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Everything You Need to Know About Perimenopause
Everything You Need to Know About Perimenopause

Vogue Arabia

time06-07-2025

  • Health
  • Vogue Arabia

Everything You Need to Know About Perimenopause

Perimenopause deserves our full attention. Once considered a taboo topic, this transitional life stage is finally taking centre stage in women's health conversations, blending clinical science with emotional intelligence. From hormone diagnostics and HRT to mindset shifts and sleep rituals, this is your definitive guide to navigating perimenopause with clarity, confidence, and care. What is perimenopause, really? "Perimenopause is the transition period leading up to menopause, typically beginning four to ten years beforehand," explains Dr Alla Zaentc, Functional Medicine & Longevity Specialist at AEON Clinic, Atlantis The Royal, Dubai. It's a time of fluctuating estrogen and progesterone levels, which send ripples through virtually every system in the body: reproductive, metabolic, neurological, and emotional. While menopause is diagnosed retrospectively after 12 consecutive months without a period, perimenopause is often harder to define. "Symptoms can be subtle at first, irregular periods, brain fog, mood swings, even heart palpitations," says Dr. Zaentc. "But they're all signals from the body that change is underway." The hidden signals Beyond hot flashes and night sweats, many symptoms of perimenopause fly under the radar. Think joint aches, sudden anxiety, thinning hair, or migraines that now feel different. "One of the earliest signs is disrupted sleep," notes hormone health coach Laure Sejean. "Waking between one and three am can signal liver overload. Later in the night? That might be cortisol surges." Other overlooked clues include reduced libido, trouble concentrating, and unexplained weight gain, especially around the midsection. "Women often tell me, 'I haven't changed anything, but my body feels completely different,'" Sejean shares. It's not in your head. It's in your hormones. Hormones in flux During perimenopause, estrogen and progesterone don't simply decline. They spike and crash erratically. "This hormonal rollercoaster affects everything from serotonin levels and metabolic rate to bone density and cardiovascular health," says Dr. Zaentc. High follicle-stimulating hormone (FSH) and low anti-Müllerian hormone (AMH) are key markers, but perimenopause remains largely a clinical diagnosis, best understood through symptoms, not just labs. "Women need to be heard, not just tested," Dr. Zaentc stresses. Medical meets holistic: two paths to support At AEON Clinic, treatment begins with a full-body, lifestyle-led evaluation, incorporating sleep, nutrition, stress, and fitness. Hormone Replacement Therapy (HRT) is considered when symptoms are severe, and a woman is within 10 years of menopause onset. "When used appropriately, HRT can improve quality of life and prevent long-term health risks like osteoporosis," says Dr. Zaentc.

The skincare brand Noble Panacea partners with AEON Clinic
The skincare brand Noble Panacea partners with AEON Clinic

