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Breakthrough cure for baldness: 100% of male mice regrew fur with new treatment

Breakthrough cure for baldness: 100% of male mice regrew fur with new treatment

New York Post19-06-2025
It's the bald truth.
Researchers at San Carlos Clinical Hospital in Madrid have developed a cure for androgenetic alopecia, commonly known as pattern hair loss.
An estimated 80 million Americans — 50 million men and 30 million women — experience some form of alopecia, although it affects women differently than men.
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Researchers at San Carlos Clinical Hospital in Madrid have developed a cure for androgenetic alopecia — commonly known as pattern hair loss.
Phimchanok – stock.adobe.com
Men usually go through a receding hairline and bald spots, whereas women get thinner at the part line but rarely go fully bald.
In the study — published in the journal Stem Cell Research and Therapy — researchers used a combo of fat‑tissue-derived stem cells and the energy molecule ATP to reverse hair loss in mice, with shocking results.
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All of the male mice grew back their coats. Half had full regrowth, while the other half had intensive regrowth.
Among females, a whopping 90% saw intense or complete hair revival.
Eduardo López Bran, head of the Dermatology Department at the Hospital Clínico San Carlos, explained that their special method 'stimulates hair regeneration by combining the regenerative capacity of the former with the energy provided by the latter. This synergy favors the recovery of the hair follicle, promoting hair growth.'
While the findings will need to be replicated in human trials, the results pave a promising way forward in the fight against hair loss.
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All of the male mice grew back their coats. Among females, a whopping 90% saw intense or complete hair revival.
Javier – stock.adobe.com
'In the future, we will be able to offer new solutions that allow us to meet patients' expectations, allowing them access to new treatments that prioritize their well-being,' Eduardo López Bran said.
It's an exciting development in an area where there's plenty of room for growth.
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While hair transplant surgery is on the rise, many people don't realize that it actually often takes several procedures to achieve the desired result.
'An alarming trend is patients who now go to perform a hair transplant by a physician who does not consult the patient about his or her hair loss nor is he actively involved in the surgery,' Texas facial plastic surgeon and hair restoration expert Dr. Samuel Lam previously told The Post.
He noted that this troubling practice is 'most rampant' in Turkey — where hair transplant surgery has exploded due to its relative affordability — but it is 'also extremely prevalent in the US, unfortunately.'
Meanwhile, some men have been vocal about how post-finasteride syndrome (PFS) — a condition in which someone experiences severe side effects after they stop using finasteride — has completely upended their lives.
One woman even recently chronicled how PFS destroyed her husband's sex drive — and ended their marriage.
Researchers are racing to find new, safer and more affordable hair loss treatments, inventing non-hormonal pills and gummies and repurposing older drugs to find a sustainable solution.
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Rural hospitals brace for financial hits or even closure under Republicans' $1 trillion Medicaid cut
Rural hospitals brace for financial hits or even closure under Republicans' $1 trillion Medicaid cut

Los Angeles Times

timean hour ago

  • Los Angeles Times

Rural hospitals brace for financial hits or even closure under Republicans' $1 trillion Medicaid cut

