Latest news with #Enayat
Indian Express
20-06-2025
- Health
- Indian Express
41-year-old doctor claims to be biologically 24, reveals the three ‘core' supplements behind his age reversal
Dr Mohammed Enayat, a 41-year-old primary care doctor based in London, claims that his biological age is just 24 — 17 years younger than his chronological age. The founder of the longevity-focused Hum2n clinic says he's been tracking his health for seven years using wearables, along with frequent blood, urine, and microbiome testing. 'While I believe these supplements have supported my biological age reversal, I credit them as one component in a much broader framework,' Dr Enayat told Business Insider, pointing to daily doses of 'core' supplements such as vitamin B complex with folate, magnesium, and omega-3 fatty acids as part of his routine. Dr Enayat said he takes vitamin B complex and folate due to a methylation gene defect that causes elevated homocysteine levels, which raises the risk of heart attack and stroke. 'Even without a methylation-related gene defect, I would still consider taking a methylated B complex, particularly during periods of high stress, poor sleep, or intensive training, as these increase the demand for B vitamins,' he added. On magnesium, he opts for bisglycinate due to better absorption, reporting reduced muscle aches and better sleep. For omega-3 fatty acids, he supplements due to low levels and notes their potential anti-ageing and anti-inflammatory effects. speaks to an expert to verify the efficacy. Dr Jagadish Hiremath, public health intellectual, says, 'Biological age tests such as GlycanAge and TruAge PACE can offer some insight into the impact of lifestyle, stress, and inflammation on the body's physiological state. These tests generally evaluate biomarkers correlating with cellular ageing or immune function, which differs from traditional diagnostics.' However, he adds that while the science behind these tools is evolving, they are not yet universally standardised across populations. Their interpretation requires nuance and should not be viewed as standalone indicators of health or risk. 'For the average person, these tests can serve as a supplementary checkpoint, but health decisions should still be grounded in regular clinical assessments and evidence-based screenings,' states Dr Hiremath. Methylated B vitamins are more bioavailable forms, Dr Hiremath informs, particularly helpful for individuals with genetic variations such as MTHFR polymorphisms. 'For those without such variants or a clinically diagnosed deficiency, taking a B complex occasionally during periods of high stress is unlikely to be harmful, but over-supplementation is unnecessary and may cause side effects in some cases, such as headaches or gastrointestinal upset,' he explains. The key is mindful dosing and timing. Vitamins should support a balanced diet, not replace it. If someone is considering supplements during stressful periods, a conversation with a healthcare provider can ensure the approach is both safe and targeted. Dr Hiremath says, 'Magnesium and omega-3 fatty acids are among the most researched and commonly used supplements with benefits ranging from cardiovascular health to sleep support. However, their necessity should ideally be determined by assessing dietary intake, lifestyle habits, and individual health needs.' Blood tests can identify deficiencies, but even in their absence, some individuals, such as those with sleep issues or limited fish intake, might benefit from short-term supplementation. The goal should always be to supplement if needed, not as a blanket solution for everyone. Finally, Dr Hiremath asserts, 'Supplements can play a supportive role, but they are just one piece of the puzzle. A complex interplay of factors, including genetics, nutrition, physical activity, sleep, stress management, and social connection influences longevity.' DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.
