Latest news with #Contour
Business Wire
a day ago
- Health
- Business Wire
Galderma Unveils Final Nine-Month Data Showing Lasting Efficacy and Patient Satisfaction With Its Injectable Aesthetics Portfolio When Addressing Facial Aesthetic Changes After Medication-Driven Weight Loss
ZUG, Switzerland--(BUSINESS WIRE)--Galderma has revealed positive final data from a phase IV first-of-its-kind trial exploring the benefits of Restylane Lyft or Contour in combination with Sculptra to address the aesthetic concerns of patients experiencing facial volume loss associated with medication-driven weight loss. 1 These data reinforce that this treatment regimen can effectively improve facial aesthetic appearance with high patient satisfaction over nine months. 1 Rates of medication-driven weight loss have increased rapidly in recent years and can be associated with facial alterations of variable magnitude. 2-4 Patients may experience facial changes such as dry, dull or sagging skin, a gaunt or hollowed-out facial appearance, or other unwelcome alterations to facial structure and balance. 3,4 As the pure-play dermatology category leader, Galderma is spearheading efforts to identify and address the most predominant aesthetic concerns of patients along their weight loss journey. "At Galderma, we are leading the charge in redefining aesthetic care for patients impacted by medication-driven weight loss. Our commitment is clear: to empower individuals to reclaim their confidence through cutting-edge, data-driven innovation and strategic collaboration with the world's foremost experts, and these latest study results reinforce this mission." FLEMMING ØRNSKOV, M.D., MPH CHIEF EXECUTIVE OFFICER GALDERMA In the phase IV clinical study conducted in the U.S., Galderma investigated the aesthetic outcomes and appearance, and patient satisfaction of Restylane Lyft or Contour in combination with Sculptra for cheek or jawline augmentation and correction of contour deficiencies in patients experiencing facial volume loss associated with medication-driven weight loss. 1 The trial used the SHAPE Up Holistic Individualized Treatment (HIT™) – an individualized treatment approach which enables injectors to leverage their expertise with Galderma's Sculptra and its Restylane portfolio to optimize aesthetic outcomes while prioritizing patient satisfaction. Patients were treated with Sculptra and either Restylane Lyft or Contour for their first treatment, a second treatment of Sculptra with an optional touch-up of Restylane Lyft or Contour at Week 4, and an optional third treatment of Sculptra at Week 8. 1 Following interim analysis at three months presented earlier this year, a six-month extension study was conducted to capture the durability of treatment effects after nine months. In the extension study, follow-up visits took place at Weeks 32 and 44 for those who received the third Sculptra treatment and at Weeks 28 and 40 for those who did not, corresponding to nine months after their first Sculptra treatment. 1 Results at nine months demonstrated that the combination of Sculptra and Restylane Lyft or Contour effectively improved the aesthetic appearance of patients experiencing facial volume loss associated with medication-driven weight loss, further supporting the benefits of the SHAPE Up HIT: 1 The combined Sculptra and Restylane Lyft or Contour regimen demonstrated skin quality improvements, with Restylane improving skin hydration and Sculptra significantly improving skin radiance through to Month 9 1 Subject satisfaction – which was reported by the majority of patients as early as Week 4 – was maintained through to Month 9: 1 85.7% of patients said their face looked less gaunt/sunken 1 88.6% said they 'loved' how the treatment maintained their facial structure 1 88.6% of patients said they 'loved' the regenerative effects of Sculptra treatment 1 88.6% felt they looked better than before the injection regimen 1 91.4% said they would recommend the injection regimen to others after weight loss and to those with loose, sagging facial skin 1 Safety was in line with previous pivotal trial data for Sculptra, Restylane Lyft and Contour, with no treatment-related adverse events reports. 1 "The improvements we observed with Sculptra and Restylane at nine months are hugely encouraging and represent a meaningful step forward in addressing the most predominant aesthetic concerns of patients along their weight loss journey. It was exciting to see the glow we've clinically observed in the past with Sculptra now validated through innovative bioinstrumentation tools in this study. For physicians and patients who are navigating the visible effects of medication-driven weight loss, this study delivers real, evidence-based solutions that can make a tangible difference to how individuals look and feel." Z. PAUL LORENC, M.D. CLINICAL TRIAL INVESTIGATOR NEW YORK, UNITED STATES "These results really reinforce the role of aesthetic treatments, like Sculptra and Restylane, in supporting patients through their weight loss transformations, showing they can deliver visible improvements in skin quality while also significantly enhancing patient satisfaction and emotional wellbeing. The findings empower clinicians with data-backed tools to holistically address the nuanced aesthetic needs that arise with medication-driven weight loss, marking a pivotal moment where science meets patient-centered care." MICHAEL SOMENEK, M.D. CLINICAL TRIAL INVESTIGATOR WASHINGTON DC, UNITED STATES Galderma is spearheading multiple additional initiatives to identify and address the most predominant aesthetic concerns of patients who have experienced medication-driven weight loss through data-driven, innovative approaches in close collaboration with leading healthcare practitioners, as outlined in the company's recent report. 