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Trump reiterates frustration over auto trade with Japan

Trump reiterates frustration over auto trade with Japan

NHK6 hours ago
US President Donald Trump has reiterated that he believes Japan isn't doing enough to open its markets to US exports, in particular in the auto industry.
Trump was speaking to reporters at an Air Force base outside Washington on Sunday about tariff negotiations with Japan and other countries and regions.
He said that while the European Union wants to open up its markets, Japan has done so "to a much lesser extent, in terms of opening up their country."
Trump repeated his claim that Japan sells the US "millions and millions" of cars a year and that Japan won't accept US autos or much agricultural products.
He went on to say that Japan and other US trading partners are "all changing their ways very, very rapidly."
The US president offered no details about what he meant by "changing their ways."
Trump announced on July 7 that he will impose a 25 percent tariff on imports from Japan starting on August 1.
Attention is focusing on Japan-US tariff negotiations and whether they can narrow disagreements between the two countries.
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China biotech's stunning advance is changing the world's drug pipeline
China biotech's stunning advance is changing the world's drug pipeline

Japan Times

timean hour ago

  • Japan Times

China biotech's stunning advance is changing the world's drug pipeline

The biotechnology industry is experiencing a tectonic shift, driven by Chinese drugmakers who have come a long way from their copycat days to challenge Western dominance on innovation. The number of novel drugs in China — for cancer, weight-loss and more — entering into development ballooned to over 1,250 last year, far surpassing the European Union and nearly catching up to the U.S.'s count of about 1,440, an exclusive Bloomberg News analysis showed. And the drug candidates from the land once notorious for cheap knock-offs and quality issues are increasingly clearing high bars to win recognition from both drug regulators and Western pharmaceutical giants. The findings, gleaned from an analysis of a database maintained by pharma intelligence solutions provider Norstella, show a fundamental shift in medical innovation's center of gravity. With U.S. President Donald Trump already threatening tariffs on the pharmaceutical sector, China's biotech advances — the scale of which is slowly coming into view — risk becoming another realm of superpower rivalry like artificial intelligence and electric vehicles. "The scale itself is not something we've seen before,' said Helen Chen, managing partner at LEK Consulting in Shanghai, who has advised healthcare companies on their China strategy since 2003. "The products are here, they're attractive and they're fast.' This shift has occurred at an unprecedented pace. When China began to overhaul its drug regulatory system in 2015, the country had just 160 compounds to contribute to the global pipeline of innovative drugs, or less than 6% of the total, behind Japan and the U.K. The reforms helped streamline reviews, enforced data quality standards and improved transparency. The government's "Made in China 2025" plan to elevate manufacturing in 10 priority sectors also helped spur a flurry of investments in biotechnology. Altogether, they unleashed a boom led by foreign-educated and -trained scientists and entrepreneurs. "Not only is it now almost at parity with the U.S. but it has that growth trajectory,' said Daniel Chancellor, vice president of thought leadership at Norstella. "It wouldn't be sensationalist to suggest that China will overtake the U.S. in the next few years purely in terms of numbers of drugs that it's bringing through into its pipeline.' Bloomberg News' data analysis focuses on innovative drugs, excluding generic combinations, reformulations and biosimilars. Numbers aside, the more stunning leap is in the quality of Chinese biotech innovation. While there's constant debate in the pharmaceutical industry on whether Chinese firms are capable of producing not just effective but needle-shifting new therapies, there's growing recognition on multiple fronts. The world's strictest regulatory agencies, including the U.S. Food and Drug Administration and the European Medicines Agency, increasingly view Chinese drugs as generally promising enough to justify devoting extra resources to speed up their review, handing them coveted industry designations such as priority review, breakthrough therapy designation or fast track status. The country is now slightly ahead of the EU in earning such expedited reviews as of 2024, the data shows, a remarkable edge over a region that previously produced drugs like Wegovy. One of the early exemplars of Chinese innovation is a cell therapy that has shown promise to potentially cure a deadly blood cancer. First developed in China by Legend Biotech, it is now marketed by Johnson & Johnson — having won a few expedited review designations along the way — and considered superior to a competing U.S.