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The unlikely group 'destined' to be struck by Alzheimer's disease as early as 40

The unlikely group 'destined' to be struck by Alzheimer's disease as early as 40

Daily Mail​17 hours ago
Alzheimer's disease is largely seen as one of old age.
The most common form of memory-robbing dementia, Alzheimer's affects nearly 7 million Americans, most of whom are over the age of 65.
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James Van Der Beek colon cancer battle: 'I dismissed key symptom... don't make the same mistake'
James Van Der Beek colon cancer battle: 'I dismissed key symptom... don't make the same mistake'

Daily Mail​

time2 hours ago

  • Daily Mail​

James Van Der Beek colon cancer battle: 'I dismissed key symptom... don't make the same mistake'

Dawson's Creek heart-throb James Van Der Beek has told how he dismissed a tell-tale sign of his colon cancer because it 'didn't feel like a real symptom'. The actor, who lives in Texas, revealed in November that he had been diagnosed with colorectal cancer in August 2023, aged just 46. In a fresh interview this week, the now 48-year-old said a change in his bowel movements, a common sign of the condition, was the first indication something was amiss. Yet, he blamed it on coffee and cut out the hot drink to resolve the issue by itself. It was only when the symptom persisted that he got a colonoscopy. Test results soon revealed it was stage three cancer, meaning the disease had spread to his lymph nodes. The disturbing rise of colorectal cancer—also known as colon or bowel cancer—in under 50s has baffled doctors around the globe. The disease—which also claimed the life of Dame Deborah James at the age of 40—has surged by 50 per cent this age-group over the past three decades. Now, James is calling on people to recognise the little-known signs of the cancer and not to give up if they think something isn't right with their body. He told Business Insider: 'It didn't feel like a real symptom of anything. It wasn't anything that made me rush off to go get screened.' Prior to his diagnosis, he was invested in maintaining peak health, he added. 'I was doing everything, I was doing sauna, cold plunge, weightlifting, Pilates. I would dance and also do football training.' He balanced strength training with cardio and ate mostly organic food, 'doing all the biohacking things' to stay fit, he added. 'It [the diagnosis] really took a while to set in. The reality still sets in stages, there are so many unknowns.' But raising awareness of the condition has given him a sense of purpose throughout his ongoing treatment. 'I've learned a lot,' he added. 'If I can save anyone from having to go through this, that's magic.' There are around 44,000 cases of bowel cancer every year in the UK and 142,000 in the US, making it the fourth most common cancer in both countries. Symptoms often include changes in bowel movements such as consistent and new diarrhoea or constipation, needing or feeling the need to poo more or less frequently and blood in the stool. Stomach pain, a lump in the stomach, bloating, unexpected weight-loss and fatigue are among other signs. Anyone experiencing these symptoms should contact their GP for advice. Although the vast majority of bowel cancer diagnoses affect those aged over 50, rates in older age-groups has either declined or held stable while diagnoses in younger adults have risen by 50 per cent over the last 30 years. Cancer Research UK estimates that over half (54 per cent) of bowel cancer cases in the UK are preventable. Doctors have suggested obesity, antibiotic over-use, mobile phone radiation and even invisible particles of plastic in drinking water are potential triggers. However a growing number of experts are also pointing ultra-processed foods as a cause. Earlier this year James opened up again about his cancer journey as he marked his 48th birthday. In a video posted on Instagram, he told his 1.6 million followers the last year, 'has been the hardest of my life'. Labeling the clip 'What Cancer Taught Me,' he described how coming 'nose to nose with Death,' had helped him redefine who he is. 'When I was younger, I used to define myself as an actor, which was never all that fulfilling, and then I became a husband and it was much better and then I became a father and that was the ultimate,' he said. Being away from his family for treatment and living alone in an apartment had forced him to 'look my own mortality in the eye.' 'All of those definitions that I cared so deeply about were stripped from me,' the dad of six also said.

‘Never ever go on Mounjaro' says influencer who lost 6lbs in 2 days but was left ‘dying & crawling on the floor
‘Never ever go on Mounjaro' says influencer who lost 6lbs in 2 days but was left ‘dying & crawling on the floor

The Sun

time3 hours ago

  • The Sun

‘Never ever go on Mounjaro' says influencer who lost 6lbs in 2 days but was left ‘dying & crawling on the floor

INFLUENCER and YouTube star Tana Mongeau has issued a dramatic warning to fans after trying the weight loss jab Mounjaro. The US star, 26, says it left her crawling on the floor and feeling like she was "dying". 5 5 5 Tana Mongeau, who boasts over 5 million followers, opened up about her experience with the controversial injection on her podcast Cancelled with Tana Mongeau and Brooke Schofield on YouTube. Speaking to co-host Brooke Schofield, Tana didn't hold back about how badly the medication affected her, despite shedding 6lbs in just two days. 'So I shot up Mounjaro,' she began. 'And this is the biggest public service announcement to the whole wide world to never, ever, ever do it. I have been dying this week. Like, dying. Like, crawling on the floor.' The reality star, who's known for her chaotic storytelling and viral moments, said she was so nauseous she had to take Zofran – a prescription anti-sickness medication – every day for breakfast just to cope. She claims the fat jab left her "gripping the walls". Tana added: 'I don't wanna get into the bowels. But they are not regular. They're not okay. Or too regular.' The 26-year-old claimed she was sleeping for more than 12 hours at a time and even joked: 'I think I have osteoporosis now because of it.' She admitted that the jab worked fast and she felt 'tiny' after dropping the weight almost instantly and said she was happily eating protein. But the side effects weren't worth it. 'I am done with it,' she said. 'I don't think I'll ever do it again.' Mounjaro is a diabetes drug that's recently gained popularity in Hollywood and on TikTok as an off-label weight loss injection. It works by mimicking a hormone that helps regulate appetite and blood sugar levels but it's known to cause strong gastrointestinal side effects, including nausea, vomiting, diarrhoea and constipation. Tana's extreme reaction, including severe nausea, exhaustion, disrupted digestion and prolonged sleep, is likely due to how the drug slows down digestion and suppresses appetite. Some users also report symptoms like dehydration, cramping and dizziness as the body adjusts. While many have hailed Mounjaro as a 'miracle' fat-loss fix, experts have warned it's not for everyone, especially if taken without medical supervision. Tana's honest confession struck a chord with fans, with many praising her for calling out the risks and opening up about the darker side of so-called 'quick fixes.' One fan commented online: "this is so scary". Another added: "Wow, I had no idea the effects were that bad". The star doesn't deny the fat jab's results. As she bluntly put it: 'Anything that's a quick fix, obviously, it works well. But I should not have done that". She's not the only user reporting odd side effects. Kelly, from the UK, took to social media to share how her journey on the weight loss jab was going. Kelly is currently on 10mg of Mounjaro a week, but she said it wasn't working as it was supposed to. She said the drug had totally changed her taste buds making it difficult for her to eat. Others have warned of severe hair loss. Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. 5 5

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