Latest news with #ApellisPharmaceuticals
Yahoo
06-07-2025
- Business
- Yahoo
Morgan Stanley Raises PT on Apellis Pharmaceuticals (APLS) to $26, Keeps a Hold Rating
Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is one of the 13 Best Pharma Stocks to Buy According to Wall Street Analysts. On July 1, analyst Judah Frommer from Morgan Stanley raised the firm's price target on Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) to $26.00 from $25.00 while maintaining a Hold rating on the stock. Frommer attributed the rating to the company's market position and recent financial strategies. A biomedical scientist in a lab coat conducting research on biopharmaceutical compounds. He cited the company's significant royalty purchase agreement with Sobi, securing up to $300 million and including a $275 million upfront payment, stating that it would slash Sobi's royalty obligations on Aspaveli sales by 90%. This would result in immediate financial benefits for Apellis and may even ease investor concerns regarding the company's profitability. Despite this positive development, Frommer maintained a cautious outlook for Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) due to its future prospects. He stated that while the anticipated regulatory decisions from the FDA and CHMP and the launches of Empaveli/Aspaveli in new indications are significant events, they bring in as much uncertainty as confidence in the company's market potential. Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is a commercial-stage biopharmaceutical company that discovers, develops, and commercializes novel therapeutic compounds for treating diseases with unmet needs. Its product portfolio primarily includes EMPAVELI and SYFOVRE. SYFOVRE treats geographic atrophy secondary to age-related macular degeneration (GA), while EMPAVELI treats paroxysmal nocturnal hemoglobinuria (PNH). While we acknowledge the potential of APLS as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None.
Yahoo
06-07-2025
- Business
- Yahoo
Morgan Stanley Raises PT on Apellis Pharmaceuticals (APLS) to $26, Keeps a Hold Rating
Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is one of the 13 Best Pharma Stocks to Buy According to Wall Street Analysts. On July 1, analyst Judah Frommer from Morgan Stanley raised the firm's price target on Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) to $26.00 from $25.00 while maintaining a Hold rating on the stock. Frommer attributed the rating to the company's market position and recent financial strategies. A biomedical scientist in a lab coat conducting research on biopharmaceutical compounds. He cited the company's significant royalty purchase agreement with Sobi, securing up to $300 million and including a $275 million upfront payment, stating that it would slash Sobi's royalty obligations on Aspaveli sales by 90%. This would result in immediate financial benefits for Apellis and may even ease investor concerns regarding the company's profitability. Despite this positive development, Frommer maintained a cautious outlook for Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) due to its future prospects. He stated that while the anticipated regulatory decisions from the FDA and CHMP and the launches of Empaveli/Aspaveli in new indications are significant events, they bring in as much uncertainty as confidence in the company's market potential. Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is a commercial-stage biopharmaceutical company that discovers, develops, and commercializes novel therapeutic compounds for treating diseases with unmet needs. Its product portfolio primarily includes EMPAVELI and SYFOVRE. SYFOVRE treats geographic atrophy secondary to age-related macular degeneration (GA), while EMPAVELI treats paroxysmal nocturnal hemoglobinuria (PNH). While we acknowledge the potential of APLS as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
04-07-2025
- Business
- Yahoo
Apellis Pharmaceuticals, Inc. (APLS) Insider Activity Signals Possible Market Mispricing
Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is among the best growth stocks to invest in for the next 5 years. The General Counsel of Apellis Pharmaceuticals, Inc. (NASDAQ:APLS), David O. Watson, sold 5,000 shares of common stock for $18.77, higher than the current trading price of $17.62. This transaction, worth $93,850, although it follows a challenging period, implies the current undervaluation of the stock. This reduction of the stake means that Watson now owns 133,730 shares of Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) directly and 80,136 shares indirectly through a custodial account for his minor children and the David O. Watson Irrevocable Trust of 2023. With that being said, the execution of the sale was under a pre-arranged 10b5-1 trading plan. A biomedical scientist in a lab coat conducting research on biopharmaceutical compounds. Some analysts believe that if you hold this stock, you need to have some patience. They argue that the significant FCF potential of SYFOVRE and EMPAVELI can't be overlooked, with the market for SYFOVRE anticipated to exceed $1 billion in annual sales by 2028. EMPAVELI, on the other hand, is undergoing trials for additional indications and is expected to contribute to EBITDA positivity by 2026. Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is a Massachusetts-based commercial-stage biopharmaceutical company that discovers and commercializes novel therapeutic compounds for underserved diseases. Incorporated in 2009, the company has a license agreement with Swedish Orphan Biovitrum AB (publ) and Beam Therapeutics Inc. While we acknowledge the potential of APLS as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
13-06-2025
- Business
- Yahoo
Why Is Kodiak Sciences (KOD) Up 10.5% Since Last Earnings Report?
