
Urgent warning over lethal 'super fungus' as expert predict it could kill NINE MILLION
Aspergillus, a type of mould, is all around us—in the air, soil, food and in decaying organic matter.
But if spores enter the lungs, the fungi can grow into a lumps the size of tennis balls, causing severe breathing issues—a condition called aspergillosis.
The infection can then spread to the skin, brain, heart or kidneys, and kill.
Researchers say a rise in global temperatures is fueling the growth and spread of aspergillus across Europe, increasing the risk of the deadly illness.
Invasive fungal infections such as aspergillosis are already estimated to cause at least 2.5 million deaths globally each year.
University of Manchester experts Professor Norman Van Rhijn, co-author of the study, told the Financial Times that the world is nearing a 'tipping point' in the spread of fungal pathogens.
He added: 'We're talking about hundreds of thousands of lives, and continental shifts in species distributions.
'In 50 years, the things that grow—and the things that infect us—will be completely different.'
While most people don't get sick from inhaling aspergillus spores, infections are becoming increasingly difficult to treat once they take hold.
People with weakened immune systems—due to conditions such as asthma, cystic fibrosis or diabetes, or as a result of treatments like chemotherapy—are at significantly higher risk.
New research suggests that Aspergillus fumigatus, already present in the UK, could spread across large parts of northern Europe, Asia, and the Americas.
Within the next 75 years, it could even reach as far as the North Pole, potentially exposing an additional nine million people to infection.
This species thrives in warm compost—an environment that may have helped it adapt to the human body's internal temperature of around 37°C.
Another species featured in the study, Aspergillus flavus, is also cause for concern.
Also linked to rising global temperatures, it produces aflatoxins—chemicals associated with cancer and severe liver damage.
Scientists believe higher temperatures and CO₂ levels are accelerating the production of these dangerous toxins.
Darius James, professor of infectious diseases at Imperial College London, told the FT: 'There are serious threats from this organism both in terms of human health and food security.'
According to the study, the spread of the fugus could eventually wipe out existing habitats in African countries and Brazil, disrupting eco systems that are vital to life.
Recent data also suggests that the pathogen could become resistant to treatment.
This is due primarily to the overuse of anti-fungal drugs in medicine and agriculture, which has encouraged more toxic strains of the fungus to evolve that are resistant to high doses of the drugs, known as azoles.
Fungi also reproduces and evolves far quicker than humans. This means, the more these organisms come into contact with antifungal drugs, the more likely it is that resistant strains—or super-fungi—will emerge.
Another trigger is the use of human antifungal treatments to protect crops and plants from fungal diseases. Many of the fungi which infect humans also live in soil, which, when they come into contact with such chemicals, provides further opportunity for the creation of these super-fungi.
Viv Goosesns, research manager at Wellcome, said climate change will only make these risks worse, resulting in more infections in healthy people.
She said: 'Fungal pathogens pose a serious threat to human health by causing infections and disrupting food systems.
'Climate change will make these risks worse. To address these challenges, we must fill important research gaps.
'By using models and maps to track the spread of fungi, we can better direct resources and prepare for the future.'
Despite this urgent appeal, fungal infection research and treatment is alarmingly underfunded. According to the study, fewer than 10 per cent of an estimated 1.5 to 3.8million species have been identified.
Wellcome Trust is dedicating over £50million in funding towards fungal research over the next year.
This new research comes following an outbreak of A. fumigatus in 2021 which infected the weakened lungs of Covid patients in intensive care, killing up to 70 per cent of those affected.
Earlier this year, Matthew Langsworth, 32, from Leamington Spa was hospitalised by a life-threatening blood infection caused by invasive aspergillus, after living in a fungus-infected property where spores were covered up with paint.
Living in mouldy properties is known to cause a range of health problems including respiratory infections like aspergillus, asthma and allergies.
Mould — a microscopic fungus — causes these conditions by releasing thousands of microscopic toxic particles into the atmosphere.
