Rich's Ice Cream bars recalled in 23 states over listeria risk
The affected products include Chocolate Crunch Cake Bars, Strawberry Shortcake Bars, and several other flavors, identified by specific lot numbers from 24351 to 25156.
These ice cream bars were distributed and sold in 23 US states, including Florida, California, and New York, as well as in Nassau, Bahamas.
The recall is classified as Class II, indicating that use of or exposure to the product is not likely to cause adverse health consequences, but consumers are urged to dispose of the items.
Listeria infection, which can lead to invasive and intestinal illness, is the third leading cause of death from foodborne illness in the United States.
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Daily Mail
5 hours ago
- Daily Mail
I tried the mysterious blue substance loved by RFK Jr to cure my jet lag... I was shocked by what happened to my body
There's no pill or instant fix for jet lag. But with more than 20 hours of flight time from New York to Australia on my horizon, I was eager to unearth any solution in a bid to make the most of my 10-day trip. Friends had suggested everything from the prescription anti-anxiety drug Xanax (alprazolam) to melatonin supplements to pack in some sleep. but then another recommendation from a travel pro piqued my interest: Methylene blue. Methylene blue, which is a cobalt blue-hued synthetic dye, has a long history of being used as treatment for ailments, including for malaria and a rare blood disorder called methemoglobinemia. But in recent years, an increasing number of people believe it may offer various other health benefits, particularly for cognitive function and potentially as an anti-aging agent. Research even suggests that it can kill cancer cells under specific conditions. And In February, footage emerged of Health Secretary Robert F Kennedy Jr, 71, on a plane using a pipette to add droplets of a blue liquid to his drink. It is unclear where and when the video was filmed and the footage doesn't show him consuming the concoction. But the clip spread widely on social media, leading to speculation about what it could be. Some medical experts said the blue liquid was likely methylene blue, although he has never commented on what it was. Mel Gibson and Joe Rogan are also among the fans of methylene blue. Brandon Dawson, co-founder and CEO of 10X Health, an individualized wellness company, told me he is also a big advocate of methylene blue to mitigate the tiring effects of long travel journeys. Dawson says he swears by the supplement and he never suffers from jet lag, despite hopping on multiple flights a week around the world. Following his revelation, I stocked up on 10X's methylene blue drops. A 30ml bottle costs $37, with this amount set to last a month if you take it on a daily basis. Dr Johnny Parvani - who runs 10X's IV arm of the business, offering patients infusions of vitamins, minerals, and electrolytes to boost their health - recommended that I start taking methylene blue one day before travel and then throughout the journey and during the trip. Explaining the benefits, he told me: 'This supplement can facilitate the role of oxygen in generating energy in high altitude environments such as with air travel. 'The supplement should help you remain more focused and energized and help you adjust to the new time zone quicker.' Currently methylene blue is not FDA-approved for jet lag, only for methemoglobinemia, and there have been no clinical trials or studies specifically evaluating the effectiveness of it for long-haul air travel. Research is limited, but a 1995 study found the substance can increase oxygen levels in the blood and improve the blood's ability to carry oxygen throughout the body. Some experts argue that, by increasing the amount of oxygen in the blood, methylene blue can improve the health of the mitochondria – the powerhouse of cells in the human body. In doing so, they argue, this can slow down aging or even prevent cancer – which occurs when cells malfunction and mutate. However, perhaps the most excitement is over the potential use of methylene blue for preventing dementia – the incurable degenerative brain disease that affects more than 7million Americans. The exact cause of dementia is unknown, but one theory is that it is triggered by malfunctioning mitochondria in the brain. In 