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Hoping that viruses will go away is not enough – what is needed is continuous vigilance

Hoping that viruses will go away is not enough – what is needed is continuous vigilance

Telegraph2 days ago

In the public debate about pandemics, there is a belief as persistent as it is dangerous: the idea that epidemics end, that viruses – once contained – will disappear like a summer storm.
But virology and epidemiology teach us that viruses do not disappear. Viruses adapt and mutate. They lurk in the folds of health inequalities and gaps in global surveillance.
The latest alarm comes from Sierra Leone, which, after reporting its first two cases of mpox (formerly known as monkeypox) in January and declaring a public health emergency, is now facing a significant expansion of the epidemic.
According to official sources, the country has reported over 3,000 confirmed cases and at least 15 deaths, with infections concentrated particularly in Western Area Urban, Western Area Rural, and Bombali.
National health authorities, assisted by the WHO, Unicef, Africa CDC, and Gavi, have implemented a comprehensive emergency plan: strengthening surveillance, isolating cases, contact tracing, and launching awareness campaigns in schools and rural communities.
As a result, 61,300 doses of the MVA-BN vaccine are expected to arrive in the coming weeks, and hundreds of health workers are being trained on diagnostic, treatment, and prevention protocols.
This outbreak is becoming particularly worrisome due to the high vulnerability of children, who face a mortality risk up to four times higher than adults, especially in conditions of malnutrition or poor hygiene.
On a continental scale, Africa is witnessing a rise in cases, with over 50,000 reported since the beginning of the year and more than 1,700 deaths. A critical factor is the viral clade involved.
While full genomic mapping is still underway, the Africa CDC has reported that clade IIb, which has been associated with faster human-to-human transmission and potentially exponential spread, is likely the dominant strain in Sierra Leone.
Despite Sierra Leone's improved emergency response capacity, gained during the 2014-2016 Ebola outbreak, healthcare infrastructure remains under strain.
Patients often share beds, and clinical recognition delays persist, reflecting systemic pressures that could hamper containment efforts.
Viruses return when the world 'moves on'
Recent history, from Covid-19 to polio, shows that viruses do not 'die out' with a decree or a short-lived vaccination campaign.
Zoonotic viruses, in particular, have an inherent ability to remain in circulation between animal and human hosts, often with different symptomatologies, and to re-emerge under favourable conditions.
When surveillance loosens, when public health is underfunded, when the world 'moves on,' viruses return.
Mpox is emblematic in this regard. For decades considered a virus confined to parts of central Africa, it has found new vectors, new susceptible populations, and new routes of transmission.
Its recent mutations – linked to clade IIb – suggest adaptations to human infection that could make it endemic even in hitherto unaffected areas. Its apparent disappearance in high-income countries after the 2022-2023 wave is illusory: it was not a biological defeat, but a logistical suspension.
Yet there are examples of good health behaviour from which the whole world should draw inspiration.
In Tanzania in 2023, a small outbreak of Marburg virus – one of the world's deadliest pathogens, belonging to the same family as Ebola – was contained through a timely, transparent and coordinated response.
The Tanzanian Ministry of Health quickly put in place measures for contact tracing, case isolation, effective public communication and cooperation with WHO.
Similar efficiency was demonstrated in Rwanda, where preparedness for potential Marburg cases became a pillar of public health strategy, despite the fact that no outbreaks had occurred.
Both countries invested in decentralised surveillance systems, widespread health training, and integration of human and veterinary medicine-embodying the concept of 'One Health'.
These examples show that prevention is not a luxury of rich countries, but a strategic choice that is possible everywhere if supported by political will and real, non-paternalistic international cooperation.
The new mpox outbreak in Sierra Leone must be interpreted in light of a fundamental fact: the transmissibility of viruses knows no geopolitical boundaries.
Emerging diseases are now more than ever a global health security issue. A delay in diagnosis in Freetown can trigger an infection in Paris, London or Toronto within days.
Yet funding for surveillance and diagnostic laboratories remains concentrated in a few areas. Large regions of Africa, Asia, and Latin America lack sentinel systems capable of detecting new threats in real time. Where the first patient is not identified, the virus has already won the first round.
Continuing to hope that 'it won't happen here,' or that 'this time it is just a small outbreak,' is a mistake we have already paid dearly for.
The mpox emergency in Sierra Leone is not yet a pandemic, but it is already an opportunity: to invest, to coordinate, to train.
Epidemiological surveillance must become a structural and continuous investment, not an emergency response. We need a global network that not only responds, but predicts. One that recognises the global potential in seemingly minor outbreaks, and that funds local health systems not just to treat, but to monitor and to anticipate.
Hoping that viruses will disappear is an understandable but naive wish. The only scientifically sound response is permanent, equitable, multilevel surveillance. We can no longer afford to ignore weak signals. Every contained outbreak is a shared victory; every ignored outbreak is a global defeat waiting to happen.
Francesco Branda is an Adjunct professor at the Faculty of Medicine and Surgery at Campus Bio-Medico University of Rome
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Many forget the damage done by diseases like whooping cough, measles and rubella. Not these families
Many forget the damage done by diseases like whooping cough, measles and rubella. Not these families

