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Groundbreaking remote robotic surgery: Patient was in Africa; doctor was in Florida

Groundbreaking remote robotic surgery: Patient was in Africa; doctor was in Florida

Yahoo17-06-2025
Fernando da Silva, who lives in the southern African nation of Angola, was diagnosed with prostate cancer in March.
Three months later, he underwent a procedure to cut out the cancer from a surgeon who has done tens of thousands of similar procedures.
But the doctor performing the surgery was 7,000 miles away -- in Orlando, Florida.
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Da Silva was the first patient of a groundbreaking human clinical trial approved by the U.S. Food and Drug Administration to test transcontinental robotic telesurgery.
"We've been working on this really for two years," Dr. Vipul Patel, the medical director of the Global Robotic Institute at Orlando's Advent Health, told ABC News after completing the surgery. "We traveled the globe, looking at the right technologies."
ABC News' medical correspondent Dr. Darien Sutton was granted exclusive access to the remote surgery in a special report that aired June 16 on ABC News Live Prime with Linsey Davis.
Prostatectomy, a surgical procedure that removes part or all the prostate, has more recently been done with a sophisticated robotic surgery system.
Instead of scrubbing into the operating room, surgeons operate on patients via a multimillion-dollar robot with enhanced visuals and nimble controls.
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Using a robot allows for the procedure to be less invasive, more precise and typically comes with a faster recovery time.
While surgeons are typically near the patient they are operating on, Patel and his team were eager to test whether the surgery could be done long distance using a fiber optic cables.
"I think the humanitarian implications are enormous," Patel said. "Internationally, obviously, there's so many underserved areas of the world."
Patel also pointed out that rural areas within the U.S. could benefit by helping surgeons learn new procedures from a distance or helping patients from a distance if complications arise during surgery.
"Emergency room physicians will have technology that can be remotely accessible to surgeons, maybe even in the ambulance, where people can get remote interventions if they can't make it to the hospital," Patel said.
Patel had his surgical team in the operating room in Angola and were prepared for any potential issues, in case they arose.
"We made sure we had plan A, B, C, and D. I always have my team where the patient is," Patel said. "So, in case something happened with" the telecommunications, "the team would just take over and finish the case and do it safely."
Patel said he plans to submit the data from the surgery back to the FDA for teams there to review in the hopes he will be able to do more telesurgeries.
"It was a small step for a surgeon, but it was huge leap for health care," he added.
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Previous data in pancreatic ductal adenocarcinoma (PDAC) and non-small cell lung cancer (NSCLC) indications have shown promising results for nadunolimab in combination with chemotherapy in these indications [3,4], and nadunolimab is granted Fast Track designation from the U.S. Food and Drug Administration (FDA) in PDAC patients with high expression levels of IL1RAP. Nadunolimab is currently being tested inpatients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in an investigator-initiated clinical study at The University of Texas MD Anderson Cancer Center. More details of the TRIFOUR study will be communicated at an upcoming scientific conference. References[1] O'Shaughnessy, J Clin Oncol 2014, 32:3840-3847[2] Cortes N Engl J Med 2022, 387: 217-226[3] van Cutsem et al, Clin Cancer Res 2024, 30: 5293-5303[4] Paulus et al, Lung Cancer 2025, For further information, please contactDamian Marron, Interim CEOTelephone: +46 (0)46-275 62 60E-mail: This information is information that Cantargia is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact persons set out above, at 2025-07-17 21:30 CEST. About CantargiaCantargia AB (publ), reg. no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases and has established a platform based on the protein IL1RAP, involved in a number of cancer forms and inflammatory diseases. Cantargia's oncology program, the antibody nadunolimab (CAN04), is being studied clinically, primarily in combination with chemotherapy with a focus on pancreatic cancer, non-small cell lung cancer and triple-negative breast cancer. Positive data for the combinations indicate stronger efficacy than would be expected from chemotherapy alone. Cantargia's second development program, the antibody CAN10, blocks signaling via IL1RAP in a different manner than nadunolimab and addresses treatment of serious autoimmune/inflammatory diseases, with initial focus on hidradenitis suppurativa and systemic sclerosis. Cantargia is listed on Nasdaq Stockholm (ticker: CANTA). More information about Cantargia is available at About nadunolimab (CAN04)The antibody nadunolimab binds strongly to its target IL1RAP and functions by inducing ADCC and blocking IL-1α and IL-1β signaling. Nadunolimab can thereby counteract the IL-1 system which contributes to the immune suppressive tumor microenvironment and the development of resistance to chemotherapy. Nadunolimab is investigated in multiple clinical trials; the phase I/IIa trial CANFOUR, NCT03267316, evaluates nadunolimab in combination with standard chemotherapies in patients with pancreatic ductal adenocarcinoma (PDAC) (gemcitabine/nab-paclitaxel) or non-small cell lung cancer (NSCLC) (platinum-based chemotherapies). Positive data show durable responses for combination therapy in 73 PDAC patients, resulting in a median iPFS of 7.2 months and median OS of 13.2 months. An even higher median OS of 14.2 months was observed in a subgroup of patients with high tumor levels of IL1RAP. Strong efficacy was also observed in 40 NSCLC patients with median PFS of 7.2 months and a response rate of 55%; even higher responses were observed in non-squamous NSCLC patients. Early efficacy data from the phase 1b/2 trial TRIFOUR, NCT05181462, also shows signs of promising efficacy in TNBC with a 60% response rate for nadunolimab combined with carboplatin/gemcitabine. About GEICAMGEICAM is the leader group in breast cancer research in Spain with a recognized worldwide prestige. It is formed by more than 900 experts, who work in 220 institutions throughout its establishment in 1995 until now GEICAM has performed more than a hundred of studies in which almost 68,000 women and men have has a large multidisciplinary team specialized in the management of clinical trials and other studies, which collaborates with clinical researchers in the design and implementation of clinical trials, as well as in their execution and dissemination in forums and high-impact scientific more information, you can visit the official website or follow us on Twitter @GEICAM, @GEICAMujer, and on AttachmentsCantargia announces preliminary topline efficacy results from the phase 2 TRIFOUR trial of nadunolimab in advanced triple-negative breast cancer (TNBC) SOURCE: Cantargia View the original press release on ACCESS Newswire

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