Latest news with #Denali


Motor Trend
4 days ago
- Automotive
- Motor Trend
2026 GMC Acadia Denali Ultimate First Look: Fancy Name, a Few Fresh Features
For years, GMC's Denali trim level has represented the most expensive, nicest version of any given GMC model without stepping up to, well, a Cadillac. And as Denali has grown ever more critical to boosting the brand's bottom line (a surprising number of GMCs are Denali-spec examples), GMC has been naturally looking for ways to keep customers spending. One of those ways has been through the addition of the Denali Ultimate trim level, a step above package initially offered for the Yukon full-size SUV and Sierra 1500 pickup truck that's now being extended to the 2026 GMC Acadia lineup. The 2026 GMC Acadia Denali Ultimate adds premium features to the Acadia Denali, including a 16-speaker Bose system, 22-inch wheels, Woodland Mahogany leather seats, Paldao wood trim, and unique exterior details like a Vader chrome grille and LED start-up sequence. This summary was generated by AI using content from this MotorTrend article Read Next Similar in scope to the Sierra's Denali Ultimate treatment, the Acadia's Ultimate makeover brings a smattering of uprated features and materials to the mix. The standard Bose audio system, for example, sprouts four additional speakers (for a total of 16) versus the regular Acadia Denali, while the wheels grow from 20 inches in diameter to 22. GMC slathers the seats and door panels in a rich-looking brown Woodland Mahogany leather with contrast stitching and what first appears to be western-style filigree patterns but are actually 'topographical maps' on the seats. Those chairs are heated and ventilated up front, and massaging. This special leather is joined by laser-etched and embossed Paldao wood trim on the dashboard and door panels. Occupants' feet rest on special floor mats, too. Outside, the Acadia Denali Ultimate is set apart by a Vader chrome grille and trim, along with special Denali Ultimate badges. The LED running lamps can play a special start-up sequence as the Acadia is started, as well. If this tonier three-row SUV sounds good, prepare to shell out more than GMC charges for the regular Acadia Denali (for 2025, that's $58,090 with all-wheel drive), though how much more specifically will be shared closer to the Acadia Denali Ultimate's rollout date later this year. In some ways, this might be the only way to get a fancy GM three-row that isn't full-sized or electric—Cadillac is expected to axe the XT6, the Acadia's distant relative, and go all-in with the all-electric Vistiq. Otherwise, if you want three rows and gas power, you're looking at either a Yukon or an Escalade.

Miami Herald
5 days ago
- Automotive
- Miami Herald
Should GMC's Rivals Worry About the Upcoming 2025 Acadia Denali Ultimate?
The Acadia has always been a luxurious SUV. Even at the base level, for $43,000, it comes with a punchy 2.5-liter turbocharged four-cylinder engine producing 328 horsepower, an updated Bose sound system, GMC's comprehensive safety suite, and can be equipped with GM's impressive semi-autonomous feature, Super Cruise. Depending on how you configure it, it can also seat up to 8. For $54,100, you can get the Denali, which is even fancier. Leather seats, a nicer heads-up display, and higher-quality interior materials all complete the package. At that price, it looks like the Toyota Highlander, Hyundai Palisade, Chevy Traverse, and Kia Telluride are directly in GMC's crosshairs. Recently, GMC announced the addition of the Denali Ultimate trim. Which, if you could believe it, brought GMC's flagship SUV to all-new heights of luxury. With styling changes on the outside and the inside, added technology, and creature comforts, the Acadia's top-shelf model turned up the sumptuousness, right when we all thought it wasn't possible. So, should GMC's key rivals be concerned? The answer truly depends on what it will cost when official pricing is announced closer to its autumn launch. At the very least, the aforementioned automakers should be paying close attention to what we do know. The most apparent changes are to the features list, but I feel we should discuss the stylistic changes first. On the outside, the grille is darker, painted in what GMC calls "Vader Chrome." As a Star Wars nerd, the ashy chrome color felt appropriate. The badge is darker, there are LED daytime running lights with animated lighting sequences, fancy badging, and 22-inch wheels with an equally galactic metallic finish. The seats are all-leather, complete with massaging capabilities, and beautiful contrast stitching. Genuine wood is included, too, and GMC had maps etched into the seat backs. The door trim, map pockets, and floor mats all have "Denali Ultimate" badging. The Denali Ultimate will also feature a 16-speaker Bose sound system, Super Cruise, a large panoramic sunroof, a large, customizable heads-up display, and "performance" suspension. It also