5 Galderma has supported pioneering research in the field, including the first recently published international consensus-based guidelines that provide a practical framework for practitioners to address the aesthetic needs of medication-driven weight loss patients, as well as research into the impact of medication-driven weight loss on the skin and the importance of factoring in aesthetic treatment goals during the patient journey. 6 * Restylane Contour is known as Restylane ® Volyme™ in countries outside of the U.S. About the study This phase IV trial was a multi-center, open-label study to evaluate the synergistic effects of Restylane Lyft or Contour in combination with Sculptra for cheek augmentation and correction of contour deficiencies, in patients experiencing facial volume loss following treatment with one of four brands of glucagon-like peptide-1 (GLP-1) receptor agonists. 1 Conducted in the U.S., the trial took place across two sites, and used the SHAPE Up Holistic Individualized Treatment (HIT) as a treatment methodology, with patients treated with Sculptra and either Restylane Lyft or Contour for their first treatment, a second treatment of Sculptra with an optional touch-up of Restylane Lyft or Contour at Week 4, and an optional third treatment of Sculptra at Week 8. 1 About Galderma Galderma (SIX: GALD) is the pure-play dermatology category leader, present in approximately 90 countries. We deliver an innovative, science-based portfolio of premium flagship brands and services that span the full spectrum of the fast-growing dermatology market through Injectable Aesthetics, Dermatological Skincare and Therapeutic Dermatology. Since our foundation in 1981, we have dedicated our focus and passion to the human body's largest organ – the skin – meeting individual consumer and patient needs with superior outcomes in partnership with healthcare professionals. Because we understand that the skin we are in shapes our lives, we are advancing dermatology for every skin story. For more information: References Galderma. Data on file. Somenek M and Lorenc P. A multi-center, open-label study to evaluate the synergistic effects of biostimulator and dermal fillers for cheek augmentation and correction of contour deficiencies: Nine-month topline results. Mansour MR, et al. The rise of 'Ozempic Face': Analyzing trends and treatment challenges associated with rapid facial weight loss induced by GLP-1 agonists. JPRAS. 2024;96:225-227. doi: 10.1016/ Tay JQ. Ozempic face: A new challenge for facial plastic surgeons. JPRAS. 2023;81:97-98. doi: 10.1016/ Humphrey CD and Lawrence AC. Implications of Ozempic and other GLP-1 receptor agonists for facial plastic surgeons. Facial Plast Surg. 2023;39:719-721. doi: 10.1055/a-2148-6321 Galderma. Balancing The Scales: Advancing Aesthetics In The Era Of Medication-driven Weight Loss Transformations. July 2025. Available online Nikolis A, et al. Consensus Statements on Managing Aesthetic Needs in Prescription Medication-Driven Weight Loss Patients: An International, Multidisciplinary Delphi Study. JCD
Elle
01-07-2025
- Entertainment
- Elle
2026's Biggest Beauty Trend? Looking Like You're in Love
Every item on this page was chosen by an ELLE editor. We may earn commission on some of the items you choose to buy. Marc Jacobs wants romance. But in Jacobs's world, romance doesn't mean fluffy florals, a hand graze, or a yearning stare. For 2026, romance is about adding levity, 'soft chaos,' and most importantly, valuing unique identities. This Jacobs-specific version came through in the beauty looks created by Pat McGrath and Duffy for the designer's runway show at the New York Public Library last night. 'Marc was obsessed with simple, absolute beauty,' McGrath said backstage. 'We used sheer blush, clumpy lashes, and subtle, powdery washes of baby blue or baby lilac on the lids. It's a nod to classic cosmetics imagery, but seen through Marc's lens, where romanticism meets rebellion. It's modern romanticism, a kind of soft chaos that's utterly captivating.' To help each model's natural features radiate, McGrath treated every face like a fresh canvas, infusing each with a youthful glow, a modern edge, and a touch of 'rawness.' This contrast created fresh, luminous looks for each model. They appeared as if they had just run through a meadow to meet their first love. They looked like they were flushed from being noticed by a crush. They were romance personified. McGrath called it 'poetic.' Though the looks for all 19 models were slightly different, they were cohesive—dewy skin, bright inner corners, and lots of blush. Each model had a playful, cherubic end result. 'We did FetishEYES Mascara on top and bottom of the lashes, soft contouring, and our gorgeous Glow Balms on the cheeks,' McGrath explained. From there, she mixed Legendary Long-Wear Lip Liners in the shades Contour and Rebel Rose, then blotted them to create a blurred-out, bitten lip. For the hair, uniqueness reigned—Duffy even went so far as to call his creations an 'army of individuality,' but with romantic elements to tie into Jacobs's vision. Duffy played with classic beauty, using roller sets, big hair accessories like bow accents, and braids to create undone waves and lots of length. At another show, these elements might have looked overplayed. 'In Marc's world, it doesn't look so classic,' Duffy said. All of this together served romance, with a modern twist. It's a nice reminder that the most loving gesture might be celebrating individuality—though a healthy dusting of blush never hurts.