2020, a Chinese paper published in the medical journal Translation Neurodegeneration suggested that methylene blue be considered as a possible preventative treatment for dementia. Another proposed use for the blue dye is treating the mental health disorders depression and bipolar. By improving the function of the mitochondria, supporters argue, this should also boost levels of serotonin, the 'happy hormone,' in the brain. In fact, studies do show that methylene blue can increase serotonin levels. Some research even suggests it can alleviate mental health issues. But back to me - I decided to trial the concoction for myself. In liquid form, you take methylene blue by using a dropper to add it to water. Dr Parvani advised me to drink it through a straw as the liquid can stain your teeth and he also warned me that it could turn my urine blue. Before my trip, I discovered that methylene blue is actually illegal if it is imported into Australia without a prescription as it is a classified as a Schedule 4 substance. After learning this, I hatched a plan to ditch it while changing planes in California and to pre-mix a drink for the 15-hour flight from Los Angeles to Sydney. Dr Parvani said I should still get the benefits of methylene blue despite not continuing to take it during my trip. The label on 10X's methylene blue drops instructs you to start with five drops diluted in water, with this increasing by five drops weekly until you reach a full pipette (20 drops). Following Dr Parvani's orders, I started by taking the supplement the morning before I traveled. When you first put it in water, the color is barely visible but as it dilutes, it gets increasingly blue. The mesmerizing color change filled me with vague concern as to what it could do to my internal organs. The 10X product says it has a 'pina colada' flavor but I didn't taste anything vaguely fruity while sipping it. To my relief, I also didn't experience any signs of blue pee. At the airport, I took another dose of methylene blue before the next flight on my journey. I'm not sure if it was a placebo effect or the methylene blue working its magic, but I did feel strangely energized and alert the day I traveled. I also went on to have some of the best sleep I had ever had on a plane despite being cooped up in economy. However, there were a couple of side effects I believe may have been from the substance. Firstly, I appeared to lose my sense of taste, and then as I was sleeping, I suffered from pins and needles in my legs and arms. A quick Google, showed that these can be side effects of methylene blue. Other common complaints include dizziness, a fast heartbeat, a headache, shivering and a sore throat. Luckily, I didn't experience any other discomfort while taking the supplement and when I landed in Australia, I found the benefits outweighed not being able to taste my plane pasta dinners and having a dead leg mid-flight. On landing into Sydney at around 7am after more than 24 hours of travel, I felt surprisingly perky. In fact, I managed to stay awake the whole day before rolling into bed at 10pm. The next day, I ran three miles in the morning and embarked on a 12-mile hike in the afternoon. Maybe RFK Jr is on to something. Next time I travel, methylene blue is something I would consider using but if losing my taste is a consequence, it's not something I'd take on a daily basis. Experts say some people are more sensitive to the substance than others, and my friend who took a dose from my bottle returned from the bathroom an hour later exclaiming 'my pee is blue!'
Daily Mail
8 hours ago
- Daily Mail
Revealed: The women who look 10 years younger WITHOUT Botox and credit non-invasive procedures for their incredible transformations
