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Harper Now Features Vector Indexing for AI-Powered Search

Harper Now Features Vector Indexing for AI-Powered Search

Malaysian Reserve17 hours ago

Release 4.6 Supports Vector-Based Data for Semantic Caching and Semantic Search – EnablingUsers to Better Understand Intent, Deliver Relevant Results, and Drive Conversion Rates
DENVER, June 30, 2025 /PRNewswire/ — Harper, bringing next-level web performance to a digital-first world, today announced the release of version 4.6 of its composable application platform. The latest release features several enterprise-grade components to improve performance and maximize revenue at any scale, chief among them the addition of vector indexing for the efficient storing and retrieving of high-dimensional vector data – essential for bringing contextual depth to AI models like smart search.
For large digital brands with extensive product catalogues, the introduction to AI-enhanced search helps accelerate the customer's journey and time-to-purchase. A new study on shopper expectations found 62% of respondents are more likely to buy when guided by AI-powered recommendations. Among millennials, that number jumps to 68%. Conversely, bad search experiences drive shoppers away, with 72% of consumers abandoning sites due to poor search.
Harper's low-latency architecture and superior performance capabilities are attractive features for large digital brands with high-volume websites. The composable application platform integrates a high-performance database, application server, caching and messaging functions into a single runtime instance, eliminating the need for separate technologies. By keeping data at the edge, Harper lets applications avoid the transit time of contacting a centralized database. Layers of resource-consuming logic, serialization, and network processes between each technology in the stack are removed, resulting in extremely low response times that translate into greater customer engagement, user satisfaction, and revenue growth.
The vector indexing feature found in Harper v. 4.6 powered by the Hierarchical Navigable Small World (HNSW) algorithm, allows for quick and accurate nearest-neighbor search, which is essential in applications like recommendation systems, personalized content feeds, chatbot retrieval, image recognition, and natural language processing. The addition of vector indexing to the Harper platform eliminates the need for third-party vector databases – semantic caching can be done natively in Harper, helping bring down the overall costs of running AI models.
'There's no question, AI is transforming the search box into an intent box,' said Stephen Goldberg, CEO and Cofounder of Harper. 'Enabling semantic cache allows companies to do more than just deliver results – they can respond quickly with the right recommendations, products, and advice to improve customer satisfaction and drive conversion rates. Harper helps accelerate everything in your web experience, from contextual decision-making of AI to the consumer's purchase journey overall.'
Harper is used by data architects and data teams at several Fortune 100 e-commerce companies and destination websites to yield massive savings for massive workloads. Other notable features found in the latest release of the performance platform include:
New plugins API with support for dynamic loading
HTTP logging for improved formatting, control and debugging
New data loader for pre-loading content
Resource API updates
To learn more about these new features visit the Harper v. 4.6 release notes here.
About HarperHarper enables companies to achieve web speed, scale, and performance levels never seen before – with customers reporting as much as 7x faster page loads, nearly 30x faster LCPs, and more than 25 percent year-over-year revenue growth. Its innovative, backend technology collapses the traditional software stack into one highly-efficient, low-latency system with limitless horizontal scale. By combining data, application, cache, and messaging functions into a single process, on a single server, Harper eliminates the constraints and complexity of building, distributing, and maintaining data-dependent applications. In doing so, Harper unlocks new revenue streams for its clients and inspires dev teams to innovate without compromise. To learn more, visit www.harpersystems.dev
Media Contact:April BurghardtPR & Communicationsapril@harperdb.io646-246-0484

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Otago University Migrates from Blackboard to D2L Brightspace
Otago University Migrates from Blackboard to D2L Brightspace

Malaysian Reserve

time7 hours ago

  • Malaysian Reserve

Otago University Migrates from Blackboard to D2L Brightspace

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Ecovyst Issues 2024 Sustainability Report
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Ecovyst Issues 2024 Sustainability Report

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GPCR-Targeting Therapies Market Poised for Strong Growth During the Forecast Period (2025-2034) Across 7MM Due to the Rising Cancer Diagnoses and Drug Pipeline Expansion
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GPCR-Targeting Therapies Market Poised for Strong Growth During the Forecast Period (2025-2034) Across 7MM Due to the Rising Cancer Diagnoses and Drug Pipeline Expansion

