Latest news with #Alzheimer's-related
Malaysian Reserve
2 days ago
- Health
- Malaysian Reserve
CareONE Concierge Now Accepting Candidates for Alzheimer's Device Study
Study offers patients the opportunity to try an experimental, non-drug therapy for Alzheimer's using an FDA-designated Breakthrough Device ATLANTA, July 10, 2025 /PRNewswire/ — CareONE Concierge has announced the launch of a new research study to evaluate an innovative wearable device aimed at addressing cognitive symptoms associated with Alzheimer's-related dementia. The study will utilize NeuroEM Therapeutics'® TEMT-RF cap, a non-invasive device that has received Breakthrough Device designation from the U.S. Food and Drug Administration (FDA). Alzheimer's disease is a growing global health crisis, affecting nearly 7 million Americans and is projected to impact nearly 13 million by 2050. Despite decades of research, treatment options remain limited, with most current therapies only addressing symptoms rather than the underlying causes of cognitive decline. NeuroEM Therapeutics is pioneering Transcranial Electromagnetic Treatment using Radio Frequencies (TEMT-RF) as a potentially groundbreaking approach to treating the disease at its root. The lightweight, wearable device delivers electromagnetic waves similar to those produced by cell phone signals from multiple emitters. It is being investigated for its potential to break apart toxic protein oligomers within neurons throughout the brain. These oligomers—clusters of beta-amyloid and tau proteins—are thought to drive the progression of Alzheimer's disease. By disrupting these harmful accumulations, TEMT-RF may help restore neuronal function and slow cognitive decline. 'We all know friends and family members who have been impacted by Alzheimer's or dementia,' said Peter Bechtel, CEO of CareONE Concierge. 'This study represents a potential turning point in the fight against these devastating conditions. By participating in this study, individuals have the opportunity to experience cutting-edge, non-drug therapy while contributing to groundbreaking advancements in Alzheimer's treatment.' This study is independently conducted by CareONE Concierge and is designed for individuals with mild to moderate Alzheimer's-related dementia. Participants will be required to wear the device twice daily for one hour, follow a structured research protocol, and complete cognitive assessments throughout the study. Dr. Edward Goodwin, Chief Scientist at NeuroEM, emphasized the scientific foundation behind TEMT-RF, stating, 'Our research has shown that TEMT-RF has the potential to impact the key biological processes associated with Alzheimer's disease. This study will help us gather more real-world data on how the device affects cognitive function and overall brain health.' 'NeuroEM is excited to partner with CareONE Concierge,' stated Chuck Papageorgiou, CEO of NeuroEM Therapeutics. 'Our objective is to promote safe, effective, and non-invasive technologies for cognitive health, and research initiatives like this are essential in helping us uncover the full potential of TEMT-RF. With Alzheimer's cases increasing, innovative research such as this provides new hope for patients, caregivers, and the future of cognitive health. Together, we can take meaningful steps toward a future where memory loss is no longer an inevitable part of aging.' CareONE Concierge is now accepting qualified participants for the study. For more information or to apply, please email CT@ or apply at About CareONE ConciergeCareONE Concierge is committed to delivering Preventative Healthcare solutions that meet the needs of patients, providers, and the healthcare system. The company works with physicians, patients, and healthcare systems to develop turnkey solutions that increase patient outcomes while enhancing revenue and quality metrics. To learn more, visit . About NeuroEM Therapeutics®NeuroEM Therapeutics is leading the way in the development and clinical testing of bioengineered technology to reverse the cognitive decline associated with Alzheimer's disease and other neurodegenerative conditions. Built upon a decade of groundbreaking research conducted at Tampa-based research facilities at the University of South Florida (USF), the company received the first Breakthrough Device status from the U.S. Food and Drug Administration (FDA) to treat Alzheimer's disease. NeuroEM's continued dedication to cutting-edge research is bringing to market a first-in-class wearable device designed for in-home use to extend healthy longevity using patented Transcranial Electromagnetic Treatment leveraging Radio Frequencies (TEMT-RF) technology. To learn more, visit Media Contact:Wendy Stevens, Study Manager(919) 600-9930wstevens@
Yahoo
3 days ago
- Health
- Yahoo
These 5 Early Alzheimer's Warning Signs Are Often Mistaken for Normal Aging