Forget Botox and surgeries, these days many women are opting for non-invasive procedures - and the results are no less incredible. With an increased awareness of the benefits of skincare thanks to social media, people appear to be wanting more 'natural' and less 'over surgery-ed' looks, in a phenomenon that has been dubbed 'Notox'. Incredible before and after pictures taken by skincare experts at CACI International - who describe themselves as pioneers of the 'non-surgical face lift' - show the epic results that they claim can be achieved through these methods. According to the experts, targeted treatments can improve the appearance of jowls and help aid the symptoms of Bell's Palsy. The transformation pictures appear to show tighter and more sculpted jawlines, as well as glowing and brighter skin. For those with Bell's Palsy, the after pictures seem to signify a return of symmetry in the face. Lena Bratschi, the founder of The Carasoin Day Spa in West Hollywood, boasts celebrity clients including Michelle Williams, Elizabeth Debicki, Caitriona Balfe and Sarah Paulson. She said: 'Not only is there a shift towards more non-surgical options but it's something we've seen increasing in popularity steadily over the past few years. More and more women seem to be opting for 'Notox' - or, non-surgical procedures. Pictured: The before and after of a jowl lift at Lindsey Anne Beauty and Cosmetics in Penkridge, without going under the knife 'It's a clear push back against the 'over surgery-ed' look and while people still want to look their best, they don't want to look like they've clearly had work done. 'Because of this, I think people want to explore other options that don't have the downtime or risk of complications, so they're opting for non-invasive procedures.' Lisa Franklin, a leading skin expert at CACI's Clinic Privé in Knightsbridge, told MailOnline that the advantages of opting for non-surgical solutions can include 'delivering visible skin rejuvenation without the need for invasive procedures, downtime or recovery', unlike surgical options 'which can be drastic and carry risks'. She said: 'It's a non-surgical, pain-free approach that works in harmony with your skin's natural processes - stimulating collagen, improving muscle tone, and restoring radiance.' The experts liken the procedures to a 'gym routine' as they tend to build it up over time. JOWL LIFT Jowls are the sagging and loose skin below the jawline that often develops with age, as the skin becomes thinner and looses elasticity - commonly for those in their late 30s and early 40s. While many people have traditionally opted for surgical facelifts, non-surgical 'jowl lifts' have, in some cases, also proven effective. Incredible before and after pictures of CACI's non-surgical jowl lifts seem to have resulted in sharpened and more chiselled jawlines - all without going under the knife. The procedures target muscle laxity around the jawline and can improve the appearance of sagging jowls by lifting and firming the muscles. The treatments may also use LED light therapy and microcurrents to aid in boosting the skin. Richard, 37, from Staffordshire, is a cardiac nurse who said he had 'always been bothered' by his jowls. He said: 'This is something that has always bothered me. Growing up I never liked my jowls and as I have aged, I dislike them even more.' Richard completed a course of CACI treatments at The Chase in Staffordshire in 2023, continuing to have them monthly. He added: 'Although I know there are invasive treatments I could use, I find it difficult to trust others to inject my face as I do this for a living. I much prefer to have non-invasive treatments, and I love the time out for myself. 'I now feel I can't go without it, and I always ensure I pre-book my appointments. I look forward to them and always feel like my face has had a work-out straight after my facial.' To prevent jowls forming, cutting out smoking, limiting exposure to the sun and screen time can also help, according to Healthline. FACIAL TONING One of CACI's statement treatments is facial toning - which takes a variety of forms. At a basic level, it is the lifting and toning facial muscles while reducing fine lines and wrinkles. Methods can include microcurrent gua sha, which combines modern technology with traditional techniques. This promotes lymphatic drainage, enhances circulation, and reduces puffiness. At the same time, the presence of microcurrents works to contour and sculpt the face for a more defined and youthful experience. Non-surgical facial toning uses skin exfoliation techniques to brighten and smooth the skin, toning and lifting the face and firming the neck. In addition, treatments may include LED light therapy, hands-on therapy and energising masks, stimulating collagen and elastin. For men, deep exfoliation and cleansing can be used to tackle razor bumps and ingrown hairs from shaving. Elaine Hendry, 57, from Scotland said she began getting toning facials around 15 years ago, when she was 42. She said: 'I was starting to see fine lines appearing and felt my skin was very dull. 