has six different drive modes to choose from. They haven't been announced, but I'd wager they'd be Sport, Eco, Normal, Off-Road, Towing/Hauling, and Snow. Official pricing hasn't been announced either, but if I were to guess, the added technology over the Denali and styling changes will likely bring the price close to $70,000 without add-ons. The Americans have always been competing with Japanese SUVs. First it was the RAV4, then the 4Runner, and now the updated Highlander. The one thing Toyota has over GMC, however, is the hybrid option for the Platinum model. With Toyota, buyers can choose between a gas-only engine or a hybrid option. As an AWD hybrid, the Highlander still earns around 30 mpg combined, and much higher overall range before needing a refill. The GMC Acadia, even if it's bought as an FWD SUV, earned around 23 mpg combined. All-wheel drive diminishes that slightly. If we focus on the gas-only price point for the Highlander to make it more fair, the Toyota comes out ahead. The base MSRP for the Highlander is $36,420, while the Acadia starts at $38,195. For higher-end models, the GMC has a higher price of $57,595 for the Denali, while the Highlander's top-shelf MSRP is $52,725 for the Platinum. With the higher resale value, reputation for longevity, and lower entry price, the Toyota is hard to beat. As a gas-only vehicle, the Highlander has the same towing rating of 5,000 lbs, too, so the only thing the GMC has over the Toyota is maybe buyer loyalty, interior design, and materials. Toyota's interiors are notoriously plain. Otherwise, I don't think Toyota should be too concerned, especially since the Denali Ultimate will likely be significantly more expensive than the Platinum, or even the Hybrid Platinum. For some reason, Hyundai has lagged behind in offering the Palisade as a hybrid. The Santa Fe's hybrid model is a best seller for the brand, so putting that setup in the Palisade would only make sense (though I argue a 1.8-liter engine seems a bit small for a large SUV, but maybe that's just me). The Palisade is one of my favorite family SUVs, due to its size and long list of features for the price. The Night edition is especially nice, since every car looks good with black accenting. I love the V6 that's in the Palisade, but it's not the most efficient. When the Palisade gets the hybrid treatment for 2026, I'm sure it'll sell even better than the standard Palisade. Since the GMC Acadia, once again, does not come as a hybrid and GMC has made exactly zero announcements on whether or not it will come as a hybrid, buyers are stuck with the 2.5-liter turbo four for now. That's fine since it makes more power and has the same towing rating as an engine with two more cylinders, so it truly comes down to whether or not a buyer trusts Hyundai or GMC more as a brand. Since Hyundai's reliability ratings are improving and its warranty is superior, I'm not sure Hyundai should be overly concerned, especially with a hybrid version coming down the pike. The Palisade is quite fancy in the upper trim levels, too, so it's hard to say there's much the GMC has over it. Price-wise, the Hyundai comes out ahead, too. As a gas-only SUV, the prices range from $40,430 for the base SE model, and go up to $55,555 for the Calligraphy model. As a hybrid, the price starts at $45,155 for the SEL Blue and goes up to $57,775 for the Calligraphy trim. Which, I'm guessing, will still come under the Denali Ultimate's upcoming price announcements. Since the Palisade is longer, taller, and has more passenger space than the GMC, the Hyundai is a pretty easy choice. Chevy and GMC may swap recipes here and there since they're both companies under the General Motors umbrella, but the Traverse and the Acadia are two different beasts. Yes, they're both 3-row SUVs, but the Traverse is a tad larger, leaving more room for passengers and their cargo. Similar to the GMC, the Chevy also has a 2.5-liter turbo four, making the same 328 horsepower. The Chevrolet is obviously going to run a little bit cheaper and come with a more minimalistic interior, although the Traverse does come with a bigger infotainment screen than the GMC. The GMC is smaller, but it feels more refined and has a much more upscale interior. By cheaper, though, I should say marginally cheaper. The Traverse starts at $42,195, while the GMC starts at $43,000. So, for a bit more dough, you sacrifice a bit of cargo space, but you get a lot more technology, higher-quality interior materials, a nicer sound system, a more performance-oriented ride, better fuel economy, and a more elegant design language. The Chevy is a lot more rugged and rustic. If you're looking at higher trim levels, they're priced pretty similarly. The ZL1, which is second from the bottom, runs around $49,295, and the RS starts at $55,595. The Denali's base MSRP is, according to GMC's site, the exact same as Chevy's RS trim if you opt for FWD, and $57,595 if you get AWD. Since Chevy doesn't