
AGC Biologics Expands Cell Therapy Development Operations to Asia to Serve Growing Market Need
This new site precedes the opening of a new AGC Biologics Yokohama manufacturing facility on schedule to be operational in 2027 with pre-clinical through commercial services for mammalian-based protein biologics, cell therapies, and messenger RNA.
The Yokohama location will provide process transfer and manufacturing services for pre-clinical and clinical trials to serve an expanding global cell therapy market. Its core technologies include induced pluripotent stem cells, mesenchymal stem cells, hematopoietic stem cells, and CAR-T cell therapies. AGC Biologics Cell and Gene Technology Center of Excellence in Milan, with its nine product approvals by the EMA and FDA, hundreds of batches manufactured, and 30-year track record, will support and enable the successful ramp up of operation in the new Yokohama site.
'In a cell and gene therapy market of high volatility and witnessing consolidation of CDMOs, AGC Biologics is among the few experiencing significant growth and success. We are now building on this success to complete the vision of having a truly global offering,' said Luca Alberici, Executive Vice President of Global Cell and Gene Technologies at AGC Biologics. 'Now Asian developers can benefit from having a local supply within one of the best global infrastructures on the market for cell therapy. Moreover, customers can continue to leverage the offering of viral vector central supply in our Milan facility, which supplies around a third of the ex vivo gene therapy product approved for commercialization. AGC Biologics, through its proprietary ProntoLVV and BravoAAV platforms, aims to offer viral vectors at a sustainable cost for its clients targeting less than 1,000€ per CAR-T patient.'
'Our team of friendly experts in Milan have a strong reputation for collaboration and working side-by-side with customers to achieve clinical, late-phase, and commercial successes,' said Jun Takami, Senior Vice President and General Manager, Japan Region and Yokohama Facility. 'As part of this next major phase for cell therapy in the region, our Yokohama team is ready to support partners in accelerating drug development timelines while maintaining the highest quality standards in the industry."
AGC Biologics is a part of AGC Inc.'s Life Science Company. The Life Science company operates over 10 facilities worldwide focused on biopharmaceuticals, advanced therapies, small molecule active pharmaceutical ingredients, and agrochemicals. The AGC Inc. Yokohama Technical Center, built in 2020, is dedicated to advancing AGC Inc.'s research and development capabilities in materials science, chemical processes, and biotechnology.
Please visit www.agcbio.com to learn more about AGC Biologics' global network of services for protein biologics and cell and gene therapies.
About AGC Biologics
AGC Biologics is a leading global biopharmaceutical Contract Development and Manufacturing Organization (CDMO) with a strong commitment to delivering the highest standard of service as we work side-by-side with our clients and partners, to provide friendly and expert services. We provide world-class development and manufacturing of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), messenger RNA (mRNA), viral vectors, and genetically engineered cells. Our global network spans the U.S., Europe, and Asia, with locations in Seattle, Washington; Boulder and Longmont, Colorado; Copenhagen, Denmark; Heidelberg, Germany; Milan, Italy; and Chiba and Yokohama, Japan. We currently employ more than 2,600 Team Members worldwide.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Business Wire
6 hours ago
- Business Wire
Terra Firma Energy Welcome UK Government Consultation on Hydrogen Blending into Great Britains Gas Transmission Network
LONDON--(BUSINESS WIRE)--At Terra Firma Energy, we welcome the UK Government's consultation into the blending of Hydrogen into Britain's Gas Transmission Network as a timely and positive step forward for both the UK's decarbonisation goals and the future of flexible power generation. All our projects are engineered to be hydrogen-ready from the outset, ensuring long-term operational flexibility and resilience in a rapidly evolving energy landscape. By anticipating changes in fuel supply and regulatory frameworks, we have future-proofed our generation assets to adapt quickly to low-carbon solutions like hydrogen blending. The ability to support hydrogen integration, even at early-stage blend levels, reinforces our commitment to sustainable innovation and positions our portfolio to contribute meaningfully to a net zero grid. Terra Firma Energy welcome UK Government Consultation on Hydrogen Blending into Great Britains Gas Transmission Network. Share The Department for Energy Security and Net Zero (DESNZ) has launched a new consultation exploring the potential for blending low-carbon hydrogen into Great Britain's gas transmission network. Following previous consultations on hydrogen blending into local distribution networks, the government is now seeking views on whether introducing hydrogen at the transmission level - the high-pressure National Transmission System (NTS) - could offer strategic and economic value. A Step Toward Net Zero Hydrogen is seen as a key player in the UK's push to reach net zero emissions by 2050. Blending low-carbon hydrogen with natural gas could offer a transitional path, supporting early-stage hydrogen production while reducing the carbon intensity of the existing gas network. DESNZ is currently evaluating whether to enable blending of up to 2% hydrogen by volume into the NTS. This small percentage could act as an 'off-taker of last resort' for hydrogen producers, providing a backup market when dedicated customers are not available. Balancing Innovation with Risk The consultation outlines both the potential benefits and challenges. While hydrogen blending could support the growth of the hydrogen economy and help manage electricity system constraints, it also raises concerns for industrial users connected to the transmission system. Many of these users rely on stable, high-quality gas supplies, and even a 2% hydrogen blend could affect equipment performance, increase costs, or require infrastructure upgrades. Terra Firma Energy have been proactive in ensuring all our projects have been built utilising hydrogen ready generation sets that can accommodate a 20% blend of hydrogen into the network. Studies cited in the consultation show that most transmission-connected users could technically handle a 2% blend with minimal changes, though feasibility studies and equipment modifications may still be necessary. At higher blends (5% or 20%), the risks and costs escalate significantly. Cross-Border Considerations The UK's ability to blend hydrogen is also influenced by developments in the EU. Under the EU Hydrogen and Decarbonised Gas Market Package, Member States can blend up to 2% hydrogen by volume, but are not required to do so. This creates potential interoperability issues with the UK's gas inter-connectors to Ireland, Belgium, and the Netherlands - especially if hydrogen blends exceed that threshold.