Emirates Woman

time02-06-2025

  • Business
  • Emirates Woman

The skincare brand Noble Panacea partners with AEON Clinic

This month, the Nobel Laureate-founded luxury skincare brand Noble Panacea officially launches in the region through an exclusive partnership with AEON Clinic. The setting? In the Middle East's first and only Regenerative & Longevity Wellness Centre affiliated with the American Board of Regenerative Medicine, located in none other than Atlantis The Royal – one of Dubai's prestigious properties. THE PARTNERSHIP For Noble Panacea, this move is more than just a regional debut—it's a meeting of minds with a like-minded partner in high-tech healing. 'This collaboration reflects a perfect alignment of values, as both Noble Panacea and AEON share a commitment to cutting-edge technology, advanced skin expertise, and holistic approaches to longevity and optimal skin health,' says Audrey Bois Nicolaï, Co-Creator and Brand VP of Noble Panacea. 'Created by a Nobel Laureate, our brand brings a unique dimension of scientific innovation to complement AEON's state-of-the-art expertise… and this partnership offers them the ultimate fusion of innovation, technology, well-being, and indulgence. Together, we will deliver an unparalleled skincare experience that immerses clients in luxury while empowering skin health and longevity at the pinnacle of high-tech wellness.' For Dr. Jaffer Khan, Founder & Executive Chairman of AEON Clinic, the collaboration was organic on the outset: 'At AEON Clinic, our dedication to providing advanced regenerative aesthetic treatments aligns seamlessly with Noble Panacea's scientifically formulated products. By incorporating their exceptional solutions into our treatments, we are enhancing the results our clients experience, offering them the highest standard of rejuvenation and well-being,' he adds. To celebrate the partnership, an intimate media lunch was hosted, followed by an afternoon of insightful discussions and a personalised walkthrough at the AEON Clinic, giving guests a first look at what happens when cutting-edge skincare meets curated wellness. THE CLINIC Founded by renowned plastic surgeon Dr. Jaffer Khan, AEON Clinic is where regenerative medicine and cellular-level rejuvenation are a focus. The state-of-the-art clinic boasts age-defying technology and science-driven therapies, from exosome therapy, stem cell treatments, IV drips, and peptide programmes that rejuvenate and transform skin health– all delivered with aesthetic excellence. THE SKINCARE Created by Nobel Laureate Sir Fraser Stoddart, Noble Panacea's patented OSMV™ technology is the cornerstone of the brand, delivering active ingredients in a time-released, micro-dosed system across its five skincare collections, such as The Absolute, The Exceptional, The Elemental, The Brilliant, and The Energist. Meticulously created with efficacy and intelligence for maximum potency, the products are housed in a minimalist octagonal starch-based, refillable packaging. – For more on luxury lifestyle, news, fashion and beauty follow Emirates Woman on Facebook and Instagram Images: Supplied

Price of youth: Dubai's AEON Clinic leads push for biological age reversal with DNA targeted treatments
Price of youth: Dubai's AEON Clinic leads push for biological age reversal with DNA targeted treatments

Arabian Business

time26-05-2025

  • Business
  • Arabian Business

Price of youth: Dubai's AEON Clinic leads push for biological age reversal with DNA targeted treatments

