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Roscommon bichon among finalists in Nose of Tralee competition
Roscommon bichon among finalists in Nose of Tralee competition

Irish Independent

time2 days ago

  • Entertainment
  • Irish Independent

Roscommon bichon among finalists in Nose of Tralee competition

Bailey, owned by Roscommon native Ciara Kelly, is among 31 cats and dogs to feature in twelfth annual Nose of Tralee. 'Even on our toughest days, Bailey always brings a smile to our face. He is the most friendly and lovable dog,' said his owner, who works as a pharmacy technician. The winner of the 2025 Nose of Tralee will be announced online on Tuesday, August 19 and will receive a hotel stay, a Pet Sitters Ireland voucher, a photo shoot and many other prizes. Voting begins online on Thursday, July 24 and ends on Monday, August 18 at 5pm.

Ciara Kelly and Shane Coleman excel at jaded on-air grumbling
Ciara Kelly and Shane Coleman excel at jaded on-air grumbling

Irish Times

time27-06-2025

  • Politics
  • Irish Times

Ciara Kelly and Shane Coleman excel at jaded on-air grumbling

It's a tried-and-trusted routine, one that has grown familiar to listeners down the years. The despairing observation that the country is going to the dogs, accompanied by a weary sigh and an invitation for those tuning in to share their views on the matter. In a week when Joe Duffy , that great conductor of complaints, exits the airwaves, radio aficionados of an Eeyore-ish disposition will be reassured that Newstalk Breakfast (weekdays) still serves as a reliable source for jaded grumbling. It's a tribute of sorts to Duffy that it takes two people to match his prowess in this department, with the morning show's presenters, Shane Coleman and Ciara Kelly, acting as a tag team when it comes to generating on-air glumness. On Monday Coleman gamely steps up, bemoaning the number of no-shows at driving tests as an example of Ireland's lack of civic pride. 'We're really selfish,' he laments. READ MORE His cohost suggests this may be a common trait elsewhere, too. 'It's probably all people,' Coleman concedes, 'but I think we're pretty high up that league.' Kelly, taking on the role of patriotic booster, points to the fabled generosity of Irish people, but Coleman is having none of it. 'I think we've zero sense of civic duty,' he concludes, in a headmasterly tone of disappointment rather than anger. Duffy may be retiring, but Coleman merely sounds resigned. In the Newstalk duo's defence, their show's template obliges one of them to adopt a half-empty stance during their daily riffs on topical subjects. Still, Coleman sounds authentically cheesed off at what he perceives as endemic gaming of the system here. In contrast, Kelly sounds fired up by Wednesday's news that Women's Aid last year received the highest number of domestic-abuse disclosures in its history. While rightly disturbed by the volume of abuse reports, she also sees the alarming increase as evidence of a shift in Irish society. 'I think what women are willing to accept and what women identify as abuse has changed,' says Kelly, adding that things such as pushing and shoving were minimised in the past, as was emotional abuse. Not that Coleman and Kelly are always huffing despondently or opining defiantly. For the most part they're busy with interviews and analysis of various stripes. So Tuesday's programme features the veteran PR consultant Terry Prone extolling the virtues of Botox and the former Israeli peace negotiator Daniel Levy analysing the Israel-Iran conflict: 'Israel is the most radicalising and destabilising force in the region.' Similarly, Wednesday has Coleman gleefully talking to the former Formula One engineer Bernie Collins about speedy cars, while Kelly hears Minister for Transport Darragh O'Brien discuss slow infrastructure projects. 