-originated therapy. Still, the absolute number of China-originated drugs winning these designations trails their U.S. counterparts by a large margin. Risk aversion remains a factor holding back Chinese pharmaceutical innovation: So far, top companies tend to focus on making better versions of existing therapies or new iterations of older ideas, and few are pioneering novel treatment approaches that have never been tried before — an endeavor that comes with a high risk of failure and is still led by the U.S., Europe and, to a lesser extent, Japan. Nevertheless, the biggest Chinese breakthroughs are increasingly being snapped up by pharmaceutical giants for record sums, a sign that the perennial competition for the next blockbuster drug is also shifting East. A novel cancer drug from Akeso, which came out more effective than Merck & Co.'s Keytruda in a Chinese study last year, has been likened to China biotech's DeepSeek moment, spawning a new wave of global interest. The promise of topping Keytruda, the world's top-selling drug, also swelled the valuation of Summit Therapeutics, which in 2022 paid $500 million upfront for the development and marketing rights in the U.S. and other regions. Other multinational players like Merck, AstraZeneca and Roche Holding have also scooped up Chinese assets. In May, Pfizer set a new record as it announced a $1.2 billion upfront deal with 3SBio for a cancer drug similar to Akeso's. These deals are increasing in both value and frequency, according to biopharma deal database DealForma, signaling confidence that China-originated drugs are competitive internationally and can bring in substantial revenue. The volume of potential candidates coming out of China means multinational companies, which have a constant need to add new products to the mix, can "cast their net wider than ever before,' Norstella's Chancellor said. A key advantage that has fueled the rise of Chinese biotech firms is their ability to conduct research cheaper and faster at every step of the way, from lab experiments and animal testing to human trials. Technicians work inside a production laboratory for CAR-T cell therapies at an IASO Biotechnology facility in Nanjing on June 9. | Bloomberg Creating a new drug from scratch is notoriously time-consuming and expensive, and China's massive patient pool and centralized hospital network have become a significant accelerator. An analysis of the time taken for drugs to conduct various testing stages shows that doctors in China can recruit for trials much faster — for early trials for cancer and obesity drugs, they can complete patient enrollment in half the time compared to the U.S. The difference in costs means Chinese companies can afford to run multiple trials simultaneously to find a winner, or quickly launch new projects once a scientific idea is validated by other groups. Since 2021, China has become the top location for clinical research, initiating the largest number of new trials globally, according to GlobalData. "They can leapfrog competitors in other countries,' said Andy Liu, head of China at Novotech Health Holdings, which helps companies run clinical trials. To be sure, clinical data in China is just a start. U.S. regulators have made it clear that China-only trial results, no matter how positive, are not sufficient to support drug approvals. Chinese biotechs with ambition to sell their drugs overseas must prove that their treatment benefits can be replicated in non-Chinese patients, through complex and slower-moving global studies. It may still be a few years before a critical mass of drugs sourced from China wins U.S. and EU approvals — the gold standard for high-quality treatments — and becomes widely used in the Western world, but many in the industry believe that's inevitable. China's innovators comprise both cutting-edge biotech startups founded by foreign-educated entrepreneurs, and old-guard Chinese pharmaceutical companies like Jiangsu Hengrui Pharmaceuticals, which used to be one of the country's biggest generic drugmakers. The company poured billions of dollars into shifting to innovative research and development after Beijing's campaign to lower generic drug prices made that sector less profitable. It's now the world's top-ranked pharmaceutical company for the number of new innovative drugs added to the research pipeline in the period of 2020-2024. Of the 50 companies that generated the highest number of innovative drug candidates between 2020 and 2024, 20 of them were Chinese, compared to five in the five years before. "As we move forward, the fact that there's high quality innovation in China in terms of biotech will no longer be a novelty,' said Ali Pashazadeh, founder and managing director of healthcare advisory firm Treehill Partners in London. "It'll just be an accepted part of the norm.' At a time when China and the U.S. are engaged in renewed geopolitical spats, the growth of China's biotech ecosystem is causing alarm among some American politicians and business leaders. A congressional commission warned that the U.S. risks losing its leadership position in yet another industry critical to national security. "Biotech is one of the forefronts of the U.S.-China tech rivalry,' said Jack Burnham, research analyst at the think tank Foundation for Defense of Democracies. In addition to economic implications and possible military applications of biotech, China's leverage on innovative therapies may be weaponized in a future conflict, he said, if Americans become dependent on those medicines. The perception of threat has spurred calls for the U.S. government to stymie China's biotech growth — through restrictions such as export controls on scientific equipment and barriers to investment — and boost the domestic biotech sector, including by changing the regulatory environment to emulate countries where clinical trials are run more quickly. Robert F. Kennedy, the U.S. Secretary of Health and Human Services, recently pledged to "Make American Biotech Accelerate.' Despite the risks of the newly combative relationship between the world's two biggest economies, Chinese drugmakers like Akeso have set their sights on bringing their therapies to developed Western markets. "The pharma industry is the best industry in the world,' Akeso CEO Michelle Xia said in an April interview. "At the end of the day, what we do benefits patients in China, in the U.S. and all around the world.'