Yahoo
03-06-2025
- Business
- Yahoo
Flights to Chicago O'Hare airport return to Greenbrier Valley Airport
LEWISBURG, WV (WVNS) – A highly requested flight route made a touchdown at the Greenbrier Valley Airport on Monday evening, June 2nd, 2025. A single Contour airplane made a safe landing onto the airports runway. Passengers and crew from Chicago were welcomed with a water cannon salute by two airport firetrucks. This was to welcome a returning flight route – Greenbrier Valley Airport to Chicago O'Hare airport. The last flight between both airports happened three years ago. WorkForce West Virginia announces upcoming Virtual Job Fair date Officials with the Greenbrier Valley Airport and Contour Airlines said they are happy to officially bring it back. It's been a couple of months to get it in place. We've been serving this airport since 2022 and have had an ongoing dialogue about getting Chicago services back in partnership with the airport and The Greenbrier.' President of Contour Airlines Ben Munson It's a great hub. You can get from Chicago and be any place you need to be. It's a great addition to our airport.' Airport Director at Greenbrier Valley Airport Martha Livesay Airport Director Martha Livesay said with summer in full swing, the welcoming of more tourists will be good for business across the Greenbrier Valley. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
The Spinoff
26-05-2025
- Entertainment
- The Spinoff
What's so great about Dungeons & Dragons?
This Friday, The Spinoff launches Fury of the Small, a D&D narrative podcast. Today, one of the podcast's players remembers her first time at the table. I was in the thick of my Big Breakup. Anyone who has been through their own Big Breakup knows exactly what I mean. It's the one where it feels like life is leading one way and you're merrily skipping down the path then BAM. Life, whole new direction. Crying in strange places. Hallway. On the floor. In the bathroom. I think everyone has a breakup like that? Or maybe will? It's like a rite of passage. The one that changes you. My friends wrapped around me in ways I still to this day deeply appreciate. One of the true blessings of the end of that romantic love was the absolutely thunderous, deepening love I felt for my friends. There were movies (In the Mood for Love being one of them, which was a terrible choice after a breakup, but a stunning film all the same), drinking, retreats and then one friend suggested I join his… Dungeons and Dragons Campaign. Dungeon? Dragons? Campaign? Join? It's hard to remember the exact images it conjured for me but I had a sense I was about to put myself in a situation where I felt stupid, sweaty or irritated. Or worse – all three. I also had a feeling it was like some sort of real-life video game, and I am not a gamer. Not because I don't want to be, it just wasn't a part of my childhood. We weren't really even a TV household, so anything with a console felt way out of my scope. Like any good 90s kid I snuck in a few happy reps of Golden Eye and Prince of Persia at friends' houses, but even I knew that wasn't a well-balanced diet, so I didn't really have anything to lean on when entering this world. But, as is often the way after a breakup, I had a lot of energy for trying new things, a lot of spare time, and zero desire to be alone. My first character was named Contour. Super strong. Not very smart. Got bonus points whenever they went into a rage (post-breakup catharsis anyone?). Even in this fantasy realm, no character can be good at everything (humbling) so you sort of make trade-offs. Good at hiding and sneaking around but maybe not so good up close and personal in a fight. There is something poetic about the fact that, in my eyes at least, the game works best if you have a mix of characters who all have different skill sets and histories. Not super deep, I know, but it's still a nice thought. I made the character by chatting to my friend about the vibe I thought I might enjoy, using films, books, animation as a way to be like 'he's a bit like this or a bit like that' and then my (very helpful) friend helped me figure out what Class that character could be. There's lots of options: Fighter, Druid, Bard, Rogue etc. I get the sense some people do it differently, but saying 'I think I want to be part actual energy of rock, part Drax from Guardians of the Galaxy and part gentle shepherd' worked well for me. So. I'd created my character. Borrowed some dice. Then went to join the Campaign. My friend was the dungeon master (to my mind a combo of MC, the person who voices all the background extras and supporting actors in a film, a dad who's telling you a story, and tech support). Six of us sat around a table, my friend set up the world, narrator style. 