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First of Its Kind in the Region: KFSHRC Successfully Performs Endoscopic Sleeve Gastroplasty on Kidney Transplant Patient

First of Its Kind in the Region: KFSHRC Successfully Performs Endoscopic Sleeve Gastroplasty on Kidney Transplant Patient

RIYADH, Saudi Arabia, June 12, 2025 (GLOBE NEWSWIRE) — In a medical achievement considered the first of its kind in the region, King Faisal Specialist Hospital & Research Centre (KFSHRC) in Riyadh has successfully performed an endoscopic sleeve gastroplasty (ESG) on a patient who had previously undergone a kidney transplant, a case that requires meticulous management of immunosuppressive medications and the prevention of any complications that could jeopardize the transplanted organ. This procedure marks a significant advancement in providing safe treatment solutions for transplant recipients, to improve their graft survival and quality of life.
Known as Endoscopic Sleeve Gastroplasty (ESG), the procedure differs from surgical sleeve gastrectomy in that it requires no abdominal incisions, which is important for transplant patients. Instead, it uses an endoscope inserted through the mouth to suture the stomach internally, effectively reducing its volume and enabling the patient to lose weight and improve overall health.
The procedure aimed to address obesity and metabolic, which are among the leading factors that can negatively impact the health of a transplanted kidney, increase cardiovascular risk, and reduce long-term patient outcomes.
The procedure was performed by a multidisciplinary team of medical experts, led by Dr. Ehab Abufarhaneh, Consultant in Adult Transplant Gastroenterology and Hepatology. The team included gastroenterologists, an upper GI surgeon, transplant surgeons, transplant Nephrology, and transplant anaesthesiologists, all supported by highly trained nursing staff to ensure the highest level of safety, with particular focus on managing the patient's immunosuppressive regimen—critical to preserving kidney graft function.
This achievement underscores the pivotal role of KFSHRC's Organ Transplant Centre of Excellence as a leading medical environment capable of delivering precise interventions for complex transplant cases. By adopting innovative techniques tailored to the unique needs of transplant patients and developing treatment protocols that address post-transplant challenges, the centre reinforces its position as a regional referral hub for cases beyond the scope of conventional treatment pathways.
The success of this procedure further exemplifies KFSHRC's ongoing commitment to delivering advanced, patient-centred healthcare and fulfilling its vision of being the optimal choice for patients supported by an integrated ecosystem of education, research, and clinical excellence that aligns with the ambitions of Saudi Arabia's health sector.
It is noteworthy that KFSHRC has been ranked first in the Middle East and North Africa and 15th globally in the list of the world's top 250 Academic Medical Centres for the third consecutive year and recognised as the most valuable healthcare brand in the Kingdom and the Middle East, according to the 2025 Brand Finance rankings. Additionally, it was included in the World's Best Smart Hospitals list for 2025 by Newsweek magazine. For more information, visit
www.kfshrc.edu.sa
or contact our media team at
mediacoverage@kfshrc.edu.sa
.
