Hot sleeper? Here are 19 products that can keep you cool
If you wake up in a puddle: My Sheets Rock The Regulator Sheet Set
Like an AC for your head: Coop Sleep Goods The EdenCool+ Adjustable Pillow
For year-round comfort: Buffy Cloud Comforter
A fan for small spaces: Honeywell QuietSet Tower Fan
A mattress with customizable cooling: Helix Midnight Luxe Mattress Knowing how to stay cool while sleeping is the key to a good night's rest in the summer — and that's backed up by research. According to an analysis of data from over 3.75 million nights, sleep quality declines as temps climb above 60 degrees Fahrenheit. Not only did hot bedrooms lead to shorter sleep durations but it took participants longer to fall asleep in warmer rooms.
While air-conditioning seems like the most obvious solution, many Americans don't have central AC or can't afford their utility bills. Other folks simply run hot regardless of the temperature around them. That's why I spoke to five sleep experts to compile a list of the best cooling products and tips to help you avoid those sweaty, sleepless nights.
Casper Sleep Percale Sheet Set
Percale cotton is naturally breezy and breathable, making it a go-to fabric for sweaty sleepers. This set from Casper was our tester's choice for best cooling cotton sheets, as the sheets felt crisp to the touch and were airier than the others we tested.Read our review
Parachute Linen Sheet Set
Made from large, hollow flax fibers, linen fabrics promote airflow and wick moisture better than standard cotton sheets. This luxurious set from Parachute is no exception, with our testers describing them as cloudlike and elegant.Read our review
My Sheets Rock The Regulator Sheet Set
Chris Sun, the CEO and founder of My Sheets Rock, said The Regulator Sheets keep you 3 to 4 degrees cooler compared to polyester sheets, thanks to their 100% bamboo rayon construction. Contributing editor Marissa Miller confirmed their effectiveness in a hands-on review, describing them as "magically cooling and breathable in the summer."Read our review
Coop Sleep Goods The EdenCool+ Adjustable Pillow
The EdenCool+ is a game changer for hot sleepers and warm apartments, according CNN Underscored senior lifestyle editor Tamara Kraus and associate testing writer Carolina Gazal. The secret lies in its gel-infused adjustable filling, which cools on contact. Read our review
Pluto Pillow
The Pluto Pillow, the best pillow we've tested, has a distinct edge over other models we've reviewed because each one is personalized based on your sleeping habits. Hot sleepers can let their builder know they overheat at night, and Pluto will fit the pillow with cooling materials for sweat-free sleep.Read our review
Sijo FluffBase Eucalyptus Pillow
If you need to save some cash, Gazal points budget-conscious readers to this down-alternative model. On top of coming Oeko-Tex certified, it kept her cool throughout the night with its breathable 100% Tencel Lyocell fabric shell.Read our review
Luxome Lightweight Blanket
Falling soundly asleep while your home and bedroom are simmering at 80 degrees Fahrenheit sounds impossible. But with the help of this 100% bamboo rayon blanket, home and gifts editor Amina Lake Patel managed to do just that while she was living in a hot New York City apartment.Read our review
Slumber Cloud Ultra Cool Comforter
Deals editor Jacqueline Saguin reaches for this nylon and spandex comforter when she needs relief in the summer. If you order directly from SlumberCloud, you can choose from Lightweight and All-Season models, depending on your climate and cooling needs.Read our review
Buffy Cloud Comforter
This editor-favorite lightweight comforter is made with Tencel Lyocell, one of sleep expert Dr. Abhinav Singh's top recommendations for breathable bedding. Made from cellulose, it's a soft, breathable fabric that's more sustainable than modal and other semi-synthetic materials.Read our review
Bearaby Tree Napper
This weighted blanket also makes use of Tencel to regulate body temps as well as an open weave for improved breathability. It's perfect for anyone who needs the comfort of a weighted blanket when it's hot and humid.Read our review
Honeywell QuietSet Tower Fan
After testing 15 popular fans over four summer weeks, editor Suzanne Kattau decided that her favorite cooling fan was Honeywell's QuietSet Tower Fan. While it's compact and quiet, it still impressed with its cooling performance.Read our review
Dyson Cool AM07 Air Multiplier Bladeless Tower Fan
"In my last apartment, I wasn't able to control the heat or airflow, and relied on this Dyson fan to stay at an optimal temperature throughout the night," associate deals editor Elena Matarazzo said. In addition to its cooling power, she loves its easy-to-clean bladeless design, many speed settings and magnetized remote control.