'The pace of delivery is something we have to catch up with, and I believe we will,' says the Minister with the same Micawberish confidence he brought to the housing brief. At least someone on the show sounds optimistic, however irrationally. [ Formula One's Bernie Collins: 'People in the pub will say 'that's an unusual role for a girl'' Opens in new window ] Over on Liveline (RTÉ Radio 1, weekdays), the underlying mood is uncharacteristically celebratory, as Duffy spends his final week in the hot seat of the phone-in show. (This column goes to press before he broadcasts his farewell show, on Friday.) True, the host largely mutes his festive urges as he listens to callers recounting their collisions with e-scooters being driven on pavements, and even being punched by the drivers of said vehicles. The show must go on. But Duffy really hits his stride, albeit in emotive form, when he devotes Wednesday's programme to the devastating 1972 fire at the Noyeks timber showroom on Parnell Street in Dublin, which left eight people dead. Survivors and witnesses recall the tragedy, among them Geoff Peat, who weeps freely as he recalls his rescue efforts in the burning building. It's an often heart-wrenching item: one caller recounts the marks on windows where victims had thrown typewriters in an effort to escape the blaze. But the collective act of remembrance also seems to have an oddly cathartic effect on Duffy's contributors. Liveline has increasingly relied on nostalgic items in recent times – a sure-fire pointer to an older listenership – but in this case it's impossible not to be moved. The host appears in his element, too, his palpable sympathy notwithstanding. Meanwhile, callers offer their good wishes on Duffy's impending retirement. Mark, an Elvis impersonator, delivers a particularly memorable tribute. 'Liveline without Joe Duffy will be like Vegas without Elvis, the Vatican without the holy father, the Late Late without Gaybo.' The pernickety among us may note that The Late Late Show has been soldiering on without Gay Byrne for as long as Duffy has been hosting Liveline, but the point is well made. Joe will be a tough act to follow. Some other veteran broadcasters show no signs of slowing down. Pat Kenny (Newstalk, weekdays) remains a conspicuously vigorous presence behind the mic, throwing himself into topics great and small with equal alacrity. So while one expects him to be well briefed when discussing Nato conferences or interviewing Brendan Gleeson, it's gratifying to hear the host apply the same standards to less obviously engaging items, such as the labelling of food products. On Wednesday Kenny examines efforts in the European Parliament to restrict vegan and vegetarian food producers from using terms such as burger and sausage. Or, as Denis Drennan of the Irish Creamery Milk Suppliers Association puts it, 'hijacking or piggybacking on top of the names that are well established'. Drennan, whose stated target is multinational food companies, approvingly compares the move to regulations preventing plant-based juices being labelled as milk: 'I don't see any mammary glands on oats.' Kenny pushes back. 'Doesn't the use of language change?' he asks before examining the etymological origins of the hamburger in exacting detail. His guest sticks to his guns: 'We should put the correct label on the foods, so the consumer is well aware of what they're buying.' (By the same measure, meat might be accurately labelled 'dead animal'.) At the same time, Kenny gets caught up in the minutiae of his own ruminations to glorious effect, suggesting that offending terms such as veggie sausage could be replaced by, ahem, 'vegan cylinder'. As long as he's in this idiosyncratically inspired form, one hopes that Kenny will stick around for a long time yet. Moment of the Week Jonathan Healy, an experienced current-affairs presenter, is a natural guest host of The Hard Shoulder (Newstalk, weekdays), sounding comfortable when discussing the aftermath of the US bombing of Iran with the journalist Alistair Bunkall. So as reports emerge that Iran has retaliated by firing missiles at Qatar and Bahrain – the latter state later transpires not to have been targeted – it's surprising to hear the usually accomplished Healy make a basic error as he comments on the news: 'This is an Arab country attacking two other Arab countries.' His guest is too polite to point out that the Farsi-speaking descendants of the Persian empire are not, in fact, Arabs.

