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23 minutes ago
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FibroBiologics Files Patent for Methods of Generating Multipotent Cells from Donor Tissue for Clinical Applications
HOUSTON, July 28, 2025 (GLOBE NEWSWIRE) -- FibroBiologics, Inc. (Nasdaq: FBLG) ('FibroBiologics'), a clinical-stage biotechnology company with 275+ patents issued and pending with a focus on the development of therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials, announced the filing of a patent application with the United States Patent and Trademark Office covering methods of generating multipotent cells from fibroblasts found in donor tissue for clinical applications. Multipotency refers to a flexible cellular state in which a cell has the potential to differentiate into multiple specialized cell types, depending on the environmental conditions or stimuli it encounters. While stem cells have garnered the most attention on being multipotent, fibroblasts are also considered multipotent and can be directly differentiated into many cell types including chondrocytes, osteocytes, hepatocytes and cardiomyocytes. This patent application broadly relates to methods for generating multipotent cells directly from fibroblasts found in human donor tissues. 'This method provides us with the ability to obtain larger quantities of stable and easily scalable multipotent cells from donor-derived fibroblasts for use in clinical applications,' said Hamid Khoja, Ph.D., Chief Scientific Officer of FibroBiologics. 'Multipotent fibroblasts also show enhanced ability to form 3D spheroid structures, further expanding their potential across a range of therapeutic and drug development areas.' Pete O'Heeron, Founder and Chief Executive Officer of FibroBiologics, said, 'By enabling the generation of stable, multipotent cells directly from donor tissue, this innovation addresses long-standing challenges in the field and opens new possibilities for scalable, regenerative treatments.' For more information, please visit FibroBiologics' website or email FibroBiologics at info@ Cautionary Statement Regarding Forward-Looking Statements This communication contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995. Forward-looking statements include information concerning the potential of multipotent fibroblasts across a range of therapeutic and drug development areas and new possibilities for scalable, regenerative treatments. These forward-looking statements are based on FibroBiologics' management's current expectations, estimates, projections and beliefs, as well as a number of assumptions concerning future events. These forward-looking statements are not guarantees of future performance, conditions or results, and involve a number of known and unknown risks, uncertainties, assumptions and other important factors, many of which are outside FibroBiologics' management's control, that could cause actual results to differ materially from the results discussed in the forward-looking statements, including those set forth under the caption "Risk Factors" and elsewhere in FibroBiologics' annual, quarterly and current reports (i.e., Form 10-K, Form 10-Q and Form 8-K) as filed or furnished with the SEC and any subsequent public filings. Copies are available on the SEC's website, These risks, uncertainties, assumptions and other important factors include, but are not limited to: (a) risks related to FibroBiologics' liquidity and its ability to maintain capital resources sufficient to conduct its business; (b) expectations regarding the initiation, progress and expected results of our R&D efforts and preclinical studies; (c) the unpredictable relationship between R&D and preclinical results and clinical study results; and (d) the ability of FibroBiologics to successfully prosecute its patent applications. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and FibroBiologics assumes no obligation and, except as required by law, does not intend to update, or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. FibroBiologics gives no assurance that it will achieve its expectations. About FibroBiologics Based in Houston, FibroBiologics is a clinical-stage biotechnology company developing a pipeline of treatments and seeking potential cures for chronic diseases using fibroblast cells and fibroblast-derived materials. FibroBiologics holds 275+ US and internationally issued patents/patents pending across various clinical pathways, including wound healing, multiple sclerosis, disc degeneration, psoriasis, orthopedics, human longevity, and cancer. FibroBiologics represents the next generation of medical advancement in cell therapy and tissue regeneration. For more information, visit General Inquiries:info@ Investor Relations:Nic JohnsonRusso Partners(212) 845-4242fibrobiologicsIR@ Media Contact:Liz PhillipsRusso Partners(347) in to access your portfolio
Yahoo
23 minutes ago