LG 8,000-BTU LW8016ER Window Air Conditioner
A lot of apartments lack central air in Los Angeles and New York City, so tenants have to rely on less powerful window air conditioners. Luckily, our testers report that this model can cool a room from 80 degrees Fahrenheit to 68 degrees Fahrenheit in just one hour.Read our review
Rowenta Turbo Silence Extreme VU5670 Standing Fan
If you've got the space, pedestal fans often provide more cooling power and coverage. Despite its size, Rowenta's Turbo model earned top marks for its easy assembly and controls — not to mention its sturdy build.Read our review
Vornado 660AE Large Air Circulator Fan
During Kattau's rounds of testing, the Vornado 660AE came out on top as the best floor fan. Beyond its power and durable construction, it's also compatible with Alexa, making it ideal for smart home enthusiasts.Read our review
Helix Midnight Luxe Mattress
Don't know how to choose a mattress? Managing editor Rachel Quigley declared this one the best she's ever slept on after a month of testing. Though the base model comes with a cooling Tencel coating, you should pay for the extra heat-regulating materials.Read our review
Tuft & Needle Original Hybrid Mattress
Though the Tuft & Needle Hybrid failed to earn a top spot in our review of the best mattresses for back pain, tester Gabriella Triolo praised its temperature-regulating design, noting that her sleep had improved significantly by the third week. It is quite firm, however, so side sleepers may want to look elsewhere.Read our review
Sleep Number ClimateCool Premium Smart Bed
"No, it's not cheap, but sleeping on the ClimateCool has completely removed the threat of a sweaty night from my life," associate testing writer Joe Bloss said. "It makes the entire mattress feel like the other side of the pillow, with a programmable fan circulating air on your schedule and at your desired speed."Read our review The first thing you need to think about before choosing the best products for you is why you are getting overheated while you sleep. According to Chelsie Rohrscheib, a neuroscientist and head sleep researcher at Wesper, people get overheated 'due to a wide range of reasons,' from 'poor bedroom temperature control' and 'heavy bedding' to 'hormonal issues' and 'certain medications.' In other words, it's difficult to know exactly why you might be a hot sleeper, though it can help to scrutinize your bedroom setup and your medical history.
Once you have a little more information about the main problem areas, you can focus on the kinds of products that will help. For example, hot sleepers should choose loose, lightweight sleepwear and breathable bedding, opting for materials like bamboo, Tencel, linen and organic cotton, Singh said. 'Focus on breathability and moisture-wicking to regulate body temperature and prevent night sweats,' he added. 'Mattress toppers with adaptable cooling surfaces may be beneficial.'
Sun echoed Singh's advice, urging readers to try 'natural fibers that breathe better and won't trap heat like synthetics.' He recommends 100% bamboo rayon, which 'delivers both superior softness and exceptional cooling properties,' but cotton also works.
The following FAQs have been answered by My Sheets Rock CEO and founder Chris Sun; sleep specialist Dr. Abhinav Singh; neuroscientist and sleep researcher Chelsie Rohrscheib; Charlotte Gupta, a member of the Sleep Health Foundation and postdoctoral researcher at the Appleton Institute; and Joseph Dzierzewski, the senior vice president of research and scientific affairs at the National Sleep Foundation. The FAQs also include research and reporting by associate writer Maxwell Shukuya.
How do I stop being a hot sleeper?
How do I stop being a hot sleeper?
