High Protein In Urine: Is It Time To Screen For Chronic Kidney Disease?
Chronic Kidney Disease can move silently with little to no symptoms until months or even years
One of the most common red flag that doctors look out for is the presence of protein in the urine, as this could significantly deteriorate the kidneys. Chronic Kidney Disease (CKD) is a progressive illness that frequently goes unrecognized until significant kidney damage has already occurred. The Lancet states that CKD is present in approximately 10% of the adult population globally. Moreover, its incidence is on the rise due to the increasing rates of diabetes, hypertension, and unhealthy lifestyle habits. The effective way to manage CKD is through early detection and intervention.
Dr Nitin Shrivastava, Lead Consultant, Urologist, Manipal Hospital, Gurugram shares all you need to know:
What does protein in the urine indicate?
The presence of high levels of protein in the urine indicates the chances are that the kidneys are not functioning as well as they should. This is because protein and other important nutrients are easily able to pass through healthy kidneys and ultimately return to the blood. On the other hand, proteins like albumin leak through the kidney's filters and into the urine in case of dysfunction which is referred to as proteinuria or albuminuria and is among the first and most common signs of Chronic Kidney Disease (CKD). Other symptoms that may imply that the kidneys are not functioning properly include:
● Loss of appetite: Sudden or rapid weight loss without explanation can be attributed to the buildup of toxins in the body that the kidneys can no longer filter.
● Fatigue: Patients may experience a high level of fatigue or weakness and may even have difficulty sleeping. Cramping of muscles is also a common symptom.
● Changes in urination: Frequent urination or a reduced urge to urinate can both be pointing towards damaged kidney function and are often the earliest signs of trouble. It is typically at this stage that individuals decide to go for CKD screening.
● High blood pressure: Chronic conditions like hypertension and diabetes put individuals more at risk of developing kidney disorders. Additionally, impaired kidney function can make it difficult to keep blood pressure under control.
● Swelling in feet and ankles: The inability of kidneys to filter out excess fluid leads to retention, which develops as visible puffiness in the lower limbs.
Why does early screening matter?
Chronic Kidney Disease can move silently with little to no symptoms until months or even years. When individuals finally get tested, the kidneys have already been damaged significantly. In advanced stages, dialysis or a complete kidney transplantation (KTP) are needed to restore function. This involves surgically placing a healthy kidney from a living or deceased donor into the patient's body, offering a more permanent and effective solution in case of kidney failure.
The presence of protein in urine should never be ignored, as it may be the body's earliest warning of silent but progressive kidney damage. However, Regular screening is even more important for individuals with obesity, diabetes, hypertension, or a family history of kidney disease. A simple urine testing can become a life-saving intervention if timely action is taken to prevent further complications.
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First Published:
July 17, 2025, 18:11 IST
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