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Scientists pinpoint diet tweak that can help people lose 1lb a week without counting calories

Scientists pinpoint diet tweak that can help people lose 1lb a week without counting calories

Daily Mail​2 days ago

Ditching meat for a just a few months could help you lose almost a pound a week, shock new research has suggested.
US scientists found that overweight adults who went vegan for roughly four months were just over 13lbs (6kg) lighter by the end of the study.
They credited the slimming effect to plant-based diets—those devoid of meat, dairy and eggs—producing less acid during digestion.
Researchers said the higher levels 'dietary acid' produced by animal products increased inflammation in the body.
This in turn disrupts the delicate internal processes in the body— like the metabolism and hormone production—contributing to weight gain, they explained.
Dr Hana Kahleova, an expert in nutrition from the Physicians Committee for Responsible Medicine in Washington and lead author of the new study, claimed the findings show the benefits of embracing veganism.
'Replacing animal products with plant-based foods like leafy greens, berries, and legumes can help promote weight loss and create a healthy gut microbiome,' she said.
In the study, 62 overweight adults were put on either a vegan-diet or the health-focused Mediterranean diet for 16 weeks.
The latter emphasises eating fresh vegetables, healthy fats such as those from olive oil and nuts and lean meats like fish and chicken.
Participants' body weight was measured before and after the diet.
Then—after a four week break—the group did another 16 weeks on the other diet.
This allowed researchers to compare weight loss across the two diets using the same participants.
Scientists also compared the 'dietary acid' scores of the foods the participants consumed across the two diets.
At the study's conclusion, the vegan diet saw participants lose an average of 13.2 lbs (6kg) in 16 weeks, roughly 13oz (375g) per week.
By contrast, those on the Mediterranean diet didn't experience any significant weight loss, the authors said.
Writing in the journal the Frontiers in Nutrition, they recommended dieters looking to slim down to incorporate more fruit, vegetables and grains that counteract dietary acid— a process called alkalising—into their diet.
The team specifically highlighted vegetables like leafy greens, broccoli, beets, asparagus, garlic, carrots, and cabbage.
For fruits, they recommended berries, apples, cherries, apricots, or melons.
Researchers also said legumes like lentils, chickpeas, peas, beans, soy products such as tofu and alternative grains like quinoa or millet could also have this effect.
While Britons have been told for years to up their intake of fresh fruit and vegetables and cut down of fatty cuts and processed meats for their health, there are some health hazards to going completely vegan.
Nutritionists have previously warned that vegans can miss out on a range of key vitamins and minerals by shunning animal products.
These include a lack of vitamin B12, which is in found milk and eggs, which can lead to fatigue or tiredness and negatively impact mental health.
Vitamin D is another nutrient found mainly in animal products, like oily fish, that those on vegan diets can be deficient in.
A vitamin D deficiency can lead to issues with bone development and cause pain.
A lack of iron, found in red meat and liver, can also lead to anaemia, causing people to feel tired and have heart palpitations.
Iodine, mainly found in seafood, is another nutrient known to be lacking in vegan diets and is important in maintaining a health metabolism.
While plant-based diets can include all of these mentioned nutrients, vegans need to carefully manage what they eat, or take supplements, to ensure they get enough.
There have also been concerns about the potential health impacts of fake 'meats' in vegan diets.
Last year, British experts found those who ate plant-based versions of sausages, burgers and mince seemingly had worse blood pressure than their meat-consuming counterparts
Another recent UK study revealed that opting for ultra-processed plant foods, like vegan sausages and burgers, as well as cakes and crisps, was linked to a 15 per cent higher risk of suffering heart attacks and strokes.
Interest in a plant-based diet has soared in recent years, with vegans citing ethical, environmental or health reasons.
The exact numbers of vegans now in the UK is almost impossible to establish.
But one recent survey suggested around 600,000 people are believed to be on a plant-based diet.
In England, one in four adults are now obese, while just over three in five are overweight.
However, four out of five adults are either overweight or obese in some areas of the country.
The NHS recommends that those overweight wanting to lose weight focus on consuming fewer calories overall and eating more healthily while upping the amount of weekly exercise.
The health service cautions that using what it dubs 'fad diets' may lead to short term weight loss this is rarely sustainable.

