Harmony Biosciences Preclinical Data for Narcolepsy Drug BP1.15205 Shows Promise
The data showed significant wake-promoting and cataplexy-suppressing effects in a standard transgenic mouse model of narcolepsy type 1. Narcolepsy is a chronic neurological disease affecting ~170,000 Americans, primarily characterized by excessive daytime sleepiness/EDS and cataplexy, along with other manifestations of REM sleep dysregulation.
A close-up of a pharmaceutical drug bottle, showcasing the potential of the company's innovative therapies.
The disease is often caused by the loss of hypocretin/orexin, a neuropeptide crucial for sleep-wake stability. BP1.15205 features a new and unique chemical scaffold optimized for high potency, which showed statistically significant wake-promoting effects at very low oral doses in the transgenic mouse model. These findings support dosing flexibility to potentially treat all 3 central disorders of hypersomnolence at low doses, which could offer an optimized benefit-risk profile.
Harmony Biosciences Holdings Inc. (NASDAQ:HRMY) is a commercial-stage pharmaceutical company that develops & commercializes therapies for patients with rare & other neurological diseases in the US.
While we acknowledge the potential of HRMY as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the .
READ NEXT: and .
Disclosure: None. This article is originally published at Insider Monkey.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
17 minutes ago
- Yahoo
Alphabet Inc. (GOOGL): 'This Stock Should Be Up Much More,' Says Jim Cramer
We recently published . Alphabet Inc. (NASDAQ:GOOGL) is one of the stocks Jim Cramer recently discussed. Cramer regularly discussed tech mega-cap Alphabet Inc. (NASDAQ:GOOGL) ahead of its earnings. The firm's shares have reversed course in July and are up by 1.9% year-to-date, primarily due to July's 9.9% gain. Before the report, Cramer was explicit in sharing that he regretted selling Alphabet Inc. (NASDAQ:GOOGL)'s stock. This time, he discussed the firm's businesses and shared that the stock should be higher after the earnings: [GOOGL]'[On earnings report] Yeah, look cloud was important. I think the big focus is frankly, uh, that paid clicks picked up 4%. I mean I was thinking paid clips might be down, I was worried that I felt that this was the beginning of the erosion and the cannibalization versus Gemini. That was completely wrong. YouTube up 200 million. Really, really fantastic. . . .Look the story here is this that the more chips that they get, better they're doing. They have so much demand I was quite surprised. 20 New Technology Trends for 2024 'This stock should be up much more than that. While we acknowledge the potential of GOOGL as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the . READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now. Disclosure: None. This article is originally published at Insider Monkey. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
17 minutes ago
- Yahoo
Tesla, Inc. (TSLA)'s 'A Cult Stock,' Says Jim Cramer
We recently published . Tesla, Inc. (NASDAQ:TSLA) is one of the stocks Jim Cramer recently discussed. Tesla, Inc. (NASDAQ:TSLA) continues to face a horrible time on the stock market in 2025. The firm's shares have lost 16.7% year-to-date and fell by 8.2% after its latest earnings report, which missed analyst revenue and earnings estimates. The results were so bad that even Cramer, who believes that Tesla, Inc. (NASDAQ:TSLA)'s potential is in emerging technologies such as robotics, was forced to do somewhat of a turnaround: '[on revenue, vehicle sold, carbon credit all down] Okay, so you listen to the conference call, and they made it so that those don't matter. All that matters is self drive, autonomous. I'm not kidding. Robotaxi, uh, Austin, California. And then there's some lines, which says, where he's saying, and David you'll get a kick out of this I'm sure, he's talking about like in a few years like everyone's gonna be in this. The robotaxi's like going great. I mean, it's not doing anything. This was a call that was a fatuous call. David, I left out Turkey, number one. Netherlands and Austria. I knew that Austrian market, that was it. 'It's a cult stock. . . This was not the kind of conference call that I expected. I did not expect an immediate pivot to robots and the self driving and the robotaxi. While we acknowledge the potential of TSLA as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the . READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now. Disclosure: None. This article is originally published at Insider Monkey. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
17 minutes ago
- Yahoo
Honeywell International Inc. (HON): 'I Think You Buy' It, Says Jim Cramer
We recently published . Honeywell International Inc. (NASDAQ:HON) is one of the stocks Jim Cramer recently discussed. Honeywell International Inc. (NASDAQ:HON) is one of the biggest industrial conglomerates in America. Its shares are flat year-to-date after a major 6% dip in July after the latest earnings results. The shares fell because despite the fact that the firm reported $10.4 billion in sales and $2.75 in EPS to beat analyst estimates of $10.1 billion and $2.66, investors were looking for a robust earnings performance to drive its guidance raise. Here's what Cramer said about Honeywell International Inc. (NASDAQ:HON) after the earnings: 'Okay, so Honeywell is splitting into three different companies. Some people feel that the cash flow is weaker, uh, I don't feel that this is nearly as and. . .I think you buy Honeywell. Only one division was weaker. This was automation. The stock tends to sell off when they report. And then it spends the next three weeks recovering. I think Honeywell is fine. Charitable trust owns it, it's a big win. It will continue to be a big win. This is a major overreaction to something that shouldn't be happening. Right now, shouldn't be happening. Down 15 you buy it. Copyright: zenstock / 123RF Stock Photo '[On guidance raise] Yes that's what matters. And people just always seize at whatever's most negative. They're breaking up into three companies. He's bringing out value. This is very short sighted. Vimal Kapoor doing a great job. Buy the stock. Overreaction to something that's not even negative for heaven's sake. Unbelievable how poorly the stock acts on the day it reports and then it spends the rest of the time, climbing. Buy it.' While we acknowledge the potential of HON as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the . READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now. Disclosure: None. This article is originally published at Insider Monkey. Sign in to access your portfolio
