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New study finds ‘simple selfie' can help predict patients' cancer survival

New study finds ‘simple selfie' can help predict patients' cancer survival

Irish Examiner09-05-2025
A selfie can be used as a tool to help doctors determine a patient's 'biological age' and judge how well they may respond to cancer treatment, a new study suggests.
Because humans age at 'different rates' their physical appearance may help give insights into their so-called 'biological age' – how old a person is physiologically, academics said.
The new FaceAge AI tool can estimate a person's biological age, as opposed to their actual age, by scanning an image of their face, a new study found.
Our study now has shown for the first time that we can really use AI to turn a selfie into a real biomarker source of ageing.
A person's biological age, which is a predictor of their overall health and can be a predictor of life expectancy, is based on many factors including lifestyle and genetics, researchers from Mass General Brigham in the US said.
But they wanted to examine whether or not biological age could be examined based on how a person looks – similar to what doctors call an 'eyeball test' whereby certain judgments are made based on how a person looks, such as whether or not someone could undergo intensive cancer treatment based on how frail they appear to be.
Researchers said they wanted to see whether they could 'go beyond' the 'subjective and manual' eyeball test by creating a 'deep learning' artificial intelligence (AI) tool which could assess 'simple selfies'.
The new algorithm was trained using 59,000 photos.
Actor Paul Rudd's biological age appeared to be much lower than his actual age (PA)
'Our study now has shown for the first time that we can really use AI to turn a selfie into a real biomarker source of ageing,' said Dr Hugo Aerts, corresponding author of the paper.
He said the tool is low cost, can be used repeatedly over time and could be used to track an individual's biological age over 'months, years and decades'.
'The impact can be very large, because we now have a way to actually very easily monitor a patient's health status continuously and this could help us to better predict the risk of death or complications after, say, for example, a major surgery or other treatments,' he added.
Explaining the tool, academics showed how it assessed the biological age of actors Paul Rudd and Wilford Brimley based on photographs of the men when they were both 50 years old.
Rudd's biological age was calculated to be 42.6, while Brimley, who died in 2020, was assessed to have a biological age of 69.
The new study, published in the journal Lancet Digital Health, saw the tool used on thousands of cancer patients.
Wilford Brimley's face was used in the study (Alamy/PA)
FaceAge was used on 6,200 patients with cancer using images taken at the start of their treatment.
The academics found that the biological age of patients with cancer was, on average, five years older than chronological age.
They also found that older FaceAge readings were associated with worse survival outcomes among patients with cancer, especially in people who had a FaceAge older than 85 years old.
The authors concluded: 'Our results suggest that a deep learning model can estimate biological age from face photographs and thereby enhance survival prediction in patients with cancer.'
Dr Ray Mak, co-senior author on the paper, added: 'We have demonstrated that AI can turn a simple face photo into an objective measure of biological age, that clinicians can use to personalised care for patients, like having another vital sign data point.'
He said that it is 'another piece of the puzzle like vital signs, lab results or medical imaging'.
But he added: 'We want to be clear that we view AI tools like FaceAge as assistance provide decision support and not replacements for clinician judgment.'
More studies assessing FaceAge are under way, including whether it could be used for other conditions or diseases and what impact things like cosmetic surgery or Botox have on the tool.
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Advertisement 16 In 2024, she was also diagnosed with functional neurological disorder Credit: Jam Press/@leanne_fighting_ms 16 Leanne shares her experiences, including seizures, on social media Credit: Jam Press/@leanne_fighting_ms 16 Leanne had no idea multiple sclerosis would affect her sex life Credit: Jam Press/@leanne_fighting_ms 'There's been many times my partner could've walked away, but he says we are a team. 'He knows the severe change is because of my MS and the full extent of life with it. Advertisement 'I spoke with an MS neurologist in front of him about the issues we were having in the bedroom and he understood that it's not him, it's my brain. 'Now, we have sex a few times a week – but he knows when not to try his luck. 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FUNCTIONAL neurological disorder is a 'brain network disorder,' according to UK charity FND Action. The brain is unable to send and receive messages correctly, affecting all parts of the body. Some symptoms, particularly if not treated, can result in substantial disability. Treatment includes 'retraining' the brain with specialised physiotherapy, distraction techniques and psychotherapy. But some 70 per cent of sufferers have the same or worse symptoms ten years later. The exact causes of FND are unknown. Symptoms can appear suddenly after a stressful event or with emotional or physical trauma, including a head injury, migraine, surgical procedure or vaccination. It can occur as a result of several factors working together, for example, the brain shutting down after perceiving a threat or trying to avoid pain as well as a genetic vulnerability to the condition. It is estimated that up to 120,000 people in the UK have FND, and there are a further 10,000 new cases per year, according to The Brain Charity. But most people have never heard of it. 16 'I've gone from walking three miles every day to almost being bedridden,' Leanne says. Credit: Jam Press/@leanne_fighting_ms 16 Leanne and Adam now have sex a few times a week Credit: Jam Press/@leanne_fighting_ms 16 She often has leg spasms which make her whole body shake Credit: Jam Press/@leanne_fighting_ms Advertisement 16 The brain scan which revealed Leanne's MS (as shown by white spots) Credit: Jam Press/@leanne_fighting_ms 16 Leanne having treatment in hospital Credit: Jam Press/@leanne_fighting_ms

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