A photo accompanying this announcement is available at
https://www.globenewswire.com/NewsRoom/AttachmentNg/e683bcda-0992-4aff-aa47-5664815d432c
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Nature Methods Paper Leverages PacBio Sequencing Technology to Develop the Platinum Pedigree Benchmark, a New Standard for Accurate Characterization of Variation in the Human Genome that Improves Training for AI Models
Nature Methods Paper Leverages PacBio Sequencing Technology to Develop the Platinum Pedigree Benchmark, a New Standard for Accurate Characterization of Variation in the Human Genome that Improves Training for AI Models

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Nature Methods Paper Leverages PacBio Sequencing Technology to Develop the Platinum Pedigree Benchmark, a New Standard for Accurate Characterization of Variation in the Human Genome that Improves Training for AI Models

The most comprehensive, family-based variant dataset ever published will improve variant classification using AI-based tools MENLO PARK, Calif., Aug. 04, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leading provider of high-quality, highly accurate sequencing platforms, today announced the results of a study published in Nature Methods describing a new, comprehensive truth-set of genomic variation which characterizes simple and complex variation. These improved benchmarks were used to retrain Google's DeepVariant, a popular AI-based variant calling tool, resulting in a 34% reduction in erroneously called variants. This resource (the Platinum Pedigree) was built by scientists from PacBio in collaboration with researchers at the University of Washington, the University of Utah, and several other institutions. Combining inheritance-based validation with long-read sequencing, this benchmark accurately characterizes variants, even in difficult, repeat rich regions of the genome, producing the most complete view of validated genetic variation to date. 'Comprehensive benchmarking datasets that include all variant types are foundational to progress in genomics methods development and the application of AI-driven tools, as well as to our understanding of genomic variation for both research and diagnostic purposes,' said Zev Kronenberg, lead author and Senior Manager at PacBio. 'The Platinum Pedigree benchmark doesn't just include simple variants in easy-to-sequence regions, it includes variants from across the entire genome, including regions that were previously excluded from benchmarks due to their complex nature.' The Platinum Pedigree dataset was developed using deep sequencing from three sequencing platforms across a 28-member, multi-generational family (CEPH-1463). By tracking the inheritance of genetic variants from parents to multiple children, the study confidently catalogs over 37 Mb of genetic variation segregating within the family from single nucleotide variants to large structural variants. The dataset introduces the first large pedigree-validated tandem repeat and structural variant truth sets. It also adds more than 200 million bases extending the benchmark regions to 2.77 Gb, including difficult-to-map areas such as segmental duplications and low-complexity regions. A Benchmark Built for the Dark Genome As a demonstration of the value of improved benchmarks to improve AI and ML methods, the researchers retrained Google's DeepVariant - a popular software tool that employs deep learning to identify genetic variants - using the Platinum Pedigree benchmark data. This updated DeepVariant model reduced errors by up to 34% genome-wide, including even higher gains in the most challenging regions of the genome. 'This benchmark pushes accuracy where it matters most,' said Michael Eberle, senior author and Vice President of Computational Biology at PacBio. 'It enables better evaluation of variant calling pipelines and accelerates the development of methods that finally reach the full genome, including some of the complex regions that are important for human health.' A New Standard for Clinical and Population Genomics The Platinum Pedigree benchmark is freely available and already being used by scientists to develop new sequence analysis tools and validate clinical sequencing workflows. It also provides a roadmap for future benchmarking efforts, especially those involving more complete genomes like T2T-CHM13. The full dataset, analysis code, and pipelines are publicly available at: About the Study The study, 'The Platinum Pedigree: A long-read benchmark for genetic variants,' was published in Nature Methods on August 4, 2025. 