have a step above the RS trim for the Traverse, in this case, Chevy will have a lot of work to do to catch up to the level of pizazz in the Denali Ultimate. The Traverse doesn't come in a hybrid, at least not yet, so the Chevy is the GMC's direct competition. Until Chevy unleashes an equally snazzy trim level, the GMC will be ahead of the game. Chevy should pay very close attention to the Denali Ultimate, no doubt. The Kia Telluride is another reasonably popular family SUV. It's spacious without being overly large, the third row is pretty roomy (even for adults), it boasts a very tech-forward interior, and there are enough trim levels to make just about anyone happy. The GMC Acadia's lineup is much more refined, while being known for its interior and ride quality. The Kia is bigger by about three inches all around and has more overall cargo space. However, if power is what you're looking for, the GMC is the answer. The Kia comes with a 3.8-liter V6 (for now) that offers 291 horsepower. The Kia Telluride can certainly be fancy, especially at the top-of-the-line SX Prestige X-Pro model, which starts at $53,685 and is noticeably less than GMC's $57,595 for the Denali. However, Kia's reputation is still recovering from its reputation for catching on fire and being fairly easy to steal. Kia's warranty is the best in the industry, though, so at least if your Telluride caught on fire or something failed, there's a 99.9% chance it would be covered under warranty. GMC's reputation isn't stellar either, but until people stop assuming the new Telluride can't be stolen with a screwdriver or spontaneously combust, the Telluride should certainly be nervous about the new Denali Ultimate trim. While we don't have pricing information about the 2025 GMC Acadia Denali Ultimate yet, its luxury touches could very well make it a strong competitor for the models listed above. If a hybrid engine joins the fray, that would make the newest Acadia an even stronger competitor in the luxury SUV segment. Copyright 2025 The Arena Group, Inc. All Rights Reserved.
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Travel + Leisure
6 days ago
- Travel + Leisure
National Parks Attendance Is Higher Than Ever—Here's What to Pack for Your Next Visit
If you plan on visiting one of America's national parks this year, you're not alone. According to the National Park Service, 2025 is on track to set new record highs for park attendance, with Yellowstone National Park seeing over 560,000 park guests this past May alone. As someone who has explored more than 50 national park sites, from the sun-baked chasms of Grand Canyon National Park to the misty peaks of Olympic National Park, I've learned which items are true non-negotiable essentials for casual visits. For treks through the sticky heat of the Everglades, the wind-blasted ridges of Badlands, and the alpine expanses of Denali, the right gear makes all the difference. And the good news is, you don't have to blow your budget on expensive gadgets to stay cool, comfortable, and safe at the parks. Keep scrolling to see my 15 must-have essentials for visiting nearly any site in the epic National Park Service network, including foldable hiking packs, blister-preventing wool socks, and waterproof first aid kits, starting at $10. A quality daypack that can hold everything is a must, and I love this ultra-light Eddie Bauer Stowaway backpack for the job. This packable backpack unfolds from its own pocket in seconds, so you can easily stow it in a larger heavy-duty pack for daily use on longer adventures, too. Weighing in at just 0.6 lb, this pack has a ripstop polyester build that avoids snags and protects your gear without weighing you down. Extended shoulder straps and a hip belt add surprising comfort for longer hikes, and the StormRepel water-resistant finish holds up to showers so your gear stays dry. With a roomy 20-liter capacity for layers and snacks, it's my standby for easy days at any national park site. These rugged low-top Nortiv 8 hiking shoes pair a synthetic leather upper with a waterproof membrane to keep your feet dry on wet trails. A breathable mesh lining helps reduce sweat during warm hikes, while a rubber toe cap and reinforced heel add protection and stability on uneven ground. The lightweight design doesn't sacrifice durability, and the flexible, removable insole keeps my feet comfortable even on longer walks. Finished with a non-slip outsole for solid traction across dirt paths or rocky overlooks, they're a practical choice for exploring national park sites between serious journeys that require clunkier boots. These polarized sunglasses cut harsh glare while enhancing vibrant, crisp colors, so the park views look as good in real life as they do on postcards. The UV400 lenses block every ray the sun throws at you, while lightweight TR90 frames and flexible hinges mean no pinching or slipping, even on sweaty uphill treks. I drop my pair constantly, and if the