
Bug, MD: Meet the surgeons and doctors of the wild
They self-medicate, and they do it better than us.
Bears, for instance, eat willow bark after their long winter snooze. Rich in salicin, the bark helps cleanse the bear's system and ease the stiffness and aches that may have set in, during the still winter months.
Incidentally, salicylic acid drawn from salicin is used in our painkillers too; it's helped us make aspirin since 1899.
Now to more dramatic examples. Florida carpenter ants perform surgery on each other, to increase an injured buddy's chances of survival. A study published in the journal Current Biology last year detailed how an ant will bite off an injured colleague's infected upper leg to save its life, with a success rate of 90% for such amputations, against a survival rate of about 40% in cases where such an injury is left untreated.
Meanwhile, earlier this year, a study published in the journal Science reported that mice sometimes perform a kind of CPR on each other. In their experiment, researchers drugged a mouse and waited for it to fall unconscious. When it did, a fellow mouse aggressively opened its mouth and pulled out its tongue, helping open its airways quite effectively.
Such actions are not deliberate, in the way that we define deliberate, but they're not pure instinct either, says Jaap de Roode, a professor of biology at Atlanta's Emory University and author of the new book Doctors by Nature: How Ants, Apes, and other Animals Heal Themselves (Princeton University Press; March 2025).
The book compiles findings from scientists around the world, and details observational studies and experiments on this intriguing subject.
In modern science, the field is referred to as zoopharmacognosy (the study of animal self-medication). It is generally dated to the 1980s, when primatologist Michael Huffman and traditional healer Mohamedi Seifu Kalunde observed a mother chimpanzee in Tanzania ease a gut infection by swallowing the bitter leaves of the mjonso shrub, and then teach her infant to do the same.
'Back then, many Western scientists wouldn't believe it. They said there was no way animals could have the mental capacity to self-medicate, because they didn't have the intellect of humans,' de Roode says. 'With mounting scientific evidence, they started accepting it, but only because the chimpanzees are our distant cousins and have large brains.'
Over time, of course, humans learnt (and grew to accept) that several species have tools, cultures and customs. They may not evolve, as our cultures do. But they are passed down: the paths to healing, the use of basic tools, the best ways to raise young.
Winging it
The point of his book, de Roode says, is to shatter our human-centric perspective.
It drives much of what the 47-year-old does. His area of focus as a researcher, for instance, is the monarch butterfly. So, every year, at the St Marks Monarch Butterfly Festival in Florida, he holds specialised tours to explain why these orange-winged, polka-dotted creatures are 'expert doctors'.
'Insects are the most diverse group of animals on earth and they've been around for much longer — some 479 million years, against less than 200 million for mammals,' he tells them. Behind that ability to survive is a degree of adaptability to hurt — and a body of 'knowledge' about how to stay healthy.
Both wood ants and honeybees, for instance, collect and apply resins to their nests and hives to keep bacteria and fungi away and protect the health of the colony.
Woolly bear caterpillars eat as many as five plant species a day, to stock up on vital alkaloids. These nitrogen compounds are their primary line of defence when a tachinid fly lays eggs on them. As the larvae hatch, they chew on the little woolly bug. The alkaloids are toxic to the larvae, and this helps raise the caterpillar's odds of surviving (from 40% to 60%).
The really interesting bit: the alkaloids can be toxic to the little caterpillar too. It has to 'know' just how much to ingest.
Sage advice
Even plants have 'learnt' how to protect themselves.
Over time, as insects and animals evolved, plants began to encounter new threats, and developed the ability to produce toxins that work to stop these creatures from eating them. 'It is often these very compounds that act as medicines for animals — and for humans,' de Roode says.
Humans also gathered knowledge as they evolved, and passed it down, even though they couldn't explain why certain herbs heal or why others go into a salve. And so it is that we are now discovering antioxidants and anticarcinogens in the things our grandparents told us to eat.