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Forward Looking Statements This press release contains 'forward-looking statements' within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact are forward-looking statements, including statements relating to the uses, advantages, quality or performance of, or the benefits or expected benefits of using, PacBio products or technologies, including in connection with the Platinum Pedigree dataset, its potential to enable better evaluation of variant calling pipelines and accelerate development methods that reach the full genome, and other future events. You should not place undue reliance on forward-looking statements because they are subject to assumptions, risks, and uncertainties that could cause actual outcomes and results to differ materially from currently anticipated results. These risks include, but are not limited to, rapidly changing technologies and extensive competition in genomic sequencing; unanticipated increases in costs or expenses; and other risks associated with general macroeconomic conditions and geopolitical instability. Additional factors that could materially affect actual results can be found in PacBio's most recent filings with the Securities and Exchange Commission, including PacBio's most recent reports on Forms 8-K, 10-K, and 10-Q, and include those listed under the caption 'Risk Factors.' These forward-looking statements are based on current expectations and speak only as of the date hereof; except as required by law, PacBio disclaims any obligation to revise or update these forward-looking statements to reflect events or circumstances in the future, even if new information becomes available Contacts Investors and Media:Todd Friedmanir@ Media: ir@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Noom Launches Microdose GLP-1 Program, Enabling Weight Loss Without the Side Effects and Priced at $119 to Start, Including Medication and Microhabits Program
Noom Launches Microdose GLP-1 Program, Enabling Weight Loss Without the Side Effects and Priced at $119 to Start, Including Medication and Microhabits Program

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Noom Launches Microdose GLP-1 Program, Enabling Weight Loss Without the Side Effects and Priced at $119 to Start, Including Medication and Microhabits Program

70% of Noom members receiving microdoses of GLP-1 with lifestyle support report no side effects, while experiencing significant weight loss and overall health gains The program addresses all three major barriers to bending the obesity curve in the US: excessive US prices of medication, medication side effects, and sustainable lifestyle change NEW YORK, Aug. 04, 2025 (GLOBE NEWSWIRE) — Noom , the leading digital healthcare company committed to chronic disease prevention and empowering people to live better longer, today announced the launch of the Noom Microdose GLP-1Rx Program, a groundbreaking offering designed to unlock weight loss and long-term health benefits while minimizing side effects through personalized microdoses of GLP-1 medication, when clinically appropriate. The Microdose GLP-1Rx Program is priced at $119 to start, followed by $199 per month, which includes medication, if prescribed, and Noom's powerful GLP-1 Companion, providing clinical care, coaching, and a personalized healthy habits program. The US obesity rate, after decades of unstoppable growth, has at last started to plateau, but at a level that continues to lead the developed world. The US rate of obesity stands at more than 40% versus the UK at 26%, Germany at 23%, and France at 10%. Meanwhile, GLP-1 medications cost as much as 5x more in the US than in these same countries. Three core barriers prevent broader and faster progress: medication cost, medication side effects, and the lack of sustainable behavior change. Noom's Microdose GLP-1Rx Program directly addresses each of these three barriers, to help meaningfully bend the obesity curve. Only affordable GLP-1s and Behavior Change will bend this curve. Noom's physician-designed program employs a 'low and slow' titration approach with microdoses that are a fraction of conventional maintenance doses. Noom's data has shown that members on microdoses are far less likely to have destabilizing side effects. In fact, 70% of Noom members receiving microdoses report no side effects at all. At the same time, members achieve up to 11 pounds of weight loss in 30 days and up to 17 pounds in 60 days at microdose dosages. Meanwhile, studies indicate the vast majority–more than 70%–of patients on standardized protocols experience side effects . 'In the Microdose GLP-1Rx Program, we set out to virtually eliminate side effects for the vast majority, so that more than 70% of people would encounter no side effects. In both my clinical experience and evidence in published studies, it is clear that many people discontinue GLP-1 treatment because of side effects,' said Dr. Jeffrey Egler, Chief Medical Officer at Noom. 