Latest news with #Banting
Time of India
3 days ago
- Health
- Time of India
How a 14-year-old's medical treatment in 1922 revolutionized diabetes care and led to a historic four-way Nobel Prize split
The invention of insulin in 1922 marked a turning point in medical history. Sparked by Frederick Banting's idea and tested on diabetic patients, the treatment saved lives and revolutionized diabetes care. Though the Nobel Prize honored Banting and Macleod, internal conflicts led Banting to share credit with Best and Macleod with Collip, reflecting a complex legacy. In 1922, 14-year-old Leonard Thompson became the first person to receive an insulin injection, a breakthrough that transformed diabetes from a fatal disease into a manageable condition. (Images: X/ University of Toront , iStock) Tired of too many ads? Remove Ads From Farm Boy to Medical Pioneer: Banting's Unlikely Journey Trial, Error, and Triumph: The Birth of Insulin Tired of too many ads? Remove Ads A Miracle Drug Emerges The Nobel Prize Controversy Beyond the Breakthrough In 1922, the world witnessed one of the most transformative moments in medical history. A 14-year-old boy named Leonard Thompson , lying comatose from type 1 diabetes at Toronto General Hospital , became the first human to receive an injection of insulin. That one injection, administered by Dr. Frederick Banting and medical student Charles Best, not only saved Leonard's life—giving him thirteen more years—but also turned a fatal condition into a manageable one. It marked the beginning of modern diabetes treatment, a path paved by hope, controversy, and scientific to an article from Science History Institute, Frederick Grant Banting wasn't always on the fast track to scientific fame. The youngest son of Methodist farmers from Alliston, Ontario, he almost became a minister before switching to medicine. After serving in World War I and returning with a shrapnel injury, he struggled to establish his surgical practice in London, Ontario. It was in his role as a lecturer at a medical school that a chance encounter with a medical journal sparked an idea that would later reshape an article on the pancreatic islets of Langerhans , Banting jotted down a bold idea: to isolate the internal secretions of the pancreas that controlled blood sugar. He pitched it to John Macleod, a renowned physiologist at the University of Toronto. Skeptical but intrigued, Macleod gave Banting lab space, ten dogs, and a young assistant named Charles the summer of 1921, Banting and Best began their experiments, using dogs to test how pancreatic extract could affect diabetes. Through duct ligation and pancreatectomies, they observed the remarkable effects of what they called "isletin"—soon to be renamed insulin. After refining the extract with the help of biochemist James Collip, the team tested it on Leonard the initial injection in January 1922 had minimal impact, Collip's improved purification method led to a second, far more successful attempt. Leonard's blood sugar dropped significantly, and insulin had proven its worth. This event signaled the dawn of a new era in insulin, diabetes management relied on near-starvation diets—sometimes as low as 500 calories a day. These regimens prolonged life but at a devastating cost to quality of life. Insulin changed everything. By the end of 1923, Eli Lilly had already begun mass production, and diabetic patients were regaining strength, eating balanced meals, and living fuller treatment's impact was swift and profound, and insulin became one of the 20th century's greatest medical 1923, the Nobel Committee awarded the Prize in Physiology or Medicine to Banting and Macleod. Outraged that Best wasn't recognized, Banting announced he would split his award with him. In a move that mirrored this gesture—and perhaps attempted to quell the growing tension—Macleod shared his winnings with the scenes, the collaboration was far from harmonious. Banting grew increasingly suspicious of Macleod, accusing him of seeking credit, while a heated dispute broke out between Banting and Collip over the insulin purification process. Yet, despite these personal clashes, the collective efforts of all four men changed medical story of insulin isn't just about science—it's about persistence, chance, and complex human dynamics. It traces back to 19th-century researchers like Paul Langerhans, who first identified the islets in the pancreas, and German physiologists Oskar Minkowski and Joseph von Mering, who discovered the connection between the pancreas and it was in the laboratory at the University of Toronto where all the strands finally came together. The discovery of insulin remains a striking reminder of how one idea, sparked by curiosity and followed by relentless experimentation, can rewrite the fate of millions. And it all began with one injection in 1922.
