Latest news with #CancerPreventionResearch
Time of India
2 days ago
- Health
- Time of India
Colon Cancer: US Gastroenterologist shares 6 snack ideas that can reduce colon cancer risk
Colon cancer, also known as colorectal cancer, is increasingly common, especially among younger adults. In recent years, doctors have witnessed a disturbing trend linked with colon cancer, which traditionally is viewed as a disease of older adults, but is increasingly striking people under 50. Colorectal cancer, also known as colon cancer, is a type of cancer that develops in the tissues of the colon or rectum. It's one of the most common types of cancer worldwide and the second leading cause of cancer death in the United States. Thanks to obesity and alcohol consumption, bowel cancer has become the primary cause of the rising death toll among young adults. However, early detection and lifestyle changes play crucial roles in reducing risk. According to gastroenterologists like Dr. Joseph Salhab, simple dietary tweaks, particularly smart snacking, can support colon health and lower the risk of developing this disease. How? Incorporating high-fiber, nutrient‑dense snacks into your daily routine not only promotes regular digestion but also feeds beneficial gut microbes that guard against inflammation and carcinogenic processes. Here are six science-backed snack ideas a leading gastroenterologist recommends to help reduce colon cancer risk. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Young Woman (19) Lives in a Shed - Take a look inside Tips and Tricks Undo Yogurt Yogurt, known as the probiotic powerhouse, is rich in live probiotics like Lactobacillus and Bifidobacterium, which support a balanced gut microbiome. A meta-analysis reveals that higher yogurt consumption correlates with a 7% reduction in colorectal cancer risk. The lactic acid bacteria in yogurt may produce antioxidant, anti-inflammatory, and immunomodulatory effects. For snack ideas, try Greek yogurt with fresh berries or yogurt parfaits topped with granola. These snacks are as nourishing and gut-friendly as they're tasty! Tree nuts Tree nuts like almonds, cashews, Brazil nuts, more particularly, walnuts offer fiber, healthy fats, and plant compounds like ellagitannins. One clinical trial (published earlier this year in Cancer Prevention Research ) showed 28 g of walnuts daily reduced inflammation markers and vimentin levels, proteins tied to aggressive colon tumors. Furthermore, as Dr. Salhab references, in stage III colon cancer patients, research shows, eating two servings of tree nuts daily reduced disease recurrence by 42%. Aim for a daily nut handful or mix walnuts into trail mix or oatmeal for an antioxidant boost. Apples An apple a day might even keep the big C (cancer) at bay. Apples, especially with their skin, offer soluble and insoluble fiber plus flavonoids. One case–control study linked consuming at least one apple daily to a 47% lower risk of colorectal cancer. Fiber aids bowel regularity and toxin removal, while phytonutrients support gut health. Snack on apple slices with almond butter or part of a lunch fruit salad. Citrus fruits Hydrating and fiber‑rich citrus fruits, like oranges, grapefruits, and clementines, are not only high in fiber, but their water content, vitamins, and bioactive compounds also add to their numerous health benefits. A study, published in Nature , shows citrus intake may decrease colorectal cancer risk by up to 18%. The combination of antioxidants, fiber, and hydration supports digestion and reduces carcinogen exposure in the colon. Moreover, you can enjoy them fresh, in smoothies, or sprinkled in salads. Watermelon Made of over 90% water, watermelon aids hydration and regular digestion. This luscious fruit is not only crucial for colon health, but the lycopene and antioxidants in watermelon contribute anti-inflammatory benefits, slashing the risk of colorectal cancer considerably. What's more? Fresh watermelon slices or blended into agua fresca are a refreshing addition to your daily diet. Salsa and guacamole This one, we hardly see it coming! Tomato-based salsa provides lycopene and fiber, while avocado adds monounsaturated fats, fiber (about 10 g per medium avocado), and antioxidants. Mix them together for a gut‑health powerhouse . As per research, superfruit avocado consumption has been shown to lower colon cancer risk. Moreover, tomatoes and avocados together offer synergistic benefits. So, spruce up your snacking habit using these as dips for whole‑grain crackers or chopped vegetables. The information provided in this story is intended for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making changes to your diet, undergoing cancer screenings, or adopting any preventive strategies. If you have symptoms (e.g., rectal bleeding, persistent abdominal pain) or a family history of colon cancer, seek medical evaluation promptly. Study shows new links between high fat diets, colon cancer
The Print
24-05-2025
- Health
- The Print
Research Investigates Walnuts' Role in Reducing Inflammation and Colon Cancer Risk