Regardless of the cause, Rohrscheib said there are a few things you can do to stop being a hot sleeper. The first step is to keep your bedroom cool, between 65 degrees Fahrenheit and 75 degrees Fahrenheit, according to Rohrscheib.
Beyond keeping your room chilly, you can also try to change your bedding, mattress and sleepwear. 'Always use bedding that is made of breathable, natural material such as linen, and consider using multiple thin blankets so you can remove a layer as needed,' Rohrscheib said, adding that cooling beds or mattress toppers can also help.
By the same token, Rohrscheib said to avoid overdressing for bed and wearing synthetic pajamas that could trap heat. The general approach should be to 'put time and effort into working out what your ideal sleeping environment is (e.g., investing in cooling sheets if that will help you get a good night sleep),' Gupta said.
But let's say your room is a cool 65 degrees Fahrenheit, you've got the best linen sheets and the best cooling fans blowing 24/7 and you're still hot at night. At that point, it's time to get help. 'If you're consistently waking up due to feeling hot or sweating, despite making some changes to bedding and clothing, there might be an underlying medical cause,' Dzierzewksi said. 'It is important to discuss your experiences with your health care professional.'
Is it unhealthy to sleep in a hot room?
Is it unhealthy to sleep in a hot room?
'Sleeping in a hot room may lead to insomnia and poor sleep quality, which can negatively impact your health,' said Rohrscheib, who explains that your body temperature has to drop by about 1 degree Fahrenheit to get to sleep. Gupta added that sleeping in a hot room over time can lead to 'chronic sleep loss,' which can then lead to 'increased physical and mental illness.'
'Typically, if we are not comfortable with the temperature as we are sleeping, we will have poor sleep quality, and this can occur even if we have our typical time in bed (e.g., we still have nine hours in bed, but our sleep quality is poor),' Gupta said. 'This is likely to happen in summer, and on individual occasions isn't too much of a risk … But over time, if we are consistently getting poor sleep, this is a problem.'
What temperature should my bedroom be at while sleeping?
What temperature should my bedroom be at while sleeping?
The best bedroom temperature for sleep is between 60 degrees Fahrenheit and 67 degrees Fahrenheit, according to Singh. 'This range supports the body's natural thermoregulation and supports the likelihood of more continuous uninterrupted sleep,' he said.
How do cooling blankets work?
How do cooling blankets work?
According to Sun, cooling blankets and bedding work by wicking moisture away so it can evaporate more quickly. 'This moisture-wicking ability, combined with the fabric's higher thermal conductivity compared to polyester or cotton, helps maintain a cooler, more consistent sleep environment,' he said.
Are hot flashes the same as being hot while sleeping?
Are hot flashes the same as being hot while sleeping?
No, they're not. Whereas hot flashes can make you hot, Singh said they're usually brief episodes of intense upper-body warmth related to menopause and can occur day or night. Meanwhile, if you sleep hot, you're someone who is too warm in bed, 'often due to environmental factors (room temperature, bedding), personal physiology or hormonal changes.'
What are some other ways to sleep without air-conditioning?
What are some other ways to sleep without air-conditioning?
Around 10% of households in the US don't have air-conditioning, according to a 2022 Brookings Institution report. Additionally, even if you are one of the many Americans that does have an air conditioner, not everyone can afford to run it day and night. Either way, the following tips can help you keep cool without an AC.
Drink water: Staying hydrated can help you beat the heat. The Institute of Medicine of the National Academies recommends that adult men and women drink 13 and nine cups of water a day, respectively.
Take a cold shower: A cold shower or bath before bed could cool you down, Gupta said, therefore facilitating a good night's sleep.
Use fans: While fans don't always lower a room's temperature, they can help you feel cooler by evaporating the sweat on your skin. Our favorite cooling fan is quiet, affordable and compact.
Sleep with an ice pack: Place an ice pack behind your neck or in bed to cool down your bed.
Cook in the morning: Help keep your house cool by cooking during the first part of the day.