'Many of the scientific discoveries of the last decades are in fact rediscoveries of traditional knowledge,' de Roode writes. There could still be cures in plain sight, he adds.
Researcher Cassandra Quave of Emory University is studying the sweet chestnut tree in her attempts to treat certain skin conditions, based on a tip she received from Italians and the Albanian Arbereshe community.
At the University of Kinshasa in the Congo, Ulrich Maloueki is studying which elements in primate diets contain antimalarial agents, in attempts to develop new drugs for humans.
We once ate food that doubled as medicine too. There are certain cultures (think of south India) that still largely adhere to seasonal eating habits, balance meals depending on time of day and time of year. In such cultures, as in the animal kingdom, food itself becomes the first line of defence against illness.
In a world of rapid extinctions, this is something to think about too.
'It is not just the animals we are losing,' as de Roode puts it. 'With every animal we lose, we lose another medical expert and another opportunity to discover new compounds that we may want to develop as medicines for ourselves.'
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


The Hindu
3 hours ago
- The Hindu
A new BHARAT- establishing baseline health parameters for the Indian population
We don't all age the same way, but we all do age. We intuitively recognise frailty when things start to slow down. Ageing unfolds at different rates, over time, between individuals, within and across populations. Often, it happens in bursts. Ageing is complicated. It is driven by molecular and cellular interactions and is shaped by one's environment, lifestyle, and socioeconomic conditions. This means one's chronological age often doesn't reflect how old one's body really is. Since researchers discovered in 1935 that ageing can be altered, they have been looking for reliable biological clues, called biomarkers, that in isolation or together can indicate how old our bodies are and how they might respond to factors such as diet, exercise, etc. Biomarkers of ageing Last year, the Indian Institute of Science (IISc), Bengaluru, launched a large-scale study called BHARAT, short for 'Biomarkers of Healthy Aging, Resilience, Adversity, and Transitions', as part of its Longevity India Program. The study aims to map the physiological, molecular, and environmental indicators that drive ageing in the Indian population. 'We lack clear information on what features define or influence healthy ageing,' says Deepak Kumar Saini, convener of BHARAT and professor of development biology and genetics at IISc. 'We are building an information portal to understand the rules of healthy ageing in Indians.' Worldwide, life expectancy has risen significantly over the past few decades. In India it climbed 4.1 years to 67.3 in the first two decades of this century. Living longer doesn't mean living healthier, however. Studies have predicted a 168% increase in Parkinson's disease cases in India by 2050 and a 200% rise in dementia across low- and middle-income countries. Yet much of what we know about health and disease risk comes from studies in Western populations, which means the diagnostic tools, biomarkers, and even treatments may not be optimal for people in India or other non-Western countries. Gaps for patients in Global South This limited focus has created a gap between population-based biomarkers and diagnostic cut-offs for people in the Global South. This can lead to misdiagnosis and treatments that don't reflect how diseases progress or respond to therapeutics in different groups. 'Western values for cholesterol, vitamin D, or B12 may label many Indians as deficient. But are these truly abnormal within our context? Our study aims to answer that. We are not only identifying biomarkers for healthy ageing but also building the Bharat Baseline — a reliable reference for what is normal in the Indian population,' Prof. Saini says. Earlier this year, researchers from Sichuan, China, reported in Scientific Reports that certain biomarkers for breast cancer, such as high levels of high-density lipoprotein cholesterol, could signal an elevated risk in European populations but may serve as supportive indicators in Asians. 'We see differences in inflammatory markers. For instance, C-reactive protein (CRP) levels tend to be elevated in Indians even without acute illness. This inflammation often results from early-life infections, environmental toxins, or chronic nutritional and metabolic issues,' Shawn T. Joseph, senior consultant, head and neck surgical oncology, VPS Lakeshore Hospital in Kochi, says. 'Applying Western CRP cut-offs risks missing early warning signs of cardiovascular or metabolic disease in Indian patients,' he adds. An India-specific database BHARAT's goal is to change this. Its database will include genomic biomarkers (like mutations linked to disease susceptibility), proteomic and metabolic indicators (reflecting biological pathways and metabolic health), and environmental and lifestyle factors. Identifying early warning signs of age-related changes can enable better prediction, intervention, and potentially delay the onset of disease. There is a need for proactive markers of health, indicators that can tell when an organ is functioning below its optimal level, even if it is not yet diseased. For instance, your liver age is more than your chronological age. To do that, researchers must sift through large, many-dimensional datasets and plan to take the help of artificial intelligence (AI) models. 