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The report also provides insights into the emerging GPCR-targeting therapies, market share of individual therapies, and current and forecasted GPCR-targeting therapies market size from 2020 to 2034, segmented into 7MM. Key Takeaways from the GPCR-Targeting Therapies Market Report As per DelveInsight's analysis, the total market size of GPCR-targeting therapies in the 7MM is expected to surge significantly by 2034. The United States is expected to hold the largest share of the total GPCR inhibitors market among the 7MM. The report provides the total potential number of patients in the indications, such as PTCL, CTCL, Migraine, NASH, and others. Leading GPCR-targeting therapies companies, such as CytoDyn, REMD Biotherapeutics, GPCR Therapeutics, Structure Therapeutics, and others, are developing novel GPCR-targeting therapies that can be available in the GPCR-targeting therapies market in the coming years. 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In June 2020, the drug became commercially available in Germany for adults with Mycosis Fungoides or Sézary Syndrome who had undergone at least one prior systemic treatment. Erenumab, co-developed by Amgen and Novartis, is a fully human monoclonal antibody that selectively binds to and blocks CGRP receptors. CGRP ligands, which are small neuropeptides, contribute to migraine and chronic pain through strong vasodilatory effects. By directly competing with CGRP, erenumab provides a high degree of specificity and effectiveness compared to small-molecule therapies. It is used to treat conditions such as migraine, vasoconstriction, hot flashes, and stable angina pectoris. The antibody received approval in the U.S. in May 2018 and in the EU in July 2018. Learn more about the FDA-approved GPCR-targeting therapies @ GPCR-Targeting Therapies Drugs Key Emerging GPCR-Targeting Therapies and Companies Several key players, including CytoDyn (Leronlimab), REMD Biotherapeutics (Volagidemab), Structure Therapeutics (GSBR-1290), GPCR Therapeutics (GPC-100), and others, are involved in developing drugs for GPCR-targeting therapies for various indications such as NASH, Multiple Myeloma, Diabetes, and others. Volagidemab (REMD-477) is a human monoclonal antibody targeting the glucagon receptor (GCGR), developed by REMD Biotherapeutics for the treatment of juvenile type I diabetes (T1D) and type II diabetes (T2D). It functions by binding to GCGR and competitively inhibiting its signaling pathway. This action enhances glucose uptake by the liver, reduces the breakdown of glycogen and gluconeogenesis, and stimulates glycogen synthesis—collectively contributing to its blood sugar-lowering effects (CK060182). As of March 2021, the drug was being investigated in multiple indications: T1D and T2D were in Phase II clinical trials, glucose intolerance was in Phase I, and metabolic disorders were in the preclinical stage (CK060183). Leronlimab is classified as a viral entry inhibitor, a type of HIV therapy that blocks the virus from penetrating and infecting healthy cells. In contrast to Highly Active Antiretroviral Therapy (HAART), which targets HIV after cell entry and replication, Leronlimab intervenes earlier in the viral life cycle. The critical role of the CCR5 receptor in HIV infection is highlighted by the natural immunity observed in individuals with a genetic mutation that disables CCR5 expression. Leronlimab is currently under development for the treatment of Nonalcoholic Steatohepatitis (NASH), HIV-associated NASH, and various solid tumors, with development efforts currently in Phase II. In April 2019, the company signed multiple agreements with Samsung for the transfer of technology, process validation, manufacturing, and pre-approval inspection services, aimed at supporting the commercial production of Leronlimab's bulk drug substance. The anticipated launch of these emerging therapies are poised to transform the GPCR-targeting therapies market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the GPCR-targeting therapies market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth. To know more about GPCR-targeting therapies clinical trials, visit @ GPCR-Targeting Therapies Treatment Drugs GPCR-Targeting Therapies Overview G protein-coupled receptors (GPCRs) are a vital group of cell surface receptors that regulate numerous physiological processes. In many cancers, GPCR pathways are often dysregulated due to abnormal expression, increased activity, or mutations, contributing to uncontrolled cell growth, blood vessel formation, and metastasis. GPCRs are categorized into several classes based on their structure and function. In humans, the primary classes include Class A (Rhodopsin-like), Class B (Secretin and Adhesion), Class C (Metabotropic glutamate/pheromone), and Class F (Frizzled/TAS2). Additional classes, such as Class D (fungal mating pheromone receptors) and Class E (cyclic AMP receptors), are present in non-human organisms. Among these, Class A is the most extensive, encompassing a majority of hormone, neurotransmitter, and sensory receptors. Class B is split into secretin and adhesion subgroups, Class C comprises receptors for glutamate and GABA, and Class F includes receptors like frizzled and smoothened involved in Wnt signaling. This classification