and safely." "We are proud that Health Canada has expanded its approval of Scemblix ®, making it a new option for all Canadians with chronic myeloid leukemia, whether they are newly diagnosed or have been previously treated," said Mark Vineis, Country President, Novartis Canada. "This approval means patients and their physicians now have more choices when deciding on the best course of treatment, offering renewed hope for individuals living with CML, their families, and the healthcare teams dedicated to their care." The clinical effectiveness, safety and cost-effectiveness of Scemblix ® is currently under review by Canada's Drug Agency (CDA) and Institut National d'Excellence en Santé et Services Sociaux (INESSS). Novartis looks forward to communicating their recommendations with the CML community, when available. About Chronic Myeloid Leukemia (CML) Chronic myeloid leukemia (CML) is a type of cancer that develops in the blood-forming cells of the bone marrow. In 95% of patients with CML, a genetic mutation produces an abnormal chromosome in bone marrow stem cells known as the Philadelphia chromosome ("Ph chromosome"). When the Ph chromosome is present, CML is classified as Philadelphia chromosome-positive (Ph+). 7 The Ph chromosome produces the BCR-ABL1 protein, which causes bone marrow to make too many abnormal white blood cells. These cells overcrowd healthy blood cells, which can be fatal if untreated. 7 CML has three stages: chronic, accelerated, and blast phases. Most patients are diagnosed in the chronic phase, and with proper treatment, can often stay in this early stage without advancing further. 7 According to the most recently available data, 665 Canadians were diagnosed with CML in 2019 and 140 Canadians died from CML in 2022. 8 About Scemblix ® (asciminib tablets) Scemblix ® is the first CML treatment that works by Specifically Targeting the ABL Myristoyl Pocket (referred to as a STAMP inhibitor in scientific literature). 9,10 The current approved CML treatments are TKIs that target the adenosine triphosphate (ATP)-binding site (ATP-competitive). 10 About the ASC4FIRST Trial The approval of Scemblix ® is based on results from the ongoing Phase III ASC4FIRST trial in patients newly diagnosed with Ph+ CML-CP. 1 Data has shown: Nearly 20% more patients treated with Scemblix ® achieved MMR versus investigator-selected (IS) SoC TKIs (imatinib, nilotinib, dasatinib and bosutinib) (68% vs. 49%, p < 0.001) and nearly 30% more patients achieved MMR versus imatinib alone (69% vs. 40%, p < 0.001) at week 48. 1,2 Scemblix ® is the first CML treatment to show superior efficacy along with a favourable safety and tolerability profile verus imatinib and second generation TKIs. 1,2 In newly diagnosed Ph+ CML-CP patients, the most common adverse reaction (≥ 20%) was musculoskeletal pain. Serious adverse events occurred in 11% of patients who received Scemblix ®. Serious adverse reactions in ≥ 1% included pancreatitis (1%). 1, 2 About Novartis Novartis is a focused innovative medicines company. Every day, we work to reimagine medicine to improve and extend people's lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide. In Canada, Novartis Pharmaceuticals Canada Inc. employs approximately 600 people to serve the evolving needs of patients and the healthcare system and invests over $30 million in R&D yearly in the country. For more information visit SCEMBLIX ® is a registered trademark. SOURCE Novartis Pharmaceuticals Canada Inc.

Kids under 12 in Alberta face months-long gap in COVID vaccine availability
Kids under 12 in Alberta face months-long gap in COVID vaccine availability