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How dem make anti-venom from man wey snake bite 200 times
How dem make anti-venom from man wey snake bite 200 times

BBC News

time27 minutes ago

  • BBC News

How dem make anti-venom from man wey snake bite 200 times

Di blood of one US man wey deliberately inject imsef wit snake venom for nearly twenty years don lead to "unparalleled" anti-venom, scientists tok. Antibodies find in Tim Friede blood don shown to protect against deadly doses from one wide range of species in animal tests. Current therapies gatz match di specific species of venomous snake wey bite anyone. But Oga Friede 18-year mission fit lead to ogbonge step of finding universal anti-venom against all snakebites - wey dey kill up to 140,000 pipo evri year and leave three times as many needing amputations or facing permanent disability. In total, Mr Friede don endure more dan 200 bites and more dan 700 injections of venom e prepare from some of di world deadliest snakes, including multiple species of mambas, cobras, taipans and kraits. E bin want build up im immunity to protect imsef wen e dey handle snakes, documenting im exploits on YouTube. But di former truck mechanic tok say e don "completely screw up" early on wen two cobra bites wey happun in quick succession leave am in coma. "I no wan die. I no wan lose one finger. I no wan miss work," e tell BBC. Oga Friede motivation na to develop beta therapies for di rest of di world, explaining: "E just become lifestyle and I just keep pushing and pushing and pushing as hard as I fit push - for di pipo wey dey 8,000 miles away from me wey don die from snakebite". 'I go love to get my hands on some of your blood' Currently dem dey make anti-venom by injecting small doses of snake venom into animals, such as horses. Dia immune system dey fight di venom by producing antibodies and dem go harvest am to use as therapy. But venom and anti-venom gatz dey closely matched becos di toxins for venomous bite no be di same from one species to anoda. Dem even get wide variety within di same species – anti-venom wey dem make from snakes from India dey less effective against di same species for Sri Lanka. One team of researchers begin dey search for one type of immune defence wey dem dey call broadly neutralising antibodies. Instead of targeting di part of toxin wey make am unique, dem dey target di part wey make am common to entire classes of toxin. Dat na wen Dr Jacob Glanville, chief executive of biotech company Centivax, come across Tim Friede. "Immediately I look say 'if anybody in di world don develop dis broadly neutralising antibodies, e go be am' and so I reach out," e tok. "Di first call, I be like 'dis fit dey awkward, but I go love get my hands on some of your blood'." Oga Friede agree and di work dey ethically approved becos di study go only take blood, rather dan give am more venom. Di research focus on elapids – one of di two families of venomous snakes – such as coral snakes, mambas, cobras, taipans and kraits. Elapids primarily use neurotoxins in dia venom, wey dey paralyse dia victim and e dey fatal wen dem stop di muscles e need to breathe. Researchers don pick 19 elapids identify by di World Health Organization as being among di deadliest snakes on di planet. Dem don begin to source for Oga Friede blood for protective defences. Dia work, dey detailed in di journal Cell, identify two broadly neutralising antibodies wey fit target two classes of neurotoxin. For experiments on mice, di cocktail mean say di animals bin survive deadly doses from 13 of di 19 species of venomous snake. Dem bin get partial protection against di remaining six. Dis na "unparalleled" breadth of protection, according to Dr Glanville, wey say e "likely cover a whole bunch of elapids for wey no get current anti-venom". Di team dey try to refine di antibodies further and see if adding fourth component fit lead to total protection against elapid snake venom. Di oda class of snake – di vipers – dey rely more on haemotoxins, wey dey attack di blood, rather dan neurotoxins. In total around one dozen broad classes of toxin in snake venom, wey also include cytotoxins dey directly kill cells. "I think in di next 10 or 15 years we go get somtin effective against each one of dis toxin classes," Prof Peter Kwong, one of di researchers for Columbia University, tok. And di hunt continue inside Oga Friede blood samples. "Tim antibodies dey really quite extraordinary - e bin teach im immune system to get dis veri, veri broad recognition," Prof Kwong tok. Di ultimate hope na to get either single anti-venom wey fit do evritin, or one injection for elapids and one for vipers. Prof Nick Casewell, na di head of di centre for snakebite research and interventions for di Liverpool School of Tropical Medicine - e tok say di breadth of protection report bin dey unusual and provide "strong piece of evidence" wey get feasible approach. "No doubt say dis work move di field forward in exciting direction." But e caution say "plenti work still dey to do" and di anti-venom still go need extensive testing bifor dem fit use am in pipo. But for Oga Friede, reaching dis stage "make me feel good". "I dey do somtin good for humanity and e bin dey veri important to me. I dey proud of am. E dey pretty cool."