Signs that you may be affected by household mould include a prolonged cough, wheeze or feeling short of breath.
Other symptoms include worsening of asthma and other respiratory conditions or those that involve the inflammation of the airways.
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Telegraph
4 days ago
- Telegraph
First woman appointed Astronomer Royal
A woman has been appointed Astronomer Royal for England for the first time in history. Prof Michele Dougherty will take on the prestigious role after the retirement of Lord Martin Rees, who held the position for 30 years. The title Astronomer Royal has been awarded to a leading expert in the field for 350 years, and has had 15 separate holders in this time. The honorary role involves a duty to inform the monarch of astronomical matters. The position was first created in the 17th century by Charles II as a way to discover a way to determine longitude at sea when out of sight of land, 'for perfecting the art of navigation'. John Flamsteed, a Derbyshire astronomer, was the inaugural Astronomer Royal and also made the first recorded observations of Uranus. He laid the foundation stone of the Royal Observatory in Greenwich, where the Astronomer Royal is based to this day. 'I am absolutely delighted to be taking on the important role of Astronomer Royal,' said Prof Dougherty. 'As a young child I never thought I'd end up working on planetary spacecraft missions and science, so I can't quite believe I'm actually taking on this position. 'In this role I look forward to engaging the general public in how exciting astronomy is, and how important it and its outcomes are to our everyday life.' Prof Dougherty is professor of space physics at Imperial College London, and her research focuses on the magnetic field interactions of planets, especially those of the gas giants, Saturn and Jupiter. She was the principal investigator of the magnetometer on Nasa's Cassini spacecraft mission, which analysed data of Saturn's magnetic field. Prof Dougherty's work led to the discovery of water vapour around the Saturnian moon Enceladus, thereby showing it could harbour life. Prof Dougherty also worked on the Galileo mission to Jupiter, and the current Juice mission to the Jovian moons Europa, Callisto and Ganymede, which is scheduled to arrive in 2032. When Juice launched in 2023, she said the project was trying to detect tiny magnetic fluctuations, which is 'like trying to find lots of needles in a haystack, and those needles are changing shape and colour all the time'. She has been instrumental in furthering humanity's knowledge of the solar system and is highly decorated with awards and recognition, including the Hughes Medal, a CBE, and being elected as a Fellow of the Royal Society. Women in Stem Prof Dougherty has also spoken about the importance of inclusion and diversity in science, particularly around the value of women in Stem fields. In 2022, she criticised headteacher Katharine Birbalsingh for saying that girls shun physics at A-level because of an aversion to 'hard maths'. Prof Dougherty said at the time: 'We have worked incredibly hard in the UK in recent years to ensure that anyone who is interested in studying physics feels supported and enabled to do so, and this is something we will continue to focus on. 'I am so very proud of all that my students and staff achieve as they carve out their careers – irrespective of their gender. It is astounding to me that senior leaders in the UK continue to make such unbelievably stereotypical comments, which are not backed up by data.' Prof Dame Angela McLean, the Government Chief Scientific Adviser, said: 'Warm congratulations to Prof Michele Dougherty on her appointment to the distinguished position of Astronomer Royal. This is a fitting recognition of her outstanding work and enduring commitment to the field of astronomy.'


