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No Safety Advantage to Emergency Robotic Cholecystectomy

No Safety Advantage to Emergency Robotic Cholecystectomy

Medscape04-06-2025
TOPLINE:
In acute care settings, robotic-assisted cholecystectomy (RAC) and laparoscopic cholecystectomy (LC) resulted in similar rates of bile duct injury, but RAC was associated with higher rates of major postoperative complications, more frequent drain placement, and longer hospital stays than LC.
METHODOLOGY:
Although some prior studies have raised concerns about increased bile duct injury with RAC vs LC, their relative safety in acute care surgery remains unclear.
Researchers conducted a retrospective cohort analysis using commercial claims and encounter data from 2016 to 2021 to compare outcomes between RAC and LC in acute care surgery.
The primary outcome was bile duct injury; secondary outcomes included major postoperative complications, the use of a postoperative drain, length of hospital stay, surgical site infections, and conversion to open surgery.
TAKEAWAY:
Researchers included 844,428 adults (mean age, 45.6 years; 64.9% women), with 35,037 undergoing RAC and being propensity-matched with an equal number of adults who underwent LC.
Adoption of RAC increased from 2.2% in 2016 to 8.2% in 2021.
Bile duct injury rates were similar between the groups (P = .54).
RAC vs LC was associated with higher rates of major postoperative complications (8.37% vs 5.50%; P < .001), an increased use of postoperative drains (0.63% vs 0.48%; P < .001), and a longer median hospital stay (3 vs 2 days; P < .001).
Use of intraoperative cholangiograms was more common in the LC than in the RAC group (P < .001), whereas RAC was associated with fewer surgical site infections than LC (0.04% vs 0.09%; P = .02).
Conversion to open surgery was uncommon in both the groups.
IN PRACTICE:
'Although these results may partly reflect case complexity and selection bias, they do not suggest a clear advantage of RAC over the standard, established laparoscopic cholecystectomy,' the authors wrote.
SOURCE:
The study was led by Nathnael Abera Woldehana, MD, MPH, Division of Minimally Invasive Surgery, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore. It was published online in JAMA Surgery.
LIMITATIONS:
The retrospective design may have introduced selection bias and unmeasured confounding factors. The study's generalizability is limited to commercially insured populations. Long-term outcomes such as readmissions, quality of life, and cost-effectiveness were not assessed.
DISCLOSURES:
Some authors reported receiving conference travel/attendance support, consulting fees, grants, advisory board fees, and speaker fees and having other ties with several organizations and pharmaceutical companies.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
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City of Hope's Dr. Yuman Fong Delivers Lister Legacy Lecture, Spotlighting Surgical Cancer Innovations
City of Hope's Dr. Yuman Fong Delivers Lister Legacy Lecture, Spotlighting Surgical Cancer Innovations

Business Wire

time25-06-2025

  • Business Wire

City of Hope's Dr. Yuman Fong Delivers Lister Legacy Lecture, Spotlighting Surgical Cancer Innovations