Woman kept on life support for months due to pregnancy finally laid to rest
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Adriana Smith, an Atlanta mother and nurse, has finally been laid to rest, months after she was declared brain-dead after suffering a catastrophic stroke while eight weeks pregnant. The 31-year-old was kept on life support due to Georgia 's anti-abortion law, which grants personhood rights to a fetus, until her son, Chance, was delivered prematurely by emergency C-section. Smith's life support was turned off in mid-June and her funeral was held at Fairfield Baptist Church, just outside Atlanta, on Saturday. Her case has become a focal point for discussions on the impact of state-level abortion bans in medical emergencies and questions surrounding fetal personhood. Advocates and family members, including Democratic State Rep. Park Cannon, are pushing for 'Adriana's Law' to ensure individuals retain agency over their medical decisions, even while pregnant.

Look familiar? Scientists reveal what Neanderthals and Denisovans would look like TODAY if they hadn't gone extinct
Look familiar? Scientists reveal what Neanderthals and Denisovans would look like TODAY if they hadn't gone extinct

Daily Mail​

time3 hours ago

  • Daily Mail​

Look familiar? Scientists reveal what Neanderthals and Denisovans would look like TODAY if they hadn't gone extinct

For the last 40,000 years, Homo sapiens have been the only human species walking the Earth. Our ancient ancestors died out thousands of years ago, leaving behind nothing but fossils, a few scattered artefacts, and lingering traces in our DNA. But what if things had turned out differently? MailOnline has asked the experts to find out what the world might look like if the Neanderthals and Denisovans hadn't gone extinct. Surprisingly, they say that our distant evolutionary cousins might not be all that different to modern humans today. However, they might have had a hard time fitting in with our fast-paced, highly social societies. Dr April Noel, a palaeolithic archaeologist from the University of Victoria, told MailOnline: 'The idea that Neanderthals were hunched over, dim-witted individuals with no thought beyond their next meal is no longer tenable. 'At the same time, the idea that you could just slap a hat on a Neanderthal and you would not think twice about sitting next to him on the tube is also out the window.' What would they look like? Neanderthals and Denisovans are our closest ancient human relatives. The Neanderthals emerged around 400,000 years ago when they branched off from our common ancestors. Denisovans, meanwhile, are a far more elusive species of ancient humans who split from the Neanderthal evolutionary line around 430,000 years ago. If they had remained as separate species rather than going extinct, Neanderthals and Denisovans might look much the same as they did in the distant past. From the abundant fossil records, we know that Neanderthals were a little shorter than us on average, with shorter legs and wider hips. Neanderthals were very muscular and rugged, with large bodies and even larger heads. Their skulls show that they have room for a bigger brain than modern humans and would have been distinguished by a massive brow ridge and small foreheads. Neanderthals are our closest living relatives and share all our features to some degree. However, neanderthals have a stronger brow and a smaller forehead. Their skin tone would have depended on their climate, much like modern humans today (AI-generated impression) What would Neanderthals look like today? If Neanderthals survived until today, they might keep many of their original traits. This means they would be stockier and more heavily built than modern humans, with shorter legs and larger heads. Their faces would be distinguished by heavy brows and small foreheads. However, experts say that humans and Neanderthals would probably keep interbreeding. This means that these traits would become mixed with those of Homo sapiens. However, experts say they still would be clearly recognisable as fellow humans. Professor John Hawks, an anthropologist from the University of Wisconsin-Madison, told MailOnline: 'We don't know of any physiological traits that make Neanderthals distinct, that is, traits that don't overlap. 