The Guardian
4 days ago
- The Guardian
Colonial ideas of beauty: how skin lightening products are linked to cancer in black African women
Two months after first going to hospital, a 65-year-old woman was dead – and her doctors are blaming the cosmetic creams she used on her face and body for decades. The anonymous patient, from Togo, is one of a string of recent cases reported in medical journals of cancers in black African women linked to skin-lightening creams and lotions, prompting dermatologists to call for better regulation. The melanin found in darker skin typically offers some protection against the sun damage which can cause cancers. 'Patients with black skin have a natural SPF of about 15, just by having pigmented skin,' says Prof Ncoza Dlova, head of dermatology at the University of KwaZulu-Natal, South Africa,. 'If they remove that melanin [with skin lightening creams], they're actually removing the natural protection.' Estimates of skin lightening product use in African countries range from 25% to 80% of women. Lighter skin is often seen as more desirable, in a trend with complex drivers including values imported in the colonial era. Dlova and colleagues are writing up a paper citing more than 55 cancer cases, from countries including Mali and Senegal. 'If we are getting self-induced skin cancer, then that's a red flag and worrying,' says Dlova. 'We have to do something about it.' The market for skin lightening product is growing, with analysts predicting that the current market size of US$10.7bn (£8bn) will reach US$18.1bn by 2033. There are even reports of the products being used on babies and young children. For Dlova, they are 'a health hazard that needs to be addressed'. Almost every day, she says, her clinic in Durban will see someone with a skin problem linked to lightening products. 'Of course, not all of them are coming with skin cancer … They come in with fungal infections that are resistant to the common treatment that we normally use. They present with pimples, referred to as steroid-induced acne, as well as rosacea. Some present with permanent stretch marks; all these complications are extremely common.' The Togo patient had three large, painful, cancerous tumours on her neck, which she had tried to treat with antibiotics, antiseptics and traditional herbal poultices with no success before going to hospital. One of the tumours was removed, but the others were too close to blood vessels and she could not afford the recommended chemotherapy. She told her doctors she had used creams that included topical hydroquinone and highly potent corticosteroids for about 30 years. In another series of eight cancers, reported in Senegal, the women had used similar products for about 20 years on average. Two of those patients died. Hydroquinone as a skin lightener has been banned in South Africa since 1990, and other African countries including Rwanda, Ivory Coast, Tanzania, Kenya, and Ghana followed suit. Those bans were prompted by serious concerns about an irreversible form of skin damage called ochronosis. But regulation is often weak, and the products are reportedly still available from street vendors and cosmetic shops. The use of steroids in skin lighteners is a newer phenomenon. Topical steroids are used in dermatology to treat inflammatory skin conditions such as eczema, but a side-effect is that they make skin lighter, a fact exploited for their use in cosmetics. If the two problematic ingredients are used together they can have a 'synergistic effect', Dlova says. The International League of Dermatological Societies (ILDS) has published an alert warning about the dangers of misuse of potent topical steroids, and is calling for governments to better regulate the products. The problem goes beyond Africa, says the ILDS president Prof Henry Lim, with the problem first raised by its members in India. After South Africa's hydroquinone ban, there was a lull in how frequently dermatologists encountered complications of skin bleaching, Dlova says 'but again, in the last 10 years there was just a sudden eruption of the complications of skin bleaching again. Skin cancer per se had not been described before, it's only been described recently. So obviously, things have got worse – because from irreversible pigmentation [ochronosis] to skin cancer, those are really red flags implying that we need to do something about it.' While the desire for lighter skin is not new, Dlova suspects the rise of social media over the past decade has led to increased use, pointing to smartphone filters that make skin look smoother and lighter. Tackling the issue will require action from many sectors – not only regulatory agencies. 'Marketing, social media and media all have a role to play – fashion, celebrities and all of that. If they use black models who are lighter in skin colour, the message they are conveying is that you are prettier, you can be a model, you are more attractive if you are lighter. So we need to ensure that the advertisements include diverse skin colours when they are choosing their models,' says Dlova. She also wants to see skin health education in preschools to teach children to be proud of their natural skin, and to get across the message of using sunscreen. Some black patients will have skin challenges including pigmentation disorders, she says, which may require creams with lightening ingredients. But these should be used under medical supervision. Part of the ILDS advocacy will be asking pharmaceutical companies to make those prescription products more affordable, so that people do not need to turn to cheaper off-the-shelf products that may be dangerous.


