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30+ Prime Day K-Beauty Deals You Should Know About in 2025

30+ Prime Day K-Beauty Deals You Should Know About in 2025

Vogue08-07-2025
Prime Day Korean Cleanser Deals
The best Korean face washes typically focus on soothing, gentle ingredients. Whether you're opting for a cleansing oil to melt away makeup and SPF, or a hydrating foaming cleanser—either make a great first step in any routine. Though, ideally, you'll do both as part of the Korean cleansing method, a.k.a the lauded double cleanse. Banilla co. offers a cleansing balm fueled by fermented thermal water and berry extracts (with 10k and counting glowing reviews), while Anua's cleansing oil unclogs pores with ease using anti-acneic ingredients like turmeric and heartleaf extract. On the face wash front, CosRx and Mixsoon both offer low pH face washes that provide a gentle yet an effectiv cleanse optimized for sensitive skin.
Prime Day Korean Toner Deals
While the norm is that a toner should be an astringent that removes grime and dirt while balancing skin's pH, the best Korean toners also flood it with hydration after cleansing with a face wash. In the past, 'toners were used to ensure there is no trace of makeup left after you wash your face and also to balance your skin's pH—because in the old days, most of the face washes were soap-based and could be alkaline,' cosmetic chemist Ginger King previously told Vogue. For a soothing toner, you can't go wrong with Anua, Haruharu Wonder, or Beauty of Joseon (extra points for this pick, if you prefer a milky toner). Meanwhile, Some By Mi opts for a liquid exfoliant toner—shop any four of these K-beauty favorites on sale, below.
Prime Day Korean Targeted Treatment Deals
A thoughtful skin-care routine isn't complete without targeted treatments designed to address specific concerns—think potent serums and exfoliants that do the heavy lifting. For congested or breakout-prone skin, exfoliating pads are a game-changer. Medicube's version blends salicylic acid and willow bark extract to unclog pores, while hyaluronic acid and cica work in tandem to calm and hydrate. And no conversation about K-Beauty would be complete without mentioning spicule serums, the innovative Korean formulas infused with microscopic, needle-like structures derived from sea sponges. Beloved for their exfoliating and microneedling-like effects, they've gained serious traction—VT's iteration, in particular, has emerged as a cult-favorite. Another K-beauty staple? Collagen-boosting sheet masks, known for their jelly-like texture.
Sungboon Editor
Deep Collagen Overnight Mask $19
$16
(16% off)
AMAZON
Vogue's beauty commerce writer Conçetta Ciarlo uses Sungboon Editor's Deep Collagen Overnight mask.
Vogue's senior beauty commerce writer Kiana Murden uses Biodance's Bio-collagen Real Deep mask.
Biodance
Bio-Collagen Real Deep Mask
$62
AMAZON
Prime Day Korean Eye Cream Deals
Smartly priced and packed with efficacious ingredients, Korean eye creams deliver visible results without compromising comfort. Whether powered by retinol or antioxidant-rich botanicals, each formula firms and smooths the delicate eye area—while calming agents like centella asiatica and panthenol help prevent irritation. Sulwhasoo's fan-favorite offering feels especially indulgent, combining ginseng actives and vitamin C to visibly soften fine lines, while brightening. Skin1004 and Axis-Y offer more anti-aging options, relying on vegan collagen and plant-based retinol alternatives. Meanwhile, Belif's eye cream leans into hydration, bolstered by peptides and squalane for a plumping, cushiony finish.
Prime Day Korean Moisturizer Deals
'Korean moisturizers are so innovative and thoughtful,' Michelle Park, MD, a board-certified dermatologist based in New York City, previously told Vogue, noting their use of natural, holistic ingredients to enhance skin benefits while addressing a range of concerns. 'Additionally, I think the texture of Korean moisturizers stands out—they're lightweight and non-greasy, yet incredibly effective at hydrating the skin.' For those drawn to barely-there formulas, Beauty of Joseon and IsNtree both offer cult-favorite gel creams that deliver lasting moisture without the weight. Meanwhile, Illiyoon and Purito offer creamier textured formulas rich in calming ingredients like ceramides and oat extract to soothe irritated skin.
Prime Day Korean Sunscreen Deals
Of all the Korean skin-care exports to make waves in the U.S., its range of SPFs might be the most beloved. Korean sunscreens consistently stand out for their advanced formulations: they're often lighter, more refined in texture, and simply more pleasant to wear than many Western counterparts. What really sets them apart, though, is their comprehensive UVA protection—thanks to cutting-edge filters not yet approved for use in the U.S., but widely embraced abroad. Scroll to choose from five different K-Beauty sunscreen favorites, with more picks to come.
Round Lab
Birch Juice Moisturizing Sunscreen $28
$22
(21% off)
AMAZON
Vogue's senior beauty commerce writer Kiana Murden uses Round Labs' Birch Juice Moisturizing Sunscreen.
Prime Day Korean Makeup Deals
The best Korean makeup products boast similarly innovative formulas as their skin-care counterparts, acting as complexion multitaskers—often with imaginative packaging that adds points for function and whimsy. 'In Korea, it's a given that makeup needs to make your skin look amazing,' expert and former Allure editor-in-chief Michelle Lee previously told Vogue. 'Makeup products tend to be quite affordable and have skin-care benefits too,' Lee adds. Among some of the products the Seoul cool girls are using? Tone-adjusting complexion sticks, glitter eyeliner, tinted lip oils, and mascaras that stand up to even the most stubborn of lashes.
Prime Day Korean Hair Care Deals
Much like its approach to skincare, Korean hair care is rooted in a philosophy of prevention, nourishment, and layering lightweight yet potent formulas. The emphasis isn't just on styling but on truly restoring scalp and strand health with ingredients often found in skincare—think collagen, ceramides, and botanical oils. Treatments are designed to be sensorial and effective without feeling heavy or overly perfumed. Case in point: Elizavecca's CER-100 Collagen Coating Hair Protein Treatment aimed at repairing and hydrating damaged strands. For those looking to lock in shine, Mise En Scene's serum delivers a glossy finish without a trace of greasiness. Speaking of hair health, it all starts with the scalp. Dr. Groot's Scalp Revitalizing bundle targets hair loss with biotin and prebiotics, while Celladix offers a hydrating roll-on serum.
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What Factors Influence a Patient's Success on GLP-1s?
What Factors Influence a Patient's Success on GLP-1s?