New Delhi [India], May 23: New findings published in Cancer Prevention Research show daily walnut consumption may improve markers of systemic inflammation and reduce colon cancer risk. Colon cancer is one of the most common cancers worldwide and accounts for around 10% of total cancer diagnoses.1 Urolithin A (UA), a metabolic byproduct of the plant-derived polyphenols, ellagitannins, found in walnuts, are thought to contribute to these findings. Researchers at the University of Connecticut analyzed the impact of 56g of daily walnut consumption among 39 healthy adult participants, age 50-65, on urinary urolithins and markers of inflammation, immunity and other indicators of colonic health for three weeks prior to undergoing a routine colonoscopy. 2 This clinical trial followed a preclinical study by Dr. Masako Nakanishi, an investigator in the Rosenberg lab, who first reported on these effects of walnut consumption on colon cancer. 3 In the present study, researchers found that consuming a walnut-containing diet resulted in increased urinary UA levels which were linked to lower levels of several inflammatory markers present in the blood. In addition, the study found changes in colon polyps that could ultimately prove to be beneficial for preventing the development of some cancers. Urolithins have been studied for their anti-inflammatory properties and may play a role in cancer prevention. 4,5 It is thought that higher levels of urinary UA could be responsible for these changes that were observed in polyp tissues, even after a short exposure interval to walnuts. Dr. Daniel W. Rosenberg, the HealthNet Chair in Cancer Biology and an investigator at the Center for Molecular Oncology at the University of Connecticut School of Medicine, has been studying the properties of walnuts and their anti-inflammatory benefits for more than a decade. 'Walnuts are an exceptional source of health-promoting nutrients called ellagitannins. These nutrients, when broken down by the gut microbiome to form urolithin A, are thought to reduce inflammation and may be responsible for reducing risk of colon cancer,' notes Rosenberg. Beyond their ellagitannin content, walnuts are known for their nutrient composition. Walnuts are the only nut to provide an excellent source of omega-3 ALA (2.5g/28g), which has been researched to support brain health, heart health and more.6 Walnuts also provide 4 grams of plant-based protein along with a variety of other nutrients in just one handful.7 'This study adds to the growing body of evidence supporting walnuts as a functional food with benefits that go beyond basic nutrition. The ability of walnuts to produce urolithin A — a compound linked to reduced inflammation and potential protection against colon cancer — makes them especially relevant today, as more Indians face digestive health challenges linked to modern diets and lifestyles. Including a handful of walnuts daily is a simple, effective habit that can support gut health and contribute to overall wellness,' states Naaznin Husein, Member of the Indian Dietetic Association. Reaping the health benefits of walnuts is as easy as incorporating a handful into your meals and snacks. Try some of these recipes to add California walnuts: * At breakfast, try this tropical mango smoothie bowl * Snack on these California walnut ladoos or smoked spiced California walnuts * Make a batch of these California walnut kebabs for dinner More research is needed as this was a relatively small and short-term study and it is unclear whether the observed effects of consuming walnuts would persist over a longer period of time or in a larger population. Additionally, the study was not a randomized control trial. For more information on the role of walnuts in cancer prevention and gut health or recipe ideas, please visit The California Walnut Commission (CWC) represents more than 3,700 California walnut growers and approximately 70 handlers, grown in multi-generational farmers' family orchards. California walnuts, known for their excellent nutritional value and quality, are shipped around the world all year long, with more than 99% of the walnuts grown in the United States being from California. The CWC, established in 1987, promotes usage of walnuts through domestic and export market development activities as well as supports health research with consuming walnuts. References: 1. World Health Organization. Colorectal cancer. World Health Organization website. Accessed May 2, 2025. Updated July 11, 2023. 2. Moussa MR, Fan N, Birk J, et al. Systemic inflammation and the inflammatory context of the colonic microenvironment are improved by urolithin A. Cancer Prev Res (Phila). 2025;18(4):235-50. 3. Nakanishi M, Chen Y, Qendro V, et al. Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure. Cancer Prev Res (Phila). 2016 Aug;9(8):692-703. doi: 10.1158/ 4. Fan N, Fusco JL, Rosenberg DW. Antioxidant and anti-inflammatory properties of walnut constituents: Focus on personalized cancer prevention and the microbiome. Antioxidants. 2023;12(5):982. 5. Mandalari G, Gervasi T, Rosenberg DW, Lapsley KG, Baer DJ. Effect of nuts on gastrointestinal health. Nutrients. 2023;15(7):1733. 6. Sala-Vila A, Fleming J, Kris-Etherton P, Ros E. Impact of alpha-linolenic acid, the vegetable omega-3 fatty acid, on cardiovascular disease and cognition [published ahead of print February 16, 2022]. Advances in Nutrition. 7. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central, 2019. (ADVERTORIAL DISCLAIMER: The above press release has been provided by NewsVoir. ANI will not be responsible in any way for the content of the same) This story is auto-generated from a syndicated feed. ThePrint holds no responsibility for its content.
