
Calicut University researchers develop LED tech using gold-copper alloy nanoclusters
MALAPPURAM: Researchers at the University of Calicut have made a significant breakthrough in next-generation light-emitting diode (LED) technology by engineering an innovative LED device using gold-copper alloy nanoclusters.
The cutting-edge research, spearheaded by Dr Shibu Sidharth and his PhD student Dr Rival Jose from the Department of Nanoscience and Technology, has resulted in the creation of a nanocluster-based LED (NC-LED) that delivers a saturated pure red emission with an external quantum efficiency (EQE) of 12.6%—among the highest ever recorded for its class.
This remarkable discovery has been published in Advanced Materials (Wiley), a globally acclaimed journal in materials science with an impact factor of 27.4. This marks the first time a research article from the University of Calicut has appeared in such a high-impact journal, cementing the institution's rising stature in global scientific research.
The innovation centres on atomically precise nanoclusters made of a few metal atoms -- specifically, a gold-copper (Au-Cu) alloy. These tiny clusters, although invisible to the naked eye, exhibit extraordinary photophysical properties such as intense light emission, high thermal and photostability, and strong environmental compatibility.
Unlike conventional LEDs, this new device does not rely on toxic or expensive materials and is fabricated through a simple, solution-processed, and eco-friendly method -- making it both sustainable and scalable.
Dr Shibu Sidharth, the lead researcher, emphasised the dual significance of this work: 'Not only have we pushed the frontier in nanocluster-based LED efficiency, but we've also demonstrated that high-impact innovations can emerge from Indian state universities. This is a proud moment for the University of Calicut and for India.'
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


The Hindu
an hour ago
- The Hindu
Large genetic map of Indians flags hidden disease risks
India's vast linguistic, cultural, and social diversity has long been evident, but only now are scientists beginning to uncover the genetic richness underpinning it. In a new study in Cell, researchers reported sequencing the genomes of 2,762 Indians from 23 States and Union Territories. The data captured variation across caste, tribal groups, language, geography, and rural-to-urban settings, offering the most comprehensive genomic map of India to date. The findings are striking. The study reaffirmed the three primary sources of Indian ancestry and explored how this layered history, along with entrenched social practices, continues to shape health and disease risk today. One migration, many mixtures Using mutations as genetic clocks, the study confirmed that present-day Indians descend primarily from a single out-of-Africa migration around 50,000 years ago. Although archaeology suggests earlier human presence in the subcontinent, 'those populations may not have survived or left lasting genetic traces,' said Elise Kerdoncuff, the study's first author. The researchers modelled Indian ancestry as a blend of three ancient populations: indigenous hunter-gatherers known as Ancient Ancestral South Indians; Iranian-related Neolithic farmers, best represented by fourth millennium BC herders from Sarazm in present-day Tajikistan; and Eurasian Steppe pastoralists, who arrived around 2000 BC and are associated with the spread of Indo-European languages. While most Indians fall along a genetic spectrum reflecting different proportions of this admixture, individuals from East and Northeast India, and a subset from Central India, carry additional East Asian-related ancestry, with levels reaching up to 5% in West Bengal. This likely entered around 520 AD, after the Gupta Empire's decline or with an earlier spread of rice farming. Legacy of endogamy, kinship India's population structure reflects long-standing practices of marriage within communities. This has produced strong founder effects, where a small ancestral gene pool gets amplified over generations. As a result, Indians, especially in South India, have 2-9x more homozygosity than Europeans or East Asians, making them more likely to inherit the same version of a gene from both parents. Every individual in the study had at least one genetic relative, indicating levels of relatedness far exceeding those seen elsewhere. This tight-knit structure may make recessive disorders caused by inheriting faulty copies of the same gene from both parents more common than currently recognised. One example is a pathogenic BCHE variant linked to severe anaesthetic reactions found enriched in Telangana. Like all non-Africans, Indians carry traces of ancient interbreeding with other hominins, with Neanderthal or Denisovan segments covering up to 1.5% of the genome in some Indians. They also have the widest variety of Neanderthal segments. 'Multiple waves of migration, followed by caste-based endogamy, likely fixed archaic segments within specific groups, contributing to this high diversity,' Lomous Kumar, population geneticist at the Centre for Anthropobiology and Genomics of Toulouse, France, said. Neanderthal-derived sequences are enriched in immune system genes. A region on chromosome 3 (linked to severe COVID-19) is especially common in East and Northeast India. Denisovan variants appear in immune-related pathways and regions such as the MHC, a key genomic region involved in detecting and fighting infections. 'Enrichments in TRIM and BTNL2, involved in mounting immune responses to viruses, suggests that some variants were retained because they conferred an adaptive advantage,' Dr. Kerdoncuff said. 'As humans moved into new environments, inheriting these variations from archaic populations likely helped them adapt to unfamiliar pathogens.' Only a part of the story The researchers uncovered 2.6 crore undocumented genetic variants. Of these, over 1.6 lakh were protein-altering variants absent from global databases and about 7% were linked to thalassemia, congenital deafness, cystic fibrosis, and metabolic disorders. 'This highlights how neglected Indians are in genomic surveys,' Dr. Kerdoncuff said, 'limiting scientific discovery and reducing the accuracy of risk predictions. The promise of precision medicine for underrepresented populations ultimately suffers.' Dr. Kumar added: 'Within India as well, population-specific rare and unique variants continue to make the scenario complex,' emphasising localised efforts are also imperative. To help close this gap, Dr. Kerdoncuff said, the team is expanding the study to include more genetically isolated communities. They're also studying proteins and metabolism to better understand how genes influence health outcomes. In parallel, they're developing new tools to trace the origins of disease-linked genes in Indian populations. To make medicine truly inclusive, India's vast genetic diversity must be central to global research and matched by deeper, community-level efforts at home. Anirban Mukhopadhyay is a geneticist by training and science communicator from Delhi.


