Latest news with #Comirnaty
Yahoo
10-07-2025
- Business
- Yahoo
Pfizer, BioNTech ask UK court to overturn Moderna's COVID vaccine patent win
LONDON (Reuters) -Pfizer and its German partner BioNTech asked London's Court of Appeal on Thursday to overturn a ruling that their COVID-19 vaccine infringed one of Moderna's patents, in the latest round of a long-running legal dispute between the two sides. A year ago, the High Court ruled that one of Moderna's two patents relating to the messenger RNA (mRNA) technology that underpinned its COVID-19 vaccine was valid and that Pfizer and BioNTech's Comirnaty vaccine had infringed it, meaning Moderna is entitled to damages in relation to sales after March 2022. The court also ruled last July that the other Moderna patent under challenge in the case was invalid. Pfizer and Moderna are seeking to overturn the decision that one of the patents is valid, after Judge Richard Meade gave the two companies permission to appeal against his decision. They argue Moderna's developments of mRNA technology were obvious developments of previous work, rendering the patent invalid, though Moderna says the judge's ruling should be upheld. Pfizer and BioNTech generated more than $3.3 billion in revenue from global sales of their vaccine Comirnaty last year, while Moderna generated $3.2 billion from its vaccine Spikevax, according to company reports. Sales of both vaccines declined significantly between 2023 and 2024 after the pandemic ended. Pfizer and BioNTech had sued Moderna in London in September 2022, seeking to revoke the two patents held by Moderna, which hit back days later alleging its own patents had been infringed. The London lawsuits are just one part of a global battle between Pfizer, BioNTech and Moderna over their competing vaccines, which helped save millions of lives during the pandemic. The companies have also been involved in proceedings in Germany – where a court ruled in Moderna's favour in March – the United States Patent Office, which held that two Moderna COVID-19 vaccine patents were invalid, and elsewhere. Sign in to access your portfolio
Yahoo
09-07-2025
- Business
- Yahoo
Pfizer Earnings Preview: What to Expect
With a market cap of $145.7 billion, Pfizer Inc. (PFE) is a global, research-driven biopharmaceutical company, specializing in the discovery, development, and commercialization of innovative medicines and vaccines across diverse therapeutic areas. With a strong late-stage pipeline and strategic partnerships, Pfizer maintains a robust presence in both established and emerging healthcare markets. The New York-based company is slated to announce its fiscal Q2 2025 results before the market opens on Tuesday, Aug. 5. Ahead of the event, analysts predict Pfizer to report an adjusted EPS of $0.57, down 5% from $0.60 in the year-ago quarter. However, the company has surpassed Wall Street's bottom-line estimates in the past four quarterly reports. In Q1 2025, PFE exceeded the consensus adjusted EPS estimate by 43.8%. This Underdog AI Stock Just Got a New Street-High Price Target Nvidia Scores Another Sovereign AI Win. How Should You Play NVDA Stock Here? Covered Call ETFs Are Popular, But My Favorite Options Trade Is Even Better Tired of missing midday reversals? The FREE Barchart Brief newsletter keeps you in the know. Sign up now! For fiscal 2025, analysts expect the drugmaker to report adjusted EPS of $3.06, a decline of 1.6% from $3.11 in fiscal 2024. Nevertheless, adjusted EPS is anticipated to grow nearly 1% year-over-year to $3.09 in fiscal 2026. Shares of Pfizer have dropped 8.2% over the past 52 weeks, lagging behind both the S&P 500 Index's ($SPX) 11.9% rise and the Health Care Select Sector SPDR Fund's (XLV) 7.1% decrease over the same period. Shares of Pfizer rose 3.2% on Apr. 29 after the company reported Q1 2025 adjusted EPS of $0.92, beating the consensus estimate and rising 12% year-over-year. Despite an 8% revenue decline to $13.7 billion, investors reacted positively to strong performance from key products like Comirnaty, Vyndaqel family, and Padcev. Additionally, Pfizer reaffirmed its full-year 2025 guidance, projecting revenue between $61 billion - $64 billion and EPS of $2.80 - $3, signaling confidence in its pipeline and cost control. Analysts' consensus rating on Pfizer stock is moderately optimistic, with a "Moderate Buy" rating overall. Among 22 analysts covering the stock, six recommend a "Strong Buy,' one has a "Moderate Buy" rating, 14 give a "Hold" rating, and one suggests a "Strong Sell.' This configuration is slightly less bullish than three months ago, with seven analysts suggesting a "Strong Buy." As of writing, the stock is trading below the average analyst price target of $27.71. On the date of publication, Sohini Mondal did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. This article was originally published on
Newsweek
04-07-2025
- Health
- Newsweek
Myth-Busters—Vaccine Edition