OMAHA, Neb. — Tyler Sherman, a nurse at a rural Nebraska hospital, is used to the area's aging farmers delaying care until they end up in his emergency room. Now, with the Trump administration planning around $1 trillion in Medicaid cuts over 10 years, he fears those farmers and the more than 3,000 residents of Webster County could lose not just the ER, but also the clinic and nursing home tied to the hospital. 'Our budget is pretty heavily reliant on the Medicaid reimbursement, so if we do see a cut of that, it'll be difficult to keep the doors open,' said Sherman, who works at Webster County Community Hospital in the small Nebraska town of Red Cloud just north of the Kansas border. If those facilities close, many locals would see their five-minute trip to Webster County hospital turn into a nearly hour-long ride to the nearest hospital offering the same services. 'That's a long way for an emergency,' Sherman said. 'Some won't make it.' States and rural health advocacy groups warn that cutting Medicaid — a program serving millions of low-income and disabled Americans — would hit already fragile rural hospitals hard and could force hundreds to close, stranding some people in remote areas without nearby emergency care. More than 300 hospitals could be at risk for closure under the 'Big Beautiful Bill Act,' according to an analysis by the Cecil G. Sheps Center at the University of North Carolina at Chapel Hill, which tracks rural hospital closures. Even as Congress haggled over the controversial bill, a health clinic in the southwest Nebraska town of Curtis announced Wednesday it would close in the coming months, in part blaming the anticipated Medicaid cuts. Bruce Shay of Pomfret, Conn., fears he and his wife could be among those left in the lurch. At 70, they're both in good health, he said. But that likely means that if either needs to go to a hospital, 'it's going to be an emergency.' Day Kimball Hospital is nearby in Putnam, but it has faced recent financial challenges. Day Kimball's CEO R. Kyle Kramer acknowledged that the bill passed Thursday — estimated to cut federal Medicaid spending in rural areas by $155 billion over 10 years — would further hurt his facility's bottom line. Roughly 30% of Day Kimball's current patients receive Medicaid benefits, a figure that's even higher for specific, critical services like obstetrics and behavioral health. 'An emergency means I'm 45 minutes to an hour away from the nearest hospital, and that's a problem,' Shay said. And he and his wife wouldn't be the only ones having to make that trip. 'You've got, I'm sure, thousands of people who rely on Day Kimball Hospital. If it closed, thousands of people would have to go to another hospital,' he said. 'That's a huge load to suddenly impose on a hospital system that's probably already stretched thin.' Rural hospitals have long operated on the financial edge, especially in recent years as Medicaid payments have continuously fallen below the actual cost to provide healthcare. More than 20% of Americans live in rural areas, where Medicaid covers 1 in 4 adults, according to the nonprofit KFF, which studies healthcare issues. President Trump's $4.5-trillion tax breaks and spending cuts plan would worsen rural hospitals' struggles by cutting a key federal program that helps states fund Medicaid payments to healthcare providers. To help offset the lost tax revenue, the package includes $1.2 trillion in cuts to Medicaid and other social safety net programs — cuts they insist only root out fraud and waste in the system. But public outcry over Medicaid cuts led Republicans to include a provision that will provide $10 billion annually to buttress rural hospitals over the next five years, or $50 billion in total. Many rural hospital advocates are wary that it won't be enough to cover the shortfall. Carrie Cochran-McClain, chief policy officer with the National Rural Health Assn., said rural hospitals already struggle to break even, citing a recent American Hospital Assn. report that found that hospitals in 2023 got nearly $28 billion less from Medicaid than the actual cost of treating Medicaid patients. 'We see rural hospitals throughout the country really operating on either negative or very small operating margins,' Cochran-McClain said. 'Meaning that any amount of cut to a payer — especially a payer like Medicaid that makes up a significant portion of rural provider funding — is going to be consequential to the rural hospitals' ability to provide certain services or maybe even keep their doors open at the end of the day.' A KFF report shows 36 states losing $1 billion or more over 10 years in Medicaid funding for rural areas under the Republican bill, even with the $50 billion rural fund. No state stands to lose more than Kentucky. The report estimates the Bluegrass State would lose a whopping $12.3 billion — nearly $5 billion more than the next state on the list. That's because the bill ends Kentucky's unique Medicaid reimbursement system and reduces it to Medicare reimbursement levels. Kentucky currently has one of the lowest Medicare reimbursement rates in the country. It also has one of the highest poverty rates, leading to a third of its population being covered by Medicaid. Kentucky Gov. Andy Beshear, a two-term Democrat widely seen as a potential candidate for president in 2028, said the bill would close 35 hospitals in his state and pull healthcare coverage for 200,000 residents. 'Half of Kentucky's kids are covered under Medicaid. They lose their coverage and you are scrambling over that next prescription,' Beshear said during an appearance on MSNBC. 'This is going to impact the life of every single American negatively. It is going to hammer our economy.' Beck and Haigh write for the Associated Press. Haigh reported from Hartford, Conn.

See clearly underwater with the best swim goggles
See clearly underwater with the best swim goggles