'You're at the docks, you smell the salty sea spray…' I started meeting other characters and for the first time I shyly tried out my Contour voice and traits. Putting on a voice felt strange at first. I'm an actor so this is ridiculous, but somehow sitting around a table putting on a voice for no reason feels different, and not in a good way. Similarly, it's really the pits for me if I tell someone I'm an actor and they make a joke about wanting to see me do a monologue (no thank you). I don't like feeling like I need to put on a show in my downtime, BUT after a little while, as with most times hanging out with my friends, those feelings slipped away and I was babbling like a happy child, voice on, playing for fun. Then it was time to start rolling some dice. (We're really in the thick of the nerd stuff now.) Each time you want to do anything in the game – and I mean anything, the world is your oyster – you state what you want to do out loud. For example, 'I want to lift this boulder'. The DM then usually says something like 'well that's a strength check', because, well, it would take strength to do it. In front of you is a piece of paper (or laptop screen) which has all your character's skills written on it, things like Strength, Charisma, Performance, Deception and a number next to them representing how good you are at any one skill. In Dungeons & Dragons, most often you're rolling a 20-sided die. You combine what your character's natural ability is at something (maybe it's plus 2) with what's on the die (let's say 14). That means overall your character has a roll of 16 to try and lift the boulder. The Dungeon Master has a number, a fair one, in mind that you are trying to beat. Basically the higher the number the more likely you are to succeed and if you roll a 20 on the 20-sided die it's almost impossible for you to fail. If a friend in the game says 'I'm helping' – which is the equivalent of an '..and my axe!' – you might get extra pluses. Which is just lovely. That first proper game was a lot. Even so, there were enough moments of joy across that first 5-ish hour(!) game that made me very happy to be there. True silliness and creativity for no one but ourselves. In the game, through the form of smart storytelling it becomes clear there's a quest/objective. A wizard needs help finding an apple pie recipe. Why is the castle collapsing? Where is the dragon hiding? You know – relatable problems like that. And all the characters must work together to sort it out. Later that first night, my friend said something along the lines of, 'This will probably take a year or so to complete'. A YEAR? I mean who has a year! In what world would I still be sitting around a table playing an imaginary fantasy game in a YEAR. I'm sure you can see where this is going. I played that campaign, for not one, but TWO years. I sat around my friend's table through the seasons changing both outside (obviously) and also inside my friends' lives, eating snacks and rolling dice through the highs and lows. As the monthly catch-ups became a staple I realised I wanted more. I joined another campaign. I had two going at once. One finished, I added another. I played confident types, sneaky types, happy-go-lucky types, 'I cast a lot of magic spells' types. I'd create characters on a whim based on what I thought would be fun or a challenge and then spend the following months experimenting with this persona in the two-to-four hour games. I couldn't believe who I'd become. In hindsight, there were actually some big clues that I'd love it. I grew up on fantasy books. It's only now in my 30s I've finally admitted to myself that when I'm on the beach I don't want a rom com. I would much rather be reading Ursula K. Le Guin, Tamora Pierce, Diana Wynne Jones. It's the stone labyrinth mystery cave hidden under a cloak identity life for me. And then of course Carrie Fisher made me want to act. So yes, duh. Fantasy is for me. And this isn't even mentioning that my family loves all board, dice and card games (as I said, not a big TV family). So anything competitive you can play over a table is good. Even now my parents will still play at least two games of something on any given day (their current faves are Splendour and Yahtzee). There were things that did and still do make me nervous. Being slow. Fumbling dice. Not knowing what to do. And the voices… I love listening to other people, but it still takes me a good hour to sink in and I'm usually changing the voice for the first few games till I actually find something I like for the character. But there are other things that have taken me by surprise. I love the escapism. I love using my imagination. I love not looking at my phone. I love being in a room with dear friends for two hours laughing and not talking about work. Hell, I even love the snacks! Recently, it's become a delightful connection with my brother-in-law. As I was writing this I googled: What makes dungeons and dragons so popular. The internet replied with: What's so great about Dungeons and Dragons? Which if you ask me sounds a lot more salty than my original question, but the answers made sense nonetheless. D&D offers fun and educational benefits, including stress relief and mental health benefits. Breaking D&D rules can lead to memorable gameplay and encourage critical thinking. D&D can strengthen friendships and maintain connections, serving as more than just a game. I couldn't agree more. It's funny what you picture for yourself after a breakup. I'm not going to go into all the R-rated details of what I had in mind but suffice to say sitting around a table with sparkly dice yelling, 'Investigation check!! I want to investigate this goblin's cave!' was not it. Sure, D&D's not for everyone. In fact, I really thought it wasn't for me. Turns out I was wrong.