'I didn't want to go down the road of Botox and fillers as I wanted a more natural way forward. Plus, I'm a hairdresser and I saw some clients with Botox that had gone wrong, and they wished they hadn't got it done. 'I started noticing how clear my skin was, and my eyebrows were higher. People were starting to tell me how well I looked.' Now, fifteen years later, Elaine, who is a client of Brownz Beauty in Largs, says: 'My jawline is toned, and my lines are minimal. What I love about it is that I have managed to avoid Botox and fillers and I still look like me.' Krystyna Gibbons, 65, from Lincolnshire says she's 'never' taken for her real age, as people usually assume she's 10 years younger. Krystyna, who visits Enhance Beauty in Grantham, says she's been having non-surgical facials for 16 years and credits it with changing her life. 'From my first facial I was hooked,' she said. 'My appearance was crucial as I worked with high-end blue-chip clients and organisations and attended events gala dinner awards ceremonies. 'I am always being complemented on my glowy skin. I can honestly say I will never give it up. As well as being a great facial it is also my "me time" once a month to relax and shut the rest of the world out - a true luxury experience.' BELL'S PALSY Bell's Palsy is a sudden form of facial paralysis that usually affects one side of the face. According to the NHS website, effective treatments can include steroids and most people get better within six months. If symptoms do not improve, those with the condition can return to their GP. Experts at CACI also recommend non-surgical procedures to help with symptoms. Martin Scott decided to visit the Float Spa in East Sussex after discovering CACI was originally designed to treat Bell's Palsy. He said: 'I found Bell's palsy to be very tough mentally – not being able to talk, eat or drink properly, and having to tape my eye down each night. 'I wanted to start it immediately.' As the whole of the right side of Martin's face was paralysed, he couldn't close his eye or smile on that side. Martin's skin therapist Lorraine recalled: 'It was extremely difficult and distressing for him as he was slurring his speech, and dribbling. 'He also had to tape his eye down as he couldn't close it to sleep. I needed to focus on the whole of his right side particularly his mouth and eye area.' For Martin's treatment, Lorraine explored the use of probes to hold his muscles for a set period of time, using microcurrent power and allowing space in between treatments to allow the muscles to rest. A day or so after his initial treatment, Martin saw an encouraging sign - slight eyebrow movement. He then started to see progress after each treatment, eventually regaining full use of his facial muscles and recovered symmetricity. Lorraine says: 'I was extremely pleased with the result. After only four treatments, he regained full use of all his muscles and his face was symmetrical. After the fourth treatment (over 10 days) he was able to fully close his eye at night.' Martin added: 'The results were nothing short of miraculous for me. I was in and out of Bell's palsy in 24 days. Once treatment was over, I felt fantastic. I basically had my face and my life back.' Another client, Ken, 71, came to the Lindsey Anne Beauty and Cosmetics Clinic in Penkridge with his third episode of Bell's Palsy. Lindsey said: 'He had been down many different avenues to find the right treatment - physio, medicines - but nothing worked.' He began treatments twice a week, starting gently as he had severe sensitivity. Lindsey began began doing jowl lift movements on the one side of his face where his Bell's palsy occurred. She could then start to put more pressure and time behind each movements. She later began jowl movements to lift both sides of his face, before moving onto eye revive treatments to improve facial symmetry. Ken said he was initially 'sceptical' as nothing previously had worked for him, but said it had changed his life, giving him the confidence to go out and start to re-live again. If somebody's face is drooping on one side, they cannot lift up their arms and keep them there, or they have difficulty speaking, it could be the signs of a stroke rather than Bell's Palsy and 999 should be called as soon as possible.