- Yahoo
"'Oh, This Is Whole Foods?'": People Share Their Experiences With Very, Very Wealthy Friends, And I'm Genuinely Shocked At How Out Of Touch They Are
Unfortunately, wealth disparity exists in this world. Cough — the Bezos-Sánchez $50 million wedding comes to mind. In r/ask, when someone asked, "Something your rich friends have said that made your jaw drop?", people weighed in on how this exists all around us. And wow, what a peek into a gilded reality. Here's what people had to say: 1."A group of us went to McDonald's, and after he got his cheeseburger, he went back to the counter to ask them to center his cheese." —bunk3rk1ng 2."'I don't get it. What would he need two jobs for?'" —superkow 3."I accidentally found out that what I made in a year, working full time, he made in a month. Yeah, I knew he was wealthy, but that put it into perspective." —Interesting_Day2277 4."I had the 17-year-old daughter of a rich acquaintance visit our city with a few of her friends for spring break. I was helping her check into their hotel (the most expensive one in the city) when she decided she didn't like the suite and wondered if an upgrade was available. Indeed, there was —the penthouse, but it would cost an additional $8k or more. Without batting an eye, she whips out HER CREDIT CARD and says, 'Use this one.' A 17-year-old with a five-digit credit card limit, who didn't need her parents' permission to use it, just blew my mind." —Middle-Luck-997 5."I was a council house kid. I went to school with lots of better-off kids and some rich ones. Some were OK, but some didn't seem to understand, or care, for that matter. What gets me is the calm acceptance. You want a new bicycle? Here, have one. Clothes? Sure, have what you like. A Bang & Olufsen stereo for your room? Here it is, son. Motorbikes, cars, even houses. No problem. Must be nice to have 'stuff,' although some of the parents weren't that interested in their kids from what I could see. A couple of the blokes I've known later in life who came from monied families, reckoned they were basically treated as an inconvenience, and packed off to boarding school as soon as possible." WB / Via —Amplidyne 6."Not friends, but some estranged family I've recently connected with dropped this line: 'We're middle class.' Yet, they own three houses, multiple business ventures, and she does triathlons all over the world. They just extended their vacation in, I think, Guam, because she wanted to adopt two dogs off the street, but couldn't bring them home during their current vacation time due to the pups' health concerns. Completely out of touch. Also, they asked me, 'Why do you guys rent in San Diego when you could just buy a house instead and build up the equity?' Like that's a possibility." —nobeer4you 7."'We'll keep it small, just a few friends over.' It turned out to be a 50-person party with wedding-worthy flowers, an eight-person catering staff, and two live entertainment acts. 12 people I didn't know brought presents for my son." —NightSisterSally 8."'I traveled economy once. Ugh, it was so narrow.'" —shiroandae 9."'How did your parents invest the money they saved for you?' Bro. My parents didn't save money for me. They fed me, clothed me, supported me, and paid for some extracurriculars. I'm grateful. Not all parents have the ability to save as well." —Foreign-Yak-3223 10."One didn't notice an entire family gym membership leaking out of their bank account for a year. They thought they'd canceled it. It was £300 a month." —South-Bank-stroll 11."'We need poor people for society to function.'" —Poulop 12."Their parent's salary equates to my lifetime income." —Intelligent_Way_9450 13."His parents bought him a house near the university because they didn't see the point in paying for a year of rent." —Financial_Change_183 14."A friend from uni gave me a ride in a $50k Mercedes. I said it was a cool car, and he said, 'You should have seen the other one,' but he crashed it. It was a $100k car. Mind you, we were 18 and 19 at the time." —SignalElderberry600 15."A best friend growing up got a full ride to go to college, even though he was filthy rich. Our friend group was talking about student loans, and he chimed in, saying he took out $20k in loans and spent it on shoes and liquor because that's what college is about. We stopped talking." —Cocoononthemoon 16."A woman I worked for recommended a $35 mouthwash to me. It was 1.5 ounces." —chudock74 17."I heard a rich guy say that people don't use the word groceries anymore." —Hister333 "What does he mean?" —PassengerNo2022 18."I went to Whole Foods with my friend, and he said, 'Oh, this is Whole Foods? So, this is where [House Manager Name] goes to get our food!'" —Dull_Wrongdoer_3017 19."On what to do for my 18th birthday, she suggested flying my friends out to another country and renting a private yacht. That would've cost $2,500 for just the tickets and the yacht, plus more, for other expenses like cabs, food, and whatnot." —SoggyDoughnut69 20."'I think my trust fund is around $9 million.' Later that day, he found out it was $23 million. This is a person in their late 30s." —sixjasefive 21."They want to go golfing in the middle of the day, on a weekday." —3rody 22."'I'm not materialistic.'" HBO / Via HBO / Via —Tak-Tik-2 finally, "'I keep spending money and more just shows up in the account.' I almost cried." —ohyesiam1234 I'm crying in pennies. Any wealthy friend stories to share? Let us know in the comments! Note: Responses have been edited for length/clarity. Solve the daily Crossword