Medscape

time11 hours ago

  • Medscape

What Factors Influence a Patient's Success on GLP-1s?

Longer treatment duration, not having diabetes, and using semaglutide were among the factors associated with better weight reduction over 12 months among patients taking GLP-1 receptor agonists (RA), a cohort study suggested. 'Treatment responses differ among patients receiving GLP-1 RAs, and the weight fluctuations and associated factors following [their] use have not been adequately characterized,' Linong Ji, MD, of Peking University People's Hospital in Beijing, China, told Medscape Medical News . The findings, published online in Diabetes, Obesity and Metabolism , 'may provide novel insights into weight fluctuations after GLP-1 RA treatment in a real-world setting,' he said, potentially advancing the development of individualized strategies for patients. 'Corroborates Other Studies' Researchers conducted a real-world, single-center, retrospective study of 679 patients with overweight or obesity who initiated GLP-1 RA treatment between November 2022 and October 2024. At baseline, participants had a mean age of 37 years, and 31% were men. The mean BMI was 33.4, and 21% were diagnosed with diabetes. The GLP-1 RAs used in the study included semaglutide (Ozempic), liraglutide (Victoza), lixisenatide (Lyxumia), beinaglutide (Yishengtai), exenatide (Bydureon), dulaglutide (Trulicity), and PEG-loxenatide (Fulaimei). All were available for participants with both type 2 diabetes (T2D) and overweight/obesity. For participants with overweight/obesity but without T2D, only Ozempic or Victoza were routinely prescribed, with off-label documentation and informed consent. Weight measurements were collected during in-person clinic visits, and weight fluctuation curves were stratified into three phenotypes — Successful Weight Reduction, Remaining Stable, and Weight Regain. Subsequently, the association between potential influencing factors and weight fluctuations was estimated by univariate and multivariate logistic regression. Subgroup analyses were performed in participants with obesity, prediabetes, and in those using liraglutide or semaglutide. Researchers found significant differences in the duration of GLP-1 RA treatment across groups at the 3-, 6-, and 12-month follow-ups. The Successful Weight Reduction group had a significantly longer duration of GLP-1 RA treatment than the Remaining Stable group and a longer duration at both the 6- and 12-month follow-ups than the Weight Regain group. Diabetes status also showed group differences. At both the 3- and 6-month follow-ups, the proportion of patients with T2D in the Successful Weight Reduction group was lower than in the Remaining Stable group. Types of GLP-1 RAs varied between groups, and at the 3- and 6-month follow-ups, the Successful Weight Reduction group was more likely to have initiated treatment with semaglutide than the Remaining Stable group. Patients with a longer duration of GLP-1 RA treatment (odds ratio [OR], 1.014) and higher Homeostasis Model Assessment of Beta-Cell Function levels (OR, 4.912) were more likely to achieve successful weight reduction at the 12-month follow-up. Nondiabetic status (OR, 2.176) and using semaglutide (OR, 2.138) were associated with successful weight reduction at the 6-month follow-up. In addition, a higher percentage of body fat in both men (OR, 3.990) and women (OR, 2.266) was associated with successful weight reduction. The weight regain group had a higher baseline estimated glomerular filtration rate than the Successful Weight Reduction group and the Remaining Stable group at 3-month follow-up, especially among participants with prediabetes. Ji said this finding surprised him. Patients with obesity often exhibit a state of renal hyperfiltration, characterized by elevated renal plasma flow and glomerular filtration rate, which can be reversed by weight reduction. The finding suggests that patients with renal hyperfiltration might be less likely to experience durable weight reduction, Ji said. 'However, few studies have revealed similar observations. Therefore, further validations and investigations are still needed for this finding.' Furthermore, the team found a positive nonlinear association of serum creatinine with successful weight reduction at 12 months — a finding that will also require additional investigations to examine the mechanism underlying the association. Overall, Ji concluded that while longer duration of GLP-1 RA treatment using semaglutide, nondiabetic status, and higher percentage of body fat might be associated with better weight reduction, 'basal metabolic rate, skeletal muscle mass, muscle mass of the abdomen and limbs, and serum creatinine were nonlinearly associated with the probability of successful weight reduction.' Randy Seeley, MD, Henry King Ransom Endowed Professor of Surgery, Internal Medicine, and Nutritional Sciences at the University of Michigan School of Medicine, Ann Arbor, Michigan, and director of the National Institutes of Health-funded Michigan Nutrition Obesity Research Center, told Medscape Medical News , 'The main results of the study agree with what the field has already seen. Although it is a relatively small study, it corroborates other larger studies,' said Seeley, who was not involved in the study. This work was supported by the Noncommunicable Chronic Diseases-National Science and Technology Major Project. Ji reported receiving fees for lecture presentations and for consulting from AstraZeneca, Merck, Metabasis, MSD, Novartis, Eli Lilly and Company, Roche, Sanofi-Aventis, and Takeda. Seeley reported that his lab has worked with both Novo and Lilly (and others trying to enter the space), and he has also served as a paid consultant for both of those companies (and others trying to enter the space).