Daily Mail
15 hours ago
- Daily Mail
Scientists discover two drugs already approved by the FDA can reverse Alzheimer's
Two drugs already approved by the FDA for cancer treatment may hold the key to reversing Alzheimer's disease in patients, experts say. Researchers from the University of California, San Francisco (UCSF) believe that letrozole, a hormone-based breast cancer drug, and irinotecan, a lung and colon cancer chemotherapy medication, can help reverse brain damage caused by the incurable neurodegenerative disease. In an animal study, the UCSF experts found that both cancer drugs were seen to reduce brain degeneration in mice and even improve their memory and learning capacity. Alzheimer's disease is one of the most common forms of dementia and mostly affects adults over the age of 65. About 7million Americans live with the condition and over 100,00 die from it annually. The disease is believed to be caused by the development of toxic amyloid proteins and/or tau proteins in the brain, which can accumulate and damage cells responsible for memory and learning. Amyloid protein molecules stick together in brain cells, forming clumps called plaques. While tau proteins twist together in fiber-like strands called tangles. As of now, there is no cure for AD and only two FDA-approved therapies, Lecanemab (Leqembi) and Donanemab (Kisunla), are available for early-stage Alzheimer's treatment. However, because letrozole and irinotecan are already approved for other treatments, this could fast-track clinical trials and the potential approval for use in Alzheimer's patients. Co-senior author Dr Marina Sirota, a professor at UCSF, said: 'Alzheimer's disease comes with complex changes to the brain, which has made it tough to study and treat, but our computational tools opened up the possibility of tackling the complexity directly. 'We're excited that our computational approach led us to a potential combination therapy for Alzheimer's based on existing FDA-approved medications.' In Alzheimer's patients, the plaques and tangles block the ability of the brain's neurons to send electrical and chemical signals back and forth. Over time, this disruption causes permanent damage in the brain that leads to Alzheimer's and dementia, causing patients to lose their ability to speak, care for themselves and interact with the world around them. While the exact mechanisms of how the Alzheimer's-related brain damage begins are still under investigation, age and genetics are known risk factors. Experts also believe that lifestyle factors such as physical inactivity and high blood pressure can also contribute to the development of Alzheimer's. Despite rigorous preclinical and clinical research efforts, drug development for dementia faces significant challenges, with a 98 percent failure rate in recent decades. Neuroscientist Dr Yadong Huang, co-author of the study and professor of neurology at UCSF, explained: 'Alzheimer's is likely the result of numerous alterations in many genes and proteins that, together, disrupt brain health. 'This makes it very challenging for drug development – which traditionally produces one drug for a single gene or protein that drives disease.' However, researchers at USCF believe their discovery can help reduce or reverse the cognitive decline caused by the disease. First, the team looked at how dementia changes gene expression in the brain. Then, they scoured a database of over 1,300 drugs, including antipsychotics, antibiotics, antifungals and chemotherapy drugs, to determine which, if any, reversed any of these gene expressions. If any existing drugs were found to be effective, they could be repurposed to treat the condition in a reduced the time in which the drugs could be made available to patients. During their search, the team specifically looked for drugs that would target the harmful Alzheimer's-related changes in neurons and in brain cells called glia that are responsible for supporting the nervous system. Then, the researchers analyzed millions of digital medical records to find patients who took some of these drugs as part of cancer treatments and their likelihood of developing Alzheimer's. Ultimately, they identified letrozole and irinotecan as the best candidates to lower Alzheimer's risk in patients. By combining the two drugs together, the researchers were able to target different types of brain cells affected by the disease. They noted that letorozole could counter the effect of Alzheimer's on neurons and irinotecan helped reverse damage on the glia cells. When the combination was tested on mice, the scientists saw that the harmful clumps of tau protein were reduced significantly and the mice showed improvements in learning and memory tasks. The study authors noted that it remains unclear how the cancer drugs are able to reverse the damage. However, they theorized that it was possible that letrozole blocks the production of estrogen, a hormone that controls the working of a large number of genes, which therefore reduces the genetic risk factor of developing Alzheimer's. Additionally, they believe that irinotecan may also block inflammation in the brain by preventing the rapid reproduction and DNA damage of glial cells. As this was an animal study, the researchers hope to test the drugs in a clinical trial with human Alzheimer's patients. Dr Huang said of the results: 'Developing a new drug can take hundreds of millions, or even billions, of dollars, on average take more than 10 years. For this repurposed drug, usually it just takes two or three years, and then you can go to the clinical trial and the cost is much, much lower. 'We still haven't generated or produced any very effective drugs that can really slow dramatically the cognitive decline.' However, despite their groundbreaking discovery, risks continue as letrozole is known to cause hot flashes in patients while irinotecan can cause severe diarrhea. Both drugs can also lead to nausea and vomiting. Dr Sirota said: 'These drugs have huge side effects, so you need to always balance and figure out whether those types of side effects would be amenable to somebody with Alzheimer's. It's not that it's a slam dunk.'