Irish Examiner
13-06-2025
- Health
- Irish Examiner
Our bodies' biological age: No simple ‘hack' to change how lifestyle and time treat us
IT'S no secret that wellness fads come as quickly as they go. From the low-fat diets of the noughties to the UPF-free food of today, society loves indulging in the newest health hack. The newest wellness trend to emerge is 'biohacking'. You may have heard of it via American entrepreneur Bryan Johnson's infamous anti-ageing quest, or simply by the numerous podcasts that now discuss cell health and biological age. But what really is biohacking? How do you find out your biological age? And does it really determine how long you'll live for? Doctors specialising in stem cell and longevity research explain what biological age really means, how to lower it, and why it's fast becoming the ultimate wellness metric in modern medicine. What is biological age? Biological age — a measurement of how well your body is functioning based on factors like lifestyle, stress, and cellular health — is different to chronological age, as it isn't fixed and you can reverse it. According to longevity experts, biological age provides a more accurate picture of health span than the candles on our birthday cake. And increasingly, it's being treated as something we can influence. The CEO of Cellcolabs, Dr Mattias Bernow, who provided the stem cells for biohacker Bryan Johnson, explains that this measurement is 'a marker of how old your body seems based on your health, lifestyle, and cellular function.' In other words, you might be 50 on paper, but living like someone 35 — or 65. 'Two people who are both 40 years old chronologically might have very different biological ages depending on how they live, their stress levels, their metabolic health and more,' says GP and the founder of longevity clinic HUM2N, Dr Mohammed Enayat. The biggest culprits behind accelerated ageing are changeable: chronic stress, poor sleep, lack of exercise, ultra-processed foods, and environmental toxins are major accelerants. What accelerates biological ageing? The good news is that many of the biggest culprits behind accelerated ageing are changeable. Both Enayat and Bernow point to chronic stress, poor sleep, lack of exercise, ultra-processed foods, and environmental toxins as major accelerants. Parenting itself doesn't inherently age the body but, as Enayat points out, the chronic sleep deprivation and stress associated with caregiving certainly can. Inflammation is another central player. 'These factors contribute to increasing low-grade inflammation,' Bernow explains, 'which plays a key role in age-related decline and the development of chronic disease.' However, he says, this process is not set in stone. 'While we can't control everything, small, consistent changes to reduce these stressors can make a meaningful difference in how we age.' Which lifestyle changes have the strongest scientific backing? When it comes to slowing the clock, it turns out the best advice isn't ground-breaking – it's just often overlooked. Quality sleep, regular physical activity, a balanced whole-food diet, meaningful relationships, and avoiding harmful substances all rank highly on the evidence-based list. Enayat also points to practices such as caloric moderation, intermittent fasting, and resistance training for their 'strong results in slowing biological ageing at a cellular level'. However, these diets impact each sex differently, with intermittent fasting in particular causing more stress on women's bodies while being effective for men, meaning they will affect biological age differently. Though it's tempting to think of ageing as a genetic lottery, our DNA doesn't write the full script. How big a part do genetics play? Though it's tempting to think of ageing as a genetic lottery, our DNA doesn't write the full script. 'Genes load the gun, but lifestyle pulls the trigger,' Enayat says, noting that genetics may only account for 20 to 30% of ageing outcomes. Bernow says that emerging research suggests as much as 80% of ageing is governed by one's environment and behaviour. Supplements can claim everything from healthier skin to better energy to thicker hair — but it's fair to be sceptical of whether they really make a difference, or if it's all marketing. Do supplements make a difference? Supplements can claim everything from healthier skin to better energy to thicker hair — but it's fair to be sceptical of whether they really make a difference, or if it's all marketing. However, there are some supplements that have been proven to be helpful if taken correctly and absorbed properly. 'Protein is essential for preserving muscle mass,' says Enayat, while collagen 'may help with skin and joint health,' though its systemic anti-ageing benefits are modest. Fish oil, magnesium, creatine, and polyphenols all show promise too, but Enayat is keen to emphasise that supplements should support — not replace — healthy habits. Bernow cautions that while some supplements, like vitamin D, are well-supported (especially in sun-deprived regions), many products on the market are poorly regulated. 'Supplements are not a substitute for healthy habits,' he says, 'but in some cases, they can play a supportive role if used thoughtfully.' How to find out your biological age? If you're curious to find out your own biological age, figuring it out requires a blood test. 'The most validated tests look at DNA methylation patterns,' says Enayat, and suggests well-known tests like the Horvath Clock, GlycanAge, and TruAge. Bernow says that Bryan Johnson uses the DunedinPace test, which claims to show he's ageing at just 0.66 years per calendar year (66% of his chronological age). As for how these experts practise what they preach, they say it's all about balance and consistency. Enayat's daily habits include walking, strength training, or stretching, prioritising plants and healthy fats, regular fasting, cold exposure, and supplementing with omega-3, vitamin D, magnesium, and creatine. 'The goal is consistency, not perfection,' he says. Bernow takes a similar approach, but with less exercise and more socialising — explaining he takes a short morning workout, has plenty of family time, eats balanced meals and drinks minimal alcohol. 'More than anything, I believe in consistency,' he says. 'Longevity isn't about extremes but about the things you do every day, for years.' So, while biohacking might conjure visions of futuristic and expensive tech, the real secret to ageing well is actually much simpler: Prioritise balance and relaxation. Read More Fast-track your fitness with five minutes of exercise each day
NDTV
11-06-2025
- Health
- NDTV
41-Year-Old Longevity Doctor Claims His Biological Age Is 24, Reveals 3 Supplements He Takes
