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Next year's Eastern Zonal Council meeting to be held in Puri: Odisha CM
Next year's Eastern Zonal Council meeting to be held in Puri: Odisha CM

India Gazette

time5 days ago

  • Politics
  • India Gazette

Next year's Eastern Zonal Council meeting to be held in Puri: Odisha CM

Bhubaneswar (Odisha) [India], July 11 (ANI): Next year the 28th Eastern Zonal Council meeting will be held in Odisha's Puri, Chief Minister Mohan Charan Majhi said. Majhi who returned to Bhubaneswar after attending the 27th Eastern Zonal Council meeting held in Ranchi on Thursday said this in a statement to mediapersons at the airport. The Chief Minister said that he had proposed to hold this meeting in Odisha next year and this was accepted by Union Minister Amit Shah and all other members. It was announced in the meeting that it will be held in Puri. The Chief Minister said that the 27th Eastern Zonal Council meeting covered Jharkhand, Bihar, West Bengal, and Odisha had successfully concluded. In particular, discussions were held on how to accelerate the social and economic development of the region and how to reach the unreached areas with the schemes. The role of all these states is important in fulfilling the goals of Prime Minister Narendra Modi's developed India. The meeting focused on various successful schemes and programs to achieve the goals of developed India for the betterment of every section of society. The Chief Minister said that the Union Home Minister Amit Shah has emphasised the need to completely eliminate Naxal activities from the country by March 31, 2026, and various ways to solve the Naxal problem were also discussed in this meeting. So far, considerable success has been achieved in this regard. The meeting thanked the Union Minister for the focused steps he is taking to solve this problem. The meeting also focused on ensuring that the benefits of the Ayushman Bharat scheme reach everyone (Saturation Stage) and that all beneficiaries get their benefits. He said that he also briefed the meeting about the success of various schemes of Odisha. Information was given on various programs such as women empowerment, success of Shri Anna Yojana, success of Ayushman Bharat Yojana, etc. Chief Minister Majhi said that there is a need for further improvement in the banking services sector in Odisha. Banking services have not reached many areas. Therefore, he said that he has proposed in the meeting to take appropriate steps to provide banking services to more areas of Odisha. Deputy Chief Minister Parvathi Parida and Health and Family Welfare Minister Mukesh Mahaling also attended the meeting. Many MLAs were present at the airport and gave the Chief Minister a grand welcome after he returned from Ranchi. (ANI)

Odisha: Commuters face inconvenience as drivers' protest enters day 4
Odisha: Commuters face inconvenience as drivers' protest enters day 4

India Gazette

time5 days ago

  • Politics
  • India Gazette

Odisha: Commuters face inconvenience as drivers' protest enters day 4

Bhubaneswar (Odisha) [India], July 11 (ANI): Commuters in Odisha face inconvenience as transport services are disrupted due to the Odisha Driver Mahasangh entering its fourth day. The drivers of private buses, trucks, taxis and commercial vehicles have joined a strike since Tuesday over various demands, including the formation of a drivers' welfare fund, pension benefits after 60 years, legal protection from public hostility and designated parking lots and rest rooms with basic facilities every 100 km. Vice-President of Odisha Drivers Federation Santosh Sahu on Thursday said that the association demands government assistance to drivers in case of post-accident violence and inclusion of auto drivers in the Drivers Union. 'Today is the third day of our strike, and we will continue the strike till our demands are met. Our demands are parking and toilet facilities, government assistance to drivers in case of post-accident violence, inclusion of auto drivers in the Drivers Union, and 70% of the drivers should be from the state... There has been no clear assurance from the government on these demands,' he added. A passenger, Virendra Singh, said that everyone across the state is facing issues due to the protest, urging the government to resolve the drivers' demands. 'I had to pay extra Rs 1600 for my commute, as the transport services have been halted... The government must listen to the drivers' demands... Everyone across the state is facing issues,' he said. The strike has crippled transportation, leaving hundreds of people stranded at various bus stands. Fear of a fuel shortage has also led to long queues at fuel stations. Meanwhile, Chief Minister Mohan Charan Majhi, after attending the 27th Eastern Zonal Council meeting held in Ranchi, said that next year the 28th Eastern Zonal Council meeting will be held in Odisha's Puri. The Chief Minister said that he had proposed to hold this meeting in Odisha next year and this was accepted by Union Minister Amit Shah and all other members. It was announced in the meeting that it will be held in Puri. (ANI)

28th annual Memorial Day Observance ceremony at Veterans Memorial Park & Museum
28th annual Memorial Day Observance ceremony at Veterans Memorial Park & Museum

Yahoo

time25-05-2025

  • General
  • Yahoo

28th annual Memorial Day Observance ceremony at Veterans Memorial Park & Museum

The Brief The 28th annual Memorial Day Observance ceremony is being held at the Veterans Memorial Park & Museum on Sunday at 10 a.m. Local Gold Star family members will be honored with "Garden of Gold" pictorial flags. Attendees will be greeted by an enormous American flag soaring more than 150 feet over the entrance to Veterans Memorial Park. TAMPA - The 28th annual Memorial Day Observance ceremony will take place at Veterans Memorial Park & Rear Admiral LeRoy Collins, Jr. Veterans Museum on Sunday at 10 a.m. Local Gold Star family members will be honored with "Garden of Gold" pictorial flags and attendees will be greeted by an enormous American flag soaring more than 150 feet over the entrance to Veterans Memorial Park. The celebration will honor veterans and their families who made the ultimate sacrifice. Local perspective In attendance will be a few special guests: Col. Jeff J. Mrazik, Commander, 6th Operations Group, MacDill Air Force Base, Retired U.S. Army Col. Alfred "Al" Carter, Chief of Staff, Florida Department of Veteran Affairs and Junior Reserve Officers' Training Corps (JROTC). A rifle salute and taps will also be a part of the ceremony. READ: Manatee County World War II veteran receives highest honor from France Hillsborough County's Veterans Memorial Park is open daily from 7 a.m. to 5 p.m., with free admission and parking. CLICK HERE:>>>Follow FOX 13 on YouTube The Source Information for this story was provided by Hillsborough County. STAY CONNECTED WITH FOX 13 TAMPA: Download the FOX Local app for your smart TV Download FOX Local mobile app: Apple | Android Download the FOX 13 News app for breaking news alerts, latest headlines Download the SkyTower Radar app Sign up for FOX 13's daily newsletter

Where Continents Converge: Fez Sacred Music Festival Kicks Off with a Renaissance of Spirit
Where Continents Converge: Fez Sacred Music Festival Kicks Off with a Renaissance of Spirit

Morocco World

time17-05-2025

  • Entertainment
  • Morocco World

Where Continents Converge: Fez Sacred Music Festival Kicks Off with a Renaissance of Spirit

Fez – As the sun set over the ancient walls of Bab Makina, the 28th Fez Festival of Sacred Music transported audiences into a realm where tradition and transcendence intertwined. This year's opening night, curated under the visionary theme 'Renaissances: From Nature to the Sacred,' presented a meticulously crafted journey through sound, movement, and spiritual expression, bringing together an extraordinary ensemble of artists from across continents and traditions. Morocco's Princess Lalla Hasnaa presided over the opening ceremony of the 28th annual Fez Festival of World Sacred Music. The first day of the festival featured Le Deba, the mesmerizing Sufi ritual performed by women from Mayotte in the Comoros Islands, their chants and swaying movements invoking centuries of devotional practice. From this foundation of African Sufism, the stage welcomed Omar Areej Mawlidi, whose soulful Omani Sufi chants bridge the Arabian Peninsula with North African spirituality. Guiding the audience through this odyssey is Malian actor and storyteller Habib Dembélé, whose resonant narration wove together the evening's diverse performances with the timeless power of oral tradition. West Africa's kaleidoscopic sacred arts took center stage as Le Zaouli de Manfla unfolded, its intricate masked dance embodying ancestral wisdom through breathtaking precision. The rhythm intensified with the towering presence of Les Échassiers, their stilted movements creating a living bridge between earth and sky, followed by the Compagnie Méhansio from the Ivory Coast, whose ritual leopard dance channeled raw, primal energy through disciplined artistry. The spiritual journey continued with Senegal's Kassaïdes mourides from Dahira Safinatoul Aaman, their devotional hymns celebrating the Sufi path of Sheikh Amadou Bamba. Morocco's mystical heritage showed is real colors through Le Sama de Meknès, where whirling dervishes spun in celestial harmony, their movements a visual prayer. A striking counterpoint emerged as Corsican mezzo-soprano Battista Acquaviva breathed new life into Renaissance sacred music, her crystalline voice echoing through the courtyard like a revelation from another age. The evening reached its crescendo with the thunderous Tambours du Burundi, whose polyrhythmic mastery transformed the space into a pulsating temple of sound. Behind this multisensory masterpiece stands a team of visionary creators: Alain Weber's masterful conception and staging, Jean-Paul Méhansio's evocative choreography, Christophe Olivier's luminous lighting design (assisted by Gaël Boucault), and Spectaculaires' immersive mapping projections. As the final notes faded into the Fez night, this opening ceremony stood as a living testament to the festival's enduring mission to show, through the universal language of sacred art, the profound connections that bind humanity across cultures, eras, and beliefs. With eight more days of programming ahead, the 28th edition promises to be a true renaissance of the spirit, inviting all who attend to rediscover what it means to be human in an ever-changing world. Tags: Fez World Sacred Music FestivalMorocco culturesacred musicSufi music

Dyno Therapeutics Launches Three Breakthrough Capsid Delivery Vectors for Next-Generation Eye, Muscle and CNS Gene Therapies at the 2025 American Society of Gene & Cell Therapy (ASGCT) Annual Meeting
Dyno Therapeutics Launches Three Breakthrough Capsid Delivery Vectors for Next-Generation Eye, Muscle and CNS Gene Therapies at the 2025 American Society of Gene & Cell Therapy (ASGCT) Annual Meeting

Business Wire

time14-05-2025

  • Business
  • Business Wire

Dyno Therapeutics Launches Three Breakthrough Capsid Delivery Vectors for Next-Generation Eye, Muscle and CNS Gene Therapies at the 2025 American Society of Gene & Cell Therapy (ASGCT) Annual Meeting

WATERTOWN, Mass.--(BUSINESS WIRE)-- Dyno Therapeutics, Inc., a genetic technologies company applying artificial intelligence (AI) to solve the grand challenge of in vivo gene delivery, today announced the launch of three new adeno-associated virus (AAV) capsid gene delivery vectors targeting the eye, musculoskeletal system and central nervous systems (CNS), each with best-in-class potential. Key data from the capsids were presented in a Scientific Symposium at the 28th American Society of Gene & Cell Therapy (ASGCT) Annual Meeting and in three oral abstract presentations. 'I'm excited for Dyno to expand our offerings for our gene delivery partners with these new optimized capsids that more efficiently and more specifically deliver therapeutic genes to the eye, muscle and brain,' said Eric Kelsic, Ph.D., CEO and Cofounder of Dyno. 'These new capsids advance the frontiers of gene delivery, bringing Dyno's partners and the field one key step closer to realizing the full potential of genetic medicine to transform patient lives.' Ineffective delivery of therapeutic genes to specific organs and cells in vivo is the most limiting challenge for gene therapy today. Dyno's platform applies advanced AI models trained on data from high-throughput in vivo measurements in animal models to design AAV capsids that are optimized for delivery efficiency, precision targeting, and manufacturability. By sharing these improved gene delivery technologies with partners, Dyno aims to improve the effectiveness of genetic medicines, reducing delivery costs and accelerating the development of optimized therapies that address a wide range of human health challenges via genetic perturbations that address the root cause of each disorder. Each Dyno capsid was optimized and validated for in vivo delivery to cynomolgus monkey (Macaca fascicularis), the most relevant non-human primate (NHP) model for predicting translation potential for human therapy. Dyno's presentations highlighted the optimized performance, translatability, and manufacturability of the Dyno-4z2 capsid for eye delivery, Dyno-3hv capsid for neuromuscular delivery, and Dyno-ahq capsid for CNS delivery: Dyno-4z2 for Eye Delivery The Dyno-4z2 capsid is optimized for delivery to the retina upon intravitreal (IVT) injection and shows exceptional efficiency transducing bipolar cells in the inner nuclear layer (INL), supporting its use in optogenetic ocular gene therapies to restore vision for patients with retinal degeneration: Greater than 40-fold improvement in broad retinal transduction compared to AAV2 at doses of 1e10-1e11 vg/eye in NHP. A 5-fold improvement in transduction of bipolar cells and across the INL in NHP compared to a reference externally engineered capsid, an improvement also observed when both capsids were tested in mice. Easy to administer via IVT injection, enabling broader patient access compared to more invasive subretinal injections. Manufacturable at large scales and compatible with AAV2-based processes. Dyno-3hv for Neuromuscular Delivery Dyno-3hv is the first AAV capsid to demonstrate highly-efficient and enhanced delivery to the multiple tissues affected by neuromuscular disorders, enabling high efficient delivery to heart, skeletal muscle and brain with a single drug product: Transduces 53-90% of skeletal myofibers and multiple regions of the heart and CNS with IV injection at a dose of 4e12 vg/kg in NHPs. Potential for safer IV dosing through liver detargeting, with <10 vg/dg observed in liver in NHP after IV dosing at 4e12vg/kg and low biodistribution to other off-target organs. Easy to administer via IV injection, enabling broader patient access compared to more invasive intracranial and intramuscular injections. Identification of a novel receptor for crossing the blood-brain-barrier (BBB) and demonstration of conserved Dyno-3hv binding to both NHP and human orthologues supports translation for human therapies. Easily manufactured at large scale and compatible with AAV9-based processes. Dyno-ahq for CNS Delivery Dyno-ahq is optimized for widespread and efficient delivery to the brain and throughout the CNS upon IV injection. With enhanced CNS delivery efficiencies compared to prior Dyno capsids, exceptional increases in liver detargeting, and a known mechanism for crossing the BBB that is conserved between NHPs and humans, Dyno-ahq has exceptional utility for delivering gene therapies addressing neurological diseases: Reaches up to 30% of neurons in NHP after crossing the BBB at a dose of 3e13 vg/kg, a 280-fold increase in efficiency compared to the AAV9. Liver detargeting in NHP by greater than 50-fold compared to AAV9, with more neurons being transduced in the brain than hepatocytes in the liver. Easy to administer via IV injection, enabling broader CNS transduction and broader patient access compared to more invasive intraparenchymal and intracisternal injections. Identification of a novel receptor for crossing the BBB and demonstration of conserved Dyno-ahq binding to both NHP and human orthologues supports translation for human therapies. Easily manufactured at large scale and compatible with AAV9-based processes. In addition to unveiling the new capsids, the Dyno Scientific Symposium, 'Leveling up genetic medicine with frontier AI and AAV vectors for CNS, eye, and muscle,' provided updates on Dyno's frontier AI algorithms and strategy to rapidly advance next-generation gene therapies incorporating these capsids into human clinical trials by expanding partnerships with gene therapy developers, towards approval of new treatments in areas of high unmet patient need. Licensing Dyno Capsid Technology Alongside the previously released Dyno-86m (also known as Dyno eCap™ 1) optimized for eye delivery, and Dyno-hc9 (also known as Dyno bCap™ 1) capsid optimized for brain delivery, the Dyno-4z2, Dyno-3hv and Dyno-ahq capsids and additional proprietary platform technologies are available for licensing to Dyno's gene therapy partners. 'By solving the grand challenge of in vivo delivery with optimized capsids, our goal is to enable Dyno's partners to transform patient lives with breakthrough genetic medicines,' says Kelsic. 'With breakthrough new capsids like Dyno-4z2, Dyno-3hv, and Dyno-ahq, we are advancing the frontiers of delivery across therapeutic areas. These innovations reflect the quality and depth of our in vivo data, the power of our AI algorithms for sequence design, and our commitment to helping partners develop exceptional gene therapies that are safe, highly-effective and accessible to patients worldwide.' About Dyno Therapeutics Dyno Therapeutics' mission is to build high-performance genetic technologies that transform patient lives. Dyno is creating better technologies for gene delivery and sequence design to increase 'Genetic Agency'—the capacity for patients to take action and improve their health at a genetic level—enabling individuals to live the life they choose through safe, effective and widely accessible genetic treatments. With frontier AI models and high-throughput in vivo experimentation, Dyno designs optimized AAV delivery vectors that solve gene delivery challenges across a wide range of therapeutic applications. Dyno partners across industries to ensure these life-transforming technologies can help as many patients as possible, including strategic collaborations with leading gene therapy developers Astellas, Roche and Sarepta, and with technology companies including NVIDIA. Visit for more information. Forward-Looking Statements: The capsids described are investigational and intended for future clinical development. References to delivery performance or therapeutic potential are based on preclinical data and do not imply regulatory approval or clinical validation. Licensing is subject to agreement terms.

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