A month has gone by since the last earnings report for Kodiak Sciences Inc. (KOD). Shares have added about 10.5% in that time frame, outperforming the S&P 500. Will the recent positive trend continue leading up to its next earnings release, or is Kodiak Sciences due for a pullback? Before we dive into how investors and analysts have reacted as of late, let's take a quick look at the most recent earnings report in order to get a better handle on the important drivers. It turns out, estimates review have trended downward during the past month. The consensus estimate has shifted -10.35% due to these changes. At this time, Kodiak Sciences has a subpar Growth Score of D, though it is lagging a bit on the Momentum Score front with an F. Following the exact same course, the stock was allocated a grade of F on the value side, putting it in the lowest quintile for this investment strategy. Overall, the stock has an aggregate VGM Score of F. If you aren't focused on one strategy, this score is the one you should be interested in. Estimates have been broadly trending downward for the stock, and the magnitude of these revisions indicates a downward shift. Notably, Kodiak Sciences has a Zacks Rank #3 (Hold). We expect an in-line return from the stock in the next few months. Kodiak Sciences is part of the Zacks Medical - Biomedical and Genetics industry. Over the past month, Apellis Pharmaceuticals, Inc. (APLS), a stock from the same industry, has gained 17.7%. The company reported its results for the quarter ended March 2025 more than a month ago. Apellis Pharmaceuticals reported revenues of $166.8 million in the last reported quarter, representing a year-over-year change of -3.2%. EPS of -$0.74 for the same period compares with -$0.54 a year ago. For the current quarter, Apellis Pharmaceuticals is expected to post a loss of $0.44 per share, indicating a change of -57.1% from the year-ago quarter. The Zacks Consensus Estimate has changed -10.2% over the last 30 days. The overall direction and magnitude of estimate revisions translate into a Zacks Rank #4 (Sell) for Apellis Pharmaceuticals. Also, the stock has a VGM Score of F. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Kodiak Sciences Inc. (KOD) : Free Stock Analysis Report Apellis Pharmaceuticals, Inc. (APLS) : Free Stock Analysis Report This article originally published on Zacks Investment Research ( Zacks Investment Research Sign in to access your portfolio
Yahoo
09-06-2025
- Health
- Yahoo
Sobi and Apellis report new data from Phase III trial for C3G and IC-MPGN
Sobi and Apellis Pharmaceuticals have reported new results from the open-label period of the randomised Phase III VALIANT trial, assessing Aspaveli (pegcetacoplan) in treating C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN). The data were showcased during a late-breaking session at the European Renal Association Congress. This multi-centre, double-blinded, placebo-controlled study aims to assess the efficacy and safety of pegcetacoplan in 124 subjects who are aged 12 years and above with these conditions. Its primary endpoint was the log-transformed ratio in the urine protein-to-creatinine ratio (UPCR) at week 26 versus the baseline. Subjects were randomised and given the therapy or placebo two times a week for 26 weeks. After 26 weeks, the subjects were able to proceed to a 26-week open-label phase in which all of them received the therapy. At week 26, the therapy led to a 68% reduction in proteinuria compared to placebo, a benefit that persisted after one year. Those who received Aspaveli's treatment achieved kidney function stabilisation as per estimated glomerular filtration rate (eGFR) measurements. Subjects who transitioned from placebo to the therapy in the open-label phase experienced similar improvements in proteinuria and kidney function stabilisation. The tolerability and safety profile of Aspaveli, also known as Empaveli, remained favourable and aligned with previous findings, without any safety concerns. C3G and primary IC-MPGN are rare kidney conditions that can result in its failure. Sobi medical affairs and clinical development head Nils Kinnman said: 'The results from the Phase III VALIANT study underscore the potential of Aspaveli in addressing the urgent needs of patients living with the kidney diseases C3G and primary IC-MPGN.' Both companies share worldwide joint development rights for systemic pegcetacoplan, with Sobi holding exclusive rights ex-US and Apellis retaining US commercialisation rights and global rights for ophthalmological pegcetacoplan, inclusive of geographic atrophy. Last year, the companies reported positive topline data from the same Phase III VALIANT trial assessing pegcetacoplan in treating C3G and primary IC-MPGN. "Sobi and Apellis report new data from Phase III trial for C3G and IC-MPGN" was originally created and published by Clinical Trials Arena, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