Curadev Expands Strategic Collaboration for CRD3874-SI Through MSK Therapeutics Accelerator Program
Curadev Expands Strategic Collaboration for CRD3874-SI Through MSK Therapeutics Accelerator Program

Cision Canada

time10-06-2025

  • Business
  • Cision Canada

Curadev Expands Strategic Collaboration for CRD3874-SI Through MSK Therapeutics Accelerator Program

BOSTON, June 10, 2025 /CNW/ -- Curadev Pharma, Inc., a clinical-stage biotechnology company developing novel immuno-oncology therapeutics, and Memorial Sloan Kettering Cancer Center (MSK), a world-leading cancer research and treatment institution, are expanding their collaboration through the MSK Therapeutics Accelerator program to advance the development of Curadev's small-molecule allosteric Stimulator of Interferon Genes (STING) agonist, CRD3874-SI, to be delivered systemically to patients with advanced/metastatic cancer. The collaboration builds on the ongoing Phase 1a/b dose escalation and expansion clinical trial (NCT06021626) currently underway at MSK for sarcoma and Merkel cell carcinoma patients, and aims to explore the potential of CRD3874-SI in treating additional types of cancer. Through the MSK Therapeutics Accelerator program, MSK will provide Curadev with expertise and institutional resources, including medical, clinical, and regulatory advice, to further the development of CRD3874-SI. This expanded collaboration marks a significant milestone in translating promising STING pathway research into broader clinical application and will be overseen by William Tap, MD, Chief of the Sarcoma Medical Oncology Service at MSK, and Ciara Kelly, MBBCh BAO, Interim Clinical Director of MSK's Sarcoma Oncology Service. Dr. William Tap said, "MSK and its Division of Solid Tumors are excited to co-develop CRD3874-SI, a novel first-in-class allosteric STING agonist, with Curadev. CRD3874-SI has demonstrated an encouraging safety and efficacy profile in a first-in-human study at MSK. CRD3874-SI is moving forward into multiple solid-tumor expansion cohorts, guided by disease specific experts and the support and structure of the MSK Accelerator Program, which is designed to enhance and expedite the development of novel compounds across malignancies. CRD3874-SI has the potential to offer patients a new treatment option with continued innovation and exploration of the benefits of immunotherapy in cancer care." Dr. Arjun Surya, Co-founder and CEO of Curadev, added, "We are encouraged by the early readouts with CRD3874-SI systemic monotherapy from our ongoing clinical trial in patients with treatment refractory cancers at MSK and are honored by the opportunity to deepen our collaboration through the MSK Therapeutics Accelerator program. The research and development collaboration between oncologists at MSK and the inventors of CRD3874-SI at Curadev could become a role model for advancing bench to bedside medicines. MSK's historic leadership position in the development of cancer immunotherapy and the exemplary dedication of the oncologists we work with is inspiring and make it an ideal partner in Curadev's effort to investigate the therapeutic potential of its systemically administered allosteric STING agonist in patients with advanced/metastatic cancer." About Curadev Curadev is a clinical-stage biotechnology company dedicated to discovering and developing novel small-molecule therapeutics for treating intractable diseases. Curadev has built an impressive portfolio of discovery research programs using a target-centric approach, innovative screening schemes, and traditional wet-lab chemistry and pharmacology, resulting in patent-protected drug candidates that modulate next-generation drug targets. Curadev Pharma, Inc., the US-based clinical development subsidiary founded in 2021, is currently leading the Phase1/2 trials of STING agonist assets under a US FDA-approved IND application. For more information, visit MSK's Therapeutics Accelerator program is a strategic partnership program between MSK and biotechnology companies to advance novel cancer therapeutics through all stages of drug development. The program brings together innovative healthcare companies with MSK's community of clinical and scientific experts to establish groundbreaking collaborations that can have a tangible impact on the treatment or management of cancer.

Newstalk host Ciara Kelly says she 'regrets' not taking husband's surname after marrying
Newstalk host Ciara Kelly says she 'regrets' not taking husband's surname after marrying

Sunday World

time29-05-2025

  • Entertainment
  • Sunday World

Newstalk host Ciara Kelly says she 'regrets' not taking husband's surname after marrying

'I do think that if my husband had had a cooler name, I might have been slightly more tempted.' Newstalk host Ciara Kelly has said she 'regrets' not taking her husband's surname after they got married. 'I do have some regrets about having no name connection to my children,' she explained on this morning's breakfast show. 'Should they have been double-barrelled? I don't know. 'Or should I have given them Kelly as their second name? I don't know is the answer to that,' she continued. Ciara Kelly. Photo: Evan Doherty News in 90 Seconds - May 29th Kelly said if her husband had a 'cooler name' she 'might have been slightly more tempted.' 'I think there is fashion at play here; when I was young and getting married, none of my pals in college took their husbands' names. 'Most of my pals from school who didn't go to college did. 'So, there was different cohorts of people doing different things, and I think that's still true today,' she said. 'I also do think, as someone who didn't take their husband's name and I now have a different name to all four of my children, that I didn't give it enough thought. 'I didn't want to double barrel my name, I always thought that was for gits - that's what I actually thought.' Her co-host Shane Coleman said he would have been 'a little bit disappointed' if his wife had taken his surname. 'I married Ev Conroy, I didn't marry Ev Coleman,' he said. 'We get texts from people saying, 'Oh, it's really difficult travelling', it isn't. 'Or that it's 'really confusing in school', I think people are capable of differentiating. 'There's no issue.' Read more Man (20s) charged after Garda seriously injured by stolen motorbike in Finglas It comes following the publication of an Irish Times opinion piece lamenting whether or not women should change their surname after getting married. According to Pew Research Centre, 79% of women in opposite sex marriages took their husbands' surname after they wed. While just 5% of men in opposite sex marriages took their wives' surname.