underscores the structural and functional diversity of GPCRs and their critical roles in both normal physiology and disease. GPCR-Targeting Therapies Epidemiology Segmentation The GPCR-targeting therapies market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM, segmented into: Total Cases in Selected Indications for GPCR-Targeting Therapies Total Eligible Patient Pool in Selected Indications for GPCR-Targeting Therapies Total Treated Cases in Selected Indications for GPCR-Targeting Therapies GPCR-Targeting Therapies Report Metrics Details Study Period 2020–2034 GPCR-Targeting Therapies Report Coverage 7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan] Key Indications Covered in the Report PTCL, CTCL, Migraine, NASH, and others Key GPCR-Targeting Therapies Companies CytoDyn, REMD Biotherapeutics, GPCR Therapeutics, Structure Therapeutics, Pfizer, Kyowa Hakko Kirin, Novartis, Amgen, Lundbeck, and others Key GPCR-Targeting Therapies Leronlimab, Volagidemab, GPC-100, GSBR-1290, ZAVZPRET, POTELIGEO, AIMOVIG, VYEPTI, and others Scope of the GPCR-Targeting Therapies Market Report GPCR-Targeting Therapies Therapeutic Assessment: GPCR-Targeting Therapies current marketed and emerging therapies GPCR-Targeting Therapies Market Dynamics: Conjoint Analysis of Emerging GPCR-Targeting Therapies Drugs Competitive Intelligence Analysis: SWOT analysis and Market entry strategies Unmet Needs, KOL's views, Analyst's views, GPCR-Targeting Therapies Market Access and Reimbursement Discover more about GPCR-targeting therapies in development @ GPCR-Targeting Therapies Clinical Trials Table of Contents 1. Key Insights 2. Report Introduction 3. Executive Summary 4. Key Events 5. Epidemiology and Market Forecast Methodology 6. GPCR-Targeting Therapies Market Overview at a Glance in the 7MM 6.1. Market Share (%) Distribution by Indications in 2020 6.2. Market Share (%) Distribution by Indications in 2034 7. GPCR-Targeting Therapies: Background and Overview 7.1. Introduction 7.2. Potential of GPCR-Targeting Therapies in Different Indications 7.3. Clinical Applications of GPCR-Targeting Therapies 8. Treatment and Management 9. Target Patient Pool of GPCR-Targeting Therapies 9.1. Assumptions and Rationale 9.2. Key Findings 9.3. Total Cases of Selected Indication for GPCR-Targeting Therapies in the 7MM 9.4. Total Eligible Patient Pool of Selected Indication for GPCR-Targeting Therapies in the 7MM 9.5. Total Treatable Cases in Selected Indication for GPCR-Targeting Therapies in the 7MM 10. Marketed Therapies 10.1. Key Competitors 10.2. OTELIGEO (mogamulizumab-kpkc): Kyowa Hakko Kirin 10.2.1. Product Description 10.2.2. Regulatory milestones 10.2.3. Other developmental activities 10.2.4. Clinical development 10.2.5. Safety and efficacy 10.3. AIMOVIG (erenumab-aooe): Novartis/Amgen 10.3.1. Product Description 10.3.2. Regulatory milestones 10.3.3. Other developmental activities 10.3.4. Clinical development 10.3.5. Safety and efficacy List to be continued in the report 11. Emerging Therapies 11.1. Key Competitors 11.2. Volagidemab: REMD Biotherapeutics 11.2.1. Product Description 11.2.2. Other developmental activities 11.2.3. Clinical development 11.2.4. Safety and efficacy 11.3. Leronlimab: CytoDyn 11.3.1. Product Description 11.3.2. Other developmental activities 11.3.3. Clinical development 11.3.4. Safety and efficacy 12. GPCR-Targeting Therapies: Seven Major Market Analysis 12.1. Key Findings 12.2. Market Outlook 12.3. Conjoint Analysis 12.4. Key Market Forecast Assumptions 12.4.1. Cost Assumptions and Rebates 12.4.2. Pricing Trends 12.4.3. Analogue Assessment 12.4.4. Launch Year and Therapy Uptakes 12.5. Total Market Sizes of GPCR-Targeting Therapies by Indications in the 7MM 12.6. The United States Market Size 12.6.1. Market Size by Indication in the United States 12.6.2. Market Size by Therapies in the United States 12.7. EU4 and the UK 12.7.1. Market Size by Indications in EU4 and the UK 12.7.2. Market Size by Therapies in EU4 and the UK 12.8. Japan 12.8.1. Market Size by Indications in Japan 12.8.2. Market Size by Therapies in Japan 13. KOL Views 14. Unmet Needs 15. Market Access and Reimbursement 16. Appendix 16.1. Bibliography 16.2. Report Methodology 17. DelveInsight Capabilities 18. Disclaimer 19. About DelveInsight Related Reports Migraine Market Migraine Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key migraine companies, including Lundbeck Seattle BioPharmaceutical, Eli Lilly and Company, Amgen, Novartis, Teva Pharmaceuticals, Allergan, Biohaven Pharmaceuticals, Dr. Reddy's Labs, AbbVie, Impel NeuroPharma, Zosano Pharma, Axsome Therapeutics, Aeon Biopharma Inc., Ionis Pharmaceuticals, Inc., Charleston Laboratories, among others. 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Peripheral T-Cell Lymphoma Market Peripheral T-Cell Lymphoma Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key PTCL companies, including Secura Bio, Shanghai YingLi Pharmaceutical, Dizal Pharmaceuticals, Viracta Therapeutics, Innate Pharma, CStone Pharmaceuticals, Affimed, Otsuka Pharmaceutical, Astex Pharmaceuticals, Autolus, Myeloid Therapeutics, Merck Sharp & Dohme, Bristol Myers Squibb, among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve. Contact Us Shruti Thakur info@ +14699457679 Logo: View original content:

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