You totally spaced on grabbing your gym bag (or apartment cell phone...) on your way to work in the morning. Or, you forgot to submit your cable bill payment online last week. Hey, no judgment—when it comes to getting older, forgetting stuff is part of the deal. But what if your memory loss doesn't seem like a typical part of getting older, and this is happening, like, all the time? If you're a woman, that's a serious question to consider. Two-thirds of all Alzheimer's patients and caregivers are female, according to the Women's Alzheimer's Movement, meaning women are disproportionately affected by the disease. While the reasons behind that reality aren't totally clear, hormones are likely at play. 'Women who have had hysterectomies, gone through early menopause, or had any early loss of estrogen are particularly vulnerable,' says David A. Merrill, MD, PhD, neurologist and geriatric psychiatrist at Providence Saint John's Health Center in Santa Monica. 'We know estrogen has a protective effect on the brain and supports healthy brain function.' To make matters worse, Dr. Merrill says the psychological and cognitive processes of getting older mimic the early warning signs of dementia syndromes (Alzheimer's is the most common one). So it can be easy to dismiss these first signs of brain degeneration as run-of-the-mill aging. Getting familiar with the early and first signs of the disease here—straight from neurologists!—will make you that much more prepared to take action if and when you notice something seems off with you or someone you love down the line. You're about to order your a.m. latte from your local coffee shop when you realize you can't remember the barista's she serves you five days a week. Is that bad? Probably not, says Henry Paulson, MD, PhD, neurologist and director of the University of Michigan's Alzheimer's Disease Center. 'As we age, our brains change,' he says. 'It's normal for things like our speed of thinking and recall of names to slow down.' Alzheimer's-related memory loss is more than just not being able to remember someone's name. '[We're talking about] forgetting major events or having a loss of whole episodes,' Dr. Paulson explains. For example, 'You don't remember going on a beach vacation for three days with your family or attending your grandchild's birthday party last weekend,' he says. Paulson adds that misplacing items—like consistently putting your car keys in the fridge or not knowing what room to find your toothbrush—also falls under the umbrella of memory loss, along with not knowing what day of the week or month it is. One more thing: Sometimes people will rely too heavily on tricks like repetition or note-taking to force themselves to remember things they know they'll forget—so if you (or a loved one) notice you're doing this, it's worth seeing a neurologist. If you're struggling with speaking or writing or experiencing visual impairments, it's also time to contact your doc. Early brain degeneration can make it hard to communicate and engage with your environment. 'You might notice spatial changes in your vision or even have difficulty perceiving the world around you,' explains Dr. Paulson. 'When you speak, you're having to take the long way around and come up with other phrases to explain what you need because you can't remember the exact word.' Again, these problems go beyond squinting at the television from across the room or writing the wrong date on your checks, which are all normal parts of aging; early Alzheimer's symptoms would likely be more obvious and ongoing. There are several red flags to look out for within this category, including trouble completing tasks, problem-solving, and displaying poor judgment. According to Dr. Paulson, our brains have to process a range of information in order to productively move through our day-to-day lives. The degeneration brought on by early Alzheimer's can make something as simple as choosing what to order for lunch a complicated decision. People in early stages of the disease may show other signs of cognitive deterioration such as being unable to follow directions or recipes, making serious financial errors, or struggling to maintain a healthy hygiene routine, per the Alzheimer's Association. Did you (or your aging mother, perhaps) used to be the life of every party—but now you're staying home more and more often from social gatherings? You could be experiencing a normal decrease in it could be an early warning sign of Alzheimer's. Dr. Paulson says when brain degeneration makes it hard to remember commitments, participate in conversations, or engage fully in social events, many people begin to withdraw from these activities. Sometimes this is a symptom of depression (which also shouldn't be ignored), but either way it's important to seek help if someone's behavior seems out of character for them. Speaking of out-of-character behavior, when you or someone you love starts acting like a total stranger, it's time to take those changes seriously. 