Miracle microdosing trick celebrities use to get thicker hair revealed. This is how I plumped up my volume and length - and it's guaranteed to work for every woman, says ALICE SMELLIE
As we know, volume vanishes from all the wrong places as we age and, sadly, that includes once-luxurious locks, which might become thinner, flat and dull looking.
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The Guardian
29 minutes ago
- The Guardian
RFK Jr's health department to halt $500m in mRNA vaccine research
The US Department of Health and Human Services said on Tuesday it would terminate 22 federal contracts for mRNA-based vaccines, questioning the safety of a technology credited with helping end the Covid pandemic and saving millions of lives. The unit, Biomedical Advanced Research and Development Authority, helps companies develop medical supplies to address public health threats, and had provided billions of dollars for development of vaccines during the Covid-19 pandemic. HHS said the wind-down includes cancellation of a contract awarded to Moderna for the late-stage development of its bird flu vaccine for humans and the right to purchase the shots, as previously reported in May. The US health agency said it was also rejecting or canceling multiple pre-award solicitations, including proposals from Pfizer, Sanofi Pasteur, CSL Seqirus, Gritstone and others. In total, the affected projects are worth 'nearly $500 million', the Department of Health and Human Services (HHS) said. Certain late-stage projects were excluded from the move 'to preserve prior taxpayer investment'. This is the latest development under US health secretary Robert F Kennedy Jr, a longtime vaccine skeptic who has been making sweeping changes to reshape vaccines, food and medicine policies. 'We reviewed the science, listened to the experts, and acted,' Kennedy said in a statement. Kennedy said the HHS is terminating these programs because data show these vaccines 'fail to protect effectively against upper respiratory infections like COVID and flu', but did not offer scientific evidence. 'We're shifting that funding toward safer, broader vaccine platforms that remain effective even as viruses mutate,' Kennedy said. HHS said the decision follows a comprehensive review of mRNA-related investments initiated during the Covid-19 public health emergency. Since taking office, Kennedy, who spent two decades sowing misinformation around immunization, has overseen a major overhaul of US health policy – firing, for example, a panel of vaccine experts that advise the government and replacing them with his own appointees. In its first meeting, the new panel promptly voted to ban a longstanding vaccine preservative targeted by the anti-vaccine movement, despite its strong safety record. He has also ordered a sweeping new study on the long-debunked link between vaccines and autism. Unlike traditional vaccines, which often use weakened or inactivated forms of the target virus or bacteria, mRNA shots deliver genetic instructions into the host's cells, prompting them to produce a harmless decoy of the pathogen and train the immune system to fight the real thing. Though in development for decades, mRNA vaccines were propelled from lab benches to widespread use through Donald Trump's Operation Warp Speed – a public-private partnership led by Barda that poured billions into companies to accelerate development. The technology's pioneers, Katalin Karikó and Drew Weissman, were awarded the 2023 Nobel prize in medicine for their work contributing 'to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times'.
The Independent
an hour ago
- The Independent
4 people die in crash of medical transport plane on Navajo Nation in northern Arizona
A small medical transport plane crashed and caught fire Tuesday on the Navajo Nation in northern Arizona, killing four people, the tribe said in a statement. A Beechcraft 300 from the CSI Aviation company left Albuquerque, New Mexico, with four medical personnel on board, according to the Federal Aviation Administration and other agencies. It crashed in the early afternoon near the airport in Chinle, about 300 miles (483 kilometers) northeast of Phoenix. 'They were trying to land there and unfortunately something went wrong,' district Police Commander Emmett Yazzie said. The crew was planning pick up a patient who needed critical care from the federal Indian Health Service hospital in Chinle, said Sharen Sandoval, director of the Navajo Department of Emergency Management. She said the plan was to return to Albuquerque. The patient's location and condition were not known Tuesday evening. Tribal authorities began receiving reports at 12:44 p.m. of black smoke at the airport, Sandoval said. The cause of the crash wasn't known, the tribe said. The National Transportation Safety Board and the FAA are investigating. Navajo Nation President Buu Nygren said in a social media post that he was heartbroken to learn of the crash. 'These were people who dedicated their lives to saving others, and their loss is felt deeply across the Navajo Nation,' he said. Medical transports by air from the Navajo Nation are common because most hospitals are small and do not offer advanced or trauma care. The Chinle airport is one of a handful of airports that the tribe owns and operates on the vast 27,000 square-mile (70,000 square-kilometer) reservation that stretches into Arizona, New Mexico and Utah -- the largest land base of any Native American tribe. In January, a medical transport plane crashed in Philadelphia, killing eight people. The National Transportation Safety Board, which is investigating the crash, has said the voice recorder on that plane was not working. ___ Associated Press journalists Hannah Schoenbaum in Salt Lake City and Felicia Fonseca in Flagstaff, Arizona, contributed to this report.