Business Standard
23-05-2025
- Health
- Business Standard
Research Investigates Walnuts' Role in Reducing Inflammation and Colon Cancer Risk
NewsVoir New Delhi [India], May 23: New findings published in Cancer Prevention Research show daily walnut consumption may improve markers of systemic inflammation and reduce colon cancer risk. Colon cancer is one of the most common cancers worldwide and accounts for around 10% of total cancer diagnoses.1 Urolithin A (UA), a metabolic byproduct of the plant-derived polyphenols, ellagitannins, found in walnuts, are thought to contribute to these findings. Researchers at the University of Connecticut analyzed the impact of 56g of daily walnut consumption among 39 healthy adult participants, age 50-65, on urinary urolithins and markers of inflammation, immunity and other indicators of colonic health for three weeks prior to undergoing a routine colonoscopy. 2 This clinical trial followed a preclinical study by Dr. Masako Nakanishi, an investigator in the Rosenberg lab, who first reported on these effects of walnut consumption on colon cancer. 3 In the present study, researchers found that consuming a walnut-containing diet resulted in increased urinary UA levels which were linked to lower levels of several inflammatory markers present in the blood. In addition, the study found changes in colon polyps that could ultimately prove to be beneficial for preventing the development of some cancers. Urolithins have been studied for their anti-inflammatory properties and may play a role in cancer prevention. 4,5 It is thought that higher levels of urinary UA could be responsible for these changes that were observed in polyp tissues, even after a short exposure interval to walnuts. Dr. Daniel W. Rosenberg, the HealthNet Chair in Cancer Biology and an investigator at the Center for Molecular Oncology at the University of Connecticut School of Medicine, has been studying the properties of walnuts and their anti-inflammatory benefits for more than a decade. "Walnuts are an exceptional source of health-promoting nutrients called ellagitannins. These nutrients, when broken down by the gut microbiome to form urolithin A, are thought to reduce inflammation and may be responsible for reducing risk of colon cancer," notes Rosenberg. Beyond their ellagitannin content, walnuts are known for their nutrient composition. Walnuts are the only nut to provide an excellent source of omega-3 ALA (2.5g/28g), which has been researched to support brain health, heart health and more.6 Walnuts also provide 4 grams of plant-based protein along with a variety of other nutrients in just one handful.7 "This study adds to the growing body of evidence supporting walnuts as a functional food with benefits that go beyond basic nutrition. The ability of walnuts to produce urolithin A -- a compound linked to reduced inflammation and potential protection against colon cancer -- makes them especially relevant today, as more Indians face digestive health challenges linked to modern diets and lifestyles. Including a handful of walnuts daily is a simple, effective habit that can support gut health and contribute to overall wellness," states Naaznin Husein, Member of the Indian Dietetic Association. Reaping the health benefits of walnuts is as easy as incorporating a handful into your meals and snacks. Try some of these recipes to add California walnuts: * At breakfast, try this tropical mango smoothie bowl * Snack on these California walnut ladoos or smoked spiced California walnuts * Make a batch of these California walnut kebabs for dinner More research is needed as this was a relatively small and short-term study and it is unclear whether the observed effects of consuming walnuts would persist over a longer period of time or in a larger population. Additionally, the study was not a randomized control trial. For more information on the role of walnuts in cancer prevention and gut health or recipe ideas, please visit The California Walnut Commission (CWC) represents more than 3,700 California walnut growers and approximately 70 handlers, grown in multi-generational farmers' family orchards. California walnuts, known for their excellent nutritional value and quality, are shipped around the world all year long, with more than 99% of the walnuts grown in the United States being from California. The CWC, established in 1987, promotes usage of walnuts through domestic and export market development activities as well as supports health research with consuming walnuts. References: 1. World Health Organization. Colorectal cancer. World Health Organization website. Accessed May 2, 2025. Updated July 11, 2023. 2. Moussa MR, Fan N, Birk J, et al. Systemic inflammation and the inflammatory context of the colonic microenvironment are improved by urolithin A. Cancer Prev Res (Phila). 2025;18(4):235-50. 3. Nakanishi M, Chen Y, Qendro V, et al. Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure. Cancer Prev Res (Phila). 2016 Aug;9(8):692-703. doi: 10.1158/ 4. Fan N, Fusco JL, Rosenberg DW. Antioxidant and anti-inflammatory properties of walnut constituents: Focus on personalized cancer prevention and the microbiome. Antioxidants. 2023;12(5):982. 5. Mandalari G, Gervasi T, Rosenberg DW, Lapsley KG, Baer DJ. Effect of nuts on gastrointestinal health. Nutrients. 2023;15(7):1733. 6. Sala-Vila A, Fleming J, Kris-Etherton P, Ros E. Impact of alpha-linolenic acid, the vegetable omega-3 fatty acid, on cardiovascular disease and cognition [published ahead of print February 16, 2022]. Advances in Nutrition. 7. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central, 2019.