scratch-resistant lenses can survive my carelessness, they can definitely handle yours. And at the low price point of $34, you can afford not to be worried about your shades, anyway. This lightweight long-sleeve top packs UPF 50 sun protection ala Columbia's Omni-Shade fabric, so your skin is covered even on trails that offer zero shade. Omni-Wick technology pulls sweat off your skin fast, keeping you dry from hot climbs to sunny boardwalks. The breathable blend doesn't cling, and the classic fit layers easily over tees or under jackets when temps drop. Reinforced stitching means it's tough enough for repeated park visits, making it an easy pick when you want sun protection and comfort without extra bulk. And while it may be designed for fishing, reviewers agree that it's great for hiking, too. Staying hydrated while exploring the parks is easy with this insulated Owala FreeSip bottle that keeps water icy cold, even on exposed ridgelines. The FreeSip spout makes it simple to switch from quick sips to big gulps (I've never had to slow down my pace to drink from it). A locking lid prevents leaks in your pack, and the carry loop is perfect for hauling it between lookouts. The wide mouth handles ice without fuss, and cleaning is painless thanks to the dishwasher-safe lid, making this a reliable companion for any trail adventure. Keeping your feet happy on the trail is easy with these wool-blend hiking socks that breathe well and stay comfortable mile after mile. Light cushioning softens every step without adding bulk, so I never worry about blisters, even on rocky switchbacks. The crew height shields ankles from boot rub, while the snug fit prevents slipping or bunching. They wick moisture fast to keep feet dry, and durable knit zones last up to seasons of use despite their affordable cost. One reviewer calls them 'the best wool blend socks around,' adding that they're the only socks they wear now, no matter the weather or time of year. Even in the summer, mornings and evenings in the desert or mountains can be quite chilly—or sometimes, downright cold. Staying warm on the trails without sacrificing too much space is easy with a packable puffer on hand. The ultra-light insulation of this Outdoor Ventures puffer creates a cozy layer that keeps out the chill on cold trailheads. When you're done wearing it, simply fold it neatly back into its own pocket for out-of-the-way stashing. Stylish enough for town but substantial enough for basecamp, this jacket is my go-to layer for outdoor fun. Shielding your face and neck from the sun is easy with this waterproof, baseball‑style sun cap that's built for all-day comfort. As the brim shades your eyes, the extended flap protects your neck from UV rays; come sunset, it can be comfortably folded up into the cap. One reviewer says it's even lighter than a traditional baseball cap, and the breathability eliminates that head-sauna feeling even in heat. Roomy enough for wider heads, the adjustable strap keeps it comfy no matter your size and secure no matter the wind level. The quick-dry fabric handles morning dew or light rain with no fuss, too. A scraped knee or hot-spot blister won't ruin your day if you've got a proper first-aid kit on deck. I usually bring this Hart Outdoor First Aid Kit with me while visiting national parks, but this similar option by Rhino Rescue has many of the same supplies inside. This featherweight kit tucks 114 essentials into a slim, clippable pouch. The Moleskine patches can help prevent blisters before they start, and the waterproof exterior prevents gauze, bandages, and cotton swabs from getting soaked on rainy days. With burn gel, a disposable tourniquet, and an emergency blanket ready to go, it's surprisingly thorough, and the sturdy zip case slips unnoticed onto or into any pack. Even if you plan on making it back to your car or campsite before sundown, it's important to keep a light source on hand. Continuing onward in low light is easy with this twin-pack of Energizer headlamps, on sale for 47 percent off. These headlamps pack 260 lumens into a compact water-resistant shell, illuminating the trail ahead of you. The dimming dial and three beam modes—wide, spot, and red—let you dial in the perfect amount of light, while the 35-hour battery life will keep you going long into the night. Every second counts in an emergency, and this piercing 120-decibel whistle can help ensure your call for help won't go unheard. Three sound chambers produce a powerful, attention-grabbing whistle that blasts in multiple directions and can reach rescuers even over heavy wind or rushing water. Available in multiple vibrant colors, this small, waterproof whistle visually stands out while clipped to your hiking bag or keys, keeping you safe and prepared for every hike, paddle, or alpine scramble. Juice up your phone with an extra charge or two on the trail thanks to this rugged, compact power bank that delivers 9600 mAh of power. It's rated IP67 for full