Biological age reversal, once relegated to the realm of science fiction, is fast becoming a clinical reality. Dubai's AEON Clinic offers several highly advanced treatments to clientele looking to achieve longevity, propelled by the vision of Founder and CEO Dr. Jaffer Khan. A veteran reconstructive and aesthetic surgeon in the UAE, Khan is placing a bold bet on the future of healthcare: reversing biological age through precision and regenerative medicine. From his clinic at Atlantis The Royal in Dubai, Khan is leading AEON Clinic, a high-end medical facility focused on extending healthspan rather than simply treating illness. The clinic targets a wealthy, globally mobile clientele with the promise of data-driven, preventive care that leverages cutting-edge science – from stem cell therapies to genomic sequencing. 'We're reversing biological age by looking at parameters such as DNA methylation,' said Khan in an exclusive interview with Arabian Business. 'There's an objective parameter that is changing. Your age is moving backwards biologically, not chronologically.' Although the price point remains high today, Khan is confident that as the technology scales and becomes more widely adopted, age-reversal treatments will move beyond the domain of the wealthy and become accessible to a broader population. Khan stresses that the approach at AEON Clinic is grounded in rigorous science rather than hype. 'We're not promising anything, you know. I mean, people come and they spend whatever $50,000 on a stem cell treatment, they are doing it knowing that we're not saying that this is going to be a game changer, a life changer for you.' The clinic provides patients with detailed diagnostics and clear benchmarks: 'Here is the science. Here is your current parameter. This is where we believe we can take you, and the rest is your journey,' he said. Data protection remains a pivotal challenge as healthcare moves deeper into personalised medicine. Khan believes that there can be excessive caution at times. 'I don't care if somebody knows my blood type. How is it going to change my life?' However, he calls for balanced regulation, 'HIPAA compliance has to happen. Okay? It has to be HIPAA compliant. You have to protect that data.' The ethical landscape surrounding regenerative medicine is complex, particularly concerning stem cell therapies. Khan pointed out the significant issues tied to embryonic stem cells. 'From an ethical perspective, regenerative medicine is right up there from stem cell technology, embryonic like, for example, one type of stem cells embryonic, but you have to kill the embryo to get it. So there's a huge ethical issue with that.' Yet the promise of such science is enormous. Breakthroughs in genetic engineering offer tantalising glimpses of the future. Khan highlighted experiments in animals demonstrating profound regenerative effects. 'Already in mice experiments, they are reversing age, growing their hair back. Blind mice are seeing again… You know all of these, what we call gene splicing, or gene transcription. It's there.' Technologies like CRISPR, which allow for precise editing of genetic sequences, have opened new frontiers. 'Since 2012 we can remove a bad segment of genomics and add a segment in what it costs for something like cystic fibrosis, maybe $2 million at the moment, but it won't be in 10 years' time,' Khan said. The dramatic drop in the cost of genome sequencing exemplifies how quickly the field is evolving. 'You know, it costs a billion dollars to decide for 3 billion to decipher the whole human genome. We do that now for $1,000 you know, as a test.' With technology advancing rapidly, treatments now available only to a wealthy few are expected to become broadly accessible. 'Although these treatments currently come with a considerably high price tag, Khan believes that in a few years when these technologies become more accessible and widespread – the service will not only be for the wealthy.' A critical part of AEON Clinic's philosophy is the long-term relationship it builds with patients. 'We're not just another retreat or one-off center. This is an ongoing clinical relationship based on diagnostics, biomarkers, and long-term planning,' Khan explained. Despite the promise of regenerative and precision medicine, Khan is clear-eyed about the importance of managing expectations. 'From an ethical point of view, we need to make sure that we introduce things without over delivering too many promises.' The clinic's approach is rooted in prudence: 'We should under promise and over deliver, rather than the other way around.' As longevity science advances, AEON Clinic is positioning itself to be a regional leader in a field that may redefine the future of healthcare. But Khan cautioned that the journey is just beginning and the technology still has to mature: 'This technology will be more and more available.' For now, patients willing to invest significant sums are embarking on what Khan calls a personal journey – one supported by cutting-edge diagnostics and treatments. 'We're reversing biological age… but what are the promises? We're not promising anything… This is where we believe we can take you, and the rest is your journey,' he concluded.

AEON Clinic positions Dubai as global hub for longevity medicine with pioneering masterclass
AEON Clinic positions Dubai as global hub for longevity medicine with pioneering masterclass

Arabian Business

time13-05-2025

  • Health
  • Arabian Business

AEON Clinic positions Dubai as global hub for longevity medicine with pioneering masterclass