Telegraph
25-07-2025
- Telegraph
Robert Winston: ‘Striking doctors have lost the plot and the trust of the nation'
Robert Winston's impeccable bedside manner does not lend itself to expressions of anger, but there is no mistaking his disgust as he decries the 'highly immoral' doctors' strike beginning on Friday. After six decades in medicine, Prof Lord Winston is better qualified than almost anyone in the country to assess the current state of the NHS and the impact the strike will have on it and its patients. There is no doubt in his mind that people will die as a result of the five-day walkout – for which he cannot forgive his colleagues – but he foresees a much longer-term malaise taking root in the NHS because of the industrial action. 'I think it's very, very obvious that my colleagues, the resident doctors, have lost the plot, and more importantly probably lost the trust of the nation,' he says, 'and I think it's going to be very difficult to get that back.' A professor of science and society at Imperial College London, Lord Winston is a fertility expert who pioneered key advancements in IVF treatment. However, it was the groundbreaking BBC documentary series he presented – including Your Life in Their Hands, The Human Body and Child of Our Time – that made him a household name. He is also a Labour peer. Celebrated for his calm, authoritative persona, which remains steady even during a clinical dissection of his younger colleagues' behaviour, his message becomes all the more powerful. Earlier this month, he resigned his membership of the British Medical Association (BMA) after 61 years, mainly due to his disgust at the proposed strikes, but also because of its failure to tackle rising anti-Semitism among NHS doctors, of which more follows. The strike is an attempt by the BMA to force the Government into giving residents (previously known as junior doctors) a pay rise of 29 per cent, on top of increases of 22 per cent and 5.4 per cent over the past three years. Lord Winston does not mince his words when I ask him how much danger patients will be in because of the strike. 'It's very likely if this lasts at all long, somebody will die,' he says. 'Inevitably they will. You can't avoid it. 'Several people clearly are going to have much worse chances of getting their cancers treated, and some people will be less well or in pain. You can't simply allow disruption of services on this scale, and not accept the fact that more accidents will happen.' Trust in the NHS will be eroded, and Lord Winston believes that trust is not only important in determining the level of public support for the strikes but also has a direct effect on patients' health. 'That is an important part of treatment because if people trust you and they feel they're getting good medicine, they tend to get better because of what we call a placebo effect, which actually is not insignificant,' he says. 'It's been shown again and again that that attitude to your medicine plays a major role in how you heal. If you're reasonably happy and reasonably sure of your treatment, what studies have shown is that your symptoms get less and your treatment tends to be quicker.' The doctors' union, Lord Winston says, 'does not represent a very large proportion of the medical profession' anymore, and is 'acting highly politically' under the chairmanship of Dr Thomas Dolphin, a militant Corbynista who tried, and failed, to be selected as a Labour Party candidate at the last election. Lord Winston is not convinced that the strikes have as much support among resident doctors as it might seem; he believes many have been 'pressurised' into backing strike action by a union attempting to 'blackmail' the Government. 'At this time when people are struggling in all walks of life, in all professions, particularly with the difficult financial situations we have, I think that's pretty dishonourable. But more importantly, I don't think doctors should strike.' Lord Winston is now 85 but still has a full head of dark hair and a jet-black moustache, and retains all the sharpness and vigour of a man half his age. 'It's probably all genes,' he chuckles when I ask how he stays looking so young. 'I don't live particularly well. I drink too much alcohol.' He is speaking from the kitchen of his home in north-west London, where he lives alone following the sudden death of his wife Lira four years ago, after 48 years of marriage. Lord Winston obtained his medical degree in 1964 and made a career as an expert in fertility. As professor of fertility studies at Hammersmith, he led the IVF team that pioneered pre-implantation genetic diagnosis to identify defects in human embryos. He remains professor of science and society at Imperial College London and its emeritus professor of fertility studies, and is a founding member of the UK-Israel Science Council. He is old enough to remember the formation of the NHS, has worked within it for most of its history, and is not afraid to say that it needs to change to survive. He points out that when the NHS was founded in 1948, the per-patient cost each year was around 10s 6d, which translates to about £100 in 2025, adjusted for inflation. Today's per-patient cost is around £3,000, meaning it is time to discuss a new way of funding the NHS, Lord Winston says. He does not offer a ready-made alternative funding model, but says that if the NHS were a factory producing goods, the manager would know the cost price of everything it did, whereas 'we don't know any of that in the NHS'. The biggest cost within the NHS, of course, is wages, and student doctors entering the profession today need to be realistic about what to expect, both in terms of pay and conditions when they first begin working, he suggests. 