Vertex to stop developing new painkiller as solo treatment after mid-stage study setback
The next-generation drug, called VX-993, was found to be generally safe when tested in patients who had a bunion surgery, with most side effects being mild to moderate and no serious problems linked to the painkiller, the company said.
Wall Street analysts and investors have been eagerly awaiting the results of this trial that would help Vertex expand beyond its non-opioid Journavx, bolstering its pain drug treatments.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
The Independent
16 minutes ago
- The Independent
Health warning issued as source of serious bacteria outbreak revealed
Public health officials have issued a warning regarding an outbreak of Campylobacter and E. coli linked to raw milk from an unnamed farm in Florida. The outbreak has affected 21 individuals, including six children under 10, resulting in seven hospitalisations and two severe complications. The Florida Department of Health expressed concerns about sanitation practices at the implicated farm, noting that raw milk is only legally sold for non-human consumption in the state. Federal health agencies, including the CDC and FDA, strongly advise against consuming raw milk due to significant health risks from various pathogens, emphasising that pasteurisation eliminates these dangers. Despite scientific consensus on the risks, raw milk has gained popularity among some groups, with Health and Human Services Secretary Robert F. Kennedy Jr. being a consumer, though his administration has not delivered the regulatory changes raw milk advocates hoped for.
Daily Mail
17 minutes ago
- Daily Mail
Stomach-churning moment brown SEWAGE explodes from ceiling at America's busiest airport
Disgusting video appears to show sewage water leaking from the ceiling of America's busiest airport on Monday. The stomach-churning footage, taken by Jamaal Carlos Jr., shows the murky water exploding through a ceiling panel at Hartsfield-Jackson Atlanta International Airport. The gushing water stunned travelers who were trying to pass through the terminal. Some even seemed to cover their noses in a desperate attempt to shield themselves from the putrid smell. Carlos Jr. told 11 Alive the incident happened while he was waiting for his delayed flight from Atlanta, Georgia to Dallas, Texas. 'As we're waiting, we see water just pouring from the ceiling. It had been pouring consistently for maybe 10 to 15 seconds,' he recounted. 'And it just progressively got worse. The ceiling fell through and it stinks so bad.' He added that he saw debris falling from the ceiling, and claimed it took about five to 10 minutes for crews to respond and rope off the area with yellow caution tape. 'Even after it poured... I thought they would get buckets or do something, but people were walking through it,' Carlos said. Eventually, airport officials rerouted everyone in an effort to avoid the area, and the Lower North Checkpoint was temporarily closed, according to Fox 5. 'It's crazy,' Carlos said. 'So they moved our gate... we were just so close to it, so they moved us a little bit further, but you could still smell it two or three gates down.' Airport officials say they are now investigating what may have caused the leak. 'The affected area has been contained and remediation crews are actively working to clean and sanitize the space,' a spokesperson for the airport told 11 Alive. He added that customer service representatives are rerouting passengers around the area 'to ensure minimal disruption' and emergency medical crews were deployed as a precaution. 'There is no impact to overall airport operations,' the spokesman said.
Daily Mail
17 minutes ago
- Daily Mail
Trump's new NASA boss wants to build a nuclear reactor on the MOON
New NASA Administrator Sean Duffy's first project will be an attempt to take American energy dominance to the moon. Duffy, who is also Secretary of Transportation and took the job as NASA Administrator after the White House shut out Elon Musk's preferred candidate, will announce plans to build a nuclear reactor on the moon this week. The Daily Mail has reached out to NASA and the White House for comment. In 2022, NASA announced plans to put a nuclear reactor on the moon by 2030 as part of a vision to turn the lunar body into an orbiting power station but Duffy wants an expedited, more definite timeline. The goal is for United States to outpace China in 'winning the second space race,' a source told Politico. Earlier this year, it was revealed China may team up with Russia in an attempt to build their own lunar nuclear reactor. Sure enough, Duffy's directive claims that China or Russia or any American enemy could 'declare a keep-out zone which would significantly inhibit the United States' if they got to the moon first. Duffy's directive commands NASA to get someone to lead the effort in the next 60 days and solicit companies that can help launch ahead of China. A former Fox News and reality TV star, Duffy is also pushing an effort to replace the International Space Station. Duffy, a former Congressman from Wisconsin, oversees the $25 billion space agency. In 2022, the US space agency chose three design concept proposals for a fission power system that could be ready to launch by the end of the decade. It is unclear if Duffy is going from the same plans. The plan is for the 40-kilowatt class fission power system to last at least 10 years in the lunar environment, with the hope that it could one day support a permanent human presence on the moon, as well as support manned missions to Mars and beyond. If NASA is to build a base on the lunar surface, one of the major problems to solve will be how such a proposed settlement would be powered. Solar panels are great for powering rovers, but a human base would need a continuous and reliable source of power. NASA experts are looking into nuclear fission as the answer because the technology has been used extensively on Earth. Relatively small and lightweight compared to other power systems, fission systems are reliable and could enable continuous power regardless of location, available sunlight, and other natural environmental conditions, the US space agency said. If the demonstration of such a system on the moon was successful, it would pave the way for the fueling of longer duration journeys through space. It is hoped that the development of these fission surface power technologies will also help NASA advance nuclear propulsion systems that rely on reactors to generate power. These could then be used for deep space exploration missions. The goal will also be to beat China and Russia to the same mission. The East Asian country aims to become a major space power and land astronauts on the moon by 2030, and its planned Chang'e-8 mission for 2028 would lay the groundwork for constructing a permanent, manned lunar base. In a presentation in Shanghai, the 2028 mission's Chief Engineer Pei Zhaoyu showed that the lunar base's energy supply could also depend on large-scale solar arrays, and pipelines and cables for heating and electricity built on the moon's surface. Russia's space agency Roscosmos said last year it planned to build a nuclear reactor on the moon's surface with the China National Space Administration (CNSA) by 2035 to power the International Lunar Research Station (ILRS). The inclusion of the nuclear power unit in a Chinese space official's presentation at a conference for officials from the 17 countries and international organisations that make up the ILRS suggests Beijing supports the idea, although it has never formally announced it. 'An important question for the ILRS is power supply, and in this Russia has a natural advantage, when it comes to nuclear power plants, especially sending them into space, it leads the world, it is ahead of the United States,' Wu Weiren, chief designer of China's lunar exploration program, told Reuters on the sidelines of the conference. After little progress on talks over a space-based reactor in the past, 'I hope this time both countries can send a nuclear reactor to the moon,' Wu said.
