What Brands Should Know About Forthcoming Canadian, US PFAS Regulations
They've also been linked to manifold risks to human health and the environment. Whether used as a part of a manufacturing process or as an additive in a finished product, PFAS has been found in groundwater, drinking water and different bodies of water accessible to humans. According to the U.S. Environmental Protection Agency (EPA), exposure may lead to reproductive effects and interference with hormones, developmental delays in children, certain cancers, and immune system damage.
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With these issues as a backdrop, the Canadian Apparel Federation and Marten Law hosted a webinar Wednesday dedicated to understanding the recent governmental intervention when it comes to companies' use of PFAS.
James Pollack, who leads Marten Law's consumer products regulatory practice, laid out the legislative continuum when it comes to regulation. The first set of products that became the focus of PFAS bans were children's products, and the next tranche of prohibitions focused on cookware, with the idea that PFAS might move from cooking surfaces or packaging into food.
'What's interesting is the next set of products that became a focus for folks was textiles, including apparel and footwear. And I think part of it is this visceral sense of, 'Well, I'm putting it on my body. There must be some sort of dermal transmission,'' Pollack said. Research on this is still ongoing, with a number of universities Like Duke researching whether PFAS can be absorbed through the skin. Last year, a team of researchers at Environment International, a team of researchers released findings that PFAS can indeed permeate the skin's barrier and enter the bloodstream.
'There are a number of states that have started to regulate PFAS in apparel and textiles more broadly, and each of the states defines those subjects differently,' Pollack said. In Washington state, for example, intentionally added PFAS—which is added to a product to attain a technical effect, like waterproofing—is banned. But other states, like Vermont, have an expanded ban that covers all PFAS detectable within a product, even if it's unintentionally added as a result of a manufacturing process.
Manufacturing is becoming an increasingly studied part of the PFAS journey, as the chemicals might be used on machines as a lubricant or a surfactant to help a plastic mold release, for example.
According to Pollack, regulation may have outpaced science at this juncture, with a less-than-complete understanding of PFAS' risks or methods of transmission into the human body. Most believe that drinking water is the primary route of exposure, though there are studies about whether it might be inhaled as dust particles, for example. As such, clothing and products like carpets (which might release those particles) are being studied.
In California, key regulations include bans on intentionally added PFAS chemicals in textiles, cosmetics and food packaging. The rollout of the PFAS textile ban will come in waves, as stipulated by AB1817. On Jan. 1, total organic fluorine levels were limited to 100 ppm, and that number will drop to 50 ppm in 2027 (though apparel made for severe outdoor conditions has until 2028 to achieve compliance).
Meanwhile, Maine, Minnesota and New Mexico have also made aggressive moves to ban the use of PFAS, with the former being the first to implement a comprehensive ban on all non-essential uses (though it's considering a bill that would exempt fluoropolymer-coated cookware). Minnesota and New Mexico also have broad bans on intentionally added use of PFAS, though Minnesota is mulling exempting commercial and industrial products. The state is also implementing mandatory chemical reporting requirements for products currently offered for sale on store shelves on Jan. 1, 2026.
'Those states are implementing these broad bans, and they create limited exemptions for what are called currently 'unavoidable uses,' which you have to apply for,' Pollack said. 'You have to show that there's no viable alternative and that the use is helpful for… the functioning of society or health and wellness of people. So a relatively limited exemption possibility there.'
Isabel Carey, a senior associate with the firm who heads up its Toronto office, spoke to Canada's regulatory environment.
'In March, Environment Canada and Health Canada proposed adding PFAS chemicals as a class with a major note as toxic substances under the Canadian Environmental Protection Act,' she explained, noting that fluoropolymers—a major type of PFAS used in the textile and apparel industry—are excluded because of differences in how people are exposed to them and the hazards that they pose to human health.
Once the government's proposal to classify the chemicals as toxic substances is finalized, there's no immediate regulatory consequence, nor does the classification prohibit the use of PFAS in the Canadian economy. It simply authorizes the government to issue regulations targeting those substances.