dust and waterproof protection and comes with a built-in, 50‑lumen flashlight. Weighing in at just over 10 ounces and compact enough to slip into a jacket pocket, this nifty power bank has three ports that allow you to top off multiple devices at once. For unexpected rain, camp showers, or dips in the lake, this Rainleaf towel gets you dry again quickly. At 48 inches long, it's big enough for head-to-toe drying, but is made with a microfiber material that rolls up into a small, packable pouch. It soaks up nearly five times its weight and dries out quickly, so you won't have any smelly, moldy fabrics hanging out in your bag. I love how the suede-like material feels on my skin, and it doubles just as well as a beach towel or small picnic blanket, too. Keeping your hands warm without adding bulk is easy with these slim, stretchy New Balance gloves. Lined with soft fleece, these gloves have a silicone grip pattern that helps you to hold your gear and gadgets securely, and touchscreen-ready thumbs and index fingers let you check park maps or snap photos without exposing skin. Easily stuffed in your pocket once the sun climbs, these gloves combine warmth, dexterity, and packability for crisp mornings spent exploring the parks. This mini multitool keeps me ready for the small surprises a park day can throw my way. The butterfly-open design gives quick access to tweezers for bee stings or wooden splinters, and sharp scissors for clipping trail tape or loose threads—all while staying impressively lightweight. Compact and durable, it's a simple way to stay prepared for resolving small snags and enhance your first-aid gear without adding bulk to your bag. Love a great deal? Sign up for our T+L Recommends newsletter and we'll send you our favorite travel products each week.
Yahoo
6 days ago
- Business
- Yahoo
Nicox and Kowa Sign Key Agreement worth up to €191.5 million for Exclusive Rights to Glaucoma Treatment NCX 470 in U.S. and all Unlicensed Territories
Press Release Nicox and Kowa Sign Key Agreement worth up to €191.5 million for Exclusive Rights to Glaucoma Treatment NCX 470 in U.S. and all Unlicensed Territories €7.5 million upfront, with total potential development and commercial milestones, depending on Denali trial results, of up to €191.5 million Tiered royalties of up to 20% in the U.S., starting at a minimum of 8%, with tiered high single to double digit royalties elsewhere Kowa will assume full responsibility for the preparation and filing costs of the U.S. NDA for NCX 470, and all future development and commercial costs Provides flexibility for Nicox to explore future growth options July 17, 2025 – release at 7:30 am CET Sophia Antipolis, FranceNicox SA (Euronext Growth Paris: FR0013018124, ALCOX), an international ophthalmology company, today announced the signing of a major new agreement concerning NCX 470 with Kowa Company, Ltd., a Japanese company with a global pharmaceutical business engaged in ground-breaking research, development and marketing. The agreement, worth up to €191.5 million, grants Kowa exclusive rights to develop and commercialize NCX 470, Nicox's nitric oxide (NO)-donating bimatoprost eye drop, for the lowering of intraocular pressure (IOP) in patients with glaucoma or ocular hypertension in the U.S. and all other territories of the world excluding Japan, China, Korea and Southeast Asia. Kowa already has a license to NCX 470 for Japan, where it is preparing to enter a Phase 3 clinical trial. NCX 470 is also licensed to Ocumension Therapeutics for China, Korea and Southeast the terms of the agreement, Nicox will receive an upfront payment of €7.5 million on signing. Additional near-term milestones payments are due on positive topline results from the Denali clinical trial, expected mid-August to mid-September 2025, and on submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA), which is currently expected in H2 2026. The total potential development and sales milestones payments will be either €127 million or €191.5 million, depending on the outcome of the Denali clinical trial, plus royalties up to 20% in the U.S. 'This new agreement with our existing partner, Kowa, is a major endorsement of NCX 470's potential in glaucoma and marks a major step forward in strengthening Nicox's financial position. With NCX 470 now globally licensed, we are focused on delivering the Denali Phase 3 results, which we anticipate releasing mid-August to mid-September.' said Gavin Spencer, Chief Executive Officer of Nicox. 'The revenue stream we expect from NCX 470 gives us the flexibility to pursue future growth opportunities, leveraging our expert U.S. ophthalmology development team.''Expanding our collaboration with Kowa, who now becomes our key commercial partner for NCX 470 in the U.S and other major territories, is based on a very successful history of working together. We believe that Kowa has recognised the significant market potential of NCX 470, which we expect to be confirmed with the upcoming results from the Denali Phase 3 trial.' said Emmet Purtill, VP Business Development of Nicox. 