'The Noom Microdose GLP-1Rx Program was designed to address this issue by introducing GLP-1s gradually and sustaining them at a microdose level, as part of a larger holistic behavior change platform, which we call our GLP-1 Companion. This approach helps more patients stay on the treatment, experience the full health benefits of these medications, and make real progress in reducing obesity and overweight rates in the United States.' Noom's Microdose GLP-1Rx Program is based on scientific principles: Self-efficacy boosts success with healthy habits . GLP-1 medication makes it easier to adopt healthy habits, while healthy habits improve health outcomes. Members who engage with Noom's GLP-1 Companion achieve 10% weight loss by month 4 at twice the rate compared to those who are not engaged. Noom members on GLP-1s actually log more meals, weigh in more often, and log more exercise by their second month than those on Noom without a GLP-1. . GLP-1 medication makes it easier to adopt healthy habits, while healthy habits improve health outcomes. Members who engage with Noom's GLP-1 Companion achieve 10% weight loss by month 4 at twice the rate compared to those who are not engaged. Noom members on GLP-1s actually log more meals, weigh in more often, and log more exercise by their second month than those on Noom without a GLP-1. Strong weight loss outcomes at lower doses are both achievable and well established in the literature. A 2,700‑person real‑world study presented at the 2025 European Congress on Obesity showed an average 16% weight‑loss over 64 weeks at microdose levels of semaglutide. Meanwhile, another study in The New England Journal of Medicine shows just 33% of the dose of one popular GLP-1 drove 72% of the weight loss at week 72 with a lower side effect profile. A 2,700‑person real‑world study presented at the 2025 European Congress on Obesity showed an average of semaglutide. 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Within that band, the exact dosage schedule is established one member at a time: our physician-prescribed protocol, aided by Noom's SmartDose experience, guides members to the lowest dose that achieves health goals. Factors influencing that decision include BMI, weight loss speed, side effect profile, and other health data. 'Noom has a unique, proprietary dataset that permits the level of deep personalization that our program deploys,' continued Dr. Jeffrey Egler. 'The Noom program has comprehensive data on patient health, injection dates, side effects, and weight-loss speed, and we bring that data to bear to personalize the dosing to maximize outcomes and adherence not just to the medication, but to our Noom microhabits program.' While many eligible GLP-1 users are deterred from starting medication due to fear of incurring side effects, others are challenged by high medication costs. Among those who do start using GLP-1s, over 50% stop due to costs , and as many as 36% stop due to side effects . Noom's Microdose GLP-1Rx Program bridges this gap by offering a more personalized, tolerable path to treatment. It is built on a guiding principle of using the lowest effective dose first. Rather than increasing medication on a fixed schedule, Noom's physician-designed protocol adjusts dosing based on each patient's individual progress and response. This approach enables personalized care that supports meaningful weight loss while minimizing side effects and helping more people adhere to the treatment. GLP-1s and Weight Loss Accessibility – Solving Today's High-Priced Drug Crisis GLP-1 medications continue to be significantly more affordable around the world than in the United States. Popular GLP-1 medications are priced around $99 a month in many developed nations, but at $499 a month to cash-pay patients in the United States. Cost is a major barrier to accessibility in the US, where the price of medications and healthcare services are often much higher than internationally. Noom's accessibly priced Microdose GLP-1Rx Program, starting at $119, builds on the company's advocacy efforts on behalf of patients in the US. In April 2025, Noom sponsored a back cover advertisement in the The Wall Street Journal calling for the creation of a High-Priced Drug List by HHS. The High-Priced Drug List is a market-based solution enabling competition from the country's 503A and 503B pharmacies when medications are priced higher in the United States compared to other developed countries. In addition to the launch of Noom's Microdose GLP-1Rx Program, on Wednesday, July 30th, at an event at The White House, Noom pledged to make available a free tier of Noom to all Americans – regardless of income or BMI. The free tier will launch before the end of the summer and deliver a personalized experience focused on building healthy habits in nutrition, physical activity, and stress reduction. 'Medication alone will not end the obesity epidemic. Lifestyle change is essential,' said Cook. 'By offering a no-cost way for anyone to build healthy habits with Noom, we can reach millions more Americans with the tools to help them live better longer. Pairing that with our new microdose GLP-1 program will help bend the curve on obesity rates in the United States.' Noom Microdose GLP-1Rx Program includes: Microdose GLP-1 medication, if prescribed Full access to the Noom GLP-1 Companion behavior and microhabits program 24/7 access to message doctors and care coordinators Noom premium 1:1 health coaching Prescription home delivery Pricing: $119 to start and then $199 per month Looking Ahead to Longevity 'GLP-1s with Noom's microhabit program represent a modern treatment for the ills of modernity,' said Cook. 