Could former GP Ciara be just what the doctor ordered for Liveline?
Could former GP Ciara be just what the doctor ordered for Liveline?

Extra.ie​

time25-05-2025

  • Entertainment
  • Extra.ie​

Could former GP Ciara be just what the doctor ordered for Liveline?

Liveline contender Ciara Kelly has highlighted her credentials in the race to replace Joe Duffy – but knows the veteran broadcaster will be an 'extremely hard act to follow'. The Newstalk Breakfast host is one of several names in the running to take the Liveline hot seat when Duffy departs on the last Friday of June. Asked about the prospect of going solo after five years presenting as a duo with Shane Coleman, Kelly pointed out she did three years on Lunchtime Live – 'the Newstalk equivalent' to Liveline – before taking the morning slot. Liveline contender Ciara Kelly has highlighted her credentials in the race to replace Joe Duffy – but knows the veteran broadcaster will be an 'extremely hard act to follow'. Pic: Gareth Chaney/ Collins Photos The former GP told 'I did the first ever interactive radio show on Newstalk. I took over from George Hook in that slot and grew the audience very nicely. So yes, I did do that role, and it went well actually.' Remaining coy as to whether she has been approached by RTÉ, the former Operation Transformation contributor said she 'couldn't possibly say anything about any of that'. 'I'm sure Liveline would be an amazing job for anyone who was lucky enough to get it. But I have no real comment other than that, obviously, I have a great job [at Newstalk] myself as well.' Further pressed on her suitability, Kelly noted: 'I suppose I do like talking to people and all of that kind of thing, absolutely. 'But having said that, I have no idea if I'm in the running for Liveline or not. That obviously is out of my hands entirely.' The GP-turned-broadcaster acknowledged that Duffy will be 'an extremely hard act to follow' for whoever ends up in his chair, after his 27 years fronting the show. Pic: RTÉ The GP-turned-broadcaster acknowledged that Duffy will be 'an extremely hard act to follow' for whoever ends up in his chair, after his 27 years fronting the show. 'And he's a lovely man,' she added. 'I would know Joe a little bit, and he's obviously an icon as well, and made [Liveline] his own. So I think for anyone filling those shoes, it would be an enormous task.' The Greystones, Co. Wicklow-raised presenter said she has been a Liveline listener, since 'even before Joe's days', when the show was hosted by the late Marian Finucane, whom Kelly described as 'probably the best broadcaster Ireland has ever produced'. 'I think Marian was gifted in her touch, not only in current affairs but in her ability to get people to open up to her and to talk to her,' Kelly said. 'And I think that's something that she shares with Joe, actually – that people saw both of them as almost like a friend, someone you could really talk to.' Kelly has worked on RTÉ TV shows before, including as a medical expert on Operation Transformation and presenting duties on the magazine's health show, Doctors On Call. (Ciara Kelly on Operation Transformation). Pic: Gareth Chaney Collins The Newstalk woman called the 40-year-old RTÉ staple Liveline 'an institution of Irish radio' that has 'a finger on the pulse of the country'. Kelly has worked on RTÉ TV shows before, including in her role as medical expert on Operation Transformation and presenting duties on the magazine health show Doctors On Call. She is a former client of Noel Kelly, the agent whose books include much of RTÉ's top talent, and who became a household name himself during the secret payments scandal in 2023. She was one of several stars to part company with NK Management in the wake of that story, citing her duty as a broadcaster to report on it without bias. Kelly told the Irish Independent in July 2023: 'In order to fully interrogate the RTÉ payments issue going forward, to remain impartial and fulfil my objective public service broadcasting remit. 'I believe I have to now step away from the agency and as of today, I no longer retain them as my agent.' Kelly's Newstalk colleague Andrea Gilligan has also been mentioned as a potential replacement for Duffy. The Donegal woman is the current presenter of Lunchtime Live – similar in format to Liveline – and has been praised for her easy manner with callers. Katie Hannon and Philip Boucher-Hayes, who have often stood in for Duffy over the years, have also been mooted as obvious considerations for RTÉ. Rose of Tralee host Dáithí Ó Sé is reportedly a strong contender too, while Dancing With The Stars presenter Jennifer Zamparelli was the bookies' favourite at one stage.

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