CBC

time24 minutes ago

  • CBC

Kids under 12 in Alberta face months-long gap in COVID vaccine availability

Shuhiba Mohammad recently took her daughter for her routine childhood immunizations at age 1, and was frustrated when she was told she'd have to book a separate appointment to get a COVID vaccine. Then, when she called Alberta Health Service's 811 phone number to book an appointment, she learned her child couldn't get a COVID shot, at all. "I was on the phone for about 45 minutes and somebody got back to me that the Moderna vaccine — that was the COVID vaccine given to children under the age of 12 — was expired as of June 17 ... and so there is no opportunity to vaccinate a child under 12 for COVID until the fall," she said. "So we're kind of in a little bit of a limbo, where she's going to have no immunity to COVID and we've just started daycare." Mohammad says she would have appreciated some kind of heads up or communication about this from public health officials, but actually received the opposite when she brought her daughter to her six-month routine immunization appointment. "They had said that we will deal with the COVID vaccines at a year of age," Mohammed said. "But now that I went and I looked it up and I dug into it a little bit deeper, I could have gotten her a vaccine at six months, but public health had told me a year." The AHS vaccine-booking website now informs visitors: "COVID-19 vaccine for individuals 6 months up to and including 11 years of age expired June 17, 2025. After this date, COVID-19 vaccine will only be available for eligible individuals 12 years of age and older." But that warning did not appear in an earlier version of the website, captured on June 14 by the Wayback Machine. Adult vaccines about to be pulled, too An AHS spokesperson declined to answer questions about the vaccine availability, referring them instead to the province's newly created Ministry of Primary and Preventative Health Services, headed up by former health minister Adriana LaGrange. An official with the ministry told CBC News in an email the Moderna COVID-19 vaccine "is currently unavailable across Canada, as all remaining doses have expired" and new doses for children aged six months and older are expected "in the fall." Adults, too, will also soon be ineligible to receive the current batch of COVID shots. "The KP.2 COVID-19 vaccine will no longer be administered in Alberta after July 31, as the province prepares to introduce a new formulation this fall," the official said. "Most remaining KP.2 doses are nearing expiry, and removing them now helps ensure a smooth transition to the new prefilled syringe formulation, which also requires different storage and planning." Craig Jenne, a professor in the department of microbiology, immunology and infectious diseases at the University of Calgary, said it's "frustrating" that children, in particular, will have a months-long gap in vaccine availability. "We have to appreciate that maybe, at a population level, the kids are less at risk of severe COVID, but we do know that the youngest ones are at risk of intensive care unit admission," he said. "So, the fact that this is a Health Canada-approved vaccine, we know it works, we know it's safe, but it's simply not available is really frustrating from the public health level." 'We've got to jump through multiple hoops' Jenne said from a public health perspective, the goal is generally to make vaccines as easily available as possible. "What we've seen with COVID is the exact opposite," he said. He worries about the provincial government's plan to starting charging Albertans a fee for COVID vaccines, once new doses arrive in the fall, and to require people to pre-register to receive them at specialized immunization clinics, because the province will no longer make them available at pharmacies. "So this is now a vaccine that we've got to jump through multiple hoops for — including a significant cost barrier to some Albertans — and there's no doubt that this will drive down uptake and leave a percentage of Albertans who may otherwise want to be protected unable to access the vaccine," Jenne said. In announcing the plans to reduce availability and start charging for the vaccine, the government of Alberta cited COVID immunization advice from the United States. "Recently, the Federal Drug Administration in the United States stopped recommending routine COVID-19 vaccines for pregnant women and healthy children," the province said in a June 13 press release. That change had been announced in May by U.S. Health and Human Services Secretary Robert F. Kennedy Jr. and runs contrary to the latest vaccine guidance in Canada. Starting Aug. 11, the province plans to launch a new "pre-order tool" through its vaccine-booking system where Albertans can "express interest" in receiving both the COVID and influenza vaccines. "Those who pre-order will receive a reminder by text or email prompting them to book their appointment in early October. Pre-ordering is being used to help plan for vaccine needs and reduce potential waste," the ministry official said. "Due to recent changes to the federal COVID-19 vaccine procurement process, provinces and territories are now responsible for purchasing COVID-19 vaccines for residents. Alberta's government remains committed to ensuring Albertans at highest risk of severe outcomes from COVID-19 have access to immunizations." Most Albertans will have to pay for the COVID shot in the fall but the price has not yet been announced. Flu vaccines will remain free, the ministry official said.

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