LOS ANGELES--(BUSINESS WIRE)-- Yuman Fong, M.D., chair of the Department of Surgery at City of Hope ®, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center named a Top 5 'Best Hospital' in the nation for cancer care by U.S. News & World Report, this month delivered the Lister Legacy Lecture at the triennial conference of The Royal College of Surgeons of Edinburgh. This presentation honors the long-term impact of Baron Joseph Lister, M.D., who brought antiseptic techniques and many other innovations to surgery, saving more lives and making a real difference in how patients live. 'I am humbled to have been asked to speak on 'The Surgeon in the 21st Century.' Sir Joseph Lister's work with antiseptics laid the foundation for the sterile surgical practices we rely on today. His forward-looking mindset has inspired me to collaborate with doctors and med-tech companies around the world to push the boundaries of surgical innovation. 'At City of Hope, we are exploring the use of AI and robotics in research settings to make it one day possible for specialists to perform remote surgery together. The goal is to make exceptional cancer surgery available to everyone — no matter where they live or how close they are to a major cancer center,' said Dr. Fong, City of Hope's Sangiacomo Family Chair in Surgical Oncology. The Royal College of Surgeons of Edinburgh is one of the oldest surgical colleges in the world and is where the father of modern surgery, Dr. Joseph Lister, worked for much of his career as a general surgeon, pathologist and medical scientist. Before Dr. Lister's pioneering work in antiseptics, people were just about ready to give up on surgery altogether because infections were killing so many patients. Dr. Lister is still on people's lips today; the popular mouthwash Listerine was named in honor of him. Dr. Fong Is Curing Stage 4 Colorectal Cancer Metastatic colorectal cancer that has spread to the liver was once considered incurable. Dr. Fong is known internationally for his expertise in liver surgery and for proving that liver resection sometimes can cure Stage 4 colorectal cancer. In fact, he devised a new scoring system called the Fong Score that is widely used in staging for this population of patients, allowing surgeons to plan a path toward surgical cure. Along the journey to less invasive liver therapies, Dr. Fong has contributed to the design and deployment of many new minimally invasive surgical and interventional tools that are used worldwide. More recently, Dr. Fong led a team that demonstrated robotic liver surgery can safely and routinely be performed as outpatient surgery. The Next Generation of Gene Therapy Dr. Fong has focused on gene therapy for over two decades, engineering viruses and immune cells to kill cancer. His City of Hope team developed CF33, a cancer-fighting virus that has been shown to shrink colon, lung, breast, ovarian and pancreatic cancer tumors in preclinical laboratory and animal models. Importantly, CF33 wakes up the immune system to join the fight. There are many ongoing multisite clinical trials to evaluate the safety and efficacy of investigational solid and blood cancer therapies based on Dr. Fong's CF33 technology*. Leveraging AI and Wearables to Improve Patient Outcomes Immunotherapies are making more cancers that were previously inoperable operatable. Minimally invasive robotic surgery has turned surgeons into superheroes with computer-aided vision sometimes powered by augmented reality (AR) for a clearer, more interactive view of what's happening inside the body. AR is enabling remote surgery and multispecialty collaboration where surgeons in different locations can work together in real time guided by shared visualizations and data overlays. Remote surgery is still undergoing preclinical testing, though it promises to be a powerful tool in emergency settings when access to top specialists is limited. AI-guided robotic systems are being tested as assistants in complex cancer surgery that can one day decrease the risk of surgical complications. For example, AI could predict how tissue will move and designate 'no go zones' where snips should not occur. In the future, some simple surgical tasks can be automated under the supervision of experienced surgeons, increasing patient safety as well as improving working conditions for surgeons who often have long operating room schedules. Additionally, Dr. Fong and his team are testing how wearables or remote monitoring devices can be leveraged before and after surgery to improve patient outcomes. 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Air Force: Starship to cause few environmental impacts at Cape Canaveral Space Force Station
Air Force: Starship to cause few environmental impacts at Cape Canaveral Space Force Station

Yahoo

time12-06-2025

  • Yahoo

Air Force: Starship to cause few environmental impacts at Cape Canaveral Space Force Station

Would launching up to 76 massive SpaceX Starship rockets atop Super Heavy boosters per year — accompanied by up to 152 sonic-boom-producing landings — generate few significant environmental impacts from Cape Canaveral Space Force Station's Launch Complex 37? That's what a newly released Air Force draft environmental impact statement determined. However, Charlie Venuto, past president of the Merritt Island Wildlife Association, worries how Starship's thunderous noise and vibrations will affect ecologically threatened Southeastern beach mice and nesting sea turtles — along with air and water quality — across the nonprofit's namesake 140,000-acre national wildlife refuge and Canaveral National Seashore. The draft EIS acknowledged that Starship-Super Heavy launches and sonic booms from Launch Complex 37 would constitute a "community annoyance" for areas like Cape Canaveral, Titusville and Cocoa Beach. And in a move cheered by MIWA officials, the study eliminated from further analysis the thought of building new Starship launch complexes at two greenspace areas at the Cape, citing high potential of endangered species and archaeological sites. Cape Canaveral: Is there a launch today? Upcoming SpaceX, Axiom, ULA rocket launch schedule at Cape Canaveral "The refuge has more endangered and threatened species than any other refuge in the continental U.S. So you know, we have an obligation. I know, working on shuttle, that was always a major concern," Venuto said. He was manager of environmental safety for USBI, NASA's prime contractor for shuttle solid rocket boosters. "We wanted to maintain that balance between technology and nature. And it seemed like we did a pretty good job of that," Venuto said. SpaceX seeks regulatory permissions to start launching Starship rockets from Launch Complex 37 at the Space Force installation and pad 39A at NASA's neighboring Kennedy Space Center. The enormous economic undertaking will generate at least $1.8 billion of capital investment and generated about 600 new full-time jobs by 2030, Gov. Ron Desantis' office announced. The Air Force's 176-page draft environmental impact statement analyzed potential environmental, social, economic, historic and cultural ramifications from redeveloping about 230 acres of Launch Complex 37 to support Starship-Super Heavy operations starting next year, including launches and booster landings. United Launch Alliance previously used LC-37 to send up hulking triple-core Delta IV Heavy rockets. The last Delta IV Heavy launched in April 2024. Starship infrastructure includes two concrete launch pads, launch mounts, twin 600-foot integration towers, twin 225-foot-diameter landing pads, and landing catch towers. 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To mitigate noise, SpaceX would: Employ sound suppression systems, such as water deluge and flame diverters. Work with Space Launch Delta 45 to notify the community of noise and sonic boom events. Structural damage claims would be investigated, with claimants compensated according to FAA regulations, the Commercial Space Launch Act and Air Force policy. On that topic, the Cape Canaveral City Council is partnering with the Florida Institute of Technology on an upcoming $10,019 rocket launch impact study. Researchers will install sensor suites this summer at buildings across the beachside city to collect data on decibel levels, vibrations and air quality before, during and after all launches from the Cape. Starship-Super Heavy's noise, vibrations and sonic booms will likely adversely affect Southeastern beach mice and Florida scrub-jays, per the draft EIS. 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Journalism like this takes time and resources. Please support it with a subscription here. This article originally appeared on Florida Today: Merritt Island refuge backers concerned about Starship wildlife impacts