Malay Mail
7 days ago
- Malay Mail
Vocational college student killed in Banting motorcycle accident
SHAH ALAM, June 26 — A Banting Vocational College student, who was on his way home to Kanchong, Kuala Langat near here, died after falling off his motorcycle when it skidded at Kilometre 32 of Jalan Klang-Banting-Port Dickson, yesterday evening. Kuala Langat police chief Supt Mohd Akmalrizal Radzi said in the 5.10 pm incident, the 17-year-old male student suffered serious head injuries and died at the scene. Initial investigations found that the victim was riding a Yamaha Lagenda 115Z motorcycle from the direction of Telok Datok heading towards Banting when he lost control of the machine and fell, before being hit by a lorry, he said in a statement here today. He said the lorry driver, in his 50s, was not injured. The case is investigated under Section 41(1) of the Road Transport Act 1987, and those with information on the incident are urged to contact Investigating Officer Inspector Nor Baiti Mustafa at 014-5006072 to assist in the investigation. — Bernama
Malay Mail
15-05-2025
- Malay Mail
‘Brake failure' behind Banting fatal crash? Lorry driver under four-day remand over courier worker's death, cops say no prior criminal record
BANTING, May 15 — Police have remanded a lorry driver for investigation into the fatal road crash that killed a multinational courier company employee on Jalan Labohan here yesterday. Kuala Langat district police chief, Superintendent Akmalrizal Radzi, said the four-day remand order by the Telok Datok Magistrate's Court for the suspect, a man in his 30s, takes effect from today. 'Checks revealed that the suspect has no prior criminal record. The four-day remand is to facilitate further investigation,' he was quoted as saying by Utusan Malaysia. Earlier, the Malay newspaper reported that a motorcyclist was killed in a collision with a lorry along Jalan Labohan in Banting at approximately 1.30p.m May 14. The accident involved a 10-tonne lorry and a motorcycle ridden by the victim, a man in his 40s. The victim died at the scene after becoming trapped beneath the lorry. Fire and rescue personnel were called in to retrieve the body. Preliminary investigations suggest that brake failure may have caused the accident. The case is being investigated under Section 41(1) of the Road Transport Act 1987 for causing death by reckless or dangerous driving.
Malay Mail
15-05-2025
- Malay Mail
Out-of-control trailer crashes into five vehicles in front of Banting bank; no injuries reported
SHAH ALAM, May 15 — A trailer is believed to have lost control, causing a collision involving five other vehicles at KM32.5 of the Klang-Banting road, in front of a bank in Banting, yesterday. Kuala Langat police chief Supt Mohd Akmalrizal Mohd Radzi said in a statement today that all victims aged between 20 and 50 were unhurt. He said in the 12.15 pm incident, a trailer travelling from Dengkil to Sungai Buaya is believed to have crashed into another trailer, causing it to hit other vehicles that were making way for a Proton Gen2 car to park by the roadside. 'Other vehicles hit were a Proton X90, Proton Persona, Proton Gen2, and a Toyota Alphard,' he said, adding that the trailer driver, in his 40s, holds a valid driver's licence and tested negative for drugs. The case is classified under Section 43(1) of the Road Transport Act 1987 for careless and inconsiderate driving. He urged the public with information about the incident to contact the investigating officer, Inspector Mazrol Mohd Din, at 011-18539115 or 03-31872222 to assist in the investigation. — Bernama
CBC
30-01-2025
- Politics
- CBC
Thames Valley school board backtracks decision to move French immersion students to Clarke Road
The region's public school board has reversed its plan to move some French immersion students to Clarke Road Secondary School after not enough kids registered for the program along with difficulty finding teachers, CBC News has learned. The decision was made by Thames Valley District School Board (TVDSB) trustees during a meeting on Tuesday, following a discussion closed to the public. A brief note was posted to the board's website, Thursday morning, a day after officials say they notified staff and families. "There are recruiting challenges in the number of available qualified French immersion teachers, not only in Thames Valley but across the province and there's also a concern about enrolment viability," said board chair Beth Mai. "The current registration numbers at [Clarke Road] didn't meet the threshold that we would have to be able to provide a sustainable program to students over a period of years." Mai would not disclose how many students registered for the program, citing privacy concerns of the closed session discussion. Clarke Road would have been the board's sixth high school French immersion site in the region, and the third in London, in addition to existing programs at Sir Frederick Banting and Sir Wilfrid Laurier Secondary Schools. TVDSB decided to create a site at Clarke Road in the 2023-24 school year due to growth pressures and the school being one of three high schools below its optimal enrolment numbers. However, the decision received significant pushback from parents who didn't want their kids to change schools and expressed concerns during public consultations on the matter held in 2023. M.J. Kidnie has kids in Grades 9 and 11 who are in Banting's French immersion program. Although they wouldn't have been required to go to Clarke Road, she believes cancelling the new program is great news for French immersion in the city. "It became clear to me that the FI program as it exists now would be impoverished by adding another location in the city. If you don't have a fairly large cohort in Grade 9, it dwindles away and that means kids can't continue to get the French immersion courses in Grade 11 and 12," she said. "I do wish the board had listened to parents because the results they found that they didn't get students enrolled, we predicted that. We didn't know about the teacher piece but I think not listening to parents led to confusion and uncertainty." Kidnie said plans for Clarke Road also pushed some parents to proactively enrol their children into French immersion in the region's Catholic school board, which is the fastest growing in Ontario. Why are there so many non-Catholic students in London's Catholic high schools? Erma Schadenberg was one of those parents who enrolled her Grade 8 daughter at Mother Teresa Catholic Secondary (MTS) School when she graduates from Louise Arbour Public School, which typically feeds into Banting but boundary changes would have required her to go to Clarke Road. However, since the board's reversal, Schadenberg said her daughter will now go to Banting, instead of MTS, adding that it's where her daughter wanted to go all along. "I was very impressed with Mother Teresa and what they had to offer, but my daughter did choose to go back to Banting," she said. "I also have two Banting graduates so there's a bit of a family legacy that is being factored in." In a statement, TVDSB said the decision is also made in part due to the need to prioritize financial resources responsibly. It said it will concentrate French immersion resources at Banting and Laurier "ensuring they remain well-equipped and accessible."
