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Bristol Myers' drug fails to meet main goal of late-stage anemia trial

Bristol Myers' drug fails to meet main goal of late-stage anemia trial

Reuters18-07-2025
July 18 (Reuters) - Bristol Myers Squibb (BMY.N), opens new tab said on Friday its drug Reblozyl in combination with another therapy failed to meet the main goal of a late-stage trial to treat anemia due to a rare bone marrow cancer.
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What are heat streaks? The extreme weather phenomenon on the rise
What are heat streaks? The extreme weather phenomenon on the rise

The Independent

time30 minutes ago

  • The Independent

What are heat streaks? The extreme weather phenomenon on the rise

If it feels like this hot summer is never ending, that's because life-threatening heat waves are becoming stronger and lasting longer due to the effects of human-caused climate change. Heat streaks, or the number of consecutive hot days, are also on the rise across U.S. cities, according to the non-profit Climate Central. Of the 247 cities the group analyzed, the number of extreme heat streaks has increased by 80 percent. 'When extreme heat lingers for days during heat waves, or heat streaks, the risk of heat-related illness rises — particularly for children, pregnant people, and weather-exposed workers among others,' Climate Central said. The report examined the changing frequency of extreme heat streaks in those cities ​​from 1970 to 2024. On average, it found that the 198 cities experience two more extreme heat streaks a year than in the early 1970s. Cities in the Southwest, Northeast, Ohio Valley, and Southeast saw the largest increase in frequency. Tennessee's capital of Nashville, North Carolina's capital of Raleigh, Wheeling, West Virginia, and Wilkes Barre, Pennsylvania, all now see five more streaks than in the early 1970s. The consequences of these extreme weather events can be severe. They can worsen air quality, potentially sending people with respiratory illness to the hospital. They can also strain the electrical grid and lead to power outages that expose people to the dangerous heat. Heat is the leading cause of weather-related deaths in the U.S., with a record 2,325 heat deaths recorded i n 2023. Friday marks the beginning of another dangerous and oppressive heat wave for 100 million Americans. The heat dome will bring temperatures between five and 15 degrees Fahrenheit above the historical average, with temperatures of 95 degrees or even higher, according to AccuWeather. In New York, where the 'feels like' temperature on Friday was expected to hit 105 degrees, residents will also have to deal with high humidity, severe thunderstorms, and damaging wind gusts of up to 58 miles per hour. Humidity can make hotter temperatures feel even worse, resulting in a faster heartbeat and other negative health effects. "The combination of extreme temperatures, high humidity and light winds will likely send afternoon AccuWeather RealFeel Temperatures to between 110 and 115 [degrees Fahrenheit] from the states that touch the western part of the Gulf through Oklahoma and Arkansas, as well as portions of Missouri, Illinois, Indiana and Tennessee," AccuWeather Senior Meteorologist Brett Anderson said. "At this level, it can be dangerous for many people who are exposed to the heat for an extended period of time, leading to heat-related illnesses that can sneak up on some individuals,' he noted. The heat is expected to linger into early next week, as the dome expands over the Central U.S. and Southeast states.

Popular restaurant unknowingly drugs customers by serving them marijuana pizza, CDC report claims
Popular restaurant unknowingly drugs customers by serving them marijuana pizza, CDC report claims

Daily Mail​

time31 minutes ago

  • Daily Mail​

Popular restaurant unknowingly drugs customers by serving them marijuana pizza, CDC report claims

Health officials have revealed that a Wisconsin restaurant accidentally laced its pizzas with drugs, leading to the intoxication of 85 customers. Famous Yeti's Pizza in Stoughton, Wisconsin, unintentionally served pizzas contaminated with THC, the psychoactive compound in marijuana, between October 22 and October 24, 2024. In a new CDC report, EMS workers reportedly notified the public health department that they transported seven people to the hospital with THC intoxication-related symptoms, including dizziness, anxiety, paranoia and hallucinations over the course of the two days. All of the patients reported eating at Famous Yeti's, and one patient said they felt similar to when they took a THC edible. He and the other patients, ranging from ages 1 to 91, later tested positive for the drug, the public health department reported. An investigation determined that on October 22, the restaurant had run out of cooking oil and used oil from a shared cooperative kitchen located in the same building. One of the vendors who used the kitchen made edible products using that cooking oil, which contained hemp-derived THC. Hemp-derived THC can cause a range of side effects including intoxication, altered senses, impaired thinking and coordination, anxiety, and in some cases, more severe reactions like hallucinations or paranoia. In addition to the seven people taken to hospital, 78 others who dined at the restaurant revealed in a health questionnaire that they had at least one symptom of THC intoxication within five hours after dining there. Some of the complaints claimed they suffered from dizziness, sleepiness, anxiety, increased heart rate, nausea, paranoia, panic attack, increased blood pressure, vomiting, and hallucinations. All 85 people who were identified made full recoveries without any complications. The only label warning that the borrowed cooking oil contained THC was on the cap, which the operator reportedly saw, according to the health department. Famous Yeti's later addressed the issue by posting a public notice on its Facebook page. Its owner Cale Ryan wrote at the time: 'In the past few days, we at Famous Yeti's Pizza made a horrendous mistake and in doing so, compromised the trust we have spent 12 and a half years building with this amazing town. 'We put people and families at risk and frightened and confused children and parents. 'This is incredibly serious to us and we can't imagine anything worse than betraying the faith that our customers have in us to provide a product made with [the] utmost care and without concern. 'We acted with carelessness in prepping dough and ended up tainting our product that we take so much pride in.' Ryan went on to say that as the owner he took 'full responsibility for this oversight.' He added: 'I am incredibly sorry that I allowed us to act this irresponsibly and ended up hurting the people who have made Yeti's the wonderful place it has been. 'All I can ask from here is your forgiveness and your faith that he will do everything within our power to earn that trust and love back. Still, he said: 'If we lost your faith in us and we never get to serve you again, I completely understand. 'We made a tremendous error and know that we will always be here with an open ear and an open heart, and we will work furiously to earn this privilege to provide for your sometime again.' A police investigation concluded that the provision of THC-contaminated food to customers was unintentional, and no criminal charges were pursued. The restaurant reopened on October 26 after cleaning and sanitizing following standards in the Wisconsin Food Code. More than six months on, the restaurant is still in business and it remains a popular local eatery. Following the incident, the CDC warns restaurants that clear labeling and locked storage for ingredients containing THC is essential in ensuring customer safety.

EU regulator backs Moderna's updated COVID vaccine
EU regulator backs Moderna's updated COVID vaccine

Reuters

time31 minutes ago

  • Reuters

EU regulator backs Moderna's updated COVID vaccine

July 25 (Reuters) - The European Union's drug regulator has recommended approval of Moderna's (MRNA.O), opens new tab updated formulation of COVID-19 shot Spikevax, the vaccine maker said on Friday. The updated shot targets the LP.8.1 variant, part of the JN.1 lineage, to prevent COVID-19 in individuals six months of age and older, Moderna said. It expects to make the mRNA-based shot available for the 2025-26 vaccination season, pending a European Commission approval. Any recommendation by the European Medicines Agency's human medicines committee has to be formally approved by the EC, which usually follows the regulator's decision. Moderna had filed a marketing application for the review of its updated vaccine with the U.S. Food and Drug Administration in May.

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