Sleep in the basement: Heat rises, so you may find that the first floor of your house — or better yet, a basement — is coolest.
Look into government programs: See if your local government has any cooling centers, utility discounts or other assistance programs.
Invest in cooling products: Finally, consider investing in the above products, all of which should help you sleep cooler in the summer.
For this article, we consulted the following sleep experts for their professional insights.
Joseph Dzierzewski, senior vice president of research and scientific affairs at the National Sleep Foundation, who has a doctorate in clinical psychology
Charlotte Gupta, member of the Sleep Health Foundation and postdoctoral researcher at the Appleton Institute
Chelsie Rohrscheib, neuroscientist and head sleep researcher at Wesper
Dr. Abhinav Singh, fellow of the American Academy of Sleep Medicine, medical director at the Indiana Sleep Center and author of 'Sleep to Heal: 7 Simple Steps to Better Sleep'
Chris Sun, CEO and founder of My Sheets Rock
CNN Underscored has a team of skilled writers and editors who have many years of experience testing, researching and recommending products, and they ensure each article is carefully edited and products are properly vetted. We talk to top experts when applicable to make certain we are testing each product accurately, recommending only the best products and considering the pros and cons of each item. Here, writer Maxwell Shukuya pulled sleep products from CNN Underscored's vast library of reviews and spoke to five sleep experts to get their tips and recommendations to stay cool while sleeping.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
an hour ago
- Yahoo
Four new cases of measles in Fayette County; eight now tied to Central KY outbreak
The measles outbreak in Central Kentucky is growing. As of July 7, there were eight confirmed cases of the highly contagious measles virus connected to an outbreak in Woodford and Fayette counties, Lexington-Fayette County Health Department officials said Monday. That includes four new cases in Fayette County, all of which are tied to the first Fayette County case. Those who got the virus were considered household contacts. 'These individuals have been under quarantine since the initial case was identified, and there is no known additional risk to the public from these cases,' health officials said in a Monday news release. In addition to the Central Kentucky outbreak, an unrelated measles case was confirmed in Todd County on June 27. In total, Kentucky has reported 11 measles cases in 2025. The Lexington-Fayette County Health Department is continuing to respond to the outbreak. The health department continues to work closely with the Kentucky Department for Public Health and other local partners to investigate cases, ensure appropriate quarantine protocols and notify those who may have been exposed. In a previous Herald-Leader article, Kentucky Health and Family Services Secretary Dr. Steven Stack described the spread as 'not surprising' given the wider measles outbreak across the country. This year, the U.S. Centers for Disease Control and Prevention has reported more than 1,200 measles cases across multiple states. The department is encouraging everyone to verify their vaccination status and ensure they are protected. The measles, mumps, and rubella (MMR) vaccine is a safe and effective way to prevent infection. Adults born after 1957 should have documentation of at least one dose of MMR vaccine, and children should receive two doses: the first at 12-15 months and the second at 4-6 years of age.
Medscape
an hour ago
- Medscape
Could EMR Alerts Boost Hypertension Detection?