'Almost every physical trait in Neanderthals overlaps in its variation with ours today, at least to some extent.' That means they wouldn't look like lumbering cavemen or women, but rather like a slightly different variation of humans. Denisovans, meanwhile, are a little more of a mystery. It was only this month that scientists identified the first Denisovan skull, and besides this, there are only small fragments of bone to go on. Based on the newly identified skull, experts believe that Denisovans would have had a wide face with heavy, flat cheeks, a wide mouth, and a large nose. These bones also show that Denisovans would have been exceptionally large and muscular people, much stronger than more slender Homo sapiens. Not all that different However, experts say that Homo sapiens, Denisovans, and Neanderthals might not have remained that distinct for long. These human species interbred widely during the periods they overlapped, and many modern humans carry at least some Neanderthal and Denisovan DNA. If these species hadn't vanished, they might have continued to interbreed and further intermix our genes. Dr Hugo Zeberg, an expert on gene flow from Neanderthals and Denisovans into modern humans from the Karolinska Institutet in Sweden, told MailOnline: 'In a way they never went extinct. We merged!' 'Probably the relatively low amount of Neanderthal and Denisovan DNA in present humans reflects the fact that modern humans [Homo sapiens] were more numerous. 'But with more chances of encounters, we might have more archaic DNA present in the gene pool of modern humans.' We're still learning about how ancient genes influence modern humans, so it's hard to say what effects this mixing might produce. Neanderthals and modern humans interbred when we overlapped and would likely continue to into the future. Scientists say that male Neanderthal and Homo sapiens female couples would have had the highest likelihood of producing fertile hybrid offspring (AI-generated impression) Could modern and ancient populations merge? Scientists say it is extremely likely that Homo sapiens, Neanderthals, and Denisovans would eventually merge if no species went extinct. The resulting species would have genetic traits from all three groups. Since modern humans reproduce faster and build larger communities, they would likely represent more of the genetic material. This is essentially what happened to these species in the past. Our modern genome contains traits passed on from breeding with these ancient species before they disappeared. But Dr Zeberg points out that Denisovan genes are responsible for 'high altitude adaptation for Tibetans and some influence on lip shape in Latin American populations.' Similarly, Neanderthal and Homo Sapiens hybrids would likely have a mixture of the traits of both species such as larger heads, longer limbs, and narrower hips. Over time, some scientists believe Denisovans, Neanderthals and Homo Sapiens might have merged into a single human species with a mixture of all the traits. Dr Bence Viola, a paleoanthropologist at the University of Toronto, told MailOnline: 'I think it would have been impossible for Denisovans and Neanderthals to retain sufficient genetic isolation to remain a separate population. 'We know that they interbred with modern humans whenever they came into contact, and so the more contact there is, the more mixing happens – so they would have become a part of us.' Would they fit in? We don't currently know very much about how Denisovans lived, but research now shows Neanderthals might have struggled to fit in with modern society. One of the leading theories for why Homo sapiens survived while other species dropped off is that modern humans essentially 'tamed' ourselves. Unlike modern humans, Neanderthals and Denisovans didn't evolve to be so sociable. Scientists say they would find it difficult to integrate into our hyper-social society (AI-generated impression) Could Neanderthals and modern humans coexist? Scientists aren't sure whether Homo sapiens and Neanderthals could have cohabited permanently. There is no evidence of violence between the two species and we know that groups met and interbred frequently. However, Neanderthals are not as pro-social as modern humans and lived in much smaller groups. Homo sapiens also have a long history of violence and discrimination targeted against other human groups. In large, connected modern cities this could lead to conflict between the two species. Modern humans developed genes that allowed us to become more sociable, develop larger social networks, and work with our fellow humans. Dr Noel says: 'Unlike their modern human contemporaries, Neanderthals lived in small, fairly isolated groups. 'If there was an accident that killed a number of their hunters or some other crisis occurred, they did not always have others to reach out to. As a result, their numbers would drop below what you need to be sustainable.' Dr Noel points out that research into Neanderthal genes suggests they were less cognitively flexible, had greater difficulties processing language, and lacked genes related to self-awareness, creativity, and behaviours intended to benefit others. 