Jeito Capital Leads €132M Series to Advance Phase 3 Trials for Rare Neuro-Metabolic Disorders
Jeito Capital said it is leading a €132 million oversubscribed Series B funding round in Azafaros, a clinical-stage biotech company developing treatments for rare lysosomal storage disorders.
Azafaros, founded in 2018 and rooted in Dutch academic research, is advancing nizubaglustat, a first-in-class dual-acting drug targeting conditions like Niemann-Pick Type C and GM1/GM2 gangliosidoses, they said.
'Azafaros has the potential to develop new efficient, safe and tolerable therapeutic options for young patients suffering from progressive debilitating and even fatal rare metabolic disorders that generates very high expectations.' said Dr Rafaèle Tordjman, Founder and CEO of Jeito Capital. 'We look forward to supporting the talented Azafaros team with our collective expertise to accelerate its pivotal clinical developments to go faster to patients.'
Contact:
Exec Edge
Editor@executives-edge.com
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
14 hours ago
- Yahoo
When Will Ebusco Holding N.V. (AMS:EBUS) Breakeven?
We feel now is a pretty good time to analyse Ebusco Holding N.V.'s () business as it appears the company may be on the cusp of a considerable accomplishment. Ebusco Holding N.V., together with its subsidiaries, engages in the development, manufacture, and distribution of zero emission buses and charging systems. The €28m market-cap company announced a latest loss of €201m on 31 December 2024 for its most recent financial year result. Many investors are wondering about the rate at which Ebusco Holding will turn a profit, with the big question being 'when will the company breakeven?' We've put together a brief outline of industry analyst expectations for the company, its year of breakeven and its implied growth rate. This technology could replace computers: discover the 20 stocks are working to make quantum computing a reality. Ebusco Holding is bordering on breakeven, according to some Dutch Machinery analysts. They expect the company to post a final loss in 2025, before turning a profit of €12m in 2026. The company is therefore projected to breakeven just over a year from now. In order to meet this breakeven date, we calculated the rate at which the company must grow year-on-year. It turns out an average annual growth rate of 126% is expected, which is rather optimistic! Should the business grow at a slower rate, it will become profitable at a later date than expected. We're not going to go through company-specific developments for Ebusco Holding given that this is a high-level summary, but, keep in mind that by and large a high growth rate is not out of the ordinary, particularly when a company is in a period of investment. View our latest analysis for Ebusco Holding Before we wrap up, there's one issue worth mentioning. Ebusco Holding currently has a relatively high level of debt. Typically, debt shouldn't exceed 40% of your equity, which in Ebusco Holding's case is 71%. A higher level of debt requires more stringent capital management which increases the risk around investing in the loss-making company. Next Steps: There are too many aspects of Ebusco Holding to cover in one brief article, but the key fundamentals for the company can all be found in one place – Ebusco Holding's company page on Simply Wall St. We've also compiled a list of key aspects you should further research: Historical Track Record: What has Ebusco Holding's performance been like over the past? Go into more detail in the past track record analysis and take a look at the free visual representations of our analysis for more clarity. Management Team: An experienced management team on the helm increases our confidence in the business – take a look at who sits on Ebusco Holding's board and the CEO's background. Other High-Performing Stocks: Are there other stocks that provide better prospects with proven track records? Explore our free list of these great stocks here. Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Time Business News
2 days ago
- Time Business News
The Evolution of Clocks: From Sundials to Smart Timepieces