'We look forward to continuing to work with Kowa as well as our partner for the Chinese market, Ocumension, to bring NCX 470 to glaucoma patients worldwide.' Details of the AgreementUnder the terms of the exclusive licensing agreement, Kowa is granted rights to develop and commercialize NCX 470 worldwide, excluding the territories already licensed to Ocumension (China, Korea and Southeast Asia) and to Kowa itself (Japan). The collaboration will be managed by a Joint Steering Committee. Key terms include:Milestone PaymentsNicox will receive an upfront payment of €7.5 million upon signing the agreement. Additional near-term milestones payments are due on positive topline results from the Denali Phase 3 clinical trial, expected mid-August to mid-September 2025 and upon submission of an NDA to the FDA, which is currently expected in H2 2026. The total potential development and sales milestones payments will be either €127 million or €191.5 million, depending on the outcome of the Denali clinical trial. Royalty PaymentsKowa will pay Nicox tiered royalties in the U.S. which could reach 20% of net sales. Depending on the results of the Denali clinical trial, royalties due in the U.S. will initially be 8% or 10%. Outside of the U.S., Nicox will receive tiered royalties ranging from single-digit to double-digit percentages. Nicox ObligationsNicox is responsible, at its cost, for generating the remaining development data necessary for the NDA submission to the FDA (principally pharmacokinetic studies) and will support Kowa in preparation of the ObligationsOther than the activities for which Nicox is responsible, Kowa is responsible, at its cost, for all development, regulatory and commercialization activities for NCX 470 in the licensed Runway and Debt RepaymentAs disclosed in the amended bond agreement announced on 14 October 2024, 70% of the upfront payment from Kowa will be used to partially reimburse Nicox's debt, reducing the total debt to €9.6 million. Based on the current cash position (estimated1 at €5.9 million as of 30 June 2025) expected revenue and anticipated milestone payments, Nicox forecasts that it has over 12 months of cash at the date of signature of this agreement. Glaucoma Pharmaceutical MarketThe glaucoma pharmaceutical market is estimated at over $7 billion2, with the U.S. market accounting for around 40%, growing globally at around 3% to 5% CAGR and the number of patients globally is estimated to be around 80 million3. About NCX 470NCX 470, Nicox's lead clinical product candidate, is a novel NO-donating bimatoprost eye drop, currently in Phase 3 clinical development in the U.S., China and Japan (clinical trial authorisation granted for Japan) for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension. Results of Mont Blanc, the first of the Phase 3 clinical trials, have been extensively published and are available on our website. The second Phase 3 clinical trial, Denali, is currently ongoing. The last patient in Denali has completed their final visit, and the results are expected mid-August to mid-September 2025. Mont Blanc and Denali have been designed to fulfil the regulatory requirements for safety and efficacy Phase 3 trials to support NDA submissions in both the U.S. and in China. All remaining NDA-enabling pharmacokinetic and non-clinical studies necessary to support the U.S. NDA filing are on track. A separate Phase 3 program is underway to support Japanese approval, with the first patient expected to be enrolled in H2 2025. NCX 470 is exclusively licensed to Ocumension Therapeutics in China, Korea and Southeast Asia, and to Kowa in the rest of the world. About Nicox Nicox SA is an international ophthalmology company developing innovative solutions to help maintain vision and improve ocular health. Nicox's lead program in clinical development is NCX 470 (bimatoprost grenod), a novel nitric oxide-donating bimatoprost eye drop, for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension, licensed to Ocumension Therapeutics for the Chinese, Korean and Southeast Asian markets and to Kowa elsewhere. Nicox also has a preclinical research program on NCX 1728, a nitric oxide-donating phosphodiesterase-5 inhibitor, with Glaukos. Nicox's first product, VYZULTA® in glaucoma, licensed exclusively worldwide to Bausch + Lomb, is available commercially in the U.S. and over 15 other territories. Nicox generates revenue from ZERVIATE® in allergic conjunctivitis, licensed in multiple geographies, including to Harrow, Inc. in the U.S., and Ocumension Therapeutics in the Chinese and in the majority of Southeast Asian markets. Nicox, headquartered in Sophia Antipolis, France, is listed on Euronext Growth Paris (Ticker symbol: ALCOX) and is part of the CAC Healthcare index. For more information Analyst coverage H.C. Wainwright & Co Yi Chen New York, views expressed