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Blood test can detect cancer 18 months before symptoms appear

Blood test can detect cancer 18 months before symptoms appear

Yahooa day ago

A new blood test means it is now possible to detect cancer up to 18 months before symptoms even appear. Test for Cancer has launched the HrC Genomics blood test, a non-invasive screening tool designed to spot cancer before it becomes symptomatic, reducing the need for invasive procedures like tissue biopsies.
With cancer among the world's leading causes of death, early detection remains one of the most effective ways to improve outcomes. But many cancers are diagnosed too late, when treatment options are more limited and survival rates are lower.
Test for Cancer says its new test can change that. By identifying specific stem cells that begin circulating when cancer is present, even before symptoms emerge, the HrC Genomics test offers a way to screen for cancer much earlier than standard approaches allow.
READ MORE: Cardiologists name two foods that lower cholesterol 'just like statins'
READ MORE: Neurologist says you can cut cholesterol, blood pressure and dementia risk in 20 minutes
According to the organisation, these cells, known as pluripotent progenitor stem cells, can be detected in the blood as early as 12 to 18 months before any signs of illness. That early window gives patients and doctors more time to intervene and improves the chances of successful treatment.
The test is available to adults of all ages and is not limited by gender or family history, making it a potentially powerful screening option for people who might not otherwise qualify for routine checks. Test for Cancer says its mission is to make early cancer detection more widely accessible, helping more people take control of their health and catch cancer before it advances.

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Primary Sclerosing Cholangitis (PSC): Diagnosing and Living With This Liver Condition
Primary Sclerosing Cholangitis (PSC): Diagnosing and Living With This Liver Condition

Health Line

timean hour ago

  • Health Line

Primary Sclerosing Cholangitis (PSC): Diagnosing and Living With This Liver Condition

Primary sclerosing cholangitis (PSC) affects the liver and bile ducts. Symptoms and treatment vary from person to person. PSC is a rare liver disease that affects the bile ducts. It's progressive, which means it gets worse over time. Treatment includes taking certain medications, including antibiotics, undergoing procedures to address blockages, and — in cases of liver failure — receiving an organ transplant. Here's what you need to know about PSC, its symptoms, and the outlook with proper treatment. What is primary sclerosing cholangitis? The liver is an organ in your body that breaks down food into its essential nutrients (proteins, fats, etc.) and energy, vitamins, and minerals. It also works to remove toxins from the bloodstream and assists in the digestive process by making a fluid called bile. More specifically, the bile ducts in the liver are responsible for transporting digestive juices (bile) from the liver to the small intestine and gallbladder. Bile helps break down fats and fatty vitamins in these organs and further aids digestion. With PSC, inflammation causes damage in the form of scarring, also called fibrosis. The scarring narrows and eventually blocks the bile ducts. When the ducts are blocked, the bile cannot travel where it needs to go. This results in liver damage. How many stages of primary sclerosing cholangitis exist? There are four stages of PSC: Cholangitis or portal hepatitis: With cholangitis, scarring is limited to the portal areas of the liver. Periportal fibrosis or periportal hepatitis: Areas of scarring extend beyond the portal areas but do not yet connect. Septal fibrosis, bridging necrosis (or both): Areas of scarring begin to connect to one another. Biliary cirrhosis: Scarring forms 'honeycomb' shapes and becomes more widespread. You may not have any symptoms or only mild signs in the beginning stages, so any symptoms you're experiencing do not necessarily relate to the stage of PSC. That said, symptoms tend to get more severe with each stage and continued damage to the liver. What causes primary sclerosing cholangitis? Doctors don't know exactly what causes PSC. And what causes it may be different for different people. What they do know is that: Some 70% of people who are affected are men, primarily young and middle-aged men. Around 80% of people with PSC also have inflammatory bowel disease. Several factors may increase your risk, like having certain viral or bacterial infections or a family history of the condition. What are the symptoms of primary sclerosing cholangitis? You may not have symptoms in the early stages of PSC. Some people may be asymptomatic or only have mild symptoms for the first few years. If you do have symptoms, they may come and go and get worse as the condition progresses. Possible symptoms include: fatigue itchy skin (pruritus) yellow skin and eyes (jaundice) fever, chills nausea abdominal pain (upper right) weight loss dark-colored urine, light-colored stools vitamin deficiencies enlarged liver or spleen If you're experiencing any concerning symptoms, make an appointment with a primary care doctor. They may refer you to a liver specialist called a hepatologist for more detailed testing and treatment. How is primary sclerosing cholangitis diagnosed? Signs of PSC may show up as abnormal results on liver blood tests. A more concrete diagnosis can be made after an liver MRI or a test called a cholangiography, where contrast dye is injected into the bile ducts and then viewed on an X-ray. How do you treat primary sclerosing cholangitis? To treat PSC, doctors will first personalize treatment by focusing on the symptoms a person is experiencing. The main goal of treatment is not to cure the condition but to slow its progression. Treatment options include: Medications: Your doctor may prescribe antibiotics to prevent infection or manage inflammation. Other medications include cholestyramine to help manage skin itching and bisphosphonates to protect bone mass and treat osteoporosis. Surgery: You may have endoscopic surgery to remove blockages in the bile ducts or widen narrowed ducts. Lifestyle changes: You may need to reduce or avoid your alcohol intake and quit smoking to further protect your liver. Eating a balanced, nutritious diet and taking supplements may also help address nutritional deficiencies. Vaccination: Your doctor may recommend getting vaccinated against both hepatitis A and B to provide extra protection for your liver. A liver transplant may be necessary in the later stages of PSC. This is usually around 10 years after diagnosis. Examples of later-stage complications might include: itching that is difficult to manage recurrent bacterial cholangitis end stage liver disease liver failure Liver transplants are generally effective in treating PSC, and many people go on to have a full, healthy life. However, it's also possible for PSC to come back, even with a transplant. Does the NHS cover primary sclerosing cholangitis liver procedures? The National Health Service (NHS) in the United Kingdom provides universal healthcare. The NHS generally pays for both inpatient and outpatient hospital care, which may include liver procedures and transplants. Still, there is no legislation or ' absolute right ' to specific care of any kind. It's important to check with your hospital for details on the coverage provided for you and your procedure. The average time a person waits for a liver transplant in the United Kingdom is between 5 and 7 months. This time may be shorter or longer depending on organ availability and your health status. Is primary sclerosing cholangitis covered by insurance plans in the United States? In the U.S., many insurance plans cover the basic treatments and prescription medications that might come with PSC. Of course, insurance plans vary, so it's important to know what your plan formulary allows. Most insurance companies also cover liver transplants, though it's important to check with your carrier to verify that coverage and your out-of-pocket costs. What's the long-term outlook for primary sclerosing cholangitis? Without treatment, people with PSC may experience: liver failure frequent infections certain cancers Both bile duct cancer (cholangiocarcinoma) and gallbladder cancer are two types of cancer that are more likely to occur in people with PSC. Again, this condition is progressive, so it tends to worsen over time. Treatment may slow the progression and treat symptoms, but a liver transplant is often necessary. The outlook for people who have undergone a liver transplant for PSC is favorable. Around 80% survive beyond 2 years after surgery with a good quality of life. Takeaway PSC is a rare, progressive liver disease that affects the bile ducts. Symptoms can vary in intensity and may include fatigue, itching, and yellowing skin and eyes. If you're experiencing any symptoms that concern you, make an appointment with a primary care doctor. They may refer you to a hepatologist for tests and treatments. There are various treatments for PSC, depending on the stage and symptoms you're experiencing. Some people with PSC may need a liver transplant around 10 years after their diagnosis. After a transplant, many people go on to have a good quality of life.