'In the highly connected world we all live in, I think Neanderthals would have been left behind, or at least, left out,' says Dr Noel. In a world where Neanderthals lived alongside other human species, this could really change the way society was structured. Professor Spikins says that while modern humans became 'tamer, more playful and more friendly to each other,' those changes came alongside 'being a bit easily led'. She adds: 'If Neanderthals were better at not "following the herd" and more of those tendencies were present, I bet much of our world would be different; they might not be easily swayed by social media!' How would the world be different? If Neanderthals and Denisovans hadn't gone extinct thousands of years ago, the world might be a very different place. From the evidence we have of these ancient species, we know that they lived in much smaller communities and had a far more limited impact on the land. In fact, Dr Zeberg points out that modern humans appear to be unique in the way that we modify the world around us through agriculture and large cities. One strange consequence of this is that a world where Homo sapiens are not dominant might mean a world without pets. There is no evidence that Neanderthals and Denisovans attempted to nurture relationships with animals through domestication - that means no horses, cats, dogs or even modern agricultural species like cattle and sheep. But with more of our relative anti-social genes, humanity may also have avoided some of its more destructive tendencies. Professor Spikins says: 'If Neanderthals had been the ones to survive, we might not have the problem we have with climate change, as their tendency to be more isolated within their separate groups might have limited how technology spread and got used, and how much the environment got exploited.' THE DENISOVANS EXPLAINED Who were they? The Denisovans are an extinct species of human that appear to have lived in Siberia and even down as far as southeast Asia. The individuals belonged to a genetically distinct group of humans that were distantly related to Neanderthals but even more distantly related to us. Although remains of these mysterious early humans have mostly been discovered at the Denisova Cave in the Altai Mountains in Siberia, DNA analysis has shown the ancient people were widespread across Asia. Scientists were able to analyse DNA from a tooth and from a finger bone excavated in the Denisova cave in southern Siberia. The discovery was described as 'nothing short of sensational.' In 2020, scientists reported Denisovan DNA in the Baishiya Karst Cave in Tibet. This discovery marked the first time Denisovan DNA had been recovered from a location that is outside Denisova Cave. How widespread were they? Researchers are now beginning to find out just how big a part they played in our history. DNA from these early humans has been found in the genomes of modern humans over a wide area of Asia, suggesting they once covered a vast range. They are thought to have been a sister species of the Neanderthals, who lived in western Asia and Europe at around the same time. The two species appear to have separated from a common ancestor around 200,000 years ago, while they split from the modern human Homo sapien lineage around 600,000 years ago. Last year researchers even claimed they could have been the first to reach Australia. Aboriginal people in Australia contain both Neanderthal DNA, as do most humans, and Denisovan DNA. This latter genetic trace is present in Aboriginal people at the present day in much greater quantities than any other people around the world. How advanced were they? Bone and ivory beads found in the Denisova Cave were discovered in the same sediment layers as the Denisovan fossils, leading to suggestions they had sophisticated tools and jewellery. Professor Chris Stringer, an anthropologist at the Natural History Museum in London, said: 'Layer 11 in the cave contained a Denisovan girl's fingerbone near the bottom but worked bone and ivory artefacts higher up, suggesting that the Denisovans could have made the kind of tools normally associated with modern humans. 'However, direct dating work by the Oxford Radiocarbon Unit reported at the ESHE meeting suggests the Denisovan fossil is more than 50,000 years old, while the oldest 'advanced' artefacts are about 45,000 years old, a date which matches the appearance of modern humans elsewhere in Siberia.' Did they breed with other species? Yes. Today, around 5 per cent of the DNA of some Australasians – particularly people from Papua New Guinea – is Denisovans. Now, researchers have found two distinct modern human genomes - one from Oceania and another from East Asia - both have distinct Denisovan ancestry. The genomes are also completely different, suggesting there were at least two separate waves of prehistoric intermingling between 200,000 and 50,000 years ago. But what they did not expect to find was individuals from East Asia carry a uniquely different type.

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