'We help people sustain a healthy weight in a food environment engineered for dopamine-hits and excess consumption. By helping people limit compulsive eating and drinking, motivate movement, and reduce chronic inflammation, which we know GLP-1s can do, we promote a higher quality life.' 'The latest science demonstrates that we should be thinking about GLP-1 medication differently,' said Dr. Jeffrey Egler. 'GLP-1s are no longer only useful for weight loss and diabetes – they are critical for building metabolic resilience and reducing inflammation, making them a powerful component of whole-person, lasting health. For our patients, we see GLP-1s as the first step in an extraordinary journey to true vitality.' The Microdose GLP-1Rx Program is available to Americans in 45 states at the following link: About Noom: Noom is the leading whole-person health platform, combining personalized medication with psychology and habit science to help people take control of their metabolic health, weight, and longevity. Noom Health partners with top health plans and employers to offer a suite of solutions, including Noom Med, Noom Weight, Noom GLP-1 Companion, and Noom Diabetes Management and Diabetes Prevention Program to millions. Founded on a mission to empower everyone everywhere to live better longer, Noom has received multiple National Institute of Health grants and was the first mobile app recognized by the CDC as a certified diabetes prevention program. With offices in New York City and Princeton, NJ, Noom has been named one of Inc.'s Best Places to Work, Quartz's Best Workplaces for Remote Workers, and Fortune's Best Workplaces in Technology. Learn more at , subscribe to our blog , or follow us on Twitter and LinkedIn . Contact:Brandyn Bissinger [email protected]

Why Nutraville's Pineal Awakening Formula Is Fueling 2025's 'Wealth Resin' Search Surge
Why Nutraville's Pineal Awakening Formula Is Fueling 2025's 'Wealth Resin' Search Surge

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Why Nutraville's Pineal Awakening Formula Is Fueling 2025's 'Wealth Resin' Search Surge

New York, Aug. 02, 2025 (GLOBE NEWSWIRE) — Introduction High in the remote Himalayas, local monkeys scale near-vertical cliffs to access a strange black substance that oozes from the rocks — a behavior that has baffled scientists and intrigued spiritual communities for centuries. This 'wealth resin,' known traditionally as Shilajit, has become the subject of renewed public interest as modern wellness seekers explore its potential connection to pineal gland health, intuitive clarity, and enhanced dream states. Recent online surges in search phrases like 'pineal decalcification,' 'third eye activation,' and 'Shilajit for manifestation' indicate a cultural shift. Fueled by influencers, ancient texts, and anecdotal discovery, the conversation is accelerating — and Pineal Awakening now sits at the center of that movement. The company behind this formulation presents a modern take on a long-forgotten natural compound, leveraging ingredient transparency, tradition, and bioavailability to address a problem almost no one is talking about: the calcification of the pineal gland. For individuals exploring alternative approaches to mental clarity and self-guided transformation, this isn't just a trend — it's a signal. And it's happening fast. Discover what's inside the Pineal Awakening system by visiting the official site here: Explore the Full Pineal Awakening Formula Why Interest in Pineal-Linked Search Terms Is Surging in 2025 Across search engines, forums, and video platforms, there's been a measurable uptick in interest surrounding phrases like 'decalcify the third eye,' 'pineal gland reset,' and 'how to activate intuition.' Google Trends confirms a sustained rise in global search behavior targeting terms previously confined to fringe spirituality — now entering mainstream wellness. TikTok creators post pineal-related rituals. Reddit threads dissect natural methods of brain 'defogging.' YouTube videos exploring DMT, lucid dreaming, and pineal energy protocols are racking up millions of views. Even wellness podcasts now mention 'spiritual clarity molecules' and 'internal frequency tuning' as part of modern optimization stacks. But what's driving this interest? According to digital research group TrendLens, terms like 'Shilajit pineal gland,' 'resin for third eye,' and 'natural decalcifiers' are experiencing a 300–400% increase year-over-year. This suggests a broader cultural reevaluation of how ancient practices and neurological science intersect. Unlike short-lived supplement fads, this movement appears anchored in persistent consumer questions: Why do I feel disconnected? What's blocking my intuition? Is there a physical reason manifestation techniques don't work for me? The idea that pineal calcification — caused by modern exposures like fluoride, heavy metals, and EMF stress — might be playing a role has transformed from niche theory into a talking point among health-conscious communities. And more people are asking whether natural