Business Upturn
13 hours ago
- Business Upturn
Why China is pursuing Taiwan: Geopolitical objectives, potential outcomes, and public theories explained
Over the past decade, China's rhetoric, military build-up, diplomatic pressure, and policy strategy surrounding Taiwan have intensified—leading many to question whether a full-scale capture of Taiwan is inevitable. This analysis explores China's motivations, what would change if control is established, and the dominant geopolitical narratives discussing this issue. 1. Historical and ideological roots Civil War legacy: Taiwan is governed by the Republic of China (ROC), which emerged victorious in a 1912–1949 civil war. China's Communist Party established the People's Republic of China (PRC) in 1949 and has never renounced the use of force to bring Taiwan under Beijing's jurisdiction. Article 8 of China's 2005 Anti‑Secession Law formalizes this. National reunification principle: The PRC's official policy—'one China' and Xi Jinping's 'peaceful reunification' under the 'one country, two systems' framework—frames Taiwan as a breakaway province rather than a separate international entity. Political legitimacy: Taiwanese unification is a powerful domestic symbol for the CCP, often used in propagating nationalism and consolidating Xi's political mandate internal to China. 2. Strategic and economic incentives a. Strategic position and power projection Military anchoring in the First Island Chain: Taiwan sits on the so-called 'first island chain,' providing strategic depth in the Western Pacific. Controlling it would significantly extend China's naval and air capabilities, reducing US forward-operating access. Maritime chokepoint control: The Taiwanese straits are adjacent to vital shipping lanes—roughly 60 per cent of Asian maritime trade flows through nearby corridors. Chinese dominance over Taiwan would strengthen its hold over the South China Sea's commercial arteries. b. Technological and economic gain Semiconductor supremacy: Taiwan is home to TSMC, the world's largest semiconductor foundry, responsible for over 50 per cent of global chip fabrication. Full integration could accelerate China's ambitions in semiconductor independence and technological parity. Supply chain control: Taiwan plays a central role in global supply chains—particularly in electronics and green technology manufacturing. Its absorption would give China a critical advantage in these sectors. 3. What would change if China controls Taiwan? a. Shifts in global security and balances of power Decline of US strategic influence in Asia: Losing Taiwan would seriously weaken Washington's ability to project force in the Western Pacific and could unravel alliances with Japan, Korea, and Australia. Expansion of China's 'kill‑chain' reach: Models show that with Taiwan under PRC control, air-and-missile denial coverage expands, forcing US bases like Guam or the Philippines to operate at reduced effectiveness. b. Global economic fallout Unprecedented disruption: Even a brief conflict or aggressive blockade over Taiwan could cost the world economy over $10 trillion—short-term shocks similar to, or bigger than, the Ukraine war or 2008 financial crisis. Impact on capital and technology: Taiwan is a key conduit for foreign-invested capital and advanced microelectronics. Its loss could throttle foreign inflows, affecting Beijing's broader innovation-driven growth strategy. c. Political and cultural consequences Erosion of democratic autonomy: Taiwan's integration would mean dissolving its democratic institutions, curtailing civil liberties, and subsuming it under the PRC's authoritarian model—something sharply resisted by approximately 90 per cent of Taiwanese people. Continued 'political warfare': China would likely escalate its cognitive warfare campaigns—disinformation, political infiltration, propaganda—aimed at conditioning Taiwanese public opinion to accept Beijing's supremacy. 4. Public and strategic theories on Beijing's motivations Theory / Framework Key Idea Source Great Power Assertion Annexing Taiwan reinforces China's self-declared status as a leading global power, challenging the U.S.-led world order. Reddit , Wikipedia , Barron's 'Cognitive Warfare' Mastery Over time, China could annex Taiwan without force by eroding public will through propaganda and election manipulation. TIME , Wikipedia 'Anaconda Strategy' Beijing applies gradual diplomatic, economic, and military pressure to strangle Taipei's autonomy before physically seizing control. Council on Foreign Relations , Small Wars Journal Premptive Window Strategy Some Western analysts argue China might strike before U.S. internal political changes reduce deterrence or alliances weaken. Reddit , , Domestic Consolidation Taiwan serves as a rallying symbol at home, diverting attention from domestic issues and strengthening leadership legitimacy. Reddit , Small Wars Journal 5. Challenges and limits to a Taiwan takeover Massive military cost and human toll: Models show an amphibious invasion would be extraordinarily difficult—due to Taiwan's terrain, US and allied intervention, and Taiwan's own reserve mobilization plan. Economic blowback: China would face isolation from global markets, capital outflows, and loss of critical technology access—particularly in high-end semiconductors and foreign investment. Domestic risk amid PLA reforms: Xi's ongoing military leadership reshuffle raises questions about the People's Liberation Army's readiness for such a complex operation. 