Could a simple advisory or alert in the electronic medical record (EMR) be the key to more frequent diagnosis and effective treatment of high blood pressure (BP)? While it could help, some physicians say it's not sufficient to solve the persistent problem of hypertension. However, such alerts could be part of an effective approach to catching more cases of hypertension and helping people manage their high BP. Tackling High BP Hypertension is well-known as a 'silent killer.' Left untreated, it raises the risk for heart attack, stroke, and other life-threatening events without causing any symptoms. Hypertension is also a widespread problem. The CDC estimates that about 120 million adults in the US have high BP, defined as having a systolic BP higher than 130 mm Hg or a diastolic BP greater than 80 mm Hg (or taking medication to lower their BP). However, only about 1 in 4 adults with high BP actually have their BP under control. According to the results of a recent quality improvement study in JAMA Network Open , using technology to prompt team-based care can improve primary care hypertension control and diagnosis in the ambulatory setting. The researchers tested an intervention consisting of a high BP advisory in the EMR, along with team training, audit, and feedback. If an elevated BP reading (systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg) was entered into the EMR, the medical assistant received an advisory to recheck the patient's BP. If the BP continued to be elevated, the EMR prompted a clinician-facing advisory, along with an order panel link. 'This study demonstrates that a paired human-technology intervention focused on team-based care and EMR integration is a fruitful approach to improving population health metrics,' the authors wrote. 'Anything that is done to alert the clinician is appropriate because of clinical inertia,' said Luke Laffin, MD, co-director of the Cleveland Clinic's Center for Blood Pressure Disorders in Cleveland, Ohio. 'There's a lot of clinical inertia in hypertension care. It breaks that inertia. I'm not surprised that this intervention works.' The Value of an Alert The idea of incorporating this type of alert into the EMR system is feasible, according to Brian Barr, MD, cardiologist at the University of Maryland Medical Center and assistant professor of medicine at the University of Maryland School of Medicine in Baltimore. 'Most modern EMRs — such as Epic, Cerner, Athenahealth, and others — are equipped with customizable clinical support tools that allow for automated reminders, alerts, and health maintenance prompts,' Barr said, adding that configurations could allow for notifications for missing BP readings or lack of documentation of BP within a particular time period. Alerts could also be quite useful to busy primary care physicians who see patients for a multitude of reasons. 'It's a reminder not to get distracted by the chief complaint syndrome,' said Brent Smith, MD, a family physician in Greenville, Mississippi and member of the board of directors for the American Academy of Family Physicians. 'It forces us not to overlook hypertension when there are other things that brought them into the doctor's office.' Using this type of tool could also identify patients with multiple elevated BP readings but no formal hypertension diagnosis, said Barr. That information could also allow physicians to follow patients more closely and confirm elevated BP in multiple settings — not just in the office, according to Blair Suter, MD, cardiologist with The Ohio State University Wexner Medical Center. 'It could be the canary in the coal mine,' he said. 'It could really be the sign of things to come or to progress to.' However, healthcare organizations must also be cautious about the possibility of contributing to electronic health record alert fatigue and instead find a balance that allows the use of technology to improve patient care without increasing the alert burden on clinicians. The authors of the study also acknowledged that some clinic managers had sustainability concerns about the time needed for BP rechecks. '[A]fter the rollout, some clinics piloted scheduling patients 10 minutes ahead of the clinician visit to increase previsit time for [medical assistants] to manage this and other population health initiatives,' they wrote. 'I think that rather than just having alerts, where people tend to get alarm fatigue, it might be more useful to focus on how we're collecting the data and how reliable it is and how much of a true reflection it is of the patient's true blood pressure when they're not in the office,' said Jeremy Bock, MD, interventional cardiologist and endovascular specialist at VHC Health in Arlington, Virginia. At-Home Monitoring Indeed, even if alerts do help, the challenge of getting patients to monitor their BP regularly at home does persist. At-home checks can seem nonurgent to them, especially if they are already taking an antihypertensive medication and feel fine. Kristen Trom, DO, family physician with Inspira Health in Mullica Hill, New Jersey, said that her organization's EMR uses an alert, but it's still a challenge to get patients to monitor their BP at home and take their medication. 'Resistance to starting medication can be a major challenge,' she said. 'Many of these patients have never been on medication before and prefer not to start.' 'It's trying to find that balance between being nonintrusive and also being part of their daily routine,' said Laffin. Physicians may need to spend more time emphasizing the importance of at-home BP monitoring and ensure patients know how to do it correctly. Prevention efforts can be time-consuming, noted Bock, but they can also improve patient-provider relationships and patient satisfaction. One important element of that process is reminding patients to use a validated BP cuff. Suter recommends directing patients to the website which is also suggested by the American Heart Association. Future Possibilities Time is often the biggest impediment for primary care providers. Eventually EMRs may be configured — along with AI — to incorporate the most effective cues and advisories, and then filter the information that would be most helpful for the physician, Smith said. 'It is getting better, and it has potential for the future,' he said. Barr added that other efforts could bolster such improvements. For example, clinic-level interventions also play a major role. 'Standardized blood pressure measurement protocols, routine use of home blood pressure monitoring, automated follow-up scheduling, and nurse-led hypertension visits can all support timely diagnosis and management,' Barr said. 'Engaging patients through portal alerts, educational messaging, and self-reported blood pressure entries adds another layer of protective care. Together, these strategies help close care gaps and support earlier identification and treatment of hypertension, ultimately improving long-term cardiovascular outcomes.'