by analysts in their coverage of Nicox are those of the author and do not reflect the views of Nicox. Additionally, the information contained in their reports may not be correct or current. Nicox disavows any obligation to correct or to update the information contained in analyst reports. Contacts NicoxGavin SpencerChief Executive OfficerT +33 (0)4 97 24 53 00communications@ Disclaimer The information contained in this document may be modified without prior notice. This information includes forward-looking statements. Such forward-looking statements are not guarantees of future performance. These statements are based on current expectations or beliefs of the management of Nicox S.A. and are subject to a number of factors and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Nicox S.A. and its affiliates, directors, officers, employees, advisers or agents, do not undertake, nor do they have any obligation, to provide updates or to revise any forward-looking factors which are likely to have a material effect on Nicox's business are presented in section 3 of the 'Rapport Annuel 2024' which is available on Nicox's website ( this press release may be drafted in the French and English languages. If both versions are interpreted differently, the French language version shall prevail. Nicox Sophia Antipolis, Bâtiment C, Emerald Square, Rue Evariste Galois, 06410 Biot, FranceT +33 (0)4 97 24 53 00 1 Non-audited figure 2 Antiglaucoma Drug Market Size, Trends, Growth Report 2034; Glaucoma Therapeutics Market Report by Drug Class (Prostaglandin Analogs, Beta Blockers, Alpha Adrenergic Agonists, Carbonic Anhydrase Inhibitors, Combination Drugs, and Others), Indication (Open Angle Glaucoma, Angle Closure Glaucoma, and Others); Glaucoma Therapeutics Market Size, Growth, Analysis - 20313 World Glaucoma Association website: World Glaucoma Association » What is glaucoma? Attachment EN_NCX470KowaGlobalLicenseJuly2025_PR_FINALError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data


Auto Blog
11-07-2025
- Automotive
- Auto Blog
2026 GMC Acadia Price Increases Come With New Colors
By signing up I agree to the Terms of Use and acknowledge that I have read the Privacy Policy . You may unsubscribe from email communication at anytime. Acadia Up To $1,600 Pricier The new GMC Acadia arrived in 2023 as a larger vehicle with more length, height, and cargo capacity. For 2026, the only thing that will be getting bigger is the price, according to order guide data uncovered by CarsDirect. The publication reports that the luxury SUV will now start at $43,700 (excluding $1,495 for destination) in base Elevation form, an increase of $700 over the 2025 sticker. The other two trims in the range, however, get heftier raises of $900 on the mid-level model and $1,600 on the range-topper. The mid-range AT4 model now starts at $52,300, while the epitome of luxury in the range, the Denali, costs $55,700, representing an increase of 2.96%. These adjustments are not unusual for an annual pricing update, and to soften the blow, they don't arrive alone, with a new key card now being standard and a pair of new paint options – Glacier White Tricoat and Riverstone Metallic – joining the palette. The former costs $1,095 on the Sierra EV and the Terrain, while the latter is no more than $495, so we expect the same prices for the Acadia. GMC Acadia Trim MY2025 Price MY2026 Price Difference Elevation $43,000 $43,700 +$700 AT4 $51,400 $52,300 +$900 Denali $54,100 $55,700 +$1,600 Standard equipment includes a 2.5-liter turbocharged engine delivering 328 horsepower and 326 lb-ft of torque, a Bose Premium 12-speaker sound system, and a 15-inch infotainment display alongside an 11-inch driver cluster. Buyers not swayed by the appeal of the GMC badge may wish to consider the Chevrolet Traverse, which is very similar beneath the skin and starts at $40,995 for the 2025 model year. Of course, that may get a price bump for 2026, too, but it will still offer much of the same at a lower price point. What Rivals In The Same Segment Cost The Acadia has plenty of competitors in the midsize SUV segment, even if some of them don't aspire to quite the same levels of luxury as the GMC brand. Across town is the Ford Explorer, which currently starts at $39,625 for 2025, while Japan's Toyota Highlander and Honda Pilot start at $43,630 and $40,200, respectively. There's also the Kia Telluride to consider, which starts at $36,390. This will likely become more expensive for the 2026 model, which will bring with it numerous changes, but we still expect it to remain competitive. Autoblog Newsletter Autoblog brings you car news; expert reviews and exciting pictures and video. Research and compare vehicles, too. Sign up or sign in with Google Facebook Microsoft Apple By signing up I agree to the Terms of Use and acknowledge that I have read the Privacy Policy . You may unsubscribe from email communication at anytime. About the Author Sebastian Cenizo View Profile