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Many forget the damage done by diseases like whooping cough, measles and rubella. Not these families

In the time before widespread vaccination, death often came early. Devastating infectious diseases ran rampant in America, killing millions of children and leaving others with lifelong health problems. These illnesses were the main reason why nearly one in five children in 1900 never made it to their fifth birthday. Over the next century, vaccines virtually wiped out long-feared scourges like polio and measles and drastically reduced the toll of many others. Today, however, some preventable, contagious diseases are making a comeback as vaccine hesitancy pushes immunization rates down. And well-established vaccines are facing suspicion even from public officials, with Robert F. Kennedy Jr., a longtime anti-vaccine activist, running the federal health department. 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Getting rubella while pregnant shaped two lives With a mother's practiced, guiding hand, 80-year-old Janith Farnham helped steer her 60-year-old daughter's walker through a Sioux Falls art center. They stopped at a painting of a cow wearing a hat. Janith pointed to the hat, then to her daughter Jacque's Minnesota Twins cap. Jacque did the same. 'That's so funny!' Janith said, leaning in close to say the words in sign language too. Jacque was born with congenital rubella syndrome, which can cause a host of issues including hearing impairment, eye problems, heart defects and intellectual disabilities. There was no vaccine against rubella back then, and Janith contracted the viral illness very early in the pregnancy, when she had up to a 90% chance of giving birth to a baby with the syndrome. Janith recalled knowing 'things weren't right' almost immediately. The baby wouldn't respond to sounds or look at anything but lights. She didn't like to be held close. Her tiny heart sounded like it purred – evidence of a problem that required surgery at four months old. Janith did all she could to help Jacque thrive, sending her to the Colorado School for the Deaf and the Blind and using skills she honed as a special education teacher. She and other parents of children with the syndrome shared insights in a support group. Meanwhile, the condition kept taking its toll. As a young adult, Jacque developed diabetes, glaucoma and autistic behaviors. Eventually, arthritis set in. Today, Jacque lives in an adult residential home a short drive from Janith's place. Above her bed is a net overflowing with stuffed animals. On a headboard shelf are photo books Janith created, filled with memories like birthday parties and trips to Mount Rushmore. Jacque's days typically begin with an insulin shot and breakfast before she heads off to a day program. She gets together with her mom four or five days a week. They often hang out at Janith's townhome, where Jacque has another bedroom decorated with her own artwork and quilts Janith sewed for her. Jacque loves playing with Janith's dog, watching sports on television and looking up things on her iPad. Janith marvels at Jacque's sense of humor, gratefulness, curiosity and affectionate nature despite all she's endured. Jacque is generous with kisses and often signs 'double I love yous' to family, friends and new people she meets. 'When you live through so much pain and so much difficulty and so much challenge, sometimes I think: Well, she doesn't know any different,' Janith said. Given what her family has been through, Janith believes younger people are being selfish if they choose not to get their children the MMR shot against measles, mumps and rubella. 'It's more than frustrating. I mean, I get angry inside,' she said. 'I know what can happen, and I just don't want anybody else to go through this.' Delaying the measles vaccine can be deadly More than half a century has passed, but Patricia Tobin still vividly recalls getting home from work, opening the car door and hearing her mother scream. Inside the house, her little sister Karen lay unconscious on the bathroom floor. It was 1970, and Karen was 6. She'd contracted measles shortly after Easter. While an early vaccine was available, it wasn't required for school in Miami where they lived. Karen's doctor discussed immunizing the first grader, but their mother didn't share his sense of urgency. 