'AI and machine learning are essential to integrate and analyse layered data to see the full picture. It can simulate the impact of interventions and augment existing datasets to improve signal detection that may otherwise be missed in high-dimensional, small-sample studies. This will help us choose the most effective interventions before launching costly trials,' says Tavpritesh Sethi, professor of computational biology at the Indraprastha Institute of Information Technology, Delhi, who is also one of the investigators of BHARAT. However, if the AI models' training datasets don't reflect local realities, they risk perpetuating health inequities. India's population is genetically, environmentally, and socioeconomically diverse. Capturing this diversity in a single database is crucial but also logistically complex. Prof Saini anticipates a few challenges, including the difficulty of obtaining samples from healthy adults, securing long-term government and philanthropic funding, and expanding the study to collect samples from across the country. (Rupsy Khurana is science communication and outreach lead at the National Centre for Biological Sciences, Bengaluru.


Indian Express
18 hours ago
- Indian Express
How a CIA operation stopped Pakistanis from getting vaccinated against polio
In the dry, mountainous district of North Waziristan, 19-month-old Ahmad became Pakistan's 14th confirmed polio case of 2025. His diagnosis, reported on July 1 by the National Institute of Health in Islamabad, pushed the year's total in Khyber Pakhtunkhwa province to eight. That figure may seem small, but it's a grim reminder: Pakistan remains one of only two countries in the world where polio is still endemic. Pakistan has fought hard against polio, slashing cases by over 99 per cent, according to Federal Health Minister Syed Mustafa Kamal. Decades of door-to-door vaccination drives, brave health workers, and global support have pushed the virus to the brink of extinction. But the fight isn't just against a disease. It's against poverty, conflict, and a lingering wound inflicted by a CIA operation more than a decade ago. In 2011, a shocking secret came to light: the CIA had used a fake vaccination campaign in Abbottabad, Pakistan, to hunt for Osama bin Laden. It was a move no one saw coming, and its fallout would ripple for years. Reports from The Guardian and The New York Times revealed that the CIA, desperate to confirm if bin Laden was hiding in a local compound, enlisted a Pakistani doctor named Shakil Afridi. His job? Run a pretend hepatitis B vaccination drive for kids in the area. But the needles weren't just for vaccines—they were a cover to collect DNA samples, likely through blood or saliva, from children near the compound. The hope was to match the samples to DNA from bin Laden's sister, who'd died in the US the year before, to prove if her brother—the elusive 'Pacer' the CIA was tracking—was really there. The mission worked; Bin Laden was killed. But America's success came at Pakistan's cost. Once news spread of the fake vaccination campaign, the backlash was swift and far-reaching. Many Pakistanis saw the episode as confirmation of their worst suspicions: that Western aid programs could be Trojan horses for intelligence operations. Public trust in vaccination campaigns, already fragile in parts of the country due to conspiracy theories and religious opposition, was severely damaged. 'Release of this information has had a disastrous effect on worldwide eradication of infectious diseases, especially polio,' The Lancet later reported. Militant groups used the episode to reinforce conspiracy theories that vaccinations were a Western plot. In the years since, polio workers have been targeted by extremists, forced to operate under armed escort. In Balochistan last November, a bomb tore through a police escort for vaccinators, killing nine, including five children. In Khyber Pakhtunkhwa, 20 health workers and guards have been killed in similar attacks. The violence forced groups like the UN to pause vaccination efforts, leaving millions of children unprotected. As the violence increased, so did mistrust. According to Dawn, Pakistan's leading English daily, the numbers from recent immunisation drives are staggering. 'Khyber Pakhtunkhwa reported 19,070 refusals against oral polio vaccine in February,' the paper reported. Additionally, nearly 100,000 children were simply not home when health workers came – possibly because parents intentionally kept them away. A study by researchers Monica Martinez-Bravo and Andreas Stegmann showed how the CIA's ruse gutted vaccination rates. In areas with strong support for extremist groups, vaccinations for polio dropped 28 percent, measles 39 per cent, and other diseases 23 per cent following the revelations. In some Taliban-controlled regions, vaccines were banned outright. The CIA's promise in 2014 to never again use health programs for spying came too late. The damage was done. Vaccination refusal became ideological. This growing mistrust has left the last mile of eradication out of reach. Meanwhile, attacks on health workers have become routine. Fear stalks every door-to-door visit. Paranoia thrives in the absence of trust. And a virus that should have been confined to history now clings to life—in part because public health was once used as a weapon of war.