Yahoo
an hour ago
- Yahoo
Basilea receives USD 39 million funding under BARDA agreement to continue to advance novel antifungals fosmanogepix and BAL2062
Ad hoc announcement pursuant to Art. 53 LR Allschwil, Switzerland, July 08, 2025 Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today that the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services, committed the next USD 39 million to Basilea to continue to advance the development of Basilea's novel antifungals fosmanogepix and BAL2062. This additional funding is based on the successful completion of a milestone within the 'Other Transaction Agreement' (OTA, agreement number 75A50124C00033) that was awarded on September 30, 2024, and which allows for potential funding of up to approximately USD 268 million in total to develop antifungal and antibacterial assets. David Veitch, Chief Executive Officer of Basilea, said: 'We are very pleased to receive the continued funding under the OTA with BARDA to support the development of our antifungal drug candidates fosmanogepix and BAL2062. Both compounds offer a novel mechanism of action and represent new therapeutic options for patients with aspergillosis, candidiasis or other life-threatening fungal infections. These infections primarily affect patients with weakened immune systems, such as cancer or transplant patients. Infections with difficult-to-treat rare molds or with resistance to current therapies are increasing. Hence, there continues to be a high medical need for new innovative antifungals.' He added: 'This second tranche of funding within the BARDA OTA will support the ongoing phase 3 study with fosmanogepix in yeast infections and the second phase 3 study, in mold infections, which is expected to start soon. It also provides funding for the preparation for the start of the phase 2 study for our antifungal BAL2062.' The USD 39 million is in addition to the initial USD 29 million BARDA committed at the signing of the OTA in September 2024. BARDA's financial contribution is about 60% of the total costs of the supported projects over the term of the OTA, which could provide a total potential non-dilutive funding of up to approximately USD 268 million, over up to 12 years, if all additional options to extend the contract are exercised by BARDA, upon successful completion of pre-defined milestones, including clinical and regulatory activities. About fosmanogepix Fosmanogepix is a clinical-stage broad-spectrum antifungal. It has a novel mechanism of action and its active moiety has shown activity against common species of Candida and Aspergillus, including multi-drug-resistant strains, such as Candida auris and Candida glabrata, as well as rare difficult-to-treat molds including Fusarium spp., Scedosporium spp., and some fungi from the Mucorales order.1 Fosmanogepix intravenous and oral formulations have been evaluated in clinical phase 2 studies for the treatment of patients with Candidemia, including Candida auris infections, and invasive mold infections.1 A phase 3 study evaluating fosmanogepix in the treatment of adult patients with candidemia and/or invasive candidiasis is ongoing and the initiation of a second phase 3 study, in the treatment of adult patients with invasive mold infections, is expected soon.2 Fosmanogepix has received Fast Track and Orphan Drug designations from the U.S. Food and Drug Administration for a number of indications, and is designated as a Qualified Infectious Disease Product (QIDP). About BAL2062 BAL2062 is a first-in-class antifungal, derived from a natural product, and has demonstrated fungicidal activity against clinically important molds such as Aspergillus spp., including azole-resistant strains.3 Safety and tolerability have been demonstrated in a previously completed phase 1 study with single and multiple ascending intravenous (i.v.) doses.4 The drug candidate has Qualified Infectious Disease Product (QIDP), Orphan Drug and Fast Track designation from the US Food and Drug Administration (FDA) for invasive aspergillosis. About invasive mold infections Invasive aspergillosis and invasive infections