AEON Clinic has concluded its Next-Generation Medicine 2025 Masterclass, a five-day programme that brought together global leaders in regenerative medicine, precision healthcare, and longevity science. Hosted across Atlantis The Palm and Atlantis The Royal, the internationally certified masterclass marks a significant step forward in Dubai's ambitions to lead in medical innovation and education. With accreditation from both international authorities and the Dubai Health Authority (DHA), the event attracted over 150 medical professionals, researchers, and innovators from across the globe. Attendees engaged in keynote sessions, case studies, and scientific workshops that explored cutting-edge treatments in age reversal, stem cell therapy, gene editing, mitochondrial medicine, immunotherapy, and photobiomodulation. A convergence of global expertise The masterclass featured presentations from more than 30 world-renowned experts, including Prof. David Barzilai, Prof. Brian Kennedy, Dr. Evelyne Bischof, Prof. Karim Nayernia, and Dr. Michael Weber. AEON Clinic's own medical team, including founder Dr. Jaffer Khan, joined the international faculty in showcasing the clinic's approach to integrating regenerative science with luxury patient care. In addition to the main programme, 60 selected participants received exclusive hands-on training at Atlantis The Royal in specialised workshops ranging from facial harmony injectables and thread lifting to photobiomodulation and ozone therapy. The event's thematic tracks reflected the broad scope of modern longevity science, including: Regenerative Medicine & Advanced Therapeutics – exploring stem cells, gene editing, and CRISPR Precision & Functional Medicine – using genomics and AI for predictive care Longevity & Biological Age Reversal – diving into age-related biomarkers and lifestyle interventions Neurodegenerative & Autoimmune Disorders – unveiling treatments for Parkinson's, Alzheimer's, and more Regenerative Aesthetics – demonstrating protocols involving exosomes, threads, and photobiomodulation Pharmacogenomics & Personalised Medicine – shaping the future of drug response analytics By emphasising clinical translation, the masterclass aligned with AEON's mission to embed evidence-based, preventive healthcare practices in everyday clinical settings. Influential participation and strategic support In attendance were high-level figures from the Dubai Health Authority, including Dr. Younis Mohamed Kazim, CEO of the Health Regulation Sector, and Dr. Latifa Ahmad Al Rustamani, Director of Medical Education & Research. Other notable attendees included Dr. Mariam Mohamed Fatima Matar, Founder & Chairperson of the UAE Genetic Diseases Association, alongside senior executives from Atlantis Resorts. The event was backed by strategic alliances with institutions such as the American Board of Regenerative Medicine, Geneva College of Longevity Science, and P7Medicine, positioning AEON as the only clinic in the Middle East affiliated with ABRM. 'This masterclass represents a shift – not only in the way we treat ageing and chronic disease but in how we educate, collaborate, and evolve as a medical community,' said Dr. Jaffer Khan, Founder of AEON Clinic. Following the success of this inaugural event, AEON Clinic has announced plans to host the Next-Generation Medicine Masterclass annually, establishing Dubai as a central node in the global movement toward longevity-first, data-driven healthcare systems.

AEON Clinic hosts the Future of Medicine: AEON's masterclass unites global pioneers in longevity
AEON Clinic hosts the Future of Medicine: AEON's masterclass unites global pioneers in longevity

Gulf Business

time09-05-2025

  • Health
  • Gulf Business

AEON Clinic hosts the Future of Medicine: AEON's masterclass unites global pioneers in longevity

