Al Jalila Children's Hospital crosses 100 treatments for Spinal Muscular Atrophy
Dr Mohamed Al Awadhi, Executive Director of the Dubai Health Women and Children's Campus, said, "Reaching more than 100 treated cases of SMA reflects Dubai Health's commitment to making world-class care accessible to all children. At Al Jalila Children's Hospital, we follow an integrated, patient-centred approach that supports every phase of the treatment journey. Every step is managed with precision and compassion to put the patient first. Yaqeen's case highlights the strength of our multidisciplinary model and our commitment to ensuring that children with complex conditions like SMA receive the highest standard of care under one roof.'
Dr Haitham Elbashir, Consultant Pediatric Neurorehabilitation at Al Jalila Children's Hospital, said, "Zolgensma is a transformative therapy that offers children with SMA the chance to regain strength and function early in life.'
The completion of over 100 SMA treatments at Al Jalila Children's reflects the strength of Dubai Health's specialised pediatric services and its commitment to delivering high-quality care for children with complex medical needs.
WAM
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Hi Dubai
17 hours ago
- Hi Dubai
Dubai Health Scientists Publish First Arab Pangenome Reference, Advancing Precision Medicine in the Region
Scientists at the Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), the academic and research arm of Dubai Health, have published the first-ever Arab Pangenome Reference. The landmark study, featured in the peer-reviewed journal Nature Communications , sets a new benchmark for precision medicine and personalised healthcare in the region. The breakthrough aligns with the UAE's National Genome Strategy, a 10-year plan launched by the Emirates Genome Council in 2023 to enhance preventive and precision-based care using genomic science. The Arab Pangenome Reference is a foundational contribution to this vision. Built using high-quality DNA sequencing data from 53 individuals of diverse Arab descent residing in the UAE, the reference fills a critical gap in global genetic databases, which have long underrepresented Arab populations. The research uncovered over 110 million base pairs of novel DNA sequences and identified nearly 9 million small genetic variants, along with over 235,000 large structural differences unique to Arab genomes. These findings are significant not just for the region, but for the global scientific community, said Prof. Alawi Alsheikh-Ali, Director General of the Dubai Health Authority and co-author of the study. We are enabling more precise and equitable healthcare by building a genome reference that reflects our population. One of the study's key discoveries includes the identification of a duplicated gene, TAF11L5, which was found to be highly enriched in Arab individuals but absent in current global references. This gene may influence the activity of other genes, with potential implications for disease risk and treatment response. The research was conducted entirely in-house at MBRU's Center for Applied and Translational Genomics (CATG). This integration allowed us to control the full research pipeline—from sequencing to bioinformatics—ensuring top-tier quality, said Dr. Hanan Al Suwaidi, Acting Provost at MBRU and co-author of the study. As part of the initiative, the team also developed a new open-source bioinformatics tool called PanScan, which facilitates the detection of gene duplications and complex DNA structures. The tool is now publicly accessible on GitHub, enabling scientists worldwide to benefit from the work. Dr. Mohammed Uddin, Director of CATG and senior author of the study, noted: This pangenome reference is a major step in understanding Arab genetic diversity. It will be a critical asset for both research and clinical diagnostics. The study not only enhances the scientific understanding of Arab genomics but also reinforces Dubai Health's long-term commitment to world-class research and innovation in healthcare. MBRU's research strategy continues to contribute meaningful data to international scientific efforts, while ensuring local populations are represented in global health advancements. The full study can be accessed at Nature Communications. News Source: Dubai Media Office
Emirates 24/7
a day ago
- Emirates 24/7
Dubai Health scientists publish first Arab Pangenome Reference, marking a milestone for precision medicine
