FDA appoints George Tidmarsh as top drug regulator
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The Independent
2 hours ago
- The Independent
New research explains why wrinkles develop with age
Scientists at Binghamton University have experimentally shown that skin wrinkles as it ages due to a process where it stretches laterally and then contracts, forming creases. Associate Professor Guy German explained that the skin's mechanical properties degrade with age, causing increased lateral stretching driven by inherent forces within the skin. The research involved using a low-force tensometer on skin samples from individuals aged 16 to 91, providing experimental evidence for previously theoretical models of skin aging. This new finding complements existing knowledge that genetics, disease, sun exposure, and repeated muscle movements also contribute to the formation of wrinkles. Published in the Journal of the Mechanical Behavior of Biomedical Materials, the study did not investigate methods to prevent these newly identified forces, though external factors like sun damage are acknowledged.
Daily Mail
3 hours ago
- Daily Mail
EXCLUSIVE Layton and Whitney spent years planning their dream honeymoon in Mexico. But then one small symptom quickly turned paradise into panic
A newlywed has spent weeks in an intensive care unit in Mexico after he began experiencing intense stomach pains on his honeymoon. Layton, 29, and Whitney McCann, 30, were married on April 5 and spent months planning the honeymoon of their dreams in the United States and Mexico. Mr McCann, a schoolteacher, and Mrs McCann, a hair salon owner, left Geelong, Victoria, and flew to Playa Del Carmen after two weeks in the US. However, just days after arriving in the coastal resort town, Mr McCann began experiencing intense abdominal pain. Mrs McCann's sister, Bronte Holland, said the situation escalated quickly. 'The hotel they were staying at had a doctor so they called the doctor into the room,' she told Daily Mail Australia. 'He gave Layton something and then left. My sister called the doctor back after 10 minutes because he was really not well. 'They sent him to hospital and he's been there now for nearly two weeks.' Tests revealed Mr McCann had contracted an infection that led to pancreatitis and he was rushed to the closest intensive care unit. His mother and mother-in-law arrived in Mexico on Sunday, with Mr McCann put in an induced coma and on a ventilator the following day. 'They're not sure what caused it,' Ms Holland said. 'It could've been the food or the alcohol that he was having on his honeymoon but something has triggered this infection. 'The pancreas was all inflamed and it started to die, so they've put him in a coma.' The family, who are facing a language barrier, considered medically evacuating Mr McCann home to Australia, but he is currently too unstable to travel. 'Layton's whole body swelled up, all his face was swollen,' Ms Holland said. 'I'm a nurse and, from what my sister's telling me, they're doing a really good job taking care of him. They've been checking his bloods, doing CT scans every day. 'My sister's travel insurance also set up a doctor in Australia she can liaise with. Everything's just extra stressful because of the language barrier.' Mr McCann's deterioration has left his family members rattled. 'He's an avid cricket player. He's part of the North Geelong cricket club and he runs every day,' Ms Holland said. 'He's very physically active and a healthy young bloke.' While the couple's medical bills are being covered by their travel insurance, they still face several ongoing costs. On top of accommodation and additional flights, Mrs McCann runs her own business and loses income each day she misses work. Ms Holland has created a GoFundMe to help relieve some of the financial pressure. 'Everyone's stressed and everyone's a mess,' she said. 'It's just so sad, they only just got married. They should be having the time of their lives on their honeymoon, this is not how it's supposed to go.
Reuters
5 hours ago
- Reuters
Roche pauses shipments of Elevidys gene therapy outside US
July 22 (Reuters) - Roche Holding AG (ROG.S), opens new tab said on Tuesday it has paused all shipments of muscular disorder gene therapy Elevidys outside the U.S., echoing a similar decision by U.S. partner Sarepta Therapeutics (SRPT.O), opens new tab on Tuesday. The Swiss drugmaker said the pause, effective Tuesday, applies to new orders of Elevidys in countries outside the U.S. that reference the Food and Drug Administration as the basis for their local approval. The pause is voluntary and temporary, and applies to all patients with Duchenne muscular dystrophy regardless of their ability to walk, Roche said in an emailed statement. Roche acquired the commercial rights to Sarepta's Elevidys outside the United States in 2019. Bloomberg News first reported the development.