According to Marten Law, the agencies further proposed phasing out PFAS use 'wherever feasible'—firstly, in firefighting foams, and then across a range of industries like textiles, food packaging, cosmetics and medical devices where they believe the chemicals can be replaced. During Phase Two of regulation, Canada will evaluate prohibiting PFAS use in industries where alternatives are not available, and where the chemicals aren't being used for the protection of human health, safety or the environment.
The agencies haven't proposed binding regulations to implement their plans, but have announced that implementing regulations will be developed beginning in 2027, Marten Law added.
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Yahoo
15 hours ago
- Yahoo
The Best Foods to Eat to Fight Inflammation, According to Dietitians
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This persistent inflammation has been linked to serious diseases like cancer, heart disease, arthritis, and diabetes. Fortunately, adopting a healthy diet and lifestyle can help combat chronic inflammation and lower disease risk. "Lowering inflammation in the body means eating a plant-forward diet and avoiding highly processed foods that contain trans fats or a lot of added sugar," says Pamela Fergusson, RD, Ph.D. Foods rich in antioxidants, like those featured in the Mediterranean diet, have been shown to effectively reduce inflammation. Beyond diet, maintaining seven to eight hours of sleep per night, staying active and managing stress are also crucial in fighting inflammation and improving overall health. Add more of the following healthy inflammation-fighting foods to your daily diet to see the benefits. Tart cherries pack a wallop of antioxidants that help temper inflammation, including anthocyanins (an antioxidant found in red and purple fruits and vegetables) and vitamin C (well-known for its immune-supporting properties). Data shows that tart cherries contain beneficial compounds called polyphenols, which have antioxidant and anti-inflammatory effects. These compounds may help by targeting the processes in the body that cause or worsen inflammation. Research shows that tart cherries could help lower markers of inflammation and reduce the risk of chronic diseases. The active ingredients in tart cherries, such as cyanidins, quercetin and melatonin, are thought to play a key role in may be attributed to the impact of the active compounds in tart cherries on inflammatory pathways, including NF-κB and mitogen-activated protein kinase. Incorporate more cherries into your diet with smoothies, as a yogurt or oatmeal topper, in sorbet or simply on their own for an easy, naturally sweet snack. Packed with healthy monounsaturated fatty acids that help to keep our hearts happy, avocados are also an excellent source of fiber. "One of the simplest things you can do to eat in an anti-inflammatory way and prevent disease is to eat a diet high in fiber," says Fergusson. For one, fiber makes maintaining a healthy weight easier, which in turn helps ward off weight-related inflammation. Additionally, fiber is what keeps our gut microbiome happy and healthy, which we now know plays a critical role in chronic disease development. Just like cherries contain anthocyanins, beets contain different phytochemicals—called betalains—that act similarly in the body to fight off inflammation. They're also a heartier vegetable that can be store for longer without going bad, which is an added bonus if you're trying to reduce food waste. Whether you add beets to your juicer or roast them as a salad topper, you'll get a healthy dose of helpful nutrients. Eating salmon or other fatty fish, like sardines and mackerel, at least twice a week delivers an impressive amount of healthy omega-3 fatty acids, which have been found to 'turn off' pro-inflammatory genes in your body and increase cells' ability to scrub themselves of harmful components. Not feeling fish? Eat 1 to 2 tablespoons of chia seeds, ground flaxseed or walnuts to get plant-based omega-3 fats. From almonds to cashews, pistachios and walnuts, you can choose your favorite (or mix it up) when designing an anti-inflammatory diet. Eating nuts, such as almonds and walnuts, may help lower inflammation, while Brazil nuts might reduce oxidative stress because of their antioxidant properties. 