Yahoo
18-05-2025
- Business
- Yahoo
Trump administration's proposed $300M cut to Essential Air Service could ground Tupelo flights
TUPELO – Air service in Tupelo could be affected by a drastic cut in the Essential Air Service program, which provides subsidized air service in 177 smaller communities around the country. Besides the All-America City, the proposed cut would affect two other Mississippi cities: Greenville and Hattiesburg. The Trump administration's budget proposal released earlier this month seeks to slash federal spending and includes a $300 million reduction to EAS. At the end of 2024, the Department of Transportation provided EAS subsidies worth nearly $592 million to the 177 communities. "The EAS program funnels taxpayer dollars to airlines to subsidize half-empty flights from airports that are within easy commuting distance from each other, while also failing to effectively provide assistance to most rural air travelers," the administration says in its budget proposal. "Spending on programs is out of control, more than doubling between 2021 and 2025. The budget reins in EAS subsidies by proposing a mix of reforms to adjust eligibility and subsidy rates to help rural communities' air transportation needs in a more sustainable manner." The budget doesn't outline what steps it would take to initiate reform nor identifies which communities would be affected by the cut or what would replace EAS. Tupelo Airport Authority board chairman Eric Gibens said the board is monitoring the situation closely. "Any cuts are a concern," he said. "Contour has been successful, and when they review that, they will see the flights are needed here. Hopefully, they look at the numbers and see their flights are for business and leisure and our flights are full. We'll definitely keep an eye on it, but it's wait and see at this point" Tupelo has taken part in the EAS program since 2009 after Northwest Airlines, followed by Delta Airlines, ended their regional flights to Memphis and Atlanta. Following the unsatisfactory performance from two airlines from 2009-2015, a new airline, Contour, stepped up in April 2016. It has provided air service since, and passenger enplanements, or boardings, have soared. In Tupelo, Contour has recorded at least 10,000 boardings in seven of the eight full years it has provided service. The only exception was in 2020, with the start of the pandemic. Currently, Contour provides daily round-trip flights to Nashville and Dallas. Through the first three months of this year, boardings were up 37% compared to a year ago. Contour's four-year contract, which began last October and runs through Sept. 30, 2028, has an annual subsidy of $6,924,450 in the first year, with a yearly increase of 5% in each of the next three subsequent years. Mississippi's two U.S. Senators said they support EAS and hope the administration backs off from talk of drastic cuts to its funding. 'It is not unusual for administrations to suggest that EAS be terminated. However, there is strong bipartisan support for this program, and I am confident the House of Representatives and Senate will continue our strong support," said U.S. Sen. Roger Wicker. In statements to U.S. Department of Transportation Secretary Sean Duffy, U.S. Sen. Cindy Hyde-Smith expressed her disappointment with the proposed budget cut to the EAS program. 'I was disappointed to see that the administration proposes drastic cuts to the Essential Air Service program. As we have discussed, the EAS program connects our nation's rural communities to the broader transportation network by facilitating safe air travel for customers traveling to and from smaller markets like in Greenville, Mississippi, Tupelo, and Hattiesburg, Mississippi,' Hyde-Smith told Duffy. 'I know you understand the importance of this program from your time as a congressman when you had multiple EAS-supported airports in your district. Drastically cutting this program will have a severe impact on EAS-supported rural communities and regions that rely on having access to the broader transportation network.' Hyde-Smith added that businesses rarely locate in areas without dependable commercial air service. 'Supporting these rural airports is vital for future economic development,' the senator said.