'It's not that she was against it," Tobin said. "She just thought there was time.' Then came a measles outbreak. Karen – who Tobin described as a 'very endearing, sweet child' who would walk around the house singing – quickly became very sick. The afternoon she collapsed in the bathroom, Tobin, then 19, called the ambulance. Karen never regained consciousness. 'She immediately went into a coma and she died of encephalitis,' said Tobin, who stayed at her bedside in the hospital. 'We never did get to speak to her again.' Today, all states require that children get certain vaccines to attend school. But a growing number of people are making use of exemptions allowed for medical, religious or philosophical reasons. Vanderbilt's Schaffner said fading memories of measles outbreaks were exacerbated by a fraudulent, retracted study claiming a link between the MMR shot and autism. The result? Most states are below the 95% vaccination threshold for kindergartners — the level needed to protect communities against measles outbreaks. 'I'm very upset by how cavalier people are being about the measles,' Tobin said. 'I don't think that they realize how destructive this is.' Polio changed a life twice One of Lora Duguay's earliest memories is lying in a hospital isolation ward with her feverish, paralyzed body packed in ice. She was three years old. 'I could only see my parents through a glass window. They were crying and I was screaming my head off,' said Duguay, 68. 'They told my parents I would never walk or move again.' It was 1959 and Duguay, of Clearwater, Florida, had polio. It mostly preyed on children and was one of the most feared diseases in the U.S., experts say, causing some terrified parents to keep children inside and avoid crowds during epidemics. Given polio's visibility, the vaccine against it was widely and enthusiastically welcomed. But the early vaccine that Duguay got was only about 80% to 90% effective. Not enough people were vaccinated or protected yet to stop the virus from spreading. Duguay initially defied her doctors. After intensive treatment and physical therapy, she walked and even ran – albeit with a limp. She got married, raised a son and worked as a medical transcriptionist. But in her early 40s, she noticed she couldn't walk as far as she used to. A doctor confirmed she was in the early stages of post-polio syndrome, a neuromuscular disorder that worsens over time. One morning, she tried to stand up and couldn't move her left leg. After two weeks in a rehab facility, she started painting to stay busy. Eventually, she joined arts organizations and began showing and selling her work. Art "gives me a sense of purpose,' she said. These days, she can't hold up her arms long enough to create big oil paintings at an easel. So she pulls her wheelchair up to an electric desk to paint on smaller surfaces like stones and petrified wood. The disease that changed her life twice is no longer a problem in the U.S. So many children get the vaccine — which is far more effective than earlier versions — that it doesn't just protect individuals but it prevents occasional cases that arrive in the U.S. from spreading further. ' Herd immunity " keeps everyone safe by preventing outbreaks that can sicken the vulnerable. After whooping cough struck, 'she was gone' Every night, Katie Van Tornhout rubs a plaster cast of a tiny foot, a vestige of the daughter she lost to whooping cough at just 37 days old. Callie Grace was born on Christmas Eve 2009 after Van Tornhout and her husband tried five years for a baby. She was six weeks early but healthy. 'She loved to have her feet rubbed," said the 40-year-old Lakeville, Indiana mom. "She was this perfect baby.' When Callie turned a month old, she began to cough, prompting a visit to the doctor, who didn't suspect anything serious. By the following night, Callie was doing worse. They went back. In the waiting room, she became blue and limp in Van Tornhout's arms. The medical team whisked her away and beat lightly on her back. She took a deep breath and giggled. Though the giggle was reassuring, the Van Tornhouts went to the ER, where Callie's skin turned blue again. For a while, medical treatment helped. 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She also shares her story with people she meets, like a pregnant customer who came into the restaurant her family ran saying she didn't want to immunize her baby. She later returned with her vaccinated four-month-old. 'It's up to us as adults to protect our children – like, that's what a parent's job is,' Van Tornhout said. 'I watched my daughter die from something that was preventable … You don't want to walk in my shoes.' ____ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