Yahoo
23 minutes ago
- Yahoo
Teamsters call UPS driver buyout offer ‘paltry'
UPS is offering delivery drivers voluntary severance packages worth $1,800 per year of service, with a minimum payout of $10,000, according to a recent statement from the company. Drivers have until Thursday to apply for the program, according to an employee memo visible in a TikTok video posted last week by the Teamsters union, which claims the buyout violates the collective bargaining agreement and is urging members not to accept the offer. The video is accompanied by the Elvis Presley song 'Return to Sender' and shows a man tearing up the offer sheet. FreightWaves was able to magnify the image with software tools to read the text, which is fuzzy to a normal viewer. 'UPS Teamsters want secure retirements with hard-earned pensions, not paltry buyouts,' the union said in an X message on Sunday. A driver who spoke on a YouTube video called $1,800 per year of service 'a slap in the face.' UPS (NYSE: UPS) announced the buyout program on July 3 as a follow-on to the largest network reconfiguration in company history, now underway. The strategy, called Network of the Future, calls for the closing of 200 domestic package sortation centers, investment in more automation and consolidation of volumes in more efficient facilities. The integrated parcel logistics giant earlier this year announced plans to eliminate 20,000 front-line positions to better align the workforce with the smaller footprint and a planned 50% downsizing in business from Amazon, its largest customer. A driver with 27 years of experience would receive a $48,600 buyout, according to the internal communication posted by the Teamsters. Applicants will be considered for separation dates between Aug. 31 and Oct. 31, depending on the local needs, UPS said. If the number of applications exceeds eliminated positions, approvals will be granted in order of seniority. Additional applications may be considered for separation dates between Feb. 1 and March 31. The financial package is in addition to earned retirement benefits, including pension and healthcare. Supply Chain Dive first reported on the specifics of the buyout offer. The Teamsters argue the Driver Voluntary Separation Program violates the union contract because it wasn't negotiated and any program that changes the terms of employment, such as compensation and separation, must be bargained with the union. Seniority order for buyouts also requires union approval. And, the union notes, that UPS offered job security guarantees in 2023, as well as promising to elevate more than 20,000 part-time drivers to full-time status. The Teamsters are urging UPS drivers not to accept the buyout terms, likely because they believe they can negotiate a better deal, and also to maintain control over how these types of scenarios are handled, experts said 'This situation with UPS and the Teamsters is a classic example of how even a company's apparent right to manage its resources is limited by the terms of existing agreements. The 'illegality,' according to the union, lies not in the act of downsizing itself, but in the procedure and conditions that violate the current collective bargaining agreement. This is a struggle over who dictates the rules of engagement in the relationship between the company and its union-represented employees,' wrote Dmitriy Karpov, co-founder and CFO of e-commerce technology provider Split Development LLC, on LinkedIn. Satish Jindel, CEO of ShipMatrix, a parcel shipping consultancy and analytics provider, said in an interview, 'UPS is allowed to offer buyouts. Workers can say no. Nothing says they can't make an offer' when market conditions change. He said the Teamsters is lucky UPS backed down from a looming strike in 2023 because it could have become union-free at half the cost by offering those jobs to FedEx and Amazon drivers, who would have eagerly jumped at a $25/hour rate and good benefits. UPS is scheduled to issue second quarter earnings results on Tuesday. Click here for more FreightWaves/American Shipper stories by Eric Kulisch. RELATED READING: UPS to eliminate 20K jobs as Amazon decoupling accelerates UPS drivers to receive buyout offer as company shrinks parcel network The post Teamsters call UPS driver buyout offer 'paltry' appeared first on FreightWaves.