Timekeeping has been an integral part of human civilisation for millennia. From ancient shadows cast by stone markers to sleek smartwatches that sync with satellites, the evolution of clocks is a fascinating journey through innovation, culture, and craftsmanship. In today's world, while digital devices dominate our daily routines, traditional timekeeping instruments like analogue clocks still hold a special place for their classic charm and aesthetic appeal. The Origins: Sundials and Water Clocks The earliest known timekeepers were sundials, dating back to ancient Egypt around 1500 BCE. By observing the position of the sun's shadow, sundials divided the day into segments, allowing communities to regulate work, prayer, and social life. However, sundials were limited by the sun's availability – cloudy days or nightfall rendered them useless. To address this, civilisations like the Greeks and Chinese developed water clocks (also known as clepsydras), which used a controlled flow of water to measure time. These devices, although rudimentary, marked a turning point in creating timepieces that functioned independently of the sky. Mechanical Marvels of the Middle Ages With the rise of monasteries in medieval Europe, the need to schedule regular prayers led to innovations in mechanical clockmaking. Tower clocks powered by weights and gears began appearing in town squares during the 13th Century. Though not particularly accurate, they were monumental in both size and significance, offering the general public access to communal time for the first time. By the 14th and 15th centuries, advancements in escapement mechanisms allowed for more accurate and compact designs, leading to the creation of domestic clocks that could be housed within homes and workshops. The Age of Precision: Pendulums and Pocket Watches In 1656, Dutch scientist Christiaan Huygens introduced the pendulum clock, dramatically improving timekeeping precision. The use of swinging pendulums reduced time drift and became the gold standard in horology for over two centuries. Around the same time, the pocket watch emerged as a fashionable and functional accessory. Worn by aristocrats and commoners alike, these portable timepieces symbolised punctuality and personal organisation, cementing the idea that time was a possession one could carry. Industrial Innovation and Mass Production The 19th Century ushered in the industrial revolution, which transformed clockmaking from artisan craft to mass production. Factories in Europe and the United States produced thousands of affordable clocks, making them accessible to households across all social classes. This era also introduced standardised time zones, essential for scheduling trains and managing growing cities. Clocks became vital tools in both public infrastructure and private life. The Digital Shift and Quartz Revolution The 20th Century saw a major leap with the invention of quartz clocks in the 1920s. These timepieces used vibrating quartz crystals to maintain accuracy and eventually became the norm in homes, schools, and offices due to their reliability and low maintenance. In the 1970s, digital displays gained popularity, further transforming the aesthetics and function of timepieces. And yet despite the digital boom, traditional analogue clocks remained enduringly popular, thanks to their timeless elegance and intuitive readability. Today's Smart Timepieces Modern clocks have gone beyond simply telling time – smartwatches and smart clocks now monitor health, control home systems, and synchronise with devices globally in real-time. Powered by advanced algorithms and connected via the internet, today's smart timepieces are the epitome of convenience and multifunctionality. And yet, even in this high-tech age, people continue to embrace analogue timekeeping – whether for its nostalgic value, interior design appeal, or the tactile experience of watching hands glide across a clock face. A Matter of Time From sundials carved in stone to AI-powered smartwatches, the history of clocks reflects humanity's ongoing pursuit to organise, measure, and make the most of our time. Whether you prefer cutting-edge technology or the quiet dignity of analogue clocks, timekeeping remains both a practical necessity and a deeply human story. TIME BUSINESS NEWS
Yahoo
2 days ago
- Yahoo
Mistral in talks with VC firms, MGX to raise funds at $10 billion valuation, FT reports
(Reuters) -French artificial intelligence startup Mistral is in talks with investors, venture capital firms and Abu Dhabi's MGX to raise $1 billion at a valuation of $10 billion, the Financial Times reported on Friday, citing people familiar with the matter. The company launched in June Europe's first AI reasoning model, which uses logical thinking to create a response, as it tries to keep pace with American and Chinese rivals at the forefront of AI development. The funding would accelerate the commercial rollout of Mistral's Le Chat chatbot and support continued development of its large language models, the report said. MGX and Mistral did not immediately respond to Reuters requests for comment. The startup raised 600 million euros in a Series B funding round that valued the company at 5.8 billion euros last year. Industry observers consider Mistral as Europe's best-positioned AI company to rival Silicon Valley leaders, though the French firm has yet to achieve comparable market traction or revenue scale. Mistral counts Nvidia, Andreessen Horowitz and Lightspeed Venture Partners among its investors. Sign in to access your portfolio