compounds like Shilajit might offer a tool for self-directed neurological renewal. These questions may not have definitive answers. But the conversation is growing louder — and the resin at the center of it all is gaining serious momentum. Learn more about how Pineal Awakening fits into this movement here: Explore the Science Behind Pineal Awakening Ingredients Pineal Awakening's Ingredient-First Response to These Trends As curiosity around pineal gland optimization intensifies, Pineal Awakening has emerged with a formulation rooted in transparency, tradition, and targeted synergy. Unlike trendy cognitive enhancers that rely on synthetic stimulants, this product is positioned squarely within the 'clean label' movement — prioritizing natural ingredients that align with what many users are already seeking online: clarity, simplicity, and substance. At the core of Pineal Awakening is a rare form of Himalayan Shilajit — a resin that local monks have revered for centuries. Rather than being processed into diluted powders or cut with fillers, the Shilajit used in this blend is sourced through a high-altitude family operation using traditional extraction methods that preserve molecular integrity. It's a dense, black, mineral-rich substance formed over thousands of years by pressure and organic decay — not something fabricated in a lab. But Pineal Awakening isn't just about single-ingredient purity. Its creators recognized that detoxifying the pineal gland is only one part of a deeper process. That's why this formula includes what they call the Pineal Activation Stack — a three-phase support system designed to help cleanse, protect, and stimulate the brain's most overlooked gland. Rather than making bold claims, the brand offers an ingredient-first framework built around consumer goals: mental clarity, intuitive access, and spiritual alignment. Every capsule is backed by the philosophy that ancient bioactive compounds — when purified and combined with modern insight — can serve a supportive role in the pursuit of higher cognitive performance. For those interested in this blend of science and ancestral wisdom, a closer look at Pineal Awakening may reveal more than just another supplement. Get the full breakdown of what's inside: Discover What's Inside the Pineal Awakening Formula Ingredient Spotlight – What's Inside the 'Wealth Resin' Formula At the heart of Pineal Awakening is Shilajit — the so-called 'wealth resin' revered by ancient Himalayan cultures, mentioned in explorer journals, and now attracting attention in neuroscience-adjacent wellness circles. Unlike mass-market powders or diluted extracts, this formula utilizes ultra-pure Shilajit resin harvested using generational techniques designed to preserve both its mineral content and molecular integrity. But Shilajit is only the beginning. Pineal Awakening's creators identified several synergistic compounds that support the resin's natural mechanisms, enhancing its potential to assist with pineal detoxification, oxidative stress, and neurological clarity. Below are a few of the formula's most discussed components, presented in an informational, non-clinical context: Shilajit – Known in traditional medicine and modern biohacking communities for its fulvic acid content, this resin is valued for its ability to cross the blood-brain barrier. In public wellness discussions, it's frequently associated with focus, clarity, and inner stillness. – Known in traditional medicine and modern biohacking communities for its fulvic acid content, this resin is valued for its ability to cross the blood-brain barrier. In public wellness discussions, it's frequently associated with focus, clarity, and inner stillness. Chlorella – A freshwater algae often referenced in environmental detox literature. While not clinically proven for pineal use, it is a popular subject in discussions about heavy metal chelation and cellular oxygenation. – A freshwater algae often referenced in environmental detox literature. While not clinically proven for pineal use, it is a popular subject in discussions about heavy metal chelation and cellular oxygenation. Burdock Root – Traditionally used to support liver and lymphatic system function, this plant appears frequently in botanical wellness protocols that aim to assist internal purification. – Traditionally used to support liver and lymphatic system function, this plant appears frequently in botanical wellness protocols that aim to assist internal purification. Amla – Called 'Indian gooseberry,' this antioxidant-rich fruit shows up in skin, hair, and vitality regimens. In the context of Pineal Awakening, it serves as part of the protection phase within the 3-part stack. – Called 'Indian gooseberry,' this antioxidant-rich fruit shows up in skin, hair, and vitality regimens. In the context of Pineal Awakening, it serves as part of the protection phase within the 3-part stack. Turmeric – Widely known for its role in inflammation response. Curcumin, its active compound, is often mentioned in brain longevity and clarity-related content. – Widely known