46 Beauty Products You'll Forever Be Glad You Purchased
46 Beauty Products You'll Forever Be Glad You Purchased

Buzz Feed

time11 hours ago

  • Buzz Feed

46 Beauty Products You'll Forever Be Glad You Purchased

Anua heartleaf pore-clearing cleansing oil to dissolve makeup residue, blackheads, and excess sebum *without* clogging pores or over-drying skin. Reviewers say that they could actually see the oils and gunk leaving their face — kinda gross, very satisfying, and a major slay. A viral deep collagen overnight mask — if you've been looking for the ultimate glass skin hack, this is it. The mask goes on white, and once your face has absorbed all the collagen, it turns transparent. Leave it on while you relax for a few hours or even overnight as you sleep, and your face will be super hydrated, firm, and glowy afterward. A painless, mint-flavored teeth-whitening pen to help remove years of staining, and it takes only 30 seconds to apply! Plus, they won't cause sensitivity like other options (*cough* Crest Whitestrips) can. Your teeth will become so white, you'll never want to stop smiling — c'mon, show off those all-natural veneers. L'Oreal's Lumi Glotion — this illuminating moisturizer enhances your skin's natural glow with its shimmering color tint so you can achieve that ~sun-kissed~ look without having to roast in the heat for hours. Reviewers say it's just like the Drunk Elephant bronzing drops — and maybe even better! A pack of 40 acne patches so you can tackle that pesky pimple head-on. These discreet patches help conceal pimples and prevent you from picking at them while the hydrocolloid absorbs the gunk inside — so they can actually heal faster! They're great for daytime or overnight use. Or LivaClean Superstar pimple patches that are so cute, you might not even be that mad at the next pimple you get since you'll have an excuse to put one of these bad boys on. They look just like Starface patches, but for a fraction of the price — and reviewers say these work way better for shrinking blemishes and helping them heal! Plus, nose pore patches to remove the grime and excess oil in your nose that are begging to be released. Just leave it on overnight and take it off in the morning to see all the goop and gunk it pulled out, plus your clearer, smaller pores. Kahi Wrinkle Bounce Hydrating Multi-Balm if you crave that "post-shower feeling" and ✨ glow ✨. This K-beauty product deserves a spot in your arsenal ASAP because it combines the power of lip balm, eye cream, primer, and MORE — what?! Its salmon complex and collagen formula helps reduce fine lines and can keep your skin hydrated for 48 hours. OK, fine, I've convinced myself to buy one. Cosrx Snail Mucin 96% Power Repairing Essence, a cult-favorite for good reason: It soothes dehydrated skin and reduces dullness, and it's perfect for ALL skin types, even if you have oily skin! Don't worry, no snails were harmed in its making (so Gary, you're safe). And Cosrx Snail Mucin 92% Moisturizer if you want to look and feel positively radiant. This wonder product locks in moisture to plump, hydrate, and soothe parched skin. A vegan under-eye brightener that helps reduce dark circles and balance bluish tones using hyaluronic acid and shea butter (that'll also nourish and hydrate skin!). Reviewers praise the results at this low price and compare it to *much* pricier brands! So if you've been staying up well past your bedtime for the past week watching your fave TV show (and it shows around your eyes), this miracle cream will come to your rescue. A stainless-steel skin spatula with vibrations that'll scrape all the gunk from your face, bringing out blackheads, dirt, and oils from your pores! For less than $20, think about how much you'll save instead of going for a facial! An eyelash comb to separate your lashes when your mascara clumps up after applying. Just brush this through a few times, and you're good to go! The bestselling, cruelty-free Essence Lash Princess mascara, which enhances your beautiful lashes with its cone-shaped fiber brush, with such dramatic (+ clump-free) results, you won't need extensions or falsies ever again. Reviewers swear it delivers the same (if not better) results as name-brand mascaras for less than $5 — the 250,000+ 5-star ratings don't lie! An easy-to-use collagen-coating hair mask to treat your dry and damaged hair that's been bleached, dyed, or