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Chronic inflammation is a serious health concern, but the good news is that taking proactive steps through diet and lifestyle may make a significant difference. By incorporating nutrient-rich, anti-inflammatory foods such as tart cherries, avocados, fatty fish, nuts and dark leafy greens into your meals, you can help your body combat inflammation naturally. These foods are not only delicious but also loaded with nutrients that work together to reduce inflammation, support your immune system, and promote overall well-being. A balanced approach to eating, along with staying active, prioritizing sleep, and managing stress, is key for combatting the harmful effects of chronic inflammation. Ultimately, small, consistent changes hold the power to protect your health and enhance your quality of life. Whether it's adding beets to your salad, seasoning your dishes with inflammation-fighting spices, or swapping out fried snacks for nuts, every choice counts. 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Business Upturn
18 hours ago
- Business Upturn
Ferring ADAPT-1 Trial Builds on Dosing Evidence for Follitropin Delta
Business Wire India Follitropin delta starting dose of 15 micrograms (µg)/day has comparable efficacy and safety as a starting dose of 225 International Units (IU)/day of follitropin alfa for ovarian stimulation in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) gonadotrophin-releasing hormone (GnRH) antagonist protocol cycles. This is the key finding of a trial presented today at the European Society of Human Reproduction and Embryology (ESHRE) Congress in Paris and published in Human Reproduction. These data build on previous studies which have established an estimated point of clinical correspondence for 10 µg follitropin delta to 150 IU follitropin alfa in this class of medications.1,2 The ADAPT-1 trial was a multicentre, randomised, assessor-blind study involving 300 women aged 18-40 years undergoing IVF or ICSI.3 The trial compared the efficacy and safety of follitropin delta and follitropin alfa using conventional dosing regimens with a primary endpoint of number of oocytes retrieved. Currently, follitropin delta is approved for use via a dosing algorithm based on serum anti-Müllerian Hormone (AMH) and bodyweight individualised for each patient, and aims to obtain an ovarian response which is associated with a favourable safety/efficacy profile. The clinical value of this approach has been well established4,5,6,7,8, particularly in treatment-naïve patients where the algorithm aims to achieve 8–14 retrieved oocytes while minimising the risk of ovarian hyperstimulation syndrome (OHSS) to optimise the live birth rate in a fresh and frozen transfer cycle.4,5,6,7,8 Key Findings: Ovarian Response: Both treatment groups achieved a mean of 9.9 oocytes retrieved, indicating similar efficacy Both treatment groups achieved a mean of 9.9 oocytes retrieved, indicating similar efficacy Clinical Pregnancy Rates: Clinical pregnancy rates were similar for follitropin delta 31.6% versus 31.0% for follitropin alfa Clinical pregnancy rates were similar for follitropin delta 31.6% versus 31.0% for follitropin alfa Drug Product Usage: After measurement unit conversion, the mean total dose patients were exposed to was numerically lower for follitropin delta (143.7±33.6 µg) than follitropin alfa (154.3±23.1 µg or 2,105±315 IU) After measurement unit conversion, the mean total dose patients were exposed to was numerically lower for follitropin delta (143.7±33.6 µg) than follitropin alfa (154.3±23.1 µg or 2,105±315 IU) OHSS Rates: Early OHSS rates were low (2.5% for follitropin delta and 3.0% for follitropin alfa), with no cycle cancellations due to excessive ovarian response on either arm of the study. Dr Andrea Bernabeu, Medical Director at Instituto Bernabeu and principal investigator of the ADAPT-1 trial, said: "No patients we see as fertility doctors are the same and the ability to optimise therapy based on patients age, treatment goal and whether they have a high or low response to follicular stimulation are all relevant. These data provide confidence and expand our understanding for dosing in follitropin delta." Pierre-Yves Berclaz, Chief Science and Medical Officer at Ferring Pharmaceuticals, stated: "The ADAPT-1 trial results confirm the efficacy and safety of follitropin delta across the full range of dosing strategies, making it the only recombinant FSH with robust clinical evidence supporting multiple dosing strategies. Ferring will take forward the implications of this study in future dialogue with regulatory authorities." About GnRH protocols Gonadotrophin-releasing hormone (GnRH) agonists and antagonists are used as concomitant treatment during ovarian stimulation to prevent premature luteinisation and ovulation for IVF/ICSI.7,8 About Follitropin Delta (Rekovelle®) Follitropin delta is a human cell line-derived rFSH with an approved dosing algorithm designed for