'This is a little more rare, but we do see it in the early stages,' says Dr. Paulson. 'It looks like someone who knows right from wrong suddenly becoming uninhibited, and doing things they never would normally do.' It may also manifest as a person having intense mood swings, becoming easily suspicious of others, or showing heightened aggression or sexual behaviors, per the National Institute on Aging. So if you're experiencing little memory flubs before your 60s, it's unlikely you're dealing with Alzheimer's symptoms (although you should always check in with your doctor if you're concerned). And if you need help determining the next steps for yourself or a loved one, the Alzheimer's Association offers a 24/7 helpline, patient and caregiver resources, and a directory of local support groups for people affected by the disease. You Might Also Like Jennifer Garner Swears By This Retinol Eye Cream These New Kicks Will Help You Smash Your Cross-Training Goals
Time of India
03-07-2025
- Health
- Time of India
Just a daily walk can help prevent dementia and heart disease
A simple activity like walking has life-saving benefits. If it is done correctly, it can be the key to losing weight, lowering blood pressure and cholesterol, and boosting your memory, as well as reducing your risk for heart disease, diabetes, cancer, and more. With the elderly population projected to reach 19.1% by 2050, the burden is expected to grow significantly. Parallelly, cardiovascular diseases (CVDs) continue to be the leading cause of death. In this context, lifestyle interventions like regular walking emerge as simple, cost-effective strategies to reduce the risks of both dementia and heart disease, especially among older adults in India. Understanding dementia and heart diseases in India According to the study published in the National Library of Medical Science (NLM), in India, dementia affects 7.4% of adults aged 60 and above, with variations based on age, education, gender, and rural or urban residence. Around 8.8 million individuals in this age group are living with dementia, necessitating tailored local planning and support, especially in states and subpopulations with higher prevalence among females and in rural areas. It is forecasted in the study of Changing demography and the challenge of dementia in India that by 2050, it is anticipated that 19.1% of India's population will be aged 60 years and above. Due to its large population, South Asia, particularly India, is expected to be a significant contributor to this rise, although variations may occur based on demographic differences in Kerala and Uttar Pradesh. Importance of walking speed to reduce risk of dementia The assessment of walking activity, conducted using the validated Lifetime Total Physical Activity Questionnaire, reveals that both the intensity and duration of walking play significant roles in influencing cognitive health outcomes. Participants were categorised based on walking frequency, intensity (low, moderate, or vigorous), and the stage of life when walking was initiated (midlife vs. late life). According to NLM research, physical activity is one of the protective and cost-effective practice activities against dementia, and recent studies show that even a single form of physical activity like walking can positively impact brain health. Walking requires no special training, costs nothing, and can be done almost anywhere, making it a practical choice across all ages. Importantly, a slow walking speed has been identified as a major risk factor for developing or worsening Alzheimer's-related symptoms. This implies an inverse relationship between walking and cognitive decline—the more consistently one walks, the lower the risk may be. Several long-term studies support this idea. For instance, older women who walked more frequently showed lower chances of cognitive decline over a period of 6–8 years. Similarly, elderly men who maintained regular walking routines had a significantly reduced risk of developing Alzheimer's dementia. Major findings indicate that individuals who engaged in regular, moderate-to-vigorous walking—especially those walking more than 360 minutes per week—showed a lower risk of Alzheimer's-related cognitive decline compared to non-walkers or those with lower-intensity activity. Notably, the timing of walking initiation also mattered: those who began walking in midlife (ages 40–64) demonstrated stronger cognitive protection than those who started in later life. How walking helps with heart diseases Multiple studies have shown that walking regularly, even for just 20 to 60 minutes a day, a few times a week, can significantly reduce key risk factors linked to heart disease. In a review of 14 walking-based intervention studies published in the National Library of Medical Science (published in 2009–2010), participants followed walking routines lasting anywhere from 3 weeks to 12 months. The results showed consistent improvements in cardiovascular fitness, which is a major factor in preventing heart disease. Participants reported better endurance, easier breathing during activity, and improved ability to exercise. Regular walking at a moderate intensity—the kind that makes you breathe faster, sweat lightly, or feel a bit flushed—was most effective in improving heart strength and blood flow. In some studies, walking even lowered blood pressure, especially in people with mild hypertension or those at risk due to age and other conditions. Other health benefits included: Reduced body fat and weight Improved cholesterol levels Increased distance walked without discomfort in people with circulation problems (like peripheral artery disease) These changes may seem small at first, but over time, they add up to a significant reduction in the risk of heart disease, stroke, and related complications. Also Read: What is prostate cancer: Causes, symptoms, risk factors, and healthy habits that help prevent it
New York Post
24-06-2025
- Health
- New York Post
Weight loss drugs like Ozempic may prevent dementia: study
Memory loss might have met its match. A new study from Case Western Reserve School of Medicine suggests that GLP-1 weight loss drugs like Ozempic and Wegovy could lower your risk of developing dementia. That's a potential game changer for the more than 6 million Americans diagnosed each year and the 100,000 who die from the memory-robbing disease annually. The risk of developing dementia increases with age. fizkes – The research team analyzed three years of health records from 1.7 million Americans with type 2 diabetes across the US. The findings were striking: patients taking semaglutide — the key ingredient in Ozempic and Wegovy — had a significantly lower risk of Alzheimer's-related dementia than those on other diabetes medications. The benefit was especially strong among women and older adults. 'There is no cure or effective treatment for dementia, so this new study provides real-world evidence for its potential impact on preventing or slowing dementia development among at-high risk populations,' said Dr. Rong Xu, lead author and professor of biomedical informatics. Researchers haven't nailed down exactly what causes dementia — but they do know what raises your risk. A 2024 Lancet Commission report found that up to 45% of dementia cases could be prevented by tackling key lifestyle factors like obesity, physical inactivity, type 2 diabetes, high blood pressure, alcohol use and even hearing loss. Semaglutide may help protect against dementia by reducing inflammation in the brain. alones – Semaglutide may hit several of those targets at once. The drug not only helps with weight loss, but also improves insulin sensitivity, lowers blood sugar, protects blood vessels and reduces inflammation in the brain — all key players in dementia risk. Next up, scientists want to see if newer GLP-1 drugs like tirzepatide — the active ingredient in Zepbound and Mounjaro — can also have a protective effect against dementia. They also plan to track potential long-term side effects. 'Our results indicate that research into semaglutide's use for dementia prevention will need to be further investigated through randomized clinical trials,' Xu said. While scientists hunt for a cure, there are still ways to get ahead of dementia. The CDC recommends staying active, keeping your blood pressure in check, treating hearing loss, and cutting back on alcohol and cigarettes to help keep your brain sharp.
Yahoo
12-06-2025
- Health
- Yahoo
Rosemary, sage could boost brain health: Study
(NewsNation) — A recent study has found that rosemary and sage may have a positive impact on brain health and reduce the risk of Alzheimer's disease. The study released in the Antioxidants journal shows a compound shared by the two herbs called carnosic acid has antioxidant and anti-inflammatory properties that shield brain cells from damage similar to what can lead to Alzheimer's. Researchers were able to create a more stable form of carnosic acid called diAcCA. Screen time a symptom, cause of emotional distress in kids: Study In preclinical studies, the researchers found that the compound improved memory, boosted brain synapses and reduced harmful Alzheimer's-related proteins like amyloid-beta and tau. The diAcCA compound only activates in inflamed brain regions, which could minimize side effects. To date, studies in mice have shown significant cognitive improvements and no signs of toxicity. Researchers are looking to start human trials soon. Researchers also believe diAcCA could help treat other inflammatory conditions, such as Type 2 diabetes, cardiovascular disease and Parkinson's disease. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