Fashion Value Chain
23-05-2025
- Health
- Fashion Value Chain
Research Investigates Walnuts' Role in Reducing Inflammation and Colon Cancer Risk
New findings published in Cancer Prevention Research show daily walnut consumption may improve markers of systemic inflammation and reduce colon cancer risk. Colon cancer is one of the most common cancers worldwide and accounts for around 10% of total cancer diagnoses.1 Urolithin A (UA), a metabolic byproduct of the plant-derived polyphenols, ellagitannins, found in walnuts, are thought to contribute to these findings. California walnuts Researchers at the University of Connecticut analyzed the impact of 56g of daily walnut consumption among 39 healthy adult participants, age 50-65, on urinary urolithins and markers of inflammation, immunity and other indicators of colonic health for three weeks prior to undergoing a routine colonoscopy.2 This clinical trial followed a preclinical study by Dr. Masako Nakanishi, an investigator in the Rosenberg lab, who first reported on these effects of walnut consumption on colon cancer.3 In the present study, researchers found that consuming a walnut-containing diet resulted in increased urinary UA levels which were linked to lower levels of several inflammatory markers present in the blood. In addition, the study found changes in colon polyps that could ultimately prove to be beneficial for preventing the development of some cancers. Urolithins have been studied for their anti-inflammatory properties and may play a role in cancer prevention.4,5 It is thought that higher levels of urinary UA could be responsible for these changes that were observed in polyp tissues, even after a short exposure interval to walnuts. A handful of California walnuts Dr. Daniel W. Rosenberg, the HealthNet Chair in Cancer Biology and an investigator at the Center for Molecular Oncology at the University of Connecticut School of Medicine, has been studying the properties of walnuts and their anti-inflammatory benefits for more than a decade. 'Walnuts are an exceptional source of health-promoting nutrients called ellagitannins. These nutrients, when broken down by the gut microbiome to form urolithin A, are thought to reduce inflammation and may be responsible for reducing risk of colon cancer,' notes Rosenberg. Beyond their ellagitannin content, walnuts are known for their nutrient composition. Walnuts are the only nut to provide an excellent source of omega-3 ALA (2.5g/28g), which has been researched to support brain health, heart health and more.6 Walnuts also provide 4 grams of plant-based protein along with a variety of other nutrients in just one handful.7 'This study adds to the growing body of evidence supporting walnuts as a functional food with benefits that go beyond basic nutrition. The ability of walnuts to produce urolithin A – a compound linked to reduced inflammation and potential protection against colon cancer – makes them especially relevant today, as more Indians face digestive health challenges linked to modern diets and lifestyles. Including a handful of walnuts daily is a simple, effective habit that can support gut health and contribute to overall wellness,' states Naaznin Husein, Member of the Indian Dietetic Association. Reaping the health benefits of walnuts is as easy as incorporating a handful into your meals and snacks. Try some of these recipes to add California walnuts: More research is needed as this was a relatively small and short-term study and it is unclear whether the observed effects of consuming walnuts would persist over a longer period of time or in a larger population. Additionally, the study was not a randomized control trial. For more information on the role of walnuts in cancer prevention and gut health or recipe ideas, please visit About the California Walnut Commission The California Walnut Commission (CWC) represents more than 3,700 California walnut growers and approximately 70 handlers, grown in multi-generational farmers' family orchards. California walnuts, known for their excellent nutritional value and quality, are shipped around the world all year long, with more than 99% of the walnuts grown in the United States being from California. The CWC, established in 1987, promotes usage of walnuts through domestic and export market development activities as well as supports health research with consuming walnuts. References: World Health Organization. Colorectal cancer. World Health Organization website. Accessed May 2, 2025. Updated July 11, 2023. Moussa MR, Fan N, Birk J, et al. Systemic inflammation and the inflammatory context of the colonic microenvironment are improved by urolithin A. Cancer Prev Res (Phila). 