Chicago Tribune

time2 hours ago

  • Chicago Tribune

See clearly underwater with the best swim goggles

Over 90 million Americans swim in pools, lakes and oceans every year, and one-third of that group swims regularly for fitness. No matter where you swim, a good pair of goggles are essential. Goggles help the swimmer see beneath them, while also raising their head above the water line without having to wipe their eyes. Swimming goggles also protect the eyes from chlorine, salt or insects depending on where you are swimming. When it comes to keeping the water out of your eyes and a wide view of what's in front of you, the top choice is the Speedo Vanquisher 2.0 Mirrored Swim Goggle. Fun vs. fitness While swimming goggles can be used for all situations, you may choose different types of goggles depending on your reason for being in the water. If you are relaxing on a summer day in the lake or a public swimming pool, not all of the cutting-edge features of performance goggles may be necessary. If you are completing your regular workout or training for a triathlon, then having extra-tight seals and panoramic lenses may be ideal. Types of swim goggles There are many types of goggles, each with a different purpose. Leisure goggles are the most common and used for recreational swimming as well as swimming laps. They are designed for comfort but still provide a strong seal. Mask goggles cover most of your face and have a very tight seal. They are excellent for being able to look around at your surroundings (similar to snorkeling), but provide too much drag to be used for fitness swimming. Performance goggles are smaller with less cushion around the seal. They are used by professional athletes to reduce the amount of drag they face in the water. A substyle in this category are Swedish goggles, which are designed to cover the eye only and typically don't last long. Most manufacturers also produce goggles to fit children. Lens types There are different types of lenses to choose from for most goggles. Clear goggles are best for indoor swimming or during cloudy conditions. Mirrored goggles are best for sunny days. You can get tinted lenses, which moderately protect against the sun, polarized lenses which provide significant sun protection, or you can even get transition lenses that change according to the amount of light in the swimming area. Comfortable but tight fit One of the most important aspects of swimming goggles is the ability to keep water out of your eyes without being so tight that they make your face hurt. The combination of seals, head straps and nose clips will make up your overall comfort. You want all of them to be snug, but not so tight that it's painful. Gaskets Most leisure goggles come with either silicone, rubber or foam gaskets. These help protect the skin while a seal is formed against the water. You may need to test different materials before finding the one right for you. Racing goggles typically do not have any gaskets. Antifog coating Swimming goggles with an antifog coating help keep the goggles from becoming blurry while you swim, which often requires rinsing them out. Unfortunately, this coating will wear out over time, even with higher-priced goggles. The best way to keep the coating intact is to take care of your goggles according to the manufacturer's recommendations. Swim goggles cost as little as $10-$20 for basic and children's models, while those with adjustable straps and antifog coating are priced between $20-$50. High-performance goggles with transition lenses or prescription lenses can cost over $50. What if I need prescription goggles? A. There are prescription goggles available for people who wear glasses and prefer to keep the ability to see clearly while underwater. Why do my goggles keep fogging up? A. Even antifog goggles can get partially blurry with too much condensation. Over time, the antifog coating will wear off. There are some spray-on antifog products available. Why do my goggles keep leaking? A. It is likely that a gasket in the seal is wearing out due to exposure to chlorine or just long-term use. You should also make sure the goggles haven't been bent from improper storage. Another reason, which seems counterintuitive, is that you may have the goggles on too tightly. Overly restricted goggles can actually lead to water getting inside the lenses. Top swim goggles Speedo Vanquisher 2.0 Mirrored Swim Goggle What you need to know: For swimming in bright sunshine, these goggles set the standard with mirrored lenses. What you'll love: In addition to panoramic minimal-glare lenses, these goggles have cushioned silicone seals that keep water out and an adjustable head strap. Different-sized nose clips are included for maximizing overall fit. What you should consider: The mirrored lenses can make swimming difficult indoors or at night. Top swim goggles for the money ActivAqua Wide View Swimming Goggles What you need to know: These wide-lens goggles have unique design features that help them stay in place and last for a long time. What you'll love: The wide lenses are UV-plated and antifog-plated and come with double silicone seals. A one-snap buckle strap is easy to adjust, even while swimming. The goggles come with a protective case that drains quickly. What you should consider: These goggles are easily adjusted everywhere except the nosepiece. Worth checking out Aqua Sphere Kayenne Swim Goggles What you need to know: These multi-feature goggles are ideal for swimmers of all ages and abilities. What you'll love: Patented curve technology creates a 180-degree view. UV-protected and antifog clear lenses allow natural sunlight. Quick-fit straps and a stabilizing nose piece make for a tight, yet comfortable fit. What you should consider: There have been some reports of the lenses scratching. BestReviews spends thousands of hours researching, analyzing and testing products to recommend the best picks for most consumers. BestReviews and its newspaper partners may earn a commission if you purchase a product through one of our links. Distributed by Tribune Content Agency, LLC.

Vietnam aches for its MIAs. Will America stop funding science to identify them?
Vietnam aches for its MIAs. Will America stop funding science to identify them?

Boston Globe

time2 hours ago

  • Boston Globe

Vietnam aches for its MIAs. Will America stop funding science to identify them?