heat-styled one too many times. Just massage it in, let the collagen and ceramide 3 formula work its magic, and rinse after 5–20 minutes to see some luxurious locks. A bottle of nail and cuticle care oil that can help renew your fingernails after years of nail biting or peeling off acrylics. If your nails are prone to cracking or peeling, the vitamin E and jojoba oil formula will help keep them hydrated and strong! A lil' polar bear hydrating eye stick formulated with Icelandic glacial water, moss and seaweed extracts, and niacinamide to address dark circles, lines, and puffiness — all without oils. If you feel like *nothing* gets rid of those all-nighter eye bags, this might just be your savior. For a top-notch experience, use after refrigeration to help better reduce puffiness! A travel-friendly dry shampoo powder to mattify your roots and hair so no one will know that you haven't washed your mane in a week 😉. Tap the powder into your roots and gently rub it in, and it'll soak up excess oil, leaving your strands feeling as fresh and full as ever! Nyx Brow Glue so you can sculpt your arches to craft your desired shape, volume, and texture. From natural to feathered brows, you can achieve anything with this baby. It doesn't get tacky or flaky like other glues *and* holds up well against sweat! A moisturizing TirTir milk toner if your skin needs a little hydration boost before moisturizing or putting on makeup. It's formulated with chamomile, which reduces redness and irritation, and rice bran extracts to help even skin tone and enhance brightness. A trio of hydrating lip sleeping masks, notably very similar to the Laneige ones (but much more budget-friendly). Each mask nourishes, hydrates, and smooths out your lips overnight, thanks to the berry extract and vitamin C formula — and you get three flavors to try in one set! Your pout will look so supple, it'll leave even Angelina Jolie jealous. Or a soothing (and also Laneige-similar) Jelly Lip Melt that looks like those delicious Jell-O cups we had as kids — ah, the nostalgia. It'll add some gloss to your lips and leave 'em feeling hydrated and plump all day long. A shampoo bar with strengthening rice water protein that'll not only leave you with clean, luscious locks but also encourage hair growth! Reviewers with thin and fine hair love this bar because they say it makes their hair feel fuller, and it can also help with dryness and brittleness. Plus, if you're in your "save the environment" era, it's vegan, zero waste, and 100% compostable. A spray bottle of quick-dry hair and body glitter capable of turning you into a fairy princess because you'll be ✨ shimmering ✨ from head to toe. Reviewers also love that it washes off easily — which, for glitter, is basically unheard of. Glow Recipe's Watermelon Glow, aka a godsend for your pores. Formulated with hyaluronic acid, watermelon extract, and cactus water, this toner not only locks in moisture and helps minimize the appearance of pores and wrinkles but also exfoliates and decongests your skin with PHA and BHAs! True to its name, it'll also leave you with a gorgeous dewy glow. ✨ Juno & Co.'s Clean 10 Cleansing Balm if your face always feels icky even after you've cleansed and removed makeup. Not only will this magical balm (formulated with pearl barley and vitamin E) remove a full face of makeup, but it's also designed to leave ZERO residue or oiliness. On top of that (as if things couldn't get any better), it helps brighten skin and reduce hyperpigmentation. Etude House's Soonjung 2x Barrier Intense Cream, because K-beauty for the win, duh, and with good reason! If you're a victim of dry skin, suffer no longer because this TikTok-fave magical cream will strengthen your skin's barrier to better retain moisture! Wave goodbye to your dry, irritated skin and hello to your smooth, hydrated face. Briogeo leave-in conditioning spray if frizzy hair is the bane of your morning routine. Just spritz it into your damp locks and your dry strands will be revived, leaving you with a shiny, smooth mane. A mini macaron gel manicure kit for when you glance at your nails and think, "Yeeesh," but you're traveling or simply don't have the time to go to the salon. With this cute and convenient kit, you can give yourself a mani from the comfort of your own home or hotel! A bottle of thermal color-changing nail polish because sticking