for its role in inflammation response. Curcumin, its active compound, is often mentioned in brain longevity and clarity-related content. Schisandra – A cornerstone of Traditional Chinese Medicine, this adaptogen is increasingly discussed in connection with neurotransmitter activity and stress modulation. Some describe it as helping to 'turn up the volume' on inner awareness. Together, these elements form the Pineal Activation Stack — a proprietary combination that goes beyond detoxification, aiming to create the internal conditions where clarity, creativity, and intuition might begin to resurface. For a deeper look at how each ingredient is sourced and integrated, visit: Explore the Science Behind Pineal Awakening What Reddit, Podcasts & TikTok Creators Are Saying In 2025, online communities are buzzing about the pineal gland — not just in spiritual forums, but across mainstream platforms like Reddit, TikTok, and Spotify-hosted wellness podcasts. The phrase 'third eye decalcification' has gone from niche terminology to a trending search query, prompting new waves of public curiosity. Reddit users have created threads dissecting daily protocols for pineal clarity, with many citing Shilajit as a recurring theme. Posts with thousands of upvotes explore non-medical regimens, including cold exposure, breathwork, and fulvic acid intake — often speculating on their role in restoring intuition or improving lucid dreaming. Meanwhile, TikTok creators produce short-form content with millions of views, walking audiences through pineal 'cleansing routines' and morning rituals involving resin-based formulas. These clips, typically framed around self-awareness and inner vision, reflect a generational shift toward decentralized wellness — one rooted in exploration rather than prescription. Podcast discussions have also surged. Interviews with neuro-enthusiasts and holistic researchers often touch on electromagnetic exposure, fluoride accumulation, and lifestyle stressors that may affect the pineal region. While guests are careful not to make medical statements, they frequently reference the gland's symbolic and neurological roles, citing its central position in spiritual traditions across cultures. This public conversation doesn't prove or disprove anything — but it does illustrate a cultural appetite for tools, language, and formulations that support personal sovereignty and internal exploration. In that context, Pineal Awakening's clean-label design and resonance with ancestral preparation methods are making it a recurring name in pineal-focused content circles. To understand what's driving this groundswell of interest, or to view the formula in question, visit: Learn More About Pineal Awakening and Its Activation Stack Who Might Be Drawn to This Type of Supplementation in 2025 As mainstream interest in mental clarity, intuitive awareness, and digital detox deepens, a growing demographic is seeking out wellness tools that prioritize ancient sourcing and ingredient transparency over temporary stimulation. For these individuals, the goal isn't just more energy — it's alignment. Pineal Awakening appears to resonate with those who feel modern life has dulled their inner compass. These are people who suspect that their mental fog, creative stagnation, or lack of inspiration may have physical roots — and that addressing those roots might open the door to new states of insight. Some are long-time meditation practitioners exploring ways to enhance their depth of focus or dream recall. Others are newcomers to biohacking and self-directed wellness, curious about how compounds like Shilajit, Chlorella, and Schisandra might support a broader mental reset. A significant portion are also professionals — educators, creatives, wellness entrepreneurs — looking for natural ways to restore their cognitive sharpness without relying on synthetic nootropics. What connects these groups is not a shared lifestyle, but a shared feeling: that there's more to access — mentally, emotionally, even spiritually — and that something in their current environment may be blocking it. By combining high-elevation Shilajit with antioxidant-rich support compounds in a phased delivery system, Pineal Awakening has positioned itself as a non-synthetic option for individuals seeking to engage with this deeper layer of optimization. To explore whether this type of ingredient-first formula aligns with your goals, visit: Learn More About the Pineal Awakening System Spiritual Optimization & Pineal Curiosity – 2025 Market Reflections The intersection of neuroscience, spirituality, and self-optimization has become one of the most dynamic frontiers in the wellness sector. In 2025, consumer demand is shifting beyond physical performance enhancers and toward supplements that support what many describe as 'energetic alignment,' 'internal clarity,' or 'cognitive sovereignty.' This evolution isn't driven by hype, but by behavior. People aren't just buying supplements — they're searching, listening, reading, and testing protocols for themselves. And in that testing, a quiet