Sarepta shares slump on reports of third patient death this year
This is the third death this year for Sarepta after two teenage boys who had received Elevidys, a gene therapy approved to treat a rare condition called Duchenne muscular dystrophy, died of liver failure.
A 51-year-old man enrolled in an early-stage trial of Sarepta's gene therapy, SRP-9004, for the treatment of limb-girdle muscular dystrophy (LGMD) died from acute liver failure last month, according to several media reports.
LGMD includes a group of genetic disorders that primarily weaken the hip and shoulder muscles.
The news of the death was first reported by pharma website BioCentury on Thursday evening.
On Wednesday, Sarepta announced a restructuring plan that included 500 job cuts and halting development of several gene therapies for limb-girdle muscular dystrophy.
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