to one color of polish is so blah. Your nails will magically change colors depending on the temp! Or holographic nail polish that'll make your nails shine almost as bright as you. It may not be gel polish, but reviewers swear it lasts a reaaally long time and say it's even better than OPI and Essie! A spray bottle of Verb Ghost Oil designed to tame frizz and flyaways, especially for those who have coarse, thick locks. Next time someone asks how you got your hair like that, just give them a lil' flip and say, "Oh, it was the ghost." An exfoliating mitt that buffs away all those dead, dry skin cells with its viscose fiber material, leaving you smooth as butter. This bb has the gripping power that loofahs and chemical exfoliants don't have, so it does a way better job of removing all the dead flakes. And afterward, your bod will absorb all your moisturizers and lotions even better! Budget-friendly E.l.f. Poreless Putty Primer, which glides effortlessly onto your skin and blurs your pores, creating the perfect base layer for your makeup to grip onto. Its squalane formula keeps your skin hydrated while looking matte, and reviewers find it *quite* similar to Tatcha's Silk Canvas primer and other big-name brands — without the $$$. A velvety lip tint that'll give you the soft matte look you so desire (without feeling heavy or drying out your lips). Its precision applicator makes it super easy to layer on; plus, it lasts ALL day, so you won't waste any time having to retouch! The Flick Stick, a waterproof eyeliner stamp that creates a perfect wing every time! If you're like me and always have to redo it a bajillion times, this is SO worth it. No more wasting eyeliner and running late to plans; all it takes is one stamp on each side and you're DONE! First Aid Beauty's KP body scrub to gently exfoliate dry and rough bumps, especially those caused by keratosis pilaris (aka "strawberry" or "chicken" skin). This scrub can also help decongest pores and remove dead flakes. It's vegan, cruelty-free, and safe for all types of skin! A plant-powered vitamin C serum that helps to even your skin tone and reduce the appearance of dark spots, fine lines, and wrinkles. Over 94,000 (!!) reviewers have given it 5 stars for its truly magical results, and many love it as a budget-friendly alternative to pricey faves like SkinCeuticals. A bottle of silicone-free L'Oréal Eight Second Wonder Water to magically transform dry, frizzy hair, leaving it soft and silky in just — yup, you guessed it — eight seconds! Apply it in the shower after you shampoo, massage it in to let the lamellar formula work its magic, then rinse it out! A miraculous dark circles concealer that provides medium coverage and lasts for up to 12 hours without feeling heavy or looking cakey — score! It's perfect for when you "accidentally" stayed up until 6 a.m. watching Succession, but you can't have your boss knowing, because your tired under-eyes will instead look bright and rested. An adorable TonyMoly exfoliating stick for removing whiteheads, blackheads, and excess sebum. You can just rinse it off with warm water when you're done, so no need to buy those costly one-time-use pore strips! Maple Holistics biotin shampoo that nourishes your scalp so your locks can grow in thicker than ever with its keratin, rosemary oil, tea tree oil, and — of course — biotin formula. If your hair is thinning, this stuff can be transformative over time. O'Keeffe's hand cream, a tried-and-true savior for extremely dry, cracked hands. It's a concentrated moisturizer (unscented and non-greasy!) that'll actually keep 'em hydrated instead of wearing off after an hour. A skin solution that can be used anywhere you routinely remove hair, whether that be your 'pits or down there. 🤫 Use it right after shaving or waxing to get rid of bumps, ingrown hairs, and rashes. Cruelty-free Thank Me Later eyeshadow primer to make your eyeshadow *pop* and enhance the color. It also combats oil and prevents creasing, and reviewers say their eye makeup lasts all day thanks to it! It's comparable to MAC Paint Pot, but your bank account will ~thank me later~ if you get this one. A powerful 2% BHA salicylic acid exfoliant that helps remove dead skin, shrink and unclog pores, and smooth wrinkles. Soooo many reviewers rave about it clearing their acne and reducing breakouts, too. Talk about benefits on top of benefits!

DLBCL: FDA Rejects BLA for Second-Line Glofitamab Combo
DLBCL: FDA Rejects BLA for Second-Line Glofitamab Combo

Medscape

time12 hours ago

  • Medscape

DLBCL: FDA Rejects BLA for Second-Line Glofitamab Combo

The FDA rejected a supplemental Biologics License Application (sBLA) for glofitamab-gxbm (Columvi, Genentech) in combination with gemcitabine and oxaliplatin for the second-line treatment of relapsed or refractory diffuse large B-cell lymphoma (DLBCL) in patients who are not candidates for autologous stem cell transplant. A complete response letter from the FDA stated that Genentech's phase 3 STARGLO trial did not provide sufficient evidence to support the proposed second-line DLBCL indication for the T cell engaging bispecific antibody in the US, according to a Genentech statement. However, a conditional FDA approval in the third-line or greater setting remains in place. FDA's decision regarding second-line glofitamab aligns with an advisory committee vote in May, which cited a lack of US patient representation in the trial. The Oncologic Drugs Advisory Committee (ODAC) voted 8-1 against recommending approval, as reported by Medscape Medical News . The FDA asked for ODAC review over concerns that nearly half of the STARGLO participants were from Korea, Taiwan, and China, with most of the remaining participants coming from Europe and Australia. Only 25 US patients were included. Outcomes among Asian vs non-Asian patients differed, with a strong trend toward worse overall survival (OS), rates in White patients and patients from Europe and the US, despite a strong overall 0.59 hazard ratio for OS. Similar trends were observed for progression-free survival and complete response rates. At the time, the FDA said the low US enrollment 'limits the agency's ability to assess the applicability of the study results to a US patient population,' and cited additional concerns regarding comparator drugs used in the trial, according to meeting documents. 'While we are disappointed with this outcome, we remain confident in the data supporting the value of Columvi for US patients who have relapsed following initial treatment, and its key role as monotherapy in the third-line setting,' Genentech's Chief Medical Officer and head of Global Product Developments, Levi Garraway, MD, PhD, said in the company statement regarding the sBLA rejection. 'We are committed to bringing Columvi to more people living with lymphoma and are actively exploring its potential in additional treatment settings, including as frontline therapy.' 'For patients with this aggressive form of lymphoma, effective treatment after relapse is paramount,' added Jeremy Abramson, MD, the principle STARGLO investigator and director of the Jon and Jo Ann Hagler Center for Lymphoma at the Massachusetts General Hospital Cancer Center, Boston. Abramson stressed that in the STARGLO trial, the glofitamab combination therapy improved OS, which 'could have a positive impact for patients earlier in their treatment journey.' The regimen is currently approved for this indication in more than 35 countries. It is approved in more than 60 countries for third-line or greater treatment of DLBCL, including in the US where the FDA granted accelerated approval in 2023. STARGLO was also intended as a post-marketing confirmatory study to support conversion of the accelerated approval to full approval, Genentech noted. Results were published in 2024 in The Lancet, and 2-year follow-up data showing sustained overall improvements in the primary and secondary endpoints were presented at 2025 American Society of Clinical Oncology Meeting. Genentech said the regimen is currently being investigated in combination with other agents as a first-line treatment for DLBCL in the phase 3 SKYGLO study.

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