2025;18(4):235-50. Nakanishi M, Chen Y, Qendro V, et al. Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure. Cancer Prev Res (Phila). 2016 Aug;9(8):692-703. doi: 10.1158/ Fan N, Fusco JL, Rosenberg DW. Antioxidant and anti-inflammatory properties of walnut constituents: Focus on personalized cancer prevention and the microbiome. Antioxidants. 2023;12(5):982. Mandalari G, Gervasi T, Rosenberg DW, Lapsley KG, Baer DJ. Effect of nuts on gastrointestinal health. Nutrients. 2023;15(7):1733. Sala-Vila A, Fleming J, Kris-Etherton P, Ros E. Impact of alpha-linolenic acid, the vegetable omega-3 fatty acid, on cardiovascular disease and cognition [published ahead of print February 16, 2022]. Advances in Nutrition. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central, 2019.
Yahoo
05-05-2025
- Health
- Yahoo
Eating a handful of walnuts every day 'reduces risk of bowel cancer'
Eating a handful of walnuts every day can 'reduce the risk of bowel cancer', according to new research. The edible seeds of walnut trees are said to provide 'long-term' health benefits, and can also curb inflammation, say American scientists. The findings come from a University of Connecticut School of Medicine clinical trial, published in the journal Cancer Prevention Research. Study leader Professor Daniel Rosenberg explained that ellagitannins, plant-derived polyphenol compounds found in walnuts, are shown to be metabolised exclusively by the gut microbiome into a range of anti-inflammatory molecules called urolithins. READ MORE: Reducing intake of one beverage can lower dementia risk - and it's not coffee READ MORE: Sunbed addict, 21, was told he could have 'a year to live' Prof Rosenberg says those urolithins are associated with "very potent" anti-inflammatory properties and may even prevent cancer. 'Ellagitannins in the walnut are importantly providing the anti-inflammatory and anti-cancer properties that we're seeing in patients in our clinical trial research, particularly the gut's conversion of ellagitannins to a potent anti-inflammatory agent, urolithin A," the scientist explained. Prof Rosenberg has studied walnuts for more than a decade and has researched the connection between walnut consumption and its anti-inflammatory purposes. The findings of the clinical trial show that high levels of urolithin A formation by the gut microbiome from walnut consumption has a "positive" impact on reducing inflammatory markers across blood, urine, and faecal samples, and may even positively affect the immune cells within colon polyps. The clinical trial involved patients between the ages of 40 and 65 and those at an elevated risk of bowel cancer, also known as colon cancer. Each of the 39 participants were asked to avoid all ellagitannin-containing foods and drinks for a week to set their urolithin levels at or close to zero before they began consuming ellagitannin-rich walnuts as part of their closely monitored diet. At the end of the three-week study, all participants underwent a high-definition colonoscopy . The research team found that elevated urolithin A levels in the urine of patients correlated with the serum levels of peptide YY, an interesting protein that has been associated with inhibition of bowel cancer. Reduced levels of several inflammation markers present in the blood were also found, especially in obese patients that had the greatest capacity to form urolithins by their gut microbiome. Prof Rosenberg also used high-dimensional spatial imaging technology that allowed the research team to develop a detailed view of the direct cellular interactions present inside colon polyps that were removed during colonoscopy at the end of the walnut study. The cutting-edge advanced imaging technology revealed that patients with high levels of urolithin A formation following walnut consumption was "directly associated" with reduced levels of several important proteins that are often present in polyps, showing for the first time how eating walnuts may directly improve bowel health. The research team also discovered that the protein vimentin - often associated with more advanced forms of colon cancer - was greatly reduced inside polyp tissues obtained from patients who had also formed the highest levels of urolithin A by their gut microbiome. The findings build on earlier work by Dr Masako Nakanishi, an Assistant Professor in Prof Rosenberg's lab, who showed in several earlier publications that walnuts had beneficial and anti-cancer effects in the colons of cancer-prone mice.
