FDA names former pharmaceutical company executive to oversee US drug program
FDA Commissioner Marty Makary
announced that Dr. George Tidmarsh, a cancer and pediatric specialist, will direct the agency's Center for Drug Evaluation and Research, which regulates the safety and effectiveness of all U.S. drugs.
His appointment comes a month after the center's acting director, Dr. Jacqueline Corrigan-Curay, announced her retirement.
As the agency's top drug regulator, Tidmarsh will be charged with following through on a number of
commitments made by Makary
and his boss, Health Secretary Robert F. Kennedy Jr., including reviewing the
safety of the abortion pill mifepristone
. The FDA is also scrutinizing certain uses of other long-established drugs, including antidepressants and hormone-replacement drugs for menopause.
Tidmarsh founded and led several pharmaceutical companies, including Horizon Pharmaceuticals, maker of an anti-inflammatory medication for arthritis. He has also served as an adjunct professor at Stanford University.
The FDA's drug center is the agency's largest unit, with nearly 6,000 staffers responsible for reviewing the safety and effectiveness of new drugs and monitoring the use and marketing of older drugs.
About 2,000 FDA staffers have been laid off as part of widescale
cuts to the federal health workforce overseen by Kennedy
. More than 1,000 others have taken buyouts or early retirement, while many others are reportedly searching for new jobs. The departures have threatened basic FDA operations, including the timely review of new drugs.
FDA's drug center hasn't had a permanent director since January, when Dr. Patrizia Cavazzoni stepped down days before President Donald Trump took office.
Nearly all of the FDA's senior leadership positions have turned over in recent months, either due to retirements, resignations or actions by administration officials placing them on administrative leave.
FDA center directors typically hold their positions for years or even decades, serving across multiple administrations, whether Republican or Democrat.
In May, Makary named Dr. Vinay Prasad, a prominent
critic of the FDA's COVID response
, to run the agency's vaccine center. He was also named to the post of FDA chief medical officer. Prasad joined the agency after his predecessor, longtime vaccine chief Dr. Peter Marks,
was forced out in March
.
The
head of FDA's tobacco center was also forced to step down
in April. A permanent replacement has not yet been named.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.
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The ministry, part of the Hamas-run government, is staffed by medical professionals and its figures on war deaths are seen by the U.N. and other experts as the most reliable estimate of casualties. Salem Awad was born in January with no medical problems, the youngest of six children, his mother Hiyam Awad said. But she was too weak from lack of food to breastfeed him. For the first two months of Salem's life, there was a ceasefire in Gaza, and more aid entered, but even then it was hard to find milk for him, his mother said. In March, Israel cut off all food from entering the territory for more than 2 1/2 months. Since then, Salem has been wasting away. Now he weighs 4 kilograms (9 pounds), his mother said. 'He just keeps losing weight. At the hospital, they say if he doesn't get milk, he could die,' she said, speaking in the family's tent in Gaza City. Israel has been allowing a trickle of aid into Gaza since late May. After an international outcry over increasing starvation, it introduced new measures last weekend it says are intended to increase the amount of food getting to the population, including airdrops and pauses in military operations in some areas. But so far, they have not had a significant effect, aid groups say. Food experts warned this week the 'worst-case scenario of famine is playing out in Gaza.' The U.N. says the impact of hunger building for months is quickly worsening, especially in Gaza City and other parts of northern Gaza, where it estimates nearly one in five children is now acutely malnourished. Across Gaza, more than 5,000 children were diagnosed with malnutrition this month, though that is likely an undercount, the U.N. says. Malnutrition was virtually nonexistent before the war. Doctors struggle to treat the children because many supplies have run out, the U.N. says. Israel denies a famine is taking place or that children are starving . 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