a predictable ovarian response.3 It is the first rFSH derived from a human cell line (PER.C6® cell line). Follitropin delta is structurally and biochemically distinct from other existing rFSH gonadotrophins.3,4 Follitropin delta is approved in certain markets for use in controlled ovarian stimulation for the development of multiple follicles in women undergoing assisted reproductive technologies (ART), such as IVF or ICSI cycle. The individualised dosing of follitropin delta is determined using an approved algorithm, based on a woman's AMH level and body weight.3,5 AMH is a biomarker used to assess ovarian reserve and can help predict ovarian response.5,6 The follitropin delta dose should be based on AMH level, measured using the ELECSYS AMH Plus immunoassay from Roche, the ACCESS AMH Advanced from Beckman Coulter, or LUMIPULSE G AMH from Fujirebio.3 About Ferring Pharmaceuticals Ferring Pharmaceuticals is a privately owned, research-driven, specialty biopharmaceutical group committed to building families and helping people live better lives. We are leaders in reproductive medicine with a strong heritage in areas of gastroenterology and urology, and are at the forefront of innovation in uro-oncology gene therapy. Ferring was founded in 1950 and employs more than 7,000 people worldwide. The company is headquartered in Saint-Prex, Switzerland, and has operating subsidiaries in more than 50 countries which market its medicines in over 100 countries. Learn more at or connect with us on LinkedIn, Instagram, YouTube, Facebook and X. REFERENCES 1 – Arce JC, Larsson P, Garcia-Velasco JA; Establishing the follitropin delta dose that provides a comparable ovarian response to 150 IU/day follitropin alfa; RBMO; 2020 2 – Yang R, Zhang Y, Liang X et al; Comparative clinical outcome following individualized follitropin delta dosing in Chinese women undergoing ovarian stimulation for in vitro fertilization / intracytoplasmic sperm injection; Reproductive Biology and Endocrinology; 2022 3 – Clinical page: (Accessed June 2025) 4 – Andersen, A. N., Nelson, S. M., Fauser, B. et al. (2017). Individualized versus conventional ovarian stimulation for in vitro fertilization: A multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial. Fertility and Sterility, 107(2), 387-396. 5 – Bosch E, Havelock J, Martin FS, Rasmussen BB, Klein BM, Mannaerts B, Arce JC; ESTHER-2 Study Group. Follitropin delta in repeated ovarian stimulation for IVF: a controlled, assessor-blind Phase 3 safety trial. Reprod Biomed Online. 2019 Feb;38(2):195-205. PMID: 30594482. 6 – Ishihara O, Arce JC, Japanese Follitropin Delta Phase 3 Trial G. Individualized follitropin delta dosing reduces OHSS risk in Japanese IVF/ICSI patients: a randomized controlled trial. Reprod Biomed Online. 2021 May;42(5):909-18. PubMed PMID: 33722477. Epub 2021/03/17. 7 – Qiao J, Zhang Y, Liang X, et al. A randomised controlled trial to clinically validate follitropin delta in its individualised dosing regimen for ovarian stimulation in Asian IVF/ICSI patients. Hum Reprod. 2021 Jun 28;36(9):2452-62. PubMed PMID: 34179971. Epub 2021/06/29. 8 – Blockeel C, Griesinger G, Rago R, et al. Prospective multicenter non-interventional real-world study to assess the patterns of use, effectiveness and safety of follitropin delta in routine clinical practice (the PROFILE study). Frontiers in Endocrinology. 2022 Dec 22;13:992677. PMID: 36619578. View source version on Disclaimer: The above press release comes to you under an arrangement with Business Wire India. Business Upturn take no editorial responsibility for the same. Ahmedabad Plane Crash
Yahoo
18 hours ago
- Yahoo
7 Common Phrases That Drive Anti-Diet Dietitians Nuts
When you think of a nutritionist or dietitian, you probably think of someone who scolds you into following a certain meal plan and maybe even tells you to avoid some foods altogether. While that certainly can happen, there are a new swath of dietitians following a set of inclusive nutrition guidelines that reject diet culture. These folks, known as anti-diet dietitians and nutritionists, 'help people build a healthy relationship with food, their body and health — without the pressure to shrink themselves,' Dalina Soto, a registered dietitian and founder of Your Latina Nutritionist, told HuffPost. You also won't find rigid food rules or meal plans, Soto said. Exactly how an anti-diet dietitian practices varies depending on their training and preference, but it may mean they focus on intuitive eating or help you unlearn the diet-culture-coded thought patterns you have. Thoughts like, 'eating a whole bagel is bad,' for example. Anti-diet dietitians still help people achieve goals like managing diabetes or lowering blood pressure, just in a way that doesn't employ shame as the motivator. Instead, they celebrate bodies of all shapes and sizes that have always existed and will always exist, said Abby Chan, a registered dietitian and co-owner of Evolve Flagstaff in Arizona. Anti-diet dietitians also look at health holistically. 