Advocates for ideas and draws conclusions based on the interpretation of facts and data. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. Vaccines are among the most rigorously tested and effective tools in modern medicine, yet myths and misinformation persist. Here, we address some of the most common claims with science-backed facts. Claim 1: Vaccine Ingredients Like Mercury or Thimerosal Are Harmful Thimerosal, a mercury-based preservative, was once used in multi-dose vaccine vials to prevent contamination. Thimerosal breaks down into ethylmercury, which does not accumulate in the body and is not the same as the toxic methylmercury found in certain fish. Thimerosal has been removed from nearly all vaccines in the United States since 2001, except for some flu vaccines, and extensive studies show no evidence of harm at the doses used in vaccines. Conclusion? Myth. Claim 2: Vaccines Cause Autism The belief that vaccines cause autism originated from a 1998 study by Andrew Wakefield, which was later retracted due to fraud and ethical violations. Large-scale studies involving hundreds of thousands of children have found no link between vaccines and autism. The timing of autism diagnosis often coincides with the vaccination schedule, but correlation does not mean causation. Conclusion? Myth. An immunization nurse holds a Pfizer-BioNTech COVID-19 vaccine (brand name: Comirnaty) at Borinquen Health Care Center on May 29, 2025, in Miami, Fla. An immunization nurse holds a Pfizer-BioNTech COVID-19 vaccine (brand name: Comirnaty) at Borinquen Health Care Center on May 29, 2025, in Miami, 3: COVID-19 Vaccines Cause Cancer Some rumors claim COVID-19 vaccines cause "turbo cancer" due to mRNA or SV40 fragments. However, mRNA from vaccines cannot enter the cell nucleus or alter DNA. There is no scientific evidence linking COVID-19 vaccines or SV40 fragments to cancer. mRNA is also naturally present in all foods and is harmless when consumed. Conclusion? Myth. Claim 4: Governments Exaggerate Disease Threats to Push Vaccines Vaccines have saved an estimated 154 million lives in the past 50 years. Diseases like smallpox, which once killed 30 percent of those infected, have been eradicated thanks to vaccination. When vaccination rates drop, diseases return, as seen in recent measles outbreaks. Public health guidelines are based on decades of research, not political agendas. Conclusion? Myth. Claim 5: Homeopathy and Supplements Can Replace Vaccines Homeopathic remedies and supplements have not been shown to trigger an immune response or prevent disease like vaccines do. Even most homeopathic practitioners support vaccination, and Faculty of Homeopathy explicitly recommends vaccines as first-line protection. Conclusion? Myth. Claim 6: Healthy Children Are at Higher Risk of Dying from Infections If Not Vaccinated Before the measles vaccine was introduced in 1963, hundreds of children died from measles each year in the U.S. After widespread vaccination, deaths dropped by over 99 percent. Recent outbreaks in unvaccinated communities show that risk returns when vaccination rates fall. Conclusion? Truth. Why This Matters Misinformation about vaccines has real consequences. As of June 2025, three people have died from measles in the U.S. this year—more than any year in the previous decade. Other children who have caught the measles without getting the vaccine first will be at risk of other complications including brain inflammation later on in life. This is why it's important to trust credible sources and follow science-backed recommendations. Vaccines have been rigorously tested, reviewed, and monitored for decades. They are one of the greatest success stories in medicine, saving lives and preventing suffering. If you have questions about vaccines, talk to a trusted health care provider—don't rely on social media or Dr. Google. Protect yourself, your children, and your community. Dr. Annalicia Pickering is a board-certified pediatrician on faculty at Stanford University. Niharika Rane is a Masters of Public Health student at Johns Hopkins Bloomberg School of Public Health. Akul Shrivastava, Srilalitha Nair, and Sahngwie Yim are youth volunteers with the American Red Cross. The views expressed in this article are the writers' own.
Economic Times
26-06-2025
- Health
- Economic Times
FDA issues new heart risk warnings for Pfizer, Moderna COVID vaccines - should you be worried?
What's Behind the FDA's New Warning? Who Faces the Highest Risk? Live Events What's Changing in the Vaccine Labels? What's the FDA Doing Next? FAQs (You can now subscribe to our (You can now subscribe to our Economic Times WhatsApp channel The US Food and Drug Administration (FDA) has warned that COVID-19 vaccines, which are manufactured by Pfizer and Moderna, have the potential for cardiac risks, as per a warnings were first proposed in letters, which were sent to both companies in April, providing additional information about the potential risks of myocarditis and/or pericarditis associated with the two vaccines, as reported by the Cardiovascular Business report. Myocarditis and pericarditis have the possibility of leading to long-term heart damage, according to the READ: Meet Trapit Bansal, Meta's new AI superintelligence team hire - Is Meta poaching top talent from OpenAI? FDA's latest update covers Pfizer's Comirnaty vaccine and Moderna's Spikevax vaccine, while both companies had mentioned text about myocarditis and pericarditis in the labelling for these vaccines since 2021, but the FDA wanted more information added to these warnings that specifically mentions the increased risks for young men, as per the Cardiovascular Business READ: After Canada, now US: College graduates face the toughest job market in decades – what's gone wrong? According to the Cardiovascular Business report, the new labeling for both the vaccines is now required to include the following text, as per FDA's latest update:"Based on analyses of commercial health insurance claims data from inpatient and outpatient settings, the estimated unadjusted incidence of myocarditis and/or pericarditis during the period 1 through 7 days following administration of the 2023-2024 Formula of mRNA COVID-19 vaccines was approximately 8 cases per million doses in individuals 6 months through 64 years of age and approximately 27 cases per million doses in males 12 through 24 years of age," as quoted in the label should also include, "Follow-up information on cardiovascular outcomes in hospitalized patients who had been diagnosed