The Hindu
an hour ago
- The Hindu
Kombucha can rebalance gut ecosystem in people with obesity: study
From Instagram reels to supermarket shelves, kombucha — the fizzy, fermented tea drink — has found a growing audience among health-conscious consumers in India. Promoted as a probiotic powerhouse, it's touted for its supposed benefits to digestion, immunity, and metabolism. According to one estimate provided by Indian company Sbooch, the kombucha market in India grew from $45 million in 2020 to $102 million in 2024. Yet much of the enthusiasm has outpaced science. While kombucha's traditional use and composition suggest potential health benefits, few rigorous studies have tested these claims in humans. Most research until now has focused on kombucha's biochemistry or has been limited to animal models. This is why a recent study in The Journal of Nutrition stands out: it takes a closer look at kombucha's effects on the human gut microbiome and how they matter for human health. The study followed 46 healthy adults in Brazil — 23 with obesity and 23 of normal weight — over eight weeks in a pre-post trial. The participants were classified using (World Health Organisation cut-offs of) BMI and waist circumference. Every day, each participant consumed 200 ml of kombucha that had been prepared in the lab using black tea and fermented with a symbiotic culture of bacteria and yeast (SCOBY). All participants were otherwise healthy and had no recent history of drugs, antibiotics or supplements. Stool samples were collected at the beginning and end to assess gut microbiome changes. The researchers used genomic tools to profile bacterial and fungal communities. They also measured fasting blood glucose, insulin, and proteins linked to gut barrier integrity since a weakened gut lining can allow harmful molecules to enter the bloodstream, trigger low-grade inflammation, and ultimately engender insulin resistance. What we know, what changed After eight weeks, the overall microbial diversity was largely unchanged but the abundance of certain bacteria had changed in ways that suggested kombucha may help positively rebalance the gut ecosystem. Notably, the population of Akkermansiaceae bacteria had increased in individuals with obesity. Previous research has linked this shift with better blood sugar control and insulin sensitivity. The levels of Prevotellaceae also increased, specifically in the obese group. Certain strains of Prevotella copri have similarly been linked to improved insulin sensitivity, hypertension, and inflammation. Both groups also reported higher abundance of Bacteroidota, which play significant roles in digesting complex carbohydrates. Bacteria associated with less favourable outcomes including Ruminococcus and Dorea declined, becoming similar to the normal-weight group by the eighth week. Ruminococcus gnavus has been positively associated with inflammatory bowel disease and liver fat accumulation, while Dorea with high BMI and cholesterol markers. In normal-weight participants, Parabacteroides increased modestly. Parabacteroides goldsteinii has been known to reduce tissue inflammation, ameliorating chronic obstructive pulmonary disease and Helicobacter pylori infections. The populations of Exophiala and Rhodotorula, two fungi associated with cystic fibrosis and obesity respectively, decreased as well. While the study offers promising clues about kombucha's influence, especially for individuals with obesity, the researchers urged caution. The microbial shifts were modest and didn't improve metabolic markers like blood glucose, insulin, or inflammatory proteins. The team also pointed out that microbial responses vary by diet, genetics, and overall health, thus reducing the generalisability of the findings. And with a short duration and a modest sample size, the findings remain a proof-of-concept. The results are still valuable in what they reveal, however: kombucha does appear to nudge the gut microbiome in directions associated with better metabolic health after two months. Kombucha and India Whether the effects will hold for Indian populations remains an open question. Studies have indicated gut microbiota in India are unique. Indian guts, particularly among those consuming traditional plant-based diets, harbour more Prevotella, an inversion of the typical Western microbial pattern. Since consuming kombucha increased Prevotellaceae abundance in the study, it may not drive the same degree of change in local populations. Even within India, while North Indians have more Prevotella, South Indians carry a higher load of Bacteroides and Ruminococcus. Women from rural high-altitude areas have greater gut diversity than their urban counterparts. Ethnic tribes from Ladakh, Jaisalmer, and Khargone can be differentiated based on their gut microbiomes alone. Taken together, the new study is proof that no single brand of kombucha can claim to be 'good' for all consumers across geographies. The drink may support gut health but whether that translates to long-term metabolic benefits remains to be seen. Anirban Mukhopadhyay is a geneticist by training and science communicator from Delhi.