G20 agenda eclipsed as Bessent skips South Africa meeting again
G20 agenda eclipsed as Bessent skips South Africa meeting again

Japan Times

timean hour ago

  • Japan Times

G20 agenda eclipsed as Bessent skips South Africa meeting again

For the second time this year, the world's most powerful finance ministers gather in South Africa without the presence of the U.S. Treasury secretary. Scott Bessent will skip the Group of 20 again this week, continuing a boycott of South Africa by top U.S. officials begun by Secretary of State Marco Rubio, who stayed away out of scorn over his hosts' theme for its G20 presidency of "Solidarity, Equality and Sustainability.' South Africa is the first nation from the continent to host the G20. But its ambition to use that to advance issues vital for developing nations is likely to be further sidelined as the club confronts the latest salvo in U.S. President Donald Trump's trade war. "The challenge around the G20 is that you just don't know what is going to come out of the White House,' said Sanusha Naidu, senior research fellow at the Pretoria-based Institute for Global Dialogue. "There is an actor in the international system who is playing such a disruptive role for the order of global international governance.' The preeminent forum for multilateral cooperation has been under assault since Trump returned to the White House, hampering progress on issues including climate change and debt relief that South Africa hoped to promote. This meeting, held at the Indian Ocean resort of Zimbali near the port city of Durban on the country's southeast coast, faces the same fate. In addition to Trump's threat of crippling levies on key trading partners from Aug. 1, the U.S. president has taken aim at the BRICS bloc of emerging economies — which includes South Africa — threatening an extra 10% tariff for "anti-American' policies. He's also singled out Brazil, a member of both BRICS and the G20, promising a 50% tariff on the nation as he criticized its prosecution of former President Jair Bolsonaro for attempting to overturn the results of an election he lost. South African President Cyril Ramaphosa was the first BRICS leader to take on Trump after a meeting in Rio de Janeiro last week, saying the American president needed a "greater appreciation of the emergence of various centers of power in the world.' That came several weeks after he endured Trump berating him in a televised Oval Office meeting over false claims that his government was ignoring a genocide of the nation's white farmers. Ramaphosa is also still trying to convince Trump to attend a G20 leaders summit in Johannesburg in November, where he is due to hand over the presidency of the group to the U.S. The prospects that Trump would help advance South Africa's G20 priorities looks slim. "For a lot of the agenda that has been built up over the last four or five years, it's not fertile ground next year,' said Elizabeth Sidiropoulos, chief executive officer of the South African Institute of International Affairs, referring to climate finance and sustainability. Despite Washington's indifference, South Africa is sticking to its guns and will try to salvage what it can from the meeting, which runs all week and will be headlined by finance chiefs and central bank governors on Thursday and Friday. "Africa's development must remain front and center this year and into the future,' Ronald Lamola, South Africa's international relations minister, told a United Nations conference in Spain this month. "The world cannot stand by and watch as rising debt-service costs crowd out development for a generation.' One consequence of the U.S. skipping the meetings is that it's pushed some members of the so-called Global South and the U.S.'s traditional allies closer together. Shortly after Rubio's snub the European Union said it supported South Africa's G20 aims. Two weeks later, the economic bloc, which had been bickering with Pretoria over a range of issues, held its first summit with the nation since 2018. Trump "will not render the G20 irrelevant,' said Louw Nel, a senior political analyst at Oxford Economics Africa. "Countries are already starting to look beyond the Trump presidency and know these multilateral institutions will outlive this administration.'

Japan summer budgets grow, but so does spending gap
Japan summer budgets grow, but so does spending gap

NHK

time2 hours ago

  • NHK

Japan summer budgets grow, but so does spending gap

A new survey shows that people in Japan are gearing up for big spending this summer, with the average amount set aside for the holidays reaching a record. But there's also a growing gap between those splashing out and those cutting back. Major life insurer Meiji Yasuda held the survey in early June. Over 1,000 people from their 20s to their 50s responded. It shows that the average household budget for summer vacation grew 26.4 percent from last year. The figure reached nearly 105,000 yen, or over 710 dollars. It marks the fourth increase in a row and the first time the sum has surpassed 100,000 yen since 2006. The numbers show that 18.5 percent of respondents said they plan to boost summer holiday spending. As for the reasons, nearly three quarters said they wanted to travel, and over a quarter cited higher pay. But not everyone is increasing their budgets, as 18.3 percent said they are cutting back. More than 60 percent said soaring prices are squeezing finances. Almost a quarter said they are saving cash amid an uncertain outlook.

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