'When I talk to medical students, which I do very frequently, I make it very clear that the NHS is not an easy place to work in,' he says. 'When I first got on the wards, I made a terrible mistake on the first day – almost killed a patient by injecting something. 'I say, look, this is difficult, but in the long term it's still worth doing.' Successive governments are partly to blame for the current dissatisfaction among some NHS staff, he says, but from a financial point of view, medicine remains a lucrative profession for doctors who rise through the ranks. 'I didn't get my first house until 10 years after I qualified. It is a problem, but in the long term it's a pretty secure job and you can do a lot of things with it. And you can earn in all sorts of ways if you want to.' Despite being a Labour peer with expertise in health, he says he has never met Wes Streeting, the Health Secretary, but believes 'he is absolutely right to be looking at all sorts of options' to end the doctors' dispute. Streeting thinks there is a deal to be done on the cost of exams, equipment and training. Lord Winston says he does not understand why the doctors refuse to consider the offers being made, unless the BMA is purely motivated by a desire to challenge the Government – 'and I think that's a dangerous thing to do.' Another way in which the BMA appears to have become politicised, he says, is over the issue of anti-Semitism in the workplace. Lord Winston, who was brought up as an Orthodox Jew, says this was part of the reason he quit the BMA. Some Jewish doctors have reported feeling 'intimidated and unsafe' at the BMA's annual conference because one in 10 motions relate to Israel, Palestine or Zionism. The union has also been accused of allowing members to cross the line from expressing political opinions into singling out Jewish colleagues. Is that fair criticism? 'I've had a number of letters from colleagues who have raised that issue with me,' he says. 'There are lots of areas where the BMA is failing. Anti-Semitism certainly is something that I know a lot of Jews have been worried about, and sometimes I've seen pretty horrific things that are still going on and not properly dealt with.' He says one of the problems he keeps hearing complaints about is NHS workers conflating being Jewish with being Israeli, meaning 'you're responsible for the Israeli government and the appalling things which are happening in the Middle East'. 'I've seen many people who've been very unpleasantly criticised for something which is no fault of theirs simply because they're Jewish.' He has come to the conclusion that the BMA, which has not even bothered responding to his attempts to engage with it, is 'not fit for purpose'. Last year, Dr Dolphin put forward a motion, passed without debate, to reject the independent Cass review into children's transgender services, which called on the NHS to stop prescribing puberty blockers to minors. Lord Winston, who believes people cannot change their biological sex through surgery or any other means, was an outspoken supporter of the gender-critical academic Kathleen Stock, who was sacked by the University of Sussex in 2021. 'The BMA haven't done very well on that either,' Lord Winston says. 'They've ended up with a very muddled appraisal of transgender, which doesn't make any kind of scientific sense. And of course, transgender is a massive problem because people who are transgender are now really quite at risk. 'How we deal with this, of course, has to be a scientific solution to some extent until we understand why people want to be transgender or end up being transgender […] I know from my own clinic I saw quite a few patients who had changed their sex, or had transgender procedures, who then regretted what had happened later on. 'One of the things we do need to have is real sensitivity towards people who are in this situation, and towards the families too, who often have difficult relationships with their own children as a consequence. That needs to be dealt with. I don't think the BMA has made a great attempt at doing that. 'It would be very helpful if we had a proper discussion which is based more on the science and the medicine than the attitudes.' Another emotive subject facing politicians at the moment is assisted dying. Kim Leadbeater MP's bill to legalise it is currently on its way through the House of Lords, and Lord Winston will be speaking when it is debated later this year. He says that, having initially been against the bill, he is now leaning towards supporting it. 