Time of India
an hour ago
- Time of India
'You may be far, but hearts of 140cr Indians beat with you, it's start of new era': PM Modi to Shukla on ISS
NEW DELHI: 'Earth looks borderless and gives feeling of oneness, and Bharat looks big from space,' Indian astronaut Shubhanshu Shukla told PM Narendra Modi on Saturday during his first interaction with the PM through a video link from the International Space Station while 'orbiting Earth at an altitude of 400 km". Cheering the astronaut, Modi told him that 'you may be far from us but the hearts of 140 crore Indians beat with you'. 'The first thing I saw was Earth — it looks perfectly unified. No borders are visible. India looks so large from here, far more prominent than on a map. From up here, there are no countries, no divisions — just one home. That is our ethos: unity in diversity. Just a while ago, when I saw from the window of ISS, I could see Hawaii,' Group Captain Shukla told the PM while informing him, 'I have hoisted the tricolour on ISS. India has reached ISS. ' Modi said Shukla's name carries the word 'shubh' (meaning auspicious) and that his journey marked the auspicious 'beginning of a new era'. The Indian astronaut told the PM that his space sojourn was 'not my journey alone but also our country's'. 'We trained for a year and I learnt about different after coming here, everything even small things are different because there is no gravity in by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Livguard Lithium-X: The Future of Power Backup Livguard Shop Now Undo here is a big challenge...I can even sleep on the roof. It takes some time to get used to this environment,' Shukla told the PM, while adding, 'Right now, we are travelling at a speed of 28,000 kmph and I am talking to you with my legs tied. ' 'This speed reflects how fast our nation is progressing and now, we must go even beyond this,' he said. The astronaut said the space station orbits Earth 16 times a day and that he is privileged to witness 16 sunrises and 16 sunsets every day. While referring the astronaut as 'Shux', PM gave him 'homework', telling him to learn as much as possible because the lessons learnt from this Axiom-4 mission 'will have to be extensively used in the Gaganyaan mission , our own Bharatiya Antariksh Station and also for landing an Indian on the Moon.' Shukla told Modi that he is 'absorbing experiences at ISS like a sponge'. When the PM asked about Indian delicacies he carried to space and whether he shared them with his space mates, Shukla said he is carrying 'gajar ka halwa, moong dal halwa, and aamras into orbit'. 'I wanted my fellow crew members from other countries to taste India's heritage. We all sat together and enjoyed it. They loved it,' Shukla said. Shukla shared his reflections from space — on science, struggle, and the boundless dreams of a rising nation. The call was more than ceremonial. It was a glimpse into how India's spacefaring ambitions have matured. Modi described Shukla's journey not as a solitary voyage but as India's own orbit of progress. 'When I was a child, I never imagined I could become an astronaut. But today, modern India enables the realisation of such dreams,' Shukla said. When asked by Modi about microgravity tests he will carry out on ISS, especially from the medicine and agriculture sectors, Shukla said, he 'will do seven experiments'. 'Today, I am going to do a test on stem cells. I am doing a test on supplements to see if such supplements can help prevent muscle loss. This will help people in old age who are losing muscle due to ageing,' he said. Another test explores the cultivation of nutrient-rich microalgae, which could boost food security back home. 'The advantage of space,' he said, 'is that processes happen quickly. That accelerates research and inspires children back home to say, 'I can go there too'.' PM Modi asked what message he would send to India's youth. Shukla responded with clarity and conviction: 'Never stop trying. Whether today or tomorrow, success will come if you don't give up. This is just the first chapter of India's space story. We'll build our own space station. We'll land Indian astronauts on the Moon. And, I'm documenting everything—every lesson I learn will help others fly sooner.' His final words struck a chord destined to echo across classrooms, command centres and quiet corners of the country: 'The sky is never the limit—not for me, not for you, and not for India.' 'Bharat Mata Ki Jai' chant filled up the space station as the PM raised the slogan towards the end of the 18-minute conversation, which was reciprocated by Shukla.