A 41-year-old London-based primary care doctor has claimed his biological age is 24, thanks to his comprehensive routine and supplement regimen. According to tests taken 18 months ago, Dr. Mohammed Enayat's biological age was 17 years younger than his chronological age. He used GlycanAge and TruAge PACE tests, which measure inflammation and epigenetics, to determine his biological age. Notably, Dr. Enayat, founder of Hum2n longevity clinic, has tracked his health for seven years using wearables like Oura ring and Whoop strap, along with regular blood, urine, and microbiome tests. Based on the results, he adjusts his longevity routine, including supplements. His core supplements include daily cycles of B complex, folate, magnesium, and omega-3 fatty acids. "While I believe these supplements have supported my biological age reversal, I credit them as one component in a much broader framework," Mr Enayat told Business Insider. 1. Vitamin B complex Dr. Enayat said he takes vitamin B complex and folate supplements due to a methylation gene defect that causes elevated homocysteine levels, increasing his risk of blood clots, heart attack, and stroke. The supplements help lower these levels. Generally, dietitians recommend obtaining nutrients through food and supplementing only when necessary, such as in cases of deficiency or inability to consume certain nutritious foods. Foods rich in B vitamins, like fish, poultry, legumes, and leafy greens, can also help reduce homocysteine levels. Research suggests B vitamins may be linked to improved mood and dementia prevention, but further studies are required to confirm these findings. "Even without a methylation-related gene defect, I would still consider taking a methylated B complex, particularly during periods of high stress, poor sleep, or intensive training, as these increase the demand for B vitamins," Mr Enayat said. 2. Magnesium Dr. Enayat takes magnesium bisglycinate due to his naturally low magnesium levels from dietary intake. This form is chosen for its better absorption, helping to boost his levels. Magnesium is essential for bone health, blood sugar regulation, and muscle function, and can also be found in foods like legumes and leafy greens. He reported that taking magnesium helps reduce muscle aches and improves his sleep, allowing him to fall asleep more easily. 3. Omega-3 Fatty Acids Dr. Enayat takes a daily omega-3 supplement due to his naturally low levels. Omega-3s, found in oily fish, walnuts, and chia seeds, support heart health, reduce inflammation, and lower blood pressure. While eating fatty fish weekly is proven to protect against cardiovascular disease, the benefits of supplement form are less clear. However, some research suggests omega-3 supplements may have anti-ageing effects, with a recent study finding participants who took omega-3s daily had lower biological ages.
Time of India
11-06-2025
- Health
- Time of India
Meet the London doctor who is 41 but biologically 24; here's his secrets to living younger revealed
Some ageing signs around the age of 41 are most expected, like tiredness, slower metabolism and longer recovery. But, in contrast to the statement and common observations, Dr. Mohammed Enayat, a London primary care physician and creator of the HUM2N longevity clinic, is defying the diagnostics. With a cutting-edge and rigorous lifestyle regimen, according to the reports, Enayat says his biological age is only 24 which means 17 years younger than his real age. This happened not because of any magic pill or any cleansing but it is actually the result of self-tracking, scientific understanding and regimen of potent supplements. Biologically 17 years younger than his real age; Dr Enayat reveals his lifestyle secret Dr. Enayat has used his body as a living lab for the last seven years. He tracks his vital health data such as sleep, activity, and recovery using wearable tech like the Oura Ring and the Whoop strap. In addition to that, he takes regular in-depth tests on his blood, urine, and gut microbiome. These points enable him to adjust his diet, exercise regimes, and supplement intake with accuracy. To determine his biological age, Enayat uses sophisticated tools such as GlycanAge and TruAge PACE, which evaluate inflammation and epigenetic markers. His latest scan, done 18 months ago, revealed his biological age at 24. However, he emphasizes that supplements are just half the story: According to Business Insider reports: "While I think these supplements have aided my biological aging reversal, I attribute them as one piece in a much larger universe. " Which 3 core supplement constants used by Dr. Enayat While his supplement regimen changes according to the needs of his body, three have been the constants. These are his core supplements: B complex with folate, magnesium, and omega-3 fatty acids. B Complex with Folate Part of Dr. Enayat's daily supplement intake stems from an individual genetic concern, a methylation defect that causes homocysteine to accumulate, making inflammation and heart disease more likely. To counter this, he takes a methylated B complex with folate, which helps to bring homocysteine levels to normal. He also advises taking B vitamins during periods of high stress or inadequate sleep, when the body demands them. Possible advantages are: Improved mood and cognitive abilities Decreased inflammation Decreased risk of dementia Magnesium Even after consuming magnesium-fortified foods such as leafy greens and legumes, Dr. Enayat found that his magnesium levels were always low. He takes magnesium bisglycinate, a type that is highly absorbed and easy on the digestive system. He says: "When I take magnesium, my muscles hurt less and I go to sleep more easily." Magnesium aids in more than 300 enzymatic processes, and deficiency may not be evident. Even if a mere 2% of Americans are clinically deficient, many are functioning at less-than-optimal levels. Omega-3 fatty acids Famous for maintaining heart health, omega-3 fatty acids also lower systemic inflammation and maintain cognitive function. Although Enayat consumes omega-3-rich foods such as fish and walnuts, he supplements to guarantee daily consumption. According to the recent study published, Nature Aging discovered that adults who took 1 gram of omega-3 per day had biologically younger profiles than their counterparts who did not reflect its potential for longevity. Dr. Enayat introduces test-driven path to better health Dr. Enayat is part of a new generation of medical practitioners where clinical knowledge intersects with data-supported self-care. He neither suggests his regimen is one-size-fits-all nor advises everyone to follow the same steps. Rather, he suggests starting with testing, personalizing the process, and being persistent. "Supplements won't make you immortal," he concedes, "but when paired with wisdom and discipline, they can enable you to live younger, longer. " Do you also want to turn back your biological age? Maybe, with wise scientific strategies and foundational supplements anything more than you think might be possible. Also Read | Man mums in China earn Rs 600 for a 5-minute hug; who are they and what's behind this surprising new trend
Yahoo
10-06-2025
- Health
- Yahoo
A 41-year-old longevity doctor says his 'biological age' is 24. He takes 3 supplements daily.