The search for around 2,600 missing Americans from the Vietnam War has been a first-order issue for Washington and Hanoi ever since the conflict ended. But on that humid June afternoon in northern Vietnam, grave diggers with doctorates were gathering the bones of Vietnam's own missing warriors, whose ranks exceed 1 million, with an urgency and reverence befitting a task long overdue. The scientists were there to advance a recent breakthrough by putting it to use. A few months earlier, they and their partners — including the International Commission on Missing Persons, in The Hague — had figured out the chemistry and computing required to identify remains as badly degraded as those often found in Vietnam's acidic, tropical soil. For the first time, tiny snips of DNA taken from bones up to 70 years old could be used to link the country's fallen soldiers to distant relatives, unlocking lost truths and deeper healing. Families from Vietnam's north and south, their anguish still festering 50 years after the war ended, could find reconciliation in graves where their war dead lie together. Americans still unaccounted for might be found, too, as Vietnam's identification efforts expanded. Methods honed locally could also extend far beyond Vietnam, to help identify those lost to wildfires, typhoons, or other natural disasters worldwide. Advertisement 'Groundbreaking,' said Tim McMahon, director of DNA operations for the US Defense Department. That's how he described the new methods of accounting for the lost, adding: 'It's the next jump in identification.' Advertisement One thing that DNA analysis requires, however, is practice. Repetition at scale improves technique. But for Vietnam and the world, the opportunity that comes with the largest human identification project on the planet is now being threatened by the Trump administration's hostility toward foreign aid. The five-year grant from the United States that had sustained Vietnam's DNA project — paying for sequencing machines and collaborations with the U.S. military and the International Commission on Missing Persons — was suspended with the dismantling of the US Agency for International Development in January. The restored money that's left runs out in September. Before the disruptions, the scientists doing exhumations said they had aimed to identify 1,000 Vietnamese MIAs by July 11, the 30th anniversary of normalized US-Vietnam relations. That, they believed, would prove what former enemies could accomplish by pursuing closure through science. Now they are hoping for one. Thousands of miles from Washington, in Ho Chi Minh City, Vu Thi Ninh Thuy, 42, shared a common Vietnamese war story. A parade marking the 50th anniversary of the end of the conflict had just finished. As graying veterans strolled past the hotel where US generals once briefed reporters on daily body counts, she brought up her uncle, who vanished while fighting the Americans in 1974. Her eyes darting with emotion, she recounted how her childhood had been filled with exploratory trips south and north to look for him. Her family questioned his comrades. They visited local officials and eventually found a psychic who directed them, incorrectly, to a location not far from where she stood on that April morning. Advertisement 'We all feel restless until we can find their remains,' she said. 'Everyone who is Vietnamese wants to bring their loved ones closer to home.' Modern psychology teaches that 'ambiguous loss' — where death remains unverified and without resolution — freezes the grieving process, leading to chronic sorrow. In Vietnam, the pain is compounded by ancient beliefs. The country's common practice of ancestor worship, with offerings left at graves and shrines, dictates that if the dead aren't interred with other ancestors, the person's soul wanders homeless and hungry. Burying and honoring the dead is considered an obligation of the living. Vietnam's official efforts to account for those killed in the war have often been haphazard and hampered by bureaucracy. The remains of at least 300,000 fighters for North Vietnam have been found but not identified. In 2014, the Vietnamese government took a major step toward addressing those shortcomings, announcing that it would invest $25 million in a DNA identification project. A new lab opened on the outskirts of Hanoi in 2019. A year later, the International Commission on Missing Persons came on board. The project expanded with $7.4 million from USAID, awarded over five years, a fraction of what is spent annually to find and identify missing Americans. Experts such as Thomas Parsons have tried to fill gaps in the effort. Wiry and lean, with a frame easily lost in a lab coat, Parsons is a globally recognized authority on forensic genetics and the international commission's lead scientist in Vietnam. Advertisement In March, at the lab near Hanoi, he resembled a mountain climber with no mountain to climb. On a table, a NextSeq 1000, a 'high-throughput' sequencing system delivered in November at a cost of about $220,000, sat idle. It was one of many sophisticated machines covered in plastic after USAID's elimination. Parsons and his Vietnamese colleagues stressed that US foreign aid was not a handout, but rather a way to train Vietnam's researchers for an ambitious task using new genetic methods and technologies. 'We've already achieved a lot,' said Tran Trung Thanh, a molecular biologist and the lab's deputy director. 'We need more time to apply it in practice.' The main breakthrough occurred a few months before Donald Trump's inauguration, with 23 Vietnamese bone samples degraded by age and tropical conditions. Using chemical solutions and high-tech analysis, scientists from the international commission found that 70 percent of the samples generated DNA profiles capable of being matched to a parent or child. Several samples generated enough genetic material to connect with a single great-great-grandchild or even a first cousin's child or parent. Before last year, 9 of every 10 Vietnamese bone samples yielded nothing identifiable. Since President Clinton announced the restoration of diplomatic relations 30 years ago, Vietnam has handed over more than 1,000 sets of American remains. Ambassador Marc Knapper, the son of a Vietnam veteran, has lobbied behind the scenes for the United States to continue supporting Vietnam's MIA program. The International Commission on Missing Persons also wrote to Secretary of State Marco Rubio asking that funding be restored. In March, the project received a partial reprieve: US officials told scientists that they would receive the money allotted through the fiscal year, which ends Sept. 30. Advertisement A State Department spokesperson said that maintaining 'the right mix of programs to support US national security and other core national interests of the United States requires an agile approach.' Instead of requesting another five-year grant, the International Commission on Missing Persons has requested $3 million from the United States to keep the project going for 12 to 18 months. 'If we don't receive funding beyond September,' Kathryne Bomberger, the commission's director general, said in an interview, 'the program will probably end.' This article originally appeared in

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