'I'm massively coming around to the fact that we're behind the curve in this country because […] there are many, many countries now that have some form of legislation. 'And it seems to me that there are certain situations where people really have a right to take some kind of elixir that, in fact, allows them to be finally free of pain. 'Of course, I want to see more palliative care, but one of the problems is that many of those most opposed have strong religious views. That's a dangerous position to take if you're a parliamentarian, because you're legislating for the whole community, not just people of your own faith.' For that reason, he abstained from the last vote on the bill in the Lords, but says he has tried to imagine what he would want if he were in the position of terminally ill patients seeking control over their own death. He draws on personal experience, recalling his time working for a GP to earn extra money during holidays from his hospital residency. The GP told him that a terminally ill lung cancer patient must not be admitted to hospital under any circumstances 'because he wants to stay in his own surroundings'. Lord Winston was told to visit the man every day, and in the end 'he died very peacefully' in his own home. He also brings up the case of Herbie Mowes, the German antiques dealer who made history by allowing the BBC to film his death from cancer for Lord Winston's documentary series The Human Body in 1998. The BBC, he recalls, 'wanted to abandon the programme' after the press derided it as a 'snuff video,' but after it was broadcast, it helped to change attitudes towards death, he says. Herbie 'was content with his garden, his little house, and his friends,' and his GP visited twice a week to adjust his medication. A large crew worked on the documentary, he says, and 'I think they often changed their view about dying afterwards'. It would be remiss not to ask the country's foremost expert on fertility for his views on the latest developments in IVF and genetics. When I ask him for his views on this month's controversy over 'three-parent babies'– in which the nucleus of a fertilised egg is transferred into a donor egg to avoid a type of genetic disease – he points out that he fought for the procedure to be legalised during a Lords debate a decade ago. He dismisses criticism of the procedure, which has been pioneered by Newcastle University, saying that it is only really the 'battery pack' in human cells that is being altered. But it does raise a much wider question: would it be right for science to eradicate disability altogether if it were possible? 'No,' he says, 'but we couldn't, because when it comes to genetic disease, many genetic diseases occur between generations. 'So we're going to continue to get genetic disease, even with screening, even with the ability to change DNA in embryos.' The future of medicine, he says, 'is not really in our genes, it's in how we improve people's environment'. Better education and higher living standards, he believes, will have a greater impact on world health than the DNA inside embryos. As for his own living standards, he mentions that he could have chosen to settle in America, where he was paid 'a huge salary' with much better funding for his research during a spell there in the early 1980s, but he cannot live without London's art galleries and its classical music and opera scene. His other passion in life, aside from his three grown-up children and eight grandchildren, is his wine collection, which he started building up as an undergraduate, with a particular love of burgundies – 'unpredictable and often unrepeatable,' in his words. 'I recently drank one from 1919,' he says, 'which I bought for a couple of quid a long time ago and which would now be valuable at auction. 'But I'm not interested in trying to sell wine. What I like is to sit around and drink it with friends.' Likewise, Winston's medical career has never been about the money – and he seems to wish that today's resident doctors would adopt the broader view that has guided him throughout his career. He believes that 'doctors have a huge moral obligation'. 'They're sitting in front of somebody they don't know very well,' he says, 'but who is actually opening themselves up in a very private way, in a way they don't really want to. 'They're often in pain. They're often very worried. They often think they have something much worse than they really do. They're about to undergo all sorts of humiliating tests and investigations. They're in hospital, away from their family. They're worried about money, they're worried about their family. 'A doctor has a unique privilege. Nobody else in the world has that privilege. And I want to say that to them because, if you abuse that privilege, you run great risks with the relationship you then have with the patient afterwards.'