Video Game Improves Trauma Triage in EDs
Video Game Improves Trauma Triage in EDs

Medscape

time12-06-2025

  • Medscape

Video Game Improves Trauma Triage in EDs

In a secondary analysis of a trial, exposure to an educational video game on trauma triage was associated with a moderate increase in emergency department (ED) physicians' willingness to transfer injured patients to trauma centers and a smaller improvement in their ability to recognize severely injured patients. METHODOLOGY: Researchers conducted a process evaluation of a randomized clinical trial that involved 800 physicians (mean age, 43.7 years) responsible for trauma triage at EDs in levels III-V trauma centers and nontrauma centers across the US. Participants were randomly assigned to receive either usual education (control group) or a customized video game intervention designed to recalibrate trauma triage heuristics. Those in the intervention group played the game for 2 hours, after which all participants completed a 36-case virtual simulation to assess decision-making. Researchers used the signal detection theory and analyzed: Perceptual sensitivity, defined as the ability to distinguish between patients who meet vs do not meet criteria for transfer; and decisional threshold, defined as tolerance for false-positive or false-negative decisions. TAKEAWAY: Exposure to the video game was associated with a significant reduction in undertriage rates (22% vs 38%; P < .001) and a slight increase in overtriage (39% vs 34%; P < .001). < .001) and a slight increase in overtriage (39% vs 34%; < .001). Video game intervention led to a moderate increase in tolerance for false-positive decisions (intervention standard deviation [SD] units, 0.14; control SD units, 0.53) and a moderate (Cohen d = 0.60) increase in willingness to transfer. The intervention group was also associated with a higher perceptual sensitivity (1.00 SD units vs 0.87 SD units; P < .001), indicating a small improvement (Cohen d = 0.20) in recognizing severely injured patients. < .001), indicating a small improvement (Cohen d = 0.20) in recognizing severely injured patients. The intervention's effect was more pronounced among physicians working ≥ 10 shifts per month, who showed a greater reduction in undertriage (40% in the control group vs 22% in the intervention group; P = .05). IN PRACTICE: 'The results of this secondary analysis of a randomized clinical trial suggest that educational adventure video games have the potential to improve physician performance in time-sensitive conditions and appear to act by increasing physicians' willingness to implement clinical practice guidelines,' the study authors wrote. SOURCE: This study was led by Deepika Mohan, MD, MPH, Department of Surgery, University of Pittsburgh School of Medicine in Pittsburgh. It was published online on June 4 in JAMA Network Open . LIMITATIONS: The use of simulation for process evaluation may not fully reflect real-world decision-making. Physicians exposed to the intervention may have had an advantage in completing the virtual simulation. Additionally, the differences in response rates between intervention and control groups, potentially due to perceived differences in honoraria value, could have introduced bias. DISCLOSURES: This study was supported by grants from the National Institutes of Health. Two authors reported receiving grants from various sources. One author reported receiving $250 to participate in a stakeholder meeting.

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