Dr. Mohammed Enayat, the founder of a longevity clinic, says he's reversed his "biological age" by 17 years. He told Business Insider that supplements are a part of his longevity routine. He takes B complex and folate, magnesium, and omega-3 fatty acids daily. Dr. Mohammed Enayat has access to all sorts of experimental antiaging treatments at his clinic, but a core part of his longevity routine is pretty cheap and accessible: supplements. Enayat told Business Insider that his most recent "biological age" tests, taken 18 months ago, said he was 24, or 17 years younger than his chronological age of 41. There's no consensus on how to define or measure biological age, but Enayat used GlycanAge and TruAge PACE, which measure inflammation and epigenetics, respectively. The primary care doctor, who's also the founder of London's Hum2n longevity clinic, has been closely tracking his health for the past seven years, using wearable tech, including an Oura ring and a Whoop strap, plus regular blood, urine, and microbiome tests. Enayat changes his longevity routine, including the supplements he takes, depending on the results. But he has taken what he sees as his "core" supplements, B complex and folate, magnesium, and omega-3 fatty acids, daily in cycles over the past several years, he said. "While I believe these supplements have supported my biological age reversal, I credit them as one component in a much broader framework," Enayat added. In general, dietitians recommend that people prioritize getting their nutrients from food and supplementing if they have deficiencies or are unable to eat certain nutritious foods. Enayat takes a vitamin B complex and folate supplement. "I have a methylation gene defect, which means that my homocysteine, one of the markers, rises high, which is very pro-inflammatory. So to bring that down, I have to be on a good B complex and a folate supplement," he said. Having high levels of homocysteine can increase the risk of blood clots, heart attack, and stroke. But you can lower your levels through supplementation and eating foods that contain B vitamins, including fish, poultry, legumes, seeds, eggs, dairy products, and leafy greens. More broadly, studies have linked B vitamins to better mood and the prevention of dementia, but more research is needed. "Even without a methylation-related gene defect, I would still consider taking a methylated B complex, particularly during periods of high stress, poor sleep, or intensive training, as these increase the demand for B vitamins," Enayat said. Magnesium is found in legumes, dark leafy greens, nuts, seeds, and whole grains. It plays a key role in many biological processes, including building strong bones, regulating blood sugar and blood pressure, and muscle function. Enayat's magnesium is below the recommended level, he said, because he doesn't get enough from his diet. This is relatively uncommon — about 2% of Americans have low magnesium levels. For this, he takes a form of magnesium called bisglycinate because it's easier for the body to absorb. "It works really well to bring my levels up," he said. When he takes magnesium, he finds that his muscles ache less and he falls asleep more easily. Omega-3 fatty acids, found in foods including oily fish, walnuts, and chia seeds, have been linked to better heart health, lower inflammation, and lower blood pressure. Enayat has naturally low levels of omega-3 fatty acids, so he takes a daily supplement. There's strong evidence to suggest that eating fatty fish weekly is protective against cardiovascular disease, but it's unclear whether taking it in supplement form provides the same protection. There is, however, some evidence to suggest that taking omega-3 supplements may have antiaging effects. A study on 777 participants with an average age of 75, published in the journal Nature Aging earlier this year, found that those who consumed a gram of omega-3s every day had lower "biological ages" than those who didn't. Read the original article on Business Insider