Time of India
18 hours ago
- Time of India
Make cell and gene therapy more affordable: PSA tells experts
BENGALURU: As innovations in cell and gene therapies have taken root in India, Ajay K Sood, Principal Scientific Advisor, Govt of India, reminded scientists and innovators in Bengaluru, on Thursday, that efforts should be made to make these therapies affordable. The govt is also looking at a national mission that drives this affordability. Talking to experts at the India AMR innovation workshop at CCAMP in Bengaluru, Sood said, "Very often we see cell and gene therapies, which all of you are experts in, and if you look at the cost, that is really something which is not affordable in most countries — even in other developed countries. If you have to really make these therapies accessible, a large effort is needed. Innovations are taking place in isolated pockets, but the effort has to be amplified. " Sood, who also chairs the Prime Minister Science, Technology and Innovation Advisory Council, told TOI: 'Cell and gene therapy was discussed extensively in the recent meeting where we bring out various issues which have to be raised to the level of a mission. You Can Also Check: Bengaluru AQI | Weather in Bengaluru | Bank Holidays in Bengaluru | Public Holidays in Bengaluru We all felt it has to be a multi-ministerial effort, and we will need resources for that — it will be made into a mission — 'a cell and gene therapy mission'. The idea is how do we really make affordable cell and gene therapy products. While research is going on in a few labs and institutes, lots has to be done to take it to the market.' He added, 'First, you need the science and technology to make those molecules. After that, it has to be at scale to bring down the cost. One needs a holistic view that they are not only doing it for the country but for the globe. Both things have to go hand in hand.' 'We have to create a way to make our own chemicals. Unless we make that, we cannot reduce the cost. So that has to be, that is what is being done in this, at least in the IIT Bombay, and we will do in the mission,' he said. He added that therapy like 'ImmunoACT (the CAR-T cell therapy) is heavily supported by govt with initial funding from DBT, ICMR, and DST. How they take it to further reduce the cost is where all the private factors will come in, and they are already coming in.' Quantum Computing in drug discovery Meanwhile, Sood also believed that one can't avoid the use of quantum computing in biological sciences — "Billions of dollars are pouring in on drug discovery using quantum computing. That will be a game changer because all those huge permutation combinations will be so trivially done in quantum computing. This is really the future along with materials discovery and so on.' Antimicrobial resistance Talking about antimicrobial resistance being a prevalent issue, Ekroop Caur, Secretary, IT, BT, ST department, said, "Even though we may not take antibiotics or we may not misuse antibiotics, we are still affected by it — because what happens in the animal world and plant world will have an impact on us. This also calls for very strong pharmaceutical regulations, which is part of Karnataka's AMR action plan formulated in 2024." Taslimarif Saiyed, CEO and Director, CCAMP, pointed out the risk of nearly 10 million people dying annually from AMR — "I don't think one can step back and say we will look at it when it happens. I think collectively all of us are here to say how much I can take down from the 10 million.'