with rare molds (e.g., Fusarium spp., Scedosporium spp., and Mucorales fungi) are life-threatening infections that predominantly affect immunocompromised patients, including patients with hematologic malignancies (blood cancer), transplant patients, or patients with other immunodeficiency disorders. These infections are associated with high morbidity and mortality.5, 6 About invasive candidiasis Invasive candidiasis, including deep-seated tissue candidiasis and candidemia, is an increasingly important nosocomial infection, especially in patients hospitalized in intensive care units. Candida species are ranked as the fourth main cause of bloodstream infections in hospitals in the US.7 The prognosis of invasive candidiasis remains difficult, with a reported mortality rate for invasive candidiasis as high as 40%, even when patients receive antifungal therapy.8 About Basilea Basilea is a commercial-stage biopharmaceutical company founded in 2000 and headquartered in Switzerland. We are committed to discovering, developing and commercializing innovative drugs to meet the needs of patients with severe bacterial and fungal infections. We have successfully launched two hospital brands, Cresemba for the treatment of invasive fungal infections and Zevtera for the treatment of bacterial infections. In addition, we have preclinical and clinical anti-infective assets in our portfolio. Basilea is listed on the SIX Swiss Exchange (SIX: BSLN). Please visit Disclaimer This communication expressly or implicitly contains certain forward-looking statements, such as "believe", "assume", "expect", "forecast", "project", "may", "could", "might", "will" or similar expressions concerning Basilea Pharmaceutica Ltd, Allschwil and its business, including with respect to the progress, timing and completion of research, development and clinical studies for product candidates. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of Basilea Pharmaceutica Ltd, Allschwil to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Basilea Pharmaceutica Ltd, Allschwil is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise. This project has been funded in part with federal funds from the U.S. Department of Health and Human Services (HHS); Administration for Strategic Preparedness and Response (ASPR); Biomedical Advanced Research and Development Authority (BARDA), under OT number: 75A50124C00033. The contract and federal funding are not an endorsement of the study results, product, or company. For further information, please contact: Peer Nils Schröder, PhD Head of Corporate Communications & Investor RelationsBasilea Pharmaceutica International Ltd, Allschwil Hegenheimermattweg 167b4123 AllschwilSwitzerland Phone +41 61 606 1102 E-mail media_relations@ This ad hoc announcement can be downloaded from References K. J. Shaw, A. S. Ibrahim. Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections. Journal of Fungi (Basel) 2020 (6), 239 FAST study (candidemia/invasive candidiasis): identifier NCT05421858; FORWARD study (invasive mold infections): identifier NCT06925321 K. J. Shaw. GR-2397: Review of the Novel Siderophore-like Antifungal Agent for the Treatment of Invasive Aspergillosis. Journal of Fungi (Basel) 2022 (8), 909 identifier NCT02956499: M. P. Mammen, D. Armas, F. H. Hughes et al. First-in-Human Phase 1 Study To Assess Safety, Tolerability, and Pharmacokinetics of a Novel Antifungal Drug, VL-2397, in Healthy Adults. Antimicrobial Agents and Chemotherapy 2019 (63), e00969-19 J. Cadena, G. R. Thompson 3rd, T. F. Patterson. Aspergillosis: Epidemiology, Diagnosis, and Treatment. Infectious Disease Clinics of North America 2021 (35), 415-434 M. Slavin, S. van Hal, T. C. Sorrell et al. Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality. Clinical Microbiology and Infection 2015 (21), 490.e1-490.e10 Candidemia (Blood Infection) and Other Candida Infections. 2019 Factsheet by the American Thoracic Society: (Accessed: July 07, 2025) B. J. Kullberg, M. C. Arendrup. Invasive Candidiasis. The New England Journal of Medicine 2015 (373), 1445-1456 Attachment Press release (PDF)