pattern is emerging: formulas with ancient roots and modern scientific curiosity are generating sustained interest. The pineal gland has become a focal point for this shift. Whether viewed through the lens of sleep regulation, intuitive awareness, or symbolic resonance, it represents something primal. And products that acknowledge both the biological and metaphysical conversation — without making unsupported claims — are gaining traction among mindful consumers. Within this movement, Pineal Awakening stands as an example of what some call the 'third wave' of supplementation: formulas that balance clean sourcing, holistic structure, and functional framing without falling into either mysticism or clinical overreach. It's not about promising transformation — it's about offering tools for people on that path already. To see how Pineal Awakening reflects these market dynamics, and to explore the formula behind the movement, visit: Explore the Full Pineal Awakening Formula The Public Debate Around the Wealth Resin – Signals, Skepticism, and Saturation As with any substance gaining cultural traction, the rise of Shilajit — especially in the context of pineal gland conversation — has sparked a range of responses. From cautious optimism to vocal skepticism, the dialogue reflects a public still navigating the space between tradition and science. Supporters describe the resin as a mineral-rich compound aligned with holistic vitality. They point to its long-standing use in Ayurvedic systems, its inclusion in historical military campaigns, and its widespread reference in spiritual disciplines. For many, it symbolizes a return to elemental simplicity — something nature created, untouched by mass manufacturing or synthetic design. Others express skepticism. They question whether anecdotal benefits can be reliably linked to the resin itself, or whether placebo, context, and expectation play a larger role. Forums often debate whether modern Shilajit sourcing matches the purity referenced in ancient texts, or whether the current surge is part of a broader marketing wave. Then there are neutral observers — individuals not sold on the mystical framing, yet intrigued by the fulvic acid research, mineral density profiles, and potential neurological implications. For them, the 'wealth resin' is less about belief and more about experimentation: an ingredient worth testing, not worshipping. Pineal Awakening doesn't claim to settle this debate. Instead, it offers a formulation for those curious enough to explore — and committed enough to do so through clean, transparent supplementation. To learn more about the formula at the center of this conversation, visit: View Details About Pineal Awakening's Full Ingredient Stack About Nutraville Nutraville is a holistic wellness company dedicated to bridging ancient spiritual wisdom with modern nutritional science. Founded on the belief that the pineal gland is the gateway to higher consciousness, Nutraville develops clean-label supplements that support spiritual clarity, intuitive alignment, and optimal cognitive health. Through flagship formulations like Pineal Awakening, PinealXT, and Pineal Guardian, Nutraville integrates time-honored botanical practices with cutting-edge research to help individuals detoxify and activate the pineal gland. Every product is made from 100% vegan, cruelty-free ingredients and is designed to support clarity, focus, and self-guided awakening. Nutraville's mission is to empower individuals to become the best version of themselves — effortlessly and naturally. The company adheres to five core values: Integrity, Holistic Wellness, Innovation, Empowerment, and Community. Whether through supplements, cookbooks, meditation tools, or educational guides, Nutraville exists to help people reconnect with their inner potential and elevate their wellness journey. Contact Disclaimer (FTC + FDA + Affiliate Compliance) This press release is for informational purposes only. The information contained herein does not constitute medical advice, diagnosis, or treatment and has not been evaluated by the Food and Drug Administration (FDA). Pineal Awakening is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician or qualified healthcare provider before beginning any new supplement, routine, or health program. Some links in this release may be promotional in nature and may lead to third-party websites. The publisher or author may receive compensation through affiliate commissions if a purchase is made through these links. This compensation does not affect the price you pay and helps support continued research and content publication. Results described or implied may not be typical and should not be interpreted as guarantees. Statements made about ingredients or outcomes reflect public discussion and historical usage only, and are not endorsed by medical professionals or regulatory agencies. Always do your own research and make informed decisions. Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same. Ahmedabad Plane Crash

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