Medical News Today
an hour ago
- Medical News Today
Your FAQs around generalized pustular psoriasis
Generalized pustular psoriasis is a severe form of psoriasis that can cause body-wide symptoms and may require immediate medical pustular psoriasis (GPP), also known as von Zumbusch psoriasis, is a rare type of GPP affects an estimated 1 to 7 people out of every million. It features episodes or 'flares' of erythroderma, widespread skin inflammation and redness or other skin color changes. These flares develop with sterile (not caused by infection), fluid-filled blisters or a flare, pustules break open, and the skin can become dry and painful. It may crack, peel, or scale and may resemble a is an immune-mediated condition caused by dysfunction in the immune system. Unusual immune responses to triggers such as stress, medication use, or infections can set off a chain of severe inflammatory reactions throughout the body. GPP often has identifiable triggers, but it can also happen without any obvious people experience severe systemic symptoms in addition to skin inflammation, including fever, chills, muscle weakness, and fatigue. If left untreated, GPP can cause life threatening complications like organ on to find out the answers to some of your most pressing questions about is the outlook for generalized pustular psoriasis?GPP is a chronic condition. It can be managed, but it may never be fully cured. As many as 80% of people experience relapses, and most have at least one episode outlook during a flare depends largely on how quickly a person receives treatment. Severe inflammation can cause tissue damage and affect internal organs like the heart, lungs, or kidneys. In some cases, this may result in sepsis, a life threatening complication that requires urgent care. Seeking treatment as soon as possible can help shorten the duration of a GPP flare and lower the risk of serious between flares, GPP can affect long-term health. People with GPP have a higher risk of cardiovascular conditions and other systemic complications, which can affect quality of life and life to a 2025 study, people with GPP have about four times the risk of death from any cause compared to the general is the best treatment for generalized pustular psoriasis?Everyone living with GPP has different factors that can affect their treatment plan. A doctor will consider a person's age, family history, genetics, and other health conditions when recommending a flare, first-line treatments usually include medications that target the immune system. These drugs work by blocking or calming overactive inflammatory example is spesolimab (Spevigo), a monoclonal antibody that blocks interleukin-36 (IL-36) receptors. IL-36 is a pro-inflammatory molecule, known as a cytokine, that becomes overactive in GPP. It triggers systemic inflammation and stimulates the production of neutrophils, which accumulate in the skin and create spesolimab is the only medication approved by the Food and Drug Administration (FDA) specifically for the treatment of may also use other medications that modify immune responses or control inflammation, such as:infliximaboral retinoidsapremilastmethotrexatecyclosporineFor mild symptoms or when GPP is well managed, doctors may recommend more conservative treatments. These can include keeping the skin hydrated, using topical corticosteroids, and prescribing antibiotics if there is an a medication triggers the flare, stopping that medication is also an important part of the do you stop pustules from spreading?Immediate treatment helps stop GPP pustules from in GPP are sterile. They form because of overactive inflammatory processes in the body. Itching pustules or having pustules break open is not what causes pustules to spread (although this can increase the risk of secondary infection).Interrupting the inflammatory chain with medications like spesolimab during a flare will help bring pustules under control. Applying cool compresses, keeping skin clean and moisturized, and avoiding irritants like rough fabric can help improve the overall health of the skin and manage pustular psoriasis lead to sepsis?Generalized pustular psoriasis can lead to is a severe, life threatening inflammatory reaction to an infection that spreads through the bloodstream. It can cause symptoms such as: feverrapid heartbeatrapid breathinga dangerous drop in blood pressureconfusionorgan damageIn GPP, several factors can increase the risk of sepsis. Open skin from pustules, cracks, or scratching allows bacteria, viruses, or fungi to cross the skin barrier and enter the bloodstream. Medications that suppress the immune system, such as methotrexate or infliximab, can also make it harder for the body to fight these pathogens enter the bloodstream, they can travel throughout the body, triggering a widespread inflammatory response known as sepsis happen during every generalized pustular psoriasis flare?Sepsis can occur during a flare, but it does not happen every time a person with GPP experiences a in GPP are believed to be caused by a 'cytokine storm.' A cytokine storm happens when the immune system becomes overactive and releases too many pro-inflammatory molecules at once. Infection can trigger a cytokine storm, but it is not the only cause. Cytokine storms in GPP can happen any time the immune system is overactivated, even without an however, always results from an infection. It also involves a cytokine storm, but in this case, the overactivation of cytokines is a direct response to that infection. In conditions like GPP, existing cytokine dysfunction can make a sepsis-related cytokine storm more pustular psoriasis is a rare form of psoriasis that causes widespread areas of red, inflamed skin covered with sterile, fluid-filled pustules. GPP can be life threatening. It causes severe, body-wide inflammation that may damage tissues and lead to organ treatment can help slow the spread of pustules and lower the risk of serious complications. Doctors typically treat GPP with medications that interrupt or block overactive immune responses. Spesolimab (Spevigo) is the only drug currently approved by the FDA specifically for the treatment of GPP.