'When we look at someone's health, that doesn't just mean physical health. It means emotional health and mental health, community health and all these other ways that we're relating to the world around us,' Chan added. Diet culture, with its strict rules and shame-ridden meal plans, makes it hard to have prime mental and emotional health. And, unfortunately, it's just as hard to turn off the noise of diet culture in a world that is heavily influenced by it. Experts say there are certain common thoughts and phrases that celebrate diet culture (and make folks feel bad). Here's what some of those phrases are: Calling any foods or drinks 'bad' is a diet culture red flag, said Sam Previte, a registered dietitian and the founder of Find Food Freedom. And that's true whether you're referring to a certain food, ingredient or even yourself after eating something. 'That's applying morality to food, and it's so important to recognize that removing morality from food, meaning calling it good or bad, can help make peace with it,' said Previte. Sometimes, people think they can just eat 'healthy food' and rid their lives of any guilt or shame that could come from eating these more fun foods, Previte noted. 'Sure, you could try that for a little bit, but diets are unsustainable, you're going to eat these fun foods like cake and pizza, and they should be enjoyed,' she said. 'There is no meal plan in the world that is going to be able to remove guilt and shame from your eating experiences if you're feeling those, and that's where this intuitive eating, anti-diet work comes in,' Previte said. Nutrient-dense foods play an important role in your meal plan, but so do 'these fun, indulgent foods that taste so good and are so much more than just fuel. They're tradition, they're culture, they're emotions, they're comfort. They're so many things,' she said. 'Clean eating' is all over social media and even on the shelves of certain grocery stores, but it's a term that anti-diet dietitians take issue with. 'How do we define 'clean'? One, we don't even have the definition for what ultra-processed food is right now that anyone can agree on, and so how do we define 'clean'?' said Chan. 'Is it that you wash your food or you wash your hands before eating? If so, that's great, but I think ... it's rooted from this place of chemophobia,' which is a fear or prejudice against chemicals. And, it's worth noting that everything is made up of chemicals, even those pieces of fruit which are often referred to as a 'clean' food. 'It's only when there is a nutrition label with 'scary' ingredients listed do people think that they're about to eat something 'bad,'' Chan added. (Which, of course, isn't true.) 'The clean eating really, really bothers me because also, on the flip side of that, if you're not eating 'clean,' then what does that mean? That means that you're eating dirty, and nobody wants to be 'dirty,'' Chan added. 'I often see people talking about empty calories, and that's just a false narrative,' Previte said. 'I cringe at my younger self. I often talk about how I was taught to be more of a diet culture dietitian, as most dietitians are classically trained in restricting people, and so I remember using that rhetoric of 'Well, that's an empty calorie because it doesn't provide a lot of nutrient density,'' said Previte. While certain foods do provide different vitamins and minerals, all calories provide our body with energy, Previte noted. 'So, there's no such thing as an empty calorie. You'll find a lot of people use that terminology for a donut, or some type of carb-rich food, usually,' she said. If you were stranded on an island and only had donuts to eat, it would be nutritious, delicious and keep you alive by supplying your body with calories, Previte said. Meaning, there is nothing 'empty' about those calories. Cheat meals and cheat days are synonymous with workout and diet culture. For example, someone who's trying to hit a certain weight may refer to the weekend as their 'cheat days' or may refer to a lunch out with friends as a 'cheat meal.' But using the phrase 'cheat meals' once again brings morality into food, Previte said. 