with COVID-19 vaccine-associated myocarditis is available from a longitudinal retrospective observational study. Most of these patients had received a two-dose primary series of an mRNA COVID-19 vaccine prior to their diagnosis. In this study, at a median follow-up of approximately 5 months post-vaccination, persistence of abnormal cardiac magnetic resonance imaging (CMR) findings that are a marker for myocardial injury was common. The clinical and prognostic significance of these CMR findings is not known," as quoted by the Cardiovascular Business READ: Top economist warns: US faces a crisis worse than recession — here's what could be coming While, FDA has also emphasised that it plans to keep tracking the safety of COVID-19 vaccines from now on, as per the agency said, 'Continuous monitoring and assessment of the safety of all vaccines, including the mRNA COVID-19 vaccines, is an FDA priority and we remain committed to informing the public when we learn new information about these vaccines,' adding, 'In addition, as part of the approvals of Comirnaty and Spikevax, each manufacturer is required by FDA to conduct a study to assess if there are long-term heart effects in people who have had myocarditis after receiving an mRNA COVID-19 vaccine. These studies are underway,' quoted by the Cardiovascular Business FDA wants the public to have clearer information about rare heart-related risks linked to COVID-19 mRNA vaccines, especially for young men, as per the Cardiovascular Business the FDA continues to support their use, but these warnings are about rare side effects, as per the Cardiovascular Business report.
Time of India
26-06-2025
- Health
- Time of India
FDA issues new heart risk warnings for Pfizer, Moderna COVID vaccines - should you be worried?
The US Food and Drug Administration (FDA) has warned that COVID-19 vaccines, which are manufactured by Pfizer and Moderna, have the potential for cardiac risks, as per a report. What's Behind the FDA's New Warning? These warnings were first proposed in letters, which were sent to both companies in April, providing additional information about the potential risks of myocarditis and/or pericarditis associated with the two vaccines, as reported by the Cardiovascular Business report. Myocarditis and pericarditis have the possibility of leading to long-term heart damage, according to the report. ALSO READ: Meet Trapit Bansal, Meta's new AI superintelligence team hire - Is Meta poaching top talent from OpenAI? by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Play War Thunder now for free War Thunder Play Now Undo Who Faces the Highest Risk? FDA's latest update covers Pfizer's Comirnaty vaccine and Moderna's Spikevax vaccine, while both companies had mentioned text about myocarditis and pericarditis in the labelling for these vaccines since 2021, but the FDA wanted more information added to these warnings that specifically mentions the increased risks for young men, as per the Cardiovascular Business report. ALSO READ: After Canada, now US: College graduates face the toughest job market in decades – what's gone wrong? Live Events What's Changing in the Vaccine Labels? According to the Cardiovascular Business report, the new labeling for both the vaccines is now required to include the following text, as per FDA's latest update: "Based on analyses of commercial health insurance claims data from inpatient and outpatient settings, the estimated unadjusted incidence of myocarditis and/or pericarditis during the period 1 through 7 days following administration of the 2023-2024 Formula of mRNA COVID-19 vaccines was approximately 8 cases per million doses in individuals 6 months through 64 years of age and approximately 27 cases per million doses in males 12 through 24 years of age," as quoted in the report. The label should also include, "Follow-up information on cardiovascular outcomes in hospitalized patients who had been diagnosed with COVID-19 vaccine-associated myocarditis is available from a longitudinal retrospective observational study. Most of these patients had received a two-dose primary series of an mRNA COVID-19 vaccine prior to their diagnosis. In this study, at a median follow-up of approximately 5 months post-vaccination, persistence of abnormal cardiac magnetic resonance imaging (CMR) findings that are a marker for myocardial injury was common. The clinical and prognostic significance of these CMR findings is not known," as quoted by the Cardiovascular Business report. ALSO READ: Top economist warns: US faces a crisis worse than recession — here's what could be coming What's the FDA Doing Next? While, FDA has also emphasised that it plans to keep tracking the safety of COVID-19 vaccines from now on, as per the report. The agency said, 'Continuous monitoring and assessment of the safety of all vaccines, including the mRNA COVID-19 vaccines, is an FDA priority and we remain committed to informing the public when we learn new information about these vaccines,' adding, 'In addition, as part of the approvals of Comirnaty and Spikevax, each manufacturer is required by FDA to conduct a study to assess if there are long-term heart effects in people who have had myocarditis after receiving an mRNA COVID-19 vaccine. These studies are underway,' quoted by the Cardiovascular Business report. FAQs Why is the FDA updating warnings now? The FDA wants the public to have clearer information about rare heart-related risks linked to COVID-19 mRNA vaccines, especially for young men, as per the Cardiovascular Business report. Are Moderna and Pfizer vaccines still considered safe? Yes, the FDA continues to support their use, but these warnings are about rare side effects, as per the Cardiovascular Business report.
