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AI Model Detects Early Pancreatic Cancer on CT Scans
AI Model Detects Early Pancreatic Cancer on CT Scans

Medscape

time04-07-2025

  • Health
  • Medscape

AI Model Detects Early Pancreatic Cancer on CT Scans

TOPLINE: An artificial intelligence (AI) model achieved a sensitivity of 91.8% in detecting pancreatic cancer on CT scans at diagnosis, with a 53.9% sensitivity for scans taken 1 year or more before diagnosis. The model demonstrated a sensitivity of 82.9% for stage I pancreatic cancer detection, suggesting potential for earlier diagnosis. METHODOLOGY: This analysis included 1083 patients (mean age, 68.9 years; 575 men) with biopsy-confirmed pancreatic cancer from Danish medical registries between 2006 and 2016. Researchers evaluated 1220 CT scans, including 1022 concurrent diagnosis scans acquired within 2 months of histopathologic diagnosis and 198 prediagnosis scans obtained before diagnosis (median, 7 months prior). The PANCANAI model, previously trained on 2134 portal venous CT scans, was tested for pancreatic cancer detection through lesion identification and main pancreatic duct dilation assessment. TAKEAWAY: The AI model demonstrated a high sensitivity of 91.8% (95% CI, 89.9%-93.5%) for concurrent diagnosis scans and 68.7% (95% CI, 62.1%-75.3%) for prediagnosis scans. The performance varied on the basis of the contrast phase, with sensitivities of 92.1% (95% CI, 90.3%-93.6%) for portal, 90.9% (95% CI, 83.6%-96.4%) for arterial, and 83.5% (95% CI, 70%-96.7%) for delayed phases. The model maintained effectiveness across different cancer stages, achieving sensitivities of 83.1% for stage I, 85.5% for stage II, 94.9% for stage III, and 93.0% for stage IV cases. For smaller subgroups, a sensitivity of 53.9% (95% CI, 41.8%-65.7%) was observed for CT scans acquired more than 1 year before diagnosis and 24.5% (95% CI, 6.3%-43.8%) for scans acquired more than 2 and a half years before diagnosis. IN PRACTICE: "This study showed that PANCANAI was able to detect pancreatic cancer in approximately half of the CT scans acquired more than a year before histopathologic diagnosis. This result suggests that the algorithm may enable timely diagnosis, which could drastically improve patients' survival," the authors of the study wrote. SOURCE: This study was led by Laura Degand, MSc, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. It was published online on June 24, 2025, in Investigative Radiology. LIMITATIONS: The study cohort consisted of only patients with pancreatic cancer, limiting the evaluation to sensitivity without the initial specificity assessment. Additionally, most CT scans were from patients diagnosed at stage IV or with undetermined staging, constraining the evaluation of the algorithm on early-stage cases. The researchers also noted technical limitations that prevented a proper evaluation of the model's segmentation accuracy through radiologist verification. DISCLOSURES: No funding information was provided for this study. Several authors reported receiving funding from and having other ties with various sources. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

How Much Will Medicare Cover If I Need a CT Scan?
How Much Will Medicare Cover If I Need a CT Scan?

Health Line

time02-06-2025

  • Business
  • Health Line

How Much Will Medicare Cover If I Need a CT Scan?

Key takeaways Medicare will cover any medically necessary diagnostic tests, including CT scans. Inpatient CT scans are typically covered by Part A, while outpatient CT scans are usually covered by Part B. Part C (also called Medicare Advantage) plans include at least the same level of coverage as parts A and B. Medigap plans can help decrease out-of-pocket costs associated with Original Medicare coverage for CT scans. Medicare will cover any medically necessary diagnostic tests you need. This includes computed tomography (CT) scans. Your exact coverage depends on where you have the test and which Medicare part covers it. Part A coverage for CT scans Part A is hospital insurance. It covers the care you receive during an inpatient stay at: a hospital a skilled nursing facility another inpatient facility This includes any tests your doctor orders during your stay. So, if you receive a CT scan in the hospital, Part A will cover it. In this situation, the cost of a CT scan will go toward your Part A deductible. In 2024, the Part A deductible is $1,632 for each benefit period, and in 2025, it is $1,676. Once you've met this deductible, Part A will cover all tests and procedures during your stay, with no coinsurance costs during the first 60 days of hospitalization. Part B coverage for CT scans Part B is medical insurance. It covers outpatient care at multiple types of healthcare facilities, such as: doctor's offices urgent care centers health centers outpatient clinics outpatient labs and testing facilities surgical centers Part B will cover your CT scan no matter which outpatient setting you have it in. You'll have coverage as long as the facility participates in Medicare and a doctor orders the scan. The Medicare website has a tool for checking which facilities and providers participate in Medicare in your area. After you meet your Part B deductible, Medicare will pay 80% of the approved cost of your CT scan. You'll be responsible for the other 20%. The Medicare Part B deductible is $240 in 2024 and $257 in 2025. Part C coverage for CT scans All Part C plans cover CT scans. However, many Part C plans have networks. You might pay much higher costs for leaving your plan's network. Sometimes, you may not have out-of-network coverage, even if the facility participates in Medicare. The deductible and any copayment or coinsurance amount depend on your specific plan. If possible, contact your insurance company ahead of time to get an estimate of how much this test will cost. Medigap coverage for CT scans Medigap is supplemental insurance that you can buy to cover your out-of-pocket costs from Medicare. Depending on your Medigap plan, you may be able to get coverage for your: Part A deductible Part B deductible Part A copays and coinsurance Part B copays and coinsurance That means that Medigap would cover any costs associated with your CT scan that would typically be your responsibility. Medigap plans have a monthly premium on top of your Medicare Part B premium. So, while you'll pay more each month, the costs will be covered when you need a service like a CT scan. The bottom line Part A will cover your CT scan if you have it during an inpatient hospital stay, and Part B will cover it when you have it as an outpatient. Part C will also cover a CT scan, but you'll typically need to stay within your plan's network. If Medicare doesn't cover your CT scan and you think it should, you can file an appeal. An appeal will give you several chances to explain why the CT scan was medically necessary and see whether Medicare will cover it.

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