Scientists at the Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), the learning and discovery arm of Dubai Health, have published the first Arab Pangenome Reference, marking a major milestone in both regional and global genomic research. The study, released in Nature Communications, a leading scientific journal, provides a crucial foundation for advancing precision medicine and personalised healthcare for Arab populations, while also supporting the UAE's National Genome Strategy, a 10-year initiative launched in 2023 by the Emirates Genome Council to advance personalised, preventive, and precision healthcare through cutting-edge genomic science. The reference was built using high-quality DNA sequencing from 53 people of diverse Arab backgrounds in the UAE. The work, conducted in MBRU's state-of-the-art Center for Applied and Translational Genomics (CATG), uncovered over 110 million base pairs of novel DNA sequences and identified nearly nine million small differences and more than 235,000 larger structural differences specific to Arab populations that have not been reported before. These findings are significant, as global DNA references have historically underrepresented Arab populations — a gap this research helps to close. The Arab Pangenome Reference supports national and regional precision medicine initiatives by enabling the development of population-specific biomarkers, risk models, and therapeutic targets. One notable discovery was the duplicated gene TAF11L5, found highly enriched in Arab individuals studied but absent from global references. This gene may play a role in regulating other genes and could have implications for understanding disease risk and individual variation in treatment response. Professor Alawi Alsheikh-Ali, Director General, Dubai Health Authority, and co-author of the study, said: 'This achievement strengthens the UAE's position in genomic science. By building a reference that reflects the genetic diversity of Arab populations, we are enabling more precise and equitable healthcare. It's a foundational step towards realising the goals of our National Genome Strategy and ensuring that future medical innovations are shaped by data from our own communities.' Dr. Hanan Al Suwaidi, Acting Provost of MBRU, and co-author of the study said: 'The capabilities of the CATG lab were central to the success of this project. From genetic sequencing to advanced bioinformatics, every stage of the research was completed in-house. This level of integration gave us full control over quality and timelines, reflecting Dubai Health's commitment to building world-class infrastructure and fostering national scientific leaders." While genomic research has advanced rapidly over the past two decades, much of the foundational data has come from a narrow subset of global populations. This has created blind spots in how genetic risk is understood and addressed across different communities. The Arab Pangenome Reference contributes to a growing international effort to correct this imbalance by introducing high-quality data from a historically underrepresented population. Dr. Mohammed Uddin, Director of CATG and Associate Professor of Genetics at MBRU, and senior author of the study, said: 'This pangenome reference marks a major advancement in our understanding of Arab genomic diversity. It serves as a critical resource for both research discovery and clinical genome diagnostics, with lasting impact for future generations across the region.' The project also developed 'PanScan', a bioinformatics tool to support more complex analysis of human pangenomes. Although not the central focus of the study, PanScan enables researchers to detect gene duplications, novel DNA changes, and complex DNA structures. Now publicly available on GitHub, a common resource used by scientists worldwide, the tool was created to support the Arab Pangenome Reference and similar efforts globally. Dr. Nasna Nassir, lead author of the study and Assistant Professor at MBRU, said: 'To support the Arab Pangenome Reference study, we developed PanScan, a tool designed to identify novel variants, gene duplications, and complex haplotype patterns specific to Arab populations. PanScan was key to uncovering unique genomic insights in our study and is now publicly available to support similar research globally.' The research reflects Dubai Health's commitment to advancing learning and discovery through MBRU. The university's research strategy is focused on contributing to global scientific progress. By investing in foundational genomic research, Dubai Health is helping to ensure that Arab populations are represented in the future of precision healthcare. The full study is available at:
Middle East Eye
4 days ago
- Middle East Eye
Palestinian Ministry of Health condemns Israeli arrest of Gaza hospital director
The Palestinian Ministry of Health has confirmed that Dr Marwan al-Hams, director of the Abu Yousef al-Najjar Hospital in Rafah, has been arrested by Israeli Special Forces. The Ministry condemned the arrest as a "cowardly act", and described al-Hams as "one of the most prominent humanitarian and medical voices" in Gaza. Israel has frequently targeted health workers and hospital infrastructure during its ongoing war on Gaza. The arrest follows Israel's killing of prominent Palestinian doctor Marwan al-Sultan in a missile strike on his home on 2 July.
