Latest news with #AveryBrown
Yahoo
22-06-2025
- Health
- Yahoo
One Weight Loss Strategy Is 5x More Effective Than Ozempic, Trials Show
Ozempic and other semaglutide medications have been working wonders in terms of shedding pounds for many people, but a new study shows that they're still not as effective as surgery when it comes to weight loss – and it's not even close. Researchers from New York University (NYU) compared sleeve gastrectomy and gastric bypass operations against semaglutide or tirzepatide. These drugs are known as glucagon-like peptide-1 (GLP-1) receptor agonists, because of the way they mimic the natural GLP-1 hormone, which controls appetite. Using health records, the team matched people who had taken one of the weight loss drugs with people who had undergone either of the bariatric surgery operations, based on age, body mass index, and blood sugar levels. The bottom line: people in the surgery group shed an average of 25.7 percent of their total body weight over two years, while those in the medication group lost 5.3 percent. That's partly down to patients not sticking to their GLP-1 drugs, whereas surgery is more permanent, but the researchers also noticed smaller differences over shorter time frames – the surgery always gave the best results. "Clinical trials show weight loss between 15 percent to 21 percent for GLP-1s, but this study suggests that weight loss in the real world is considerably lower even for patients who have active prescriptions for an entire year," says Avery Brown, a surgical resident at NYU Langone Health. "We know as many as 70 percent of patients may discontinue treatment within one year. GLP-1 patients may need to adjust their expectations, adhere more closely to treatment or opt for metabolic and bariatric surgery to achieve desired results." It's worth noting, however, that the study was funded by the American Society for Metabolic and Bariatric Surgery (ASMBS), who would have a vested interest in promoting surgical options. That said, the researchers aren't outright dismissing semaglutide treatments, which also showed beneficial results in this study. With GLP-1 prescriptions doubling from 2022 to 2023, it's crucial to investigate how they compare to established surgery methods, and to figure out which options are best for each individual. GLP-1 drugs remain much more popular than surgery, but people don't often stick to taking them. Meanwhile, only a small percentage of people eligible for surgery choose it as an option. Weight loss isn't the only benefit that can come from Ozempic. The drug was originally approved as a way to treat type 2 diabetes, because it helps lower blood sugar levels, and studies have shown it can also reduce the risk of cancer and cardiovascular disease. In this study, bariatric surgery was associated with even better blood sugar control. It's also important to note that surgery isn't a silver bullet either. Though safe, the procedures are invasive, permanent, and still require patients to stick to strict diet and exercise routines. "In future studies we will aim to identify what healthcare providers can do to optimize GLP-1 outcomes, identify which patients are better treated with bariatric surgery versus GLP-1s, and determine the role out-of-pocket costs play in treatment success," says Karan Chhabra, a bariatric surgeon at the NYU Grossman School of Medicine. The research was presented at the ASMBS annual meeting 2025. There's a Shocking Reason Ticks Are So Dangerous (It's Us) Cannabis Linked to 2x Risk of Heart Disease Death, Scientists Discover 5 Daily Habits Could Be Causing Your Liver Serious Harm
Time of India
18-06-2025
- Health
- Time of India
Weight-loss surgery more effective than drugs in real world study
London: Bariatric surgeries led to about five-times more weight loss than weekly injections of popular GLP-1 drugs , according to data from a real-world comparison study presented on Tuesday at the American Society for Metabolic and Bariatric Surgery scientific meeting in Washington. "Clinical trials show weight loss between 15% to 21% for GLP-1s, but this study suggests that weight loss in the real world is considerably lower even for patients who have active prescriptions for an entire year," study leader Dr. Avery Brown of NYU Langone Health said in a statement. Researchers reviewed records of 38,545 patients who were prescribed injectable semaglutide or tirzepatide between 2018 and 2024 and 12,540 patients who underwent bariatric surgery during the same period. Everyone started the study with a body mass index of at least 35, which is considered severe obesity. Semaglutide is the main ingredient in Novo Nordisk 's Wegovy and Ozempic, while tirzepatide is the main ingredient in Eli Lilly 's Zepbound and Mounjaro. At three years after undergoing sleeve gastrectomy or gastric bypass or starting the drugs, patients who underwent surgery had lost on average 24% of their starting weight, compared to about 5% for similar patients who used the drugs for at least six months and about 7% for those who took them for a year. Brown noted that as many as 70% of GLP-1 patients may discontinue treatment within one year. "While both patient groups lose weight, metabolic and bariatric surgery is much more effective and durable," ASMBS President Dr. Ann M. Rogers, who was not involved in the study, said in a statement. "Those who get insufficient weight loss with GLP-1s or have challenges complying with treatment due to side effects or costs, should consider bariatric surgery as an option, or even in combination," she said. NEW BLOOD TEST MAY REDUCE LIVER TRANSPLANT FAILURES An experimental blood test can help surgeons catch and identify problems with newly transplanted livers at early stages, researchers say. It's not unusual for transplanted organs and recipients' nearby tissues to sustain damage during the transplantation process. Hints of problems will show up later in routine blood tests, but identifying the precise site of the damage often requires costly imaging studies and surgical biopsies, according to a report published on Tuesday in Nature Communications. The new test works by picking up DNA fragments left