Takeaways from interviews with families forever changed by diseases that vaccines can prevent
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In the time before widespread vaccination, devastating infectious diseases ran rampant in America, killing millions of children and leaving others with lifelong health problems. Over the next century, vaccines virtually wiped out long-feared scourges like polio and measles and drastically reduced the toll of many others. Today, however, some preventable, contagious diseases are making a comeback as vaccine hesitancy pushes immunization rates down. And well-established vaccines are facing suspicion even from public officials, with Robert F. Kennedy Jr., a longtime anti-vaccine activist, running the federal health department. 'This concern, this hesitancy, these questions about vaccines are a consequence of the great success of the vaccines – because they eliminated the diseases,' said Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center. 'If you're not familiar with the disease, you don't respect or even fear it. And therefore you don't value the vaccine.' Anti-vaccine activists even portray the shots as a threat, focusing on the rare risk of side effects while ignoring the far larger risks posed by the diseases themselves — and years of real-world data that experts say proves the vaccines are safe. Some Americans know the reality of vaccine-preventable diseases all too well. Here are takeaways from interviews with a few of them by The Associated Press. Getting a disease while pregnant can change two lives. Janith Farnham has helped shepherd her daughter Jacque through life for decades. Jacque, 60, was born with congenital rubella syndrome, which resulted in hearing, eye and heart problems at birth. There was no vaccine against rubella back then, and Janith contracted it in early pregnancy. Though Janith, 80, did all she could to help Jacque thrive, the condition took its toll. Jacque eventually developed diabetes, glaucoma, autistic behaviors and arthritis. Today, Jacque lives in an adult residential home and gets together with Janith four or five days a week. Janith marvels at Jacque's sense of humor and affectionate nature despite all she's endured. Jacque is generous with kisses and often signs 'double I love yous,' even to new people she meets. Given what her family has been through, Janith finds it 'more than frustrating' when people choose not to get children the MMR shot against measles, mumps and rubella. 'I know what can happen,' she said. 'I just don't want anybody else to go through this.' Delaying a vaccine can be deadly. More than half a century has passed, but Patricia Tobin still vividly recalls seeing her little sister Karen unconscious on the bathroom floor. It was 1970, Karen was 6, and she had measles. The vaccine against it wasn't required for school in Miami where they lived. Though Karen's doctor discussed immunizing the first grader, their mother didn't share his sense of urgency. 'It's not that she was against it,' Tobin said. 'She just thought there was time.' Then came a measles outbreak. After she collapsed in the bathroom, Karen never regained consciousness. She died of encephalitis. 'We never did get to speak to her again,' Tobin said. Today, all states require that children get certain vaccines to attend school. But a growing number of people are making use of exemptions. Vanderbilt's Schaffner said fading memories of measles outbreaks were exacerbated by a fraudulent, retracted study claiming a link between the MMR shot and autism. The result? Most states are below the 95% vaccination threshold for kindergartners — the level needed to protect communities against measles outbreaks. Preventable diseases can have long-term effects. One of Lora Duguay's earliest memories is lying in a hospital isolation ward with her feverish, paralyzed body packed in ice. She was three years old. It was 1959 and Duguay, of Clearwater, Florida, had polio. 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When people aren't vaccinated, the vulnerable remain at risk. Every night, Katie Van Tornhout rubs a plaster cast of a tiny foot, a vestige of the daughter she lost to whooping cough at just 37 days old. Callie Grace was born on Christmas Eve 2009. When she turned a month old, she began having symptoms of pertussis, or whooping cough. She was too young for the Tdap vaccine against it and was exposed to someone who hadn't gotten their booster shot. At the hospital, Van Tornhout recalled, the medical staff frantically tried to save her, but 'within minutes, she was gone.' Today, Callie remains part of her family's life, and Van Tornhout shares the story with others as she advocates for vaccination. 'It's up to us as adults to protect our children – like, that's what a parent's job is,' Van Tornhout said. 'I watched my daughter die from something that was preventable … You don't want to walk in my shoes.' ____ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

Update on Guildford paddling pool plagued by problems
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BBC News

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Update on Guildford paddling pool plagued by problems

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