Weight loss jabs won't help you shift the pounds if you're still doing these things
With Mounjaro being rolled out at GPs down south, experts have listed the reasons why people getting the jabs may still not lose weight
As the NHS down south begins rolling out weight-loss injections through GPs, demand is expected to rise sharply. However, with only around 220,000 patients eligible over the next three years, access may not be as easy as many expect.
One particular injectable drawing significant notice and media coverage is Mounjaro, or Tirzepatide, to give it its medical name, initially developed for the management of type 2 diabetes.
The medication has been licensed in the UK for obesity treatment since November 2024, earning acclaim for its effectiveness in facilitating substantial weight loss. Other injectable treatments include Wegovy and Nevolat.
"While Mounjaro is an effective medication for weight loss, it's normal to encounter a plateau at some point," Dr. Crystal Wyllie at ZAVA explained.
"With the NHS rollout still limited, many people won't qualify straight away, so understanding your full range of options is crucial.... working closely with your doctor is key to finding the safest and most personalised approach."
As Mounjaro becomes more widely available, experts at ZAVA want to remind users what to expect, why it might not always work as expected, and how to avoid common setbacks.
Incorrect medication use or dosage
Mounjaro's effectiveness often increases as you move up the dosage ladder, ZAVA healthcare providers advise. The medication is typically titrated slowly to reduce side effects, eventually reaching maintenance doses of up to 15mg per week.
If you're still on a lower dose or haven't advanced as recommended, your weight loss may be limited. Consistency is crucial. Skipping doses, delaying titration, or not following your provider's schedule can reduce the medication's impact.
Many people don't feel the full effect until 8–12 weeks in, so patience and adherence are key. You should give Mounjaro at least three months before judging its effectiveness.
If you're experiencing side effects, it's absolutely fine to remain at a lower dose for longer. Step up more slowly if you're not tolerating side effects well, there's no need to push through discomfort.
You can always increase the dose later once your body has adjusted. Comfort and tolerability are just as important as consistency for long-term success.
Poor diet and lack of exercise
Weight loss jabs don't override the fundamental rule of weight loss - you must burn more calories than you consume. Even with a smaller appetite, eating more than your body needs will still cause progress to stall.
Healthy diet tips:
Be strict with calorie tracking until portion control becomes second nature
Aim for a calorie daily deficit to lose weight steadily
Prioritise whole foods over high-sugar, high-fat processed options
Follow a diet tailored to your needs, and explore healthy recipe ideas to stay on track
Stay hydrated and limit alcohol
Stress and sleep issues
Chronic stress and poor sleep are major weight loss blockers. Stress increases cortisol, a hormone linked to fat retention, especially around the abdomen.
Sleep deprivation increases ghrelin (hunger hormone) and decreases leptin (fullness hormone), making you more likely to overeat and less likely to move.
You're also more impulsive and less motivated when sleep-deprived, making it harder to stick to your diet and exercise routine. Prioritise stress management techniques (like mindfulness or journaling), and aim for 7-9 hours of sleep per night.
Health conditions and medications
Medical issues such as PCOS, diabetes, hypothyroidism, or insulin resistance can all interfere with weight loss. Similarly, certain medications (like antidepressants or steroids) may cause weight gain or inhibit fat loss.
If weight loss stalls despite doing everything right, consult your GP to rule out or address any underlying conditions. If you have a known medical condition, keep on top of your routine reviews and inform your GP or specialist about any weight loss treatments you're using. Follow-up helps ensure your treatment plan remains safe and effective.
Unrealistic expectations
Weight loss is a long-term process. Initial drops (often water weight) can be misleading. Progress will slow, and that's okay. Avoid comparing yourself to others or obsessively checking the scale.
Focus on consistency, not speed. Your journey is unique, and sustainable weight loss takes time.
Lack of support
Motivation by itself often isn't enough. Without support from those who understand your goals, the journey can feel lonely and overwhelming. Lean on friends and family who encourage you.
Join online communities or local support groups, including NHS-recommended programs.
Consider working with a dietitian or coach for personalised guidance and accountability Before beginning any weight loss treatment, please consult your GP or healthcare professional. These treatments may not be suitable for everyone.
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