behind in the blood by dying cells. The chemical signatures on these DNA fragments can be used to identify the original cell type and where it came from, with precise detail, the researchers found. If you can determine which part of the liver is injured - for example, the bile ducts, or the blood vessels - "you could provide a more personalized treatment approach that leads to better care for the patient," study leader Dr. Alexander Kroemer of MedStar Georgetown University Hospital in Washington, DC said in a statement. In addition to being faster and less invasive than a traditional biopsy, the blood test is also potentially more accurate, because biopsies only sample a few spots in the liver and might miss the site of the problem, he added. Georgetown has filed patent applications on the technology, and the research team is seeking partners to commercialize the test. DIABETES PRECURSOR SHOWS UP ON MUSCLE ULTRASOUND Ultrasound exams of thigh or shoulder muscles can detect insulin resistance at its earliest stages, researchers reported in the Journal of Ultrasound in Medicine. "We perform a large number of shoulder ultrasounds and noticed that many patients' muscles appear unusually bright," study leader Dr. Steve Soliman of the University of Michigan said in a statement. His team discovered in earlier studies that most of these patients have type 2 diabetes. But some had bright muscles on ultrasound even with no signs of diabetes or prediabetes. Subsequently, upon short-term follow-up, these patients often also developed prediabetes or type 2 diabetes. To test the potential for noninvasive muscle ultrasound as a predictive tool for detecting the development of pre- or type 2 diabetes - potentially earlier than current methods - the researchers performed muscle ultrasounds on 25 patients who were also being evaluated for insulin resistance. Although muscle ultrasound could detect insulin resistance and impaired insulin sensitivity, in this small study the level of brightness was not directly correlated with the degree of the condition. The researchers are recruiting more participants to continue the analysis. The exact reason why muscle brightness on ultrasound might indicate insulin resistance is less clear than the finding that it does, the researchers said. "Clinicians increasingly use these point-of-care and handheld ultrasound devices, sometimes called 'the stethoscope of the future,' for rapid diagnosis of various conditions," Soliman said. "A medical assistant or clinician with little to no training could easily use this device on a patient's upper arm or thigh, as routinely as checking weight or blood pressure, and potentially flag patients as 'high risk' or 'low risk' for further testing."
USA Today
08-02-2025
- Sport
- USA Today
How to watch Columbia Lions vs. Brown Bears: Live stream info, TV channel, game time
How to watch Columbia Lions vs. Brown Bears: Live stream info, TV channel, game time | February 8 The Columbia Lions (11-8, 0-6 Ivy League) will host the Brown Bears (10-9, 2-4 Ivy League) after dropping four home games in a row. It starts at 2:00 PM ET on Saturday, February 8, 2025. In its previous game, Columbia lost at home to Dartmouth, 95-89. Its top performers were Avery Brown (24 PTS, 2 STL, 56.25 FG%) and Zine Eddine Bedri (24 PTS, 8 REB, 62.5 FG%, 2-5 from 3PT). In its most recent game, Brown lost to Princeton, 69-49, on the road. Its top scorers were Kino Lilly Jr. (18 PTS, 42.86 FG%, 4-8 from 3PT) and Lyndel Erold (11 PTS, 2 STL, 50 FG%, 3-6 from 3PT). Ahead of this matchup, here is what you need to get ready for Saturday's college basketball action. Check out: USA TODAY Sports Coaches Poll Columbia vs. Brown: How to watch on TV or live stream Game day: Saturday, February 8, 2025 Saturday, February 8, 2025 Game time: 2:00 PM ET 2:00 PM ET Location: New York City, New York New York City, New York Arena: Francis S. Levien Gymnasium Francis S. Levien Gymnasium TV Channel: ESPN+ ESPN+ Live Stream: ESPN+ - Watch NOW Watch college basketball on ESPN+! Lions vs. Bears odds and spread Spread Favorite: Lions (-2) Lions (-2) Moneyline: Columbia (-144), Brown (+119) Columbia (-144), Brown (+119) Total: 153.5 points College basketball odds courtesy of BetMGM Sportsbook. Odds updated Friday at 9:33 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub. Watch college basketball on ESPN+!
Yahoo
07-02-2025
- Sport
- Yahoo
Columbia faces Brown following Brown's 24-point game
Brown Bears (10-9, 2-4 Ivy League) at Columbia Lions (11-8, 0-6 Ivy League) New York; Saturday, 2 p.m. EST BOTTOM LINE: Columbia hosts Brown after Avery Brown scored 24 points in Columbia's 95-89 loss to the Dartmouth Big Green. The Lions have gone 8-4 in home games. Columbia is sixth in the Ivy League in team defense, giving up 75.3 points while holding opponents to 44.5% shooting. The Bears are 2-4 against Ivy League opponents. Brown ranks fifth in the Ivy League with 22.8 defensive rebounds per game led by Aaron Cooley averaging 4.8. See for yourself — The Yodel is the go-to source for daily news, entertainment and feel-good stories. By signing up, you agree to our Terms and Privacy Policy. Columbia averages 9.3 made 3-pointers per game, 1.8 more made shots than the 7.5 per game Brown allows. Brown has shot at a 44.5% rate from the field this season, the same as opponents of Columbia have averaged. The matchup Saturday is the first meeting of the season between the two teams in conference play. TOP PERFORMERS: Geronimo Rubio De La Rosa is averaging 18 points and 1.7 steals for the Lions. Brown is averaging 13.7 points over the last 10 games. Kino Lilly Jr. is averaging 19.1 points and four assists for the Bears. Cooley is averaging 11.3 points over the last 10 games. LAST 10 GAMES: Lions: 3-7, averaging 82.6 points, 32.4 rebounds, 16.5 assists, 9.1 steals and 2.2 blocks per game while shooting 47.6% from the field. Their opponents have averaged 79.3 points per game. Bears: 4-6, averaging 71.7 points, 31.6 rebounds, 14.5 assists, 5.9 steals and 4.8 blocks per game while shooting 42.5% from the field. Their opponents have averaged 78.5 points. ___ The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.