'If we believe that all food is neutral, or if we believe that all foods fit, there's no such thing as cheating, because it's just food,' added Previte. Processed foods are forever vilified by wellness influencers who call these products 'bad' and link them to health issues, but processed foods are simply items that are altered from their original state in any way, whether that's by washing, mixing, cooking or freezing. 'I don't eat processed foods ... what does that mean? You don't cut your carrots and you don't wash them? Because technically, that's processing them,' said Chan. When people hear the phrase 'processed foods,' they think of items that aren't nutrient-dense and 'shouldn't' be part of their meal plan, but this couldn't be further from the truth. 'A lot of these foods are just accessible, whether it be from an ability standpoint, some people may not be able to chop and cut all of their fruits and vegetables,' Chan said. Or maybe someone doesn't want their fresh veggies to go bad so they opt for frozen or canned alternatives, she added. If you wander down the supplement aisle at the grocery store, you'll likely see products that promise a 'cleanse' or 'detox,' whether that's a juice, tea, powdered concoction or pill. These items fuel the idea that detoxes are necessary, when they actually really aren't (and products can't detox you). 'Anytime I see those words [detox or cleanse], it's just automatic eye roll,' Previte said. 'We have organs that exist in our body that cleanse us of things that we don't need,' she explained. 'If we have access to clean water, water helps flush out our bodies,' Previte added. No green powder or tea is going to detox or cleanse you. Instead, your organs and body will handle that. 'I love to explain to people, the only detox you should be doing is a social media detox of the wellness influencers and bullshit con artists that are making you feel bad about your food choices and your body,' Previte said. You may have heard (or used) the phrase 'calories don't count,' particularly on vacation, during the holidays or over the weekend, said Kathleen Meehan, a registered dietitian. Maybe you've used it as an 'excuse' when sipping a fruity cocktail on vacation or while eating your mom's baked pies on Thanksgiving. This is a phrase that's often thrown around without much thought, but it's one that drives Meehan up the wall. 'Calories absolutely 'count,' and thank goodness they do. Calories are units of energy,' Meehan said. 'They provide our bodies with energy,' she added. Instead of telling yourself that calories don't count in order to eat something you like, 'I encourage clients to reconsider 'low calorie' as 'low energy,'' said Meehan. 'Suddenly that low-calorie meal doesn't sound so helpful,' she noted. Diet culture is deeply rooted into nearly everything we do. You likely won't be able to just stop thinking of certain foods as 'bad' or referring to certain meal plans as 'eating clean' at the drop of a hat. Instead, it'll take some work. There are anti-diet dietitians, many of whom take insurance, who can specifically help you, but overall, there are a few things you can do to fight back against these intrusive diet culture thoughts. 'The first step is awareness — just naming when a thought is rooted in diet culture can be powerful,' said Soto. Instead of judging yourself for having these thoughts, get curious, Soto said. 'Ask yourself, 'Where did I learn this?' or 'Who benefits when I feel bad about my body?'' Soto added. 'Then, we work on reframing. That might sound like 'all foods fit,' or 'I'm allowed to enjoy food without earning it,'' she said. It's also important to surround yourself with weight-neutral voices, to set boundaries in conversations that trigger you and reconnect with your body's food signals, Soto said. If you do find yourself saying any of these diet-culture-coded phrases, Previte said you shouldn't feel ashamed. Diet culture is a beast to fight back against as this rhetoric comes from generations of food habits and a media landscape that celebrates thin bodies. 'You're going to be inundated with all of these messages,' Chan added. But, 'just because something's normalized doesn't mean it's normal,' Chan said. Society has made it normal to associate certain foods with guilt or bad feelings, but that doesn't have to be the case. Your food choices don't have to come with guilt or shame, and instead can be an opportunity for you to nourish your body with the nutrients and joy it needs. If you're struggling with an eating disorder, call or text 988 or chat for support. 6 Common Phrases You May Not Realize Are Actually Fat-Shaming Have You Been Cooking With Your Pans For Too Long? Here's How To Tell Nutritionists Are So Worried You Aren't Getting These 4 Nutrients, They're Calling It A 'Public Health Concern'