6. What the international community is doing US deterrence doctrine: US policymakers advocate a 'reassure and deter' framework—maintaining ambiguous support for Taiwan's defense while discouraging aggressive PRC action. Allied formation in the Indo-Pacific: Countries like Australia and Japan have pledged closer defense cooperation. A US congressional delegation is visiting Taiwan to reaffirm support. Taiwan civilian readiness: Under the 'Territorial Defense Force' model, Taiwan is enhancing its reserve system and investing in low-cost mobile defense weapons to make occupation prohibitively costly. Conclusion China views Taiwan as integral to its national identity and global power projection plan, but control requires overcoming immense global and domestic resistance. Economic gain and strategic depth are key motivators, yet the full takeover presents massive economic and geopolitical costs, including undermining Beijing's longer-term modernization strategy. Multiple scholarly frameworks—from great power theory to cognitive and political warfare—explain why China may pursue Taiwan even short of war. International deterrents and Taiwan's own resilience planning are central to preventing conflict, although no one can accurately predict Beijing's next move. Ahmedabad Plane Crash Vipul Sipani is a qualified IT professional with over eight years of active working experience. He is a trained web technologist and a certified Ethical Hacker v8 security analyst. Vipul has also been a consultant with the detection and prevention of cyber crimes, with the Cyber Crime Investigation Cell (CCIC) of Rajasthan State Police. Vipul is currently working as editor-in-chief at and he is reachable on [email protected]
Yahoo
a day ago
- Yahoo
UnitedHealth Group Announces Changes to Leadership Team
July 31, 2025--(BUSINESS WIRE)--UnitedHealth Group (NYSE: UNH) today announced Wayne S. DeVeydt has been appointed its chief financial officer, effective September 2, 2025. John F. Rex, who joined the company in 2012 and has been CFO since 2016, will become strategic advisor to the CEO on the same date. "Wayne DeVeydt combines deep financial acumen and operating experience with the mission-oriented and compassionate approach to health care that is a perfect fit for UnitedHealth Group," said Stephen J. Hemsley, company chairman and chief executive officer. "John Rex has been an exceptional leader, having helped guide our company through substantial change with both strategic vision and strong commitment to our mission," said Hemsley. "I look forward to his continued insights as UnitedHealth Group moves forward." DeVeydt, 55, most recently has been a managing director and operating partner at Bain Capital, working with client leaders on operational improvement and growth acceleration. From 2018-2020, he was chairman and CEO of Surgery Partners, Inc. in Nashville, expanding the operational scale and financial performance of the surgical services firm. He joined Anthem, Inc. (now Elevance) in 2005 and served as its chief financial officer from 2007 to 2016. Prior to joining Anthem, DeVeydt served as a partner with PricewaterhouseCoopers LLP, with a focus on the health care sector. "There is no organization besides UnitedHealth Group that presents the kinds of opportunities to make a difference in health care, from individual patient care to broad system efficiency, so I am eagerly looking forward to joining the team," said DeVeydt. "I've been fortunate to know John Rex for over two decades and am honored to follow a leader of his caliber." Rex, 63, joined UnitedHealth Group as chief financial officer of the company's then newly established Optum business and previously had spent his career focused in health care across multiple roles and sectors. "This pivotal moment for UnitedHealth Group is the right time for a new yet greatly experienced executive like Wayne DeVeydt, and I look forward to supporting him and the entire leadership team while continuing to advise on a range of matters," said Rex. About UnitedHealth Group UnitedHealth Group is a health care and well-being company with a mission to help people live healthier lives and help make the health system work better for everyone through two distinct and complementary businesses. Optum delivers care aided by technology and data, empowering people, partners and providers with the guidance and tools they need to achieve better health. UnitedHealthcare offers a full range of health benefits, enabling affordable coverage, simplifying the health care experience and delivering access to high-quality care. Visit UnitedHealth Group at and follow UnitedHealth Group on LinkedIn. View source version on Contacts Media: uhgmedia@ UnitedHealth Group Media Sign in to access your portfolio