Image credit: Supplied The global medical community turned its attention to Dubai as AEON Clinic concluded its highly anticipated Next-Generation Medicine 2025 Masterclass, a five-day certified event that brought together the most distinguished minds in longevity science, regenerative medicine, precision healthcare, and neurodegeneration. Held across Atlantis The Palm and Atlantis The Royal, the event marked a pivotal moment for the region's evolution in medical innovation and education. Certified internationally and by the Dubai Health Authority, the masterclass delivered accredited CME hours and served as an immersive forum for medical professionals, researchers, biohackers, and longevity specialists to exchange knowledge, share pioneering research, and demonstrate breakthrough protocols that will define the next era of personalised and preventive medicine. Image credit: Supplied Global convergence of innovation, clinical insight Over the course of the event, more than 150 medical professionals, scientists, and innovators attended the three-day masterclass, while 60 selected participants engaged in intensive, hands-on scientific workshops held at Atlantis The Royal. The programme brought together an unparalleled community of healthcare leaders, united by a shared commitment to advancing the science of longevity. Over five days, more than 30 leading global experts delivered keynote talks, live case studies, and hands-on demonstrations, offering insights into the latest breakthroughs in stem cell therapy, mitochondrial medicine, photobiomodulation, gene editing, immunotherapy, and age-reversal technologies. With a strong emphasis on translating science into patient-centred clinical practice, the event marked a pivotal step in shaping the future of integrative, preventive, and regenerative medicine. Image credit: Supplied Featured speakers Prof. David Barzilai Prof. Brian Kennedy Dr. Evelyne Bischof Prof. Zeynab Nayernia Dr. Tomasz Chelmicki Dr. Giuseppe Mucci Prof. Uwe Nixdorff Prof. Karim Nayernia Prof. Jürgen Hescheler Dr. Shaikha Almazrouei Prof. Sean Ng Dr. Nicole Sirotin Prof. Dominik Thor Dr. Michael Weber Dr. Kamran Mansouri Dr Mishkat Shehata, among others Image credit: Supplied AEON's own medical experts Dr. Jaffer Khan Dr. Saba Habibollah Dr. Salman Gilani Dr. Alla Zaentc Dr. Imane Farhat Dr. Basanta Khatry-Chhetry Dr. Mazen Al Samarrae Dr. Ecaterina Lica Dr. Francisco de Melo The sessions showcasing AEON's unique approach to bridging regenerative medicine and luxury patient care in Dubai, was led by AEON's own medical experts. Image credit: Supplied Masterclass highlights: From science to practice Key agenda tracks included: • Regenerative Medicine & Advanced Therapeutics – exploring stem cells, gene editing, and CRISPR • Precision & Functional Medicine – using genomics and AI for predictive care • Longevity & Biological Age Reversal – diving into age-related biomarkers and lifestyle interventions • Neurodegenerative & Autoimmune Disorders – unveiling treatments for Parkinson's, Alzheimer's, and more • Regenerative Aesthetics – demonstrating protocols involving exosomes, threads, and photobiomodulation • Pharmacogenomics & Personalised Medicine – shaping the future of drug response analytics Image credit: Supplied Gathering of visionaries, VIPs The event was attended by a curated group of medical innovators, healthcare investors, and government delegates, along with regional influencers and public figures dedicated to health and wellness. The following VIP attendees were given access to exclusive wellness experiences and behind-the-scenes discussions with faculty: • Dr Younis Mohamed Kazim- Consultant & CEO- Health Regulation Sector, Dubai Health Authority • Dr. Latifa Ahmad Al Rustamani – Director of Medical Education & Research Dept, Dubai Health Authority • Paul Baker – President, Atlantis Resorts • Marie-Elise Lallemand – Vice President, Hotel Operations | Atlantis, The Royal • Dr Mariam Mohamed Fatima Matar, Founder & Chairperson, UAE Genetic Diseases Associations Image credit: Supplied Strategic alliances that power innovation The Masterclass was made possible with the support of AEON Clinic's global collaborators and academic institutions. Strategic partners included: • P7MEDICINE: International Center for Personalized Medicine Ltd • American Board of Regenerative Medicine (ABRM) • Geneva College of Longevity Science (GCLS) • Bioscience • Fusion These partnerships reinforced AEON's position as the only clinic in the Middle East affiliated with the American Board of Regenerative Medicine and as a thought leader advancing medical education and integrative care. Image credit: Supplied Workshops that delivered hands-on transformation In the scientific workshops held at Atlantis The Royal, 60 selected attendees received live, in-depth instruction from global leaders in procedures such as: • Facial Harmony & Regenerative Injectables – led by Dr. Jaffer Khan • Precision Thread Lifting – demonstrated by Dr. Ecaterina Lica • Photobiomodulation Techniques – taught by Dr. Michael Weber • Ozone Therapy Protocols – conducted by Dr. Basanta Khatry-Chhetry The sessions combined theory, live cases, and immersive learning – reinforcing AEON Clinic's dedication to advancing evidence-based longevity medicine in the region. Image credit: Supplied A statement of intent for Dubai's healthcare future As the curtains closed on a transformative five days, AEON Clinic affirmed its mission to bring longevity science, data-driven wellness, and regenerative treatments to the forefront of modern healthcare. 'This masterclass represents a shift – not only in the way we treat ageing and chronic disease but in how we educate, collaborate, and evolve as a medical community,' said Dr. Jaffer Khan, Founder of AEON Clinic. The Next-Generation Medicine Masterclass will now become an annual flagship event, placing Dubai at the heart of a global movement toward longevity-first healthcare systems. Contact information AEON Clinic – Regenerative Wellness Centre Location : Atlantis The Royal, Crescent Rd, The Palm Jumeirah, Dubai Phone : +971 4 518 5777 Email : Website :

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