New MIT tech turns desert air into safe drinking water
New MIT tech turns desert air into safe drinking water

Fast Company

time2 hours ago

  • Fast Company

New MIT tech turns desert air into safe drinking water

An innovative and potentially impactful new device can turn air into drinkable water, even in the driest climates. The tool, which comes from researchers at MIT, could be a huge step towards making safe drinking water worldwide a reality. Lack thereof impacts 2.2 billion people, per a study on the invention, which was recently published in journal Nature Water. The device was developed by Professor Xuanhe Zhao, the Uncas and Helen Whitaker Professor of Mechanical Engineering and Civil and Environmental Engineering at MIT, and his colleagues. According to the study, the contraption is made from hydrogel, a material that absorbs water, and lithium salts that can store water molecules. The substance is enclosed between two layers of glass, and at night, pulls water vapor from the atmosphere. During the day, the water condenses and drips into tubes. It's is about the size of a standard window, but even in environments that are hot and dry, it's able to capture water. Zhao's team tested the tool in the driest environment in the U.S. — Death Valley, California. Even in the ultra-dry conditions, the tool was able to capture 160 milliliters per day (about two-thirds of a cup). The success of the model has the scientists thinking on a bigger scale. 'We have built a meter-scale device that we hope to deploy in resource-limited regions, where even a solar cell is not very accessible,' says Xuanhe Zhao, per MIT News. Zhao continued, 'It's a test of feasibility in scaling up this water harvesting technology. Now people can build it even larger, or make it into parallel panels, to supply drinking water to people and achieve real impact.' The new design addresses several issues that past similar devices have come up against. It's better at absorbing water than metal-organic frameworks (MOFs) that can also capture water from air. The new design, which has a sophisticated composition and added materials, is also better at limiting salt leakage. During the experiment, that meant that the water collected met criteria for safe drinking water. 'We imagine that you could one day deploy an array of these panels, and the footprint is very small because they are all vertical,' says Zhao. 'Then you could have many panels together, collecting water all the time, at household scale.'

Medicare Part D: Does Medicare Cover Dovonex​?
Medicare Part D: Does Medicare Cover Dovonex​?